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公开(公告)号:US20210284753A1
公开(公告)日:2021-09-16
申请号:US17094646
申请日:2020-11-10
Applicant: Genentech, Inc.
Inventor: Luc Desnoyers
IPC: C07K16/40 , C07K14/71 , G01N33/74 , G01N33/574 , A61K31/506 , A61K31/4745 , A61K31/4196 , A61K45/06 , A61K31/138 , A61K38/17 , A61K31/5685 , A61K31/565 , A61K31/517 , A61K31/475 , A61K39/395 , G01N33/50
Abstract: The invention concerns uses of anti-KLβ agents, and detection of KLβ and/or FGF19 and/or FGFR4.
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公开(公告)号:US20180208677A1
公开(公告)日:2018-07-26
申请号:US15701243
申请日:2017-09-11
Applicant: Genentech, Inc.
Inventor: Luc Desnoyers
CPC classification number: C07K16/40 , A61K31/138 , A61K31/4196 , A61K31/4745 , A61K31/475 , A61K31/506 , A61K31/517 , A61K31/565 , A61K31/5685 , A61K38/17 , A61K39/3955 , A61K45/06 , A61K2039/505 , C07K14/71 , C07K2317/31 , C07K2317/33 , C07K2317/75 , C07K2317/76 , G01N33/5032 , G01N33/57438 , G01N33/57492 , G01N33/74 , G01N2333/50 , G01N2333/705 , G01N2333/71 , G01N2500/02 , G01N2500/04 , G01N2500/10 , A61K2300/00
Abstract: The invention concerns uses of anti-KLβ agents, and detection of KLβ and/or FGF19 and/or FGFR4.
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公开(公告)号:US20030068708A1
公开(公告)日:2003-04-10
申请号:US10196752
申请日:2002-07-16
Applicant: Genentech, Inc.
Inventor: Kevin P. Baker , Jian Chen , Luc Desnoyers , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , James Pan , Victoria Smith , Colin K. Watanabe , William I. Wood , Zemin Zhang
IPC: C12P021/02 , C12N005/06 , C07K014/435 , C07H021/04 , C12N009/00
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US20150368358A1
公开(公告)日:2015-12-24
申请号:US14670358
申请日:2015-03-26
Applicant: GENENTECH, INC.
Inventor: Luc Desnoyers
IPC: C07K16/40 , G01N33/574 , A61K45/06
CPC classification number: C07K16/40 , A61K31/138 , A61K31/4196 , A61K31/4745 , A61K31/475 , A61K31/506 , A61K31/517 , A61K31/565 , A61K31/5685 , A61K38/17 , A61K39/3955 , A61K45/06 , A61K2039/505 , C07K14/71 , C07K2317/31 , C07K2317/33 , C07K2317/75 , C07K2317/76 , G01N33/5032 , G01N33/57438 , G01N33/57492 , G01N33/74 , G01N2333/50 , G01N2333/705 , G01N2333/71 , G01N2500/02 , G01N2500/04 , G01N2500/10 , A61K2300/00
Abstract: The invention concerns uses of anti-KLβ agents, and detection of KLβ and/or FGF19 and/or FGFR4.
Abstract translation: 本发明涉及抗KL&bgr的用途; 代理商,检测KL&bgr; 和/或FGF19和/或FGFR4。
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公开(公告)号:US20140363435A1
公开(公告)日:2014-12-11
申请号:US14302895
申请日:2014-06-12
Applicant: GENENTECH, INC.
Inventor: Luc Desnoyers
IPC: C07K16/40
CPC classification number: C07K16/40 , A61K31/138 , A61K31/4196 , A61K31/4745 , A61K31/475 , A61K31/506 , A61K31/517 , A61K31/565 , A61K31/5685 , A61K38/17 , A61K39/3955 , A61K45/06 , A61K2039/505 , C07K14/71 , C07K2317/31 , C07K2317/33 , C07K2317/75 , C07K2317/76 , G01N33/5032 , G01N33/57438 , G01N33/57492 , G01N33/74 , G01N2333/50 , G01N2333/705 , G01N2333/71 , G01N2500/02 , G01N2500/04 , G01N2500/10 , A61K2300/00
Abstract: The invention concerns uses of anti-KLβ agents, and detection of KLβ and/or FGF19 and/or FGFR4.
Abstract translation: 本发明涉及抗KL&bgr的用途; 代理商,检测KL&bgr; 和/或FGF19和/或FGFR4。
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公开(公告)号:US20220089780A1
公开(公告)日:2022-03-24
申请号:US17411753
申请日:2021-08-25
Applicant: Genentech, Inc.
Inventor: Luc Desnoyers
IPC: C07K16/40 , G01N33/50 , A61K31/506 , A61K31/475 , A61K31/4196 , A61K31/138 , A61K31/565 , A61K31/4745 , A61K31/517 , A61K31/5685 , A61K38/17 , G01N33/74 , A61K39/395 , A61K45/06 , C07K14/71 , G01N33/574
Abstract: The invention concerns uses of anti-KLβ agents, and detection of KLβ and/or FGF19 and/or FGFR4.
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公开(公告)号:US09266955B2
公开(公告)日:2016-02-23
申请号:US14046659
申请日:2013-10-04
Applicant: Genentech, Inc.
Inventor: Mark Dennis , Luc Desnoyers , Dorothy French
IPC: A61K39/395 , C07K16/00 , C07K16/28 , A61K45/06 , A61K39/00
CPC classification number: C07K16/2863 , A61K39/3955 , A61K45/06 , A61K2039/505 , C07K2317/24 , C07K2317/33 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/734 , C07K2317/76 , C07K2317/92 , C07K2317/94
Abstract: The invention provides anti-FGFR4 antibodies and methods of using the same.
Abstract translation: 本发明提供抗FGFR4抗体及其使用方法。
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公开(公告)号:US20150132309A1
公开(公告)日:2015-05-14
申请号:US14579054
申请日:2014-12-22
Applicant: Genentech, Inc.
Inventor: Luc Desnoyers
IPC: C07K14/71 , G01N33/74 , G01N33/574 , A61K39/395 , A61K45/06
CPC classification number: C07K16/40 , A61K31/138 , A61K31/4196 , A61K31/4745 , A61K31/475 , A61K31/506 , A61K31/517 , A61K31/565 , A61K31/5685 , A61K38/17 , A61K39/3955 , A61K45/06 , A61K2039/505 , C07K14/71 , C07K2317/31 , C07K2317/33 , C07K2317/75 , C07K2317/76 , G01N33/5032 , G01N33/57438 , G01N33/57492 , G01N33/74 , G01N2333/50 , G01N2333/705 , G01N2333/71 , G01N2500/02 , G01N2500/04 , G01N2500/10 , A61K2300/00
Abstract: The invention concerns uses of anti-KLβ agents, and detection of KLβ and/or FGF19 and/or FGFR4.
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