ANTIMICROBIAL COMPOSITIONS AND USES THEREOF
    6.
    发明申请
    ANTIMICROBIAL COMPOSITIONS AND USES THEREOF 审中-公开
    抗微生物组合物及其用途

    公开(公告)号:US20110034557A1

    公开(公告)日:2011-02-10

    申请号:US12709270

    申请日:2010-02-19

    CPC分类号: A61K31/22 A01N37/46

    摘要: Antimicrobial compositions and methods of using the compositions are described herein. The compositions include an antibacterial acyl amino acid. In some embodiments, the acyl amino acid is a fatty acylated glutamate. The methods herein include methods of using acyl amino acids for treating and preventing bacterial infections.

    摘要翻译: 本文描述了抗微生物组合物和使用组合物的方法。 组合物包括抗菌酰基氨基酸。 在一些实施方案中,酰基氨基酸是脂肪酰化谷氨酸。 本文的方法包括使用酰基氨基酸来治疗和预防细菌感染的方法。

    ENGINEERED MICROORGANISMS AND METHODS OF USE
    7.
    发明申请
    ENGINEERED MICROORGANISMS AND METHODS OF USE 审中-公开
    工程微生物及其使用方法

    公开(公告)号:US20110059487A1

    公开(公告)日:2011-03-10

    申请号:US12822765

    申请日:2010-06-24

    摘要: The present invention provides, among other things, engineered microorganisms and methods that allow efficient conversion of soy carbohydrates to industrial chemicals by fermentation. In some embodiments, the invention provides microbial cells engineered to have increased efficiency in utilizing a soy carbon source (e.g., soy molasses, soy meal, and/or soy hulls) as compared to a parent cell. In some embodiments, microbial cells are engineered to have altered (e.g., increased) expression or activity of one or more carbohydrate modifying enzymes (e.g., glycosidases). In some embodiments, microbial cells are engineered to have altered localization of carbohydrate modifying enzymes (e.g., glycosidases). In some embodiments, engineered microbial cells provided herein are used to produce industrial chemicals (e.g., surfactin) using soy components as primary or sole carbon sources.

    摘要翻译: 本发明尤其提供了工程微生物和允许通过发酵将大豆碳水化合物有效转化成工业化学品的方法。 在一些实施方案中,与亲本细胞相比,本发明提供了工程化以提高利用大豆碳源(例如大豆糖蜜,大豆粉和/或大豆皮)的效率的微生物细胞。 在一些实施方案中,将微生物细胞工程化以改变(例如增加)一种或多种碳水化合物修饰酶(例如糖苷酶)的表达或活性。 在一些实施方案中,将微生物细胞工程化以改变碳水化合物修饰酶(例如糖苷酶)的定位。 在一些实施方案中,本文提供的工程微生物细胞用于使用大豆成分作为主要或唯一碳源来生产工业化学品(例如表面活性素)。

    GROWTH OF MICROORGANISMS IN CELLULOSIC MEDIA
    8.
    发明申请
    GROWTH OF MICROORGANISMS IN CELLULOSIC MEDIA 审中-公开
    细胞培养中微生物的生长

    公开(公告)号:US20100093060A1

    公开(公告)日:2010-04-15

    申请号:US12565408

    申请日:2009-09-23

    IPC分类号: C12N1/20 C12N1/22

    CPC分类号: C12N1/20 C12P13/04 C12P21/02

    摘要: The present invention provides novel methods of growing of microorganisms in cell culture media comprising cellulosic material as a carbon source. The present invention further provides novel cell culture media cellulosic material as a carbon source. In certain embodiments, inventive cell culture media substantially lack a carbon source other than cellulosic material (e.g., the media substantially lack glucose and glycerol). In certain embodiments, inventive cell culture media comprise cellulosic material as the sole carbon source.

    摘要翻译: 本发明提供了在包含纤维素材料作为碳源的细胞培养基中生长微生物的新方法。 本发明还提供作为碳源的新型细胞培养基纤维素材料。 在某些实施方案中,本发明的细胞培养基质基本上不含除纤维素材料之外的碳源(例如,培养基基本上不含葡萄糖和甘油)。 在某些实施方案中,本发明的细胞培养基包含作为唯一碳源的纤维素材料。

    Growth of Microorganisms in Media Containing Crude Glycerol
    9.
    发明申请
    Growth of Microorganisms in Media Containing Crude Glycerol 审中-公开
    微生物在含有粗甘油的培养基中的生长

    公开(公告)号:US20090269832A1

    公开(公告)日:2009-10-29

    申请号:US12264491

    申请日:2008-11-04

    IPC分类号: C12N1/20 C12N1/16

    CPC分类号: C12N1/20 C12N1/16 C12P21/005

    摘要: The present invention provides novel methods of growing of microorganisms in cell culture media comprising crude glycerol as a carbon source. The present invention further provides novel cell culture media comprising crude glycerol as a carbon source. In certain embodiments, inventive cell culture media substantially lack refined glycerol. In certain embodiments, inventive cell culture media comprise crude glycerol as the sole carbon source.

    摘要翻译: 本发明提供了在包含粗甘油作为碳源的细胞培养基中生长微生物的新方法。 本发明还提供了包含粗甘油作为碳源的新型细胞培养基。 在某些实施方案中,本发明的细胞培养基质基本上不含精制甘油。 在某些实施方案中,本发明的细胞培养基包含粗甘油作为唯一的碳源。