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公开(公告)号:US10287356B2
公开(公告)日:2019-05-14
申请号:US15356483
申请日:2016-11-18
申请人: GENENTECH, INC.
发明人: Avi Ashkenazi , Jing Qing , Christian Wiesmann , Yan Wu
IPC分类号: C07K16/28 , C07K16/30 , A61K39/395 , A61K39/00
摘要: The invention provides FGFR3 antibodies, and compositions comprising and methods of using these antibodies.
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公开(公告)号:US08710189B2
公开(公告)日:2014-04-29
申请号:US13653293
申请日:2012-10-16
申请人: Genentech, Inc.
发明人: Avi Ashkenazi , Jing Qing , Christian Wiesmann , Yan Wu
CPC分类号: C07K16/2863 , A61K39/395 , A61K39/3955 , A61K39/39558 , A61K2039/505 , C07K16/3038 , C07K16/3061 , C07K2317/24 , C07K2317/34 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/732 , C07K2317/75 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2319/30
摘要: The invention provides FGFR3 antibodies, and compositions comprising and methods of using these antibodies.
摘要翻译: 本发明提供FGFR3抗体,以及组合物和使用这些抗体的方法。
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公开(公告)号:US10208120B2
公开(公告)日:2019-02-19
申请号:US14934059
申请日:2015-11-05
申请人: Genentech, Inc.
发明人: Yiyuan Yin , Avi Ashkenazi , Paul J. Carter , Mark Chen , Junichiro Sonoda
摘要: The invention provides dual specific anti-FGFR2 and FGFR3 (FGFR2/3) antibodies, and compositions comprising and methods of using these antibodies.
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公开(公告)号:US09358250B2
公开(公告)日:2016-06-07
申请号:US13651226
申请日:2012-10-12
申请人: Genentech, Inc.
发明人: Avi Ashkenazi , Xiangnan Du , Jing Qing
IPC分类号: A61K31/497 , A61K31/501 , A61K31/506 , A61K31/713 , A61K31/445 , A61K31/513 , A61K45/06 , A61K31/4355 , A61K31/496 , G01N33/50 , G01N33/574
CPC分类号: A61K31/713 , A61K31/4355 , A61K31/445 , A61K31/496 , A61K31/501 , A61K31/506 , A61K31/513 , A61K45/06 , G01N33/5011 , G01N33/57407 , G01N2510/00 , G01N2800/52
摘要: Provided herein are therapies for the treatment of pathological conditions, such as cancer, and method of using SCD1 antagonists.
摘要翻译: 本文提供了用于治疗诸如癌症的病理状况的治疗剂,以及使用SCD1拮抗剂的方法。
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公开(公告)号:US20130046078A1
公开(公告)日:2013-02-21
申请号:US13653293
申请日:2012-10-16
申请人: Genentech, Inc.
发明人: Avi Ashkenazi , Jing Qing , Christian Wiesmann , Yan Wu
IPC分类号: C07K16/28
CPC分类号: C07K16/2863 , A61K39/395 , A61K39/3955 , A61K39/39558 , A61K2039/505 , C07K16/3038 , C07K16/3061 , C07K2317/24 , C07K2317/34 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/732 , C07K2317/75 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2319/30
摘要: The invention provides FGFR3 antibodies, and compositions comprising and methods of using these antibodies.
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公开(公告)号:US09161977B2
公开(公告)日:2015-10-20
申请号:US13762252
申请日:2013-02-07
申请人: GENENTECH, INC.
发明人: Avi Ashkenazi , Jing Qing , Christian Wiesmann , Yan Wu
IPC分类号: A61K39/00 , A61K39/395 , C07K16/28
CPC分类号: C07K16/2863 , A61K39/395 , A61K39/3955 , A61K39/39558 , A61K2039/505 , C07K16/3038 , C07K16/3061 , C07K2317/24 , C07K2317/34 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/732 , C07K2317/75 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2319/30
摘要: The invention provides FGFR3 antibodies, and compositions comprising and methods of using these antibodies.
摘要翻译: 本发明提供FGFR3抗体,以及组合物和使用这些抗体的方法。
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公开(公告)号:US20130287776A1
公开(公告)日:2013-10-31
申请号:US13762252
申请日:2013-02-07
申请人: Genentech, Inc.
发明人: Avi Ashkenazi , Jing Qing , Christian Wiesmann , Yan Wu
IPC分类号: A61K39/395
CPC分类号: C07K16/2863 , A61K39/395 , A61K39/3955 , A61K39/39558 , A61K2039/505 , C07K16/3038 , C07K16/3061 , C07K2317/24 , C07K2317/34 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/732 , C07K2317/75 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2319/30
摘要: The invention provides FGFR3 antibodies, and compositions comprising and methods of using these antibodies.
摘要翻译: 本发明提供FGFR3抗体,以及组合物和使用这些抗体的方法。
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公开(公告)号:US20130096181A1
公开(公告)日:2013-04-18
申请号:US13651226
申请日:2012-10-12
申请人: Genentech, Inc.
发明人: Avi Ashkenazi , Xiangnan Du , Jing Qing
IPC分类号: A61K31/713 , A61K45/06 , A61K31/506 , A61K31/513 , A61K31/445 , A61K31/501
CPC分类号: A61K31/713 , A61K31/4355 , A61K31/445 , A61K31/496 , A61K31/501 , A61K31/506 , A61K31/513 , A61K45/06 , G01N33/5011 , G01N33/57407 , G01N2510/00 , G01N2800/52
摘要: Provided herein are therapies for the treatment of pathological conditions, such as cancer, and method of using SCD1 antagonists.
摘要翻译: 本文提供了用于治疗诸如癌症的病理状况的治疗剂,以及使用SCD1拮抗剂的方法。
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公开(公告)号:US09925240B2
公开(公告)日:2018-03-27
申请号:US15029960
申请日:2014-03-06
申请人: Genentech, Inc.
发明人: Robert L. Yauch , Xiaofen Ye , Avi Ashkenazi
IPC分类号: A61K31/517 , A61K31/519 , A61K38/17 , A61K45/06 , A61K31/5377
CPC分类号: A61K38/179 , A61K31/517 , A61K31/519 , A61K31/5377 , A61K45/06 , A61K2300/00
摘要: Provided herein are combination therapies for the treatment of pathological conditions, such as cancer, using an antagonist of FGFR signaling.
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公开(公告)号:US20170042967A1
公开(公告)日:2017-02-16
申请号:US15065777
申请日:2016-03-09
申请人: GENENTECH, INC.
发明人: Avi Ashkenazi , Karim Yussef Helmy , Sherman Fong , Audrey Goddard , Austin L. Gurney , Kenneth James Katschke, Jr. , Menno Van Lookeren , William I. Wood
IPC分类号: A61K38/17 , C07K14/705
CPC分类号: A61K38/177 , A61K38/17 , A61K38/1709 , A61K2039/505 , C07K14/705 , C07K16/28 , C07K2317/77 , C07K2319/30 , Y02A50/463 , A61K2300/00
摘要: The present invention concerns a recently discovered macrophage specific receptor, CRIg, and its use in the treatment of complement-associated disorders.
摘要翻译: 本发明涉及最近发现的巨噬细胞特异性受体CRIg及其在补体相关疾病的治疗中的应用。
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