公开(公告)号：US20150320780A1

公开(公告)日：2015-11-12

申请号：US14651710

申请日：2013-12-13

Applicant: GLYCOM A/S

Inventor： Elise Champion ,  Gyula Dekany ,  Nikolay Khanzhin ,  Pierre Chassagne ,  Györgyi Osztrovszky

IPC: A61K31/7016 ,  A23L1/09 ,  A23L1/29 ,  C12P19/14 ,  C12P19/12

CPC classification number: A61K31/7016 ,  A23L5/00 ,  A23L7/00 ,  A23L29/30 ,  A23L33/10 ,  A23L33/125 ,  A23L33/40 ,  A23V2002/00 ,  A61K31/702 ,  C07H1/00 ,  C07H3/06 ,  C12P19/00 ,  C12P19/12 ,  C12P19/14

Abstract: A method to form a mixture containing at least one of 2′-FL (2′-O-fucosyllactose, Fuc(α1-2)Gal(β1-4)Glc) and 3-FL (3-O-fucosyllactose, Gal(β1-4)[Fuc(α1-3)]Glc) characterized in that DFL (difucosyl-lactose, Fuc(α1-2)Gal(β1-4)[Fuc(α1-3)]Glc) is subjected to partial hydrolysis, e.g. enzymatic hydrolysis or acid hydrolysis.

Abstract translation: 形成含有2'-FL（2'-O-岩藻糖基乳糖，Fuc（α1-2）Gal（＆bgr; 1-4）Glc）和3-FL（3-O-岩藻糖基乳糖）中至少一种的混合物的方法， Gal（＆bgr; 1-4）[Fuc（α1-3）] Glc），其特征在于DFL（二氟蔗糖 - 乳糖，Fuc（α1-2）Gal（＆bgr; 1-4）[Fuc（α1-3）] Glc ）进行部分水解，例如 酶水解或酸水解。

公开(公告)号：US12060594B2

公开(公告)日：2024-08-13

申请号：US16895871

申请日：2020-06-08

Applicant: Glycom A/S

Inventor： Gyula Dekany ,  Györgyi Osztrovszky ,  Martin Matwiejuk ,  Pierre Chassagne ,  Markus Jondelius Hederos

IPC: C12P19/18 ,  C07H1/06 ,  C07H3/06

CPC classification number: C12P19/18 ,  C07H1/06 ,  C07H3/06 ,  C12Y204/01069

Abstract: The invention relates to a method for selective crystallization of 2′-fucosyllactose (2′-FL) from an aqueous solution comprising 2′-FL and one or more other fucosylated carbohydrates by adding acetic acid to the solution. The aqueous solution is separated from an aqueous culture medium prior to crystallization.

公开(公告)号：US10676770B2

公开(公告)日：2020-06-09

申请号：US15536537

申请日：2015-12-16

Applicant: Glycom A/S

Inventor： Gyula Dekany ,  Györgyi Osztrovszky ,  Martin Matwiejuk ,  Pierre Chassagne ,  Markus Jondelius Hederos

IPC: C12P19/18 ,  C07H1/06 ,  C07H3/06

Abstract: The invention relates to a method for selective crystallization of 2′-FL from an aqueous solution comprising 2′-FL and one or more other fucosylated carbohydrates by adding acetic acid to the solution.