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公开(公告)号：US20190185455A1
公开(公告)日：2019-06-20
申请号：US16223845
申请日：2018-12-18
申请人： Gruenenthal GmbH
发明人： Florian JAKOB , Jo ALEN , Sebastian KRÜGER , Markus SCHADE , Daniela FRIEBE , Stephanie HENNEN
IPC分类号： C07D401/14 , C07D403/14 , C07D417/14 , C07D405/14 , A61P25/00 , A61P29/00
CPC分类号： C07D401/14 , A61P11/06 , A61P19/02 , A61P25/00 , A61P29/00 , C07D403/14 , C07D405/14 , C07D413/14 , C07D417/14
摘要： The invention relates to compounds according to general formula (I), which act as modulators of the glucocorticoid receptor and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by the glucocorticoid receptor.
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公开(公告)号：US20220106295A1
公开(公告)日：2022-04-07
申请号：US17554702
申请日：2021-12-17
申请人： GRUENENTHAL GMBH
发明人： Florian JAKOB , Jo ALEN , Sebastian KRUEGER , Daniela FRIEBE , Stephanie HENNEN
IPC分类号： C07D403/04 , C07D471/04 , C07D413/04 , C07D413/14 , C07D405/04 , C07D207/12 , C07D417/04
摘要： The invention relates to compounds according to general formula (I), which act as modulators of the glucocorticoid receptor and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by the glucocorticoid receptor.
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公开(公告)号：US20190185470A1
公开(公告)日：2019-06-20
申请号：US16223925
申请日：2018-12-18
申请人： Gruenenthal GmbH
发明人： Florian JAKOB , Jo ALEN , Sebastian KRÜGER , Markus SCHADE , Daniela FRIEBE , Stephanie HENNEN
IPC分类号： C07D471/04 , C07D409/14 , C07D403/14 , C07D413/14 , C07D417/14 , C07D401/14 , C07D405/14 , C07D403/04 , A61P29/00
CPC分类号： C07D471/04 , A61P11/06 , A61P19/02 , A61P29/00 , C07D401/14 , C07D403/04 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14
摘要： The invention relates to compounds according to general formula (I), which act as modulators of the glucocorticoid receptor and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by the glucocorticoid receptor.
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公开(公告)号：US20220396578A1
公开(公告)日：2022-12-15
申请号：US17866670
申请日：2022-07-18
申请人： GRUENENTHAL GMBH
发明人： Jo ALEN , Florian JAKOB , Sebastian KRUEGER , Daniela FRIEBE , Stephanie HENNEN
IPC分类号： C07D487/04 , C07D491/147 , C07D519/00
摘要： The present invention relates to compounds according to general formula (I) which act as modulators of the glucocorticoid receptor and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by the glucocorticoid receptor.
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公开(公告)号：US20220106294A1
公开(公告)日：2022-04-07
申请号：US17554729
申请日：2021-12-17
申请人： GRUENENTHAL GMBH
发明人： Florian JAKOB , Jo ALEN , Sebastian KRUEGER , Philipp BARBIE , Daniela FRIEBE
IPC分类号： C07D401/14 , C07D403/04 , C07D401/04 , C07D403/14 , C07D405/14 , C07D405/04
摘要： The invention relates to compounds according to general formula (I), which act as modulators of the glucocorticoid receptor and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by the glucocorticoid receptor.
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公开(公告)号：US20220372041A1
公开(公告)日：2022-11-24
申请号：US17866672
申请日：2022-07-18
申请人： GRUENENTHAL GMBH
发明人： Jo ALEN , Florian JAKOB , Sebastian KRUEGER , Philipp BARBIE , Daniela FRIEBE , Stephanie HENNEN
IPC分类号： C07D487/04 , C07D498/04 , C07D471/04 , C07D471/14 , A61P29/00
摘要： The present invention relates to compounds according to general formula (I) which act as modulators of the glucocorticoid receptor and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by the glucocorticoid receptor.
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公开(公告)号：US20200223840A1
公开(公告)日：2020-07-16
申请号：US16740735
申请日：2020-01-13
申请人： Gruenenthal GMBH
发明人： Florian JAKOB , Jo ALEN , Sebastian KRÜGER , Daniela FRIEBE , Stephanie HENNEN , Philipp BARBIE
IPC分类号： C07D417/14 , C07D403/10 , C07D471/04 , C07D409/14 , C07D403/14 , C07D413/14 , C07D401/14
摘要： The invention relates to compounds according to general formula (I), which act as modulators of the glucocorticoid receptor and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by the glucocorticoid receptor.
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