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公开(公告)号：US20190153517A1
公开(公告)日：2019-05-23
申请号：US16261532
申请日：2019-01-29
Applicant: General Electric Company
Inventor： Bing Li , David Roger Moore , William Christopher Alberts , John Richard Nelson
IPC: C12Q1/6806 , G01N33/543
Abstract: An electrospinning approach is disclosed for generating a dissolvable formulation of a reagent of interest in a nanoscale fiber medium. In one embodiment, the nanoscale fibers can incorporate and stabilize biological agents of interest, such as for storage at room temperature for extended periods. In one implementation, the fibers can be produced in a continuous manner and dissolve rapidly.
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Patent Agency Ranking
公开(公告)号：US20160146795A1
公开(公告)日：2016-05-26
申请号：US14548338
申请日：2014-11-20
Applicant: General Electric Company
Inventor： Bing Li , Brian Christopher Bales , David Roger Moore , Jason Michael Nichols , Cathryn Ellen Olsen , William Christopher Alberts , Frank John Mondello
IPC: G01N33/548
CPC classification number: G01N33/548 , B01D67/009 , B01D69/144 , B01D71/78 , G01N33/54353 , Y02A50/57
Abstract: A modified porous membrane comprising a polymer coating grafted to a porous membrane is described. A method for analyte detection from a biological sample using an immunoassay is also provided using the modified membrane, wherein the method comprises a) providing a modified porous membrane having the structure of Formula (I), b) incubating the modified porous membrane with a first biomolecule, wherein the first biomolecule binds to the modified porous membrane to form a first biomolecule bound modified porous membrane; and c) adding a biological sample comprising at least an analyte to the first biomolecule bound modified porous membrane for analyte detection by binding the analyte to the first biomolecule bound to the modified porous membrane.
Abstract translation: 描述了包含接枝到多孔膜上的聚合物涂层的改性多孔膜。 还提供了使用免疫测定法从生物样品中分析物检测的方法，其中所述方法包括：a）提供具有式（I）结构的改性多孔膜，b）将所述改性多孔膜与第一 生物分子，其中所述第一生物分子与修饰的多孔膜结合以形成第一生物分子结合的改性多孔膜; 和c）将包含至少一种分析物的生物样品添加到第一生物分子结合的改性多孔膜上，以通过将分析物结合到与修饰的多孔膜结合的第一生物分子来进行分析物检测。
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公开(公告)号：US20150176056A1
公开(公告)日：2015-06-25
申请号：US14140127
申请日：2013-12-24
Applicant: General Electric Company
Inventor： Bing Li , David Roger Moore , William Christopher Alberts , John Richard Nelson
IPC: C12Q1/68 , G01N33/543
CPC classification number: C12Q1/6806 , G01N33/54346 , G01N33/54393
Abstract: An electrospinning approach is disclosed for generating a dissolvable formulation of a reagent of interest in a nanoscale fiber medium. In one embodiment, the nanoscale fibers can incorporate and stabilize biological agents of interest, such as for storage at room temperature for extended periods. In one implementation, the fibers can be produced in a continuous manner and dissolve rapidly.
Abstract translation: 公开了一种静电纺丝方法，用于在纳米级纤维介质中产生感兴趣的试剂的可溶性制剂。 在一个实施方案中，纳米级纤维可以掺入并稳定感兴趣的生物试剂，例如在室温下长时间储存。 在一个实施方案中，纤维可以以连续的方式生产并迅速溶解。
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公开(公告)号：US10202636B2
公开(公告)日：2019-02-12
申请号：US14140127
申请日：2013-12-24
Applicant: General Electric Company
Inventor： Bing Li , David Roger Moore , William Christopher Alberts , John Richard Nelson
IPC: C12Q1/68 , C12Q1/6806 , G01N33/543
Abstract: An electrospinning approach is disclosed for generating a dissolvable formulation of a reagent of interest in a nanoscale fiber medium. In one embodiment, the nanoscale fibers can incorporate and stabilize biological agents of interest, such as for storage at room temperature for extended periods. In one implementation, the fibers can be produced in a continuous manner and dissolve rapidly.
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公开(公告)号：US20160146802A1
公开(公告)日：2016-05-26
申请号：US14548383
申请日：2014-11-20
Applicant: General Electric Company
Inventor： Bing Li , Brian Christopher Bales , David Roger Moore , Jason Michael Nichols , Cathryn Ellen Olsen , William Christopher Alberts , Frank John Mondello
IPC: G01N33/543 , G01N33/548 , G01N33/558
CPC classification number: G01N33/54386 , G01N33/54353 , G01N33/548 , G01N33/558
Abstract: A device comprising a modified porous membrane is provided. The modified porous membrane comprises a polymer coating grafted to a porous membrane. The device is used for analyte detection from a biological sample using an immunoassay. The device comprises a sample application zone at one end of the device for applying a biological sample comprising a target analyte; and a detection zone present at another end of the device, downstream of the sample application zone for detecting the target analyte, wherein the detection zone comprises one or more first biomolecules immobilized on a modified porous membrane having a structure of Formula (I).
Abstract translation: 提供了包含改性多孔膜的装置。 改性多孔膜包括接枝到多孔膜上的聚合物涂层。 该装置用于使用免疫测定从生物样品进行分析物检测。 该装置包括用于施加包含目标分析物的生物样品的装置的一端处的样品施加区域; 以及位于所述装置的另一端的检测区，其位于所述样品施加区的下游，用于检测所述目标分析物，其中所述检测区包含固定在具有式（I）的结构的改性多孔膜上的一个或多个第一生物分子。
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公开(公告)号：US20240082815A1
公开(公告)日：2024-03-14
申请号：US17932158
申请日：2022-09-14
Applicant: General Electric Company
Inventor： Michael Joseph O'Brien , David Roger Moore , William Christopher Alberts , Jingjing Yang , Mark Daniel Doherty , Mark D. Buckley , Jack E. Howson , Bryce E. Lipinski
CPC classification number: B01J20/226 , B01D53/02 , B01D53/261 , B01J20/261 , B01J20/262 , B01J20/267 , B01J20/2803 , B01J20/3223 , B01J20/3225 , B01J20/3265 , B01D2253/204 , B01D2257/302 , B01D2257/504 , B01D2257/80
Abstract: In some embodiments, the present disclosure relates to a system. The system includes a substrate and a fluid capture material formed on one or more surfaces of the substrate. The fluid capture material includes a sorbent material that binds one or more fluids, the one or more fluids comprising water, carbon dioxide, sulfur oxides, or a combination thereof. The fluid capture material also includes one or more binder materials, wherein the binder material is at least partially cross-linked.
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