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公开(公告)号：US07862496B2
公开(公告)日：2011-01-04
申请号：US11276851
申请日：2006-03-16
申请人： George D. Hermann , Eduardo Chi Sing , Gail S. Lebovic , Mark A. Cole , Mark A. Ritchart , Than Nguyen
发明人： George D. Hermann , Eduardo Chi Sing , Gail S. Lebovic , Mark A. Cole , Mark A. Ritchart , Than Nguyen
IPC分类号： A61N5/00
CPC分类号： A61N5/1015 , A61N2005/1018
摘要： Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways.
摘要翻译： 用于将近距离放射治疗递送到目标组织区域的装置包括细长主体，其包括近端，远端，其尺寸适于引入到组织道中并且承载多个细长构件，包括用于接收辐射源的路径。 细长构件可在折叠和膨胀构型之间移动。 在使用期间，通过组织产生管道，并且携带细长构件的细长体通过管道前进到目标位置，细长构件处于收缩构型。 细长构件在目标位置处被引导到扩展构型，并且例如通过沿着路径引入一个或多个辐射源，传送辐射以在目标位置处理组织。
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公开(公告)号：US10201716B2
公开(公告)日：2019-02-12
申请号：US12982823
申请日：2010-12-30
申请人： George D. Hermann , Eduardo Chi Sing , Gail S. Lebovic , Mark A. Cole , Mark A. Ritchart , Than Nguyen
发明人： George D. Hermann , Eduardo Chi Sing , Gail S. Lebovic , Mark A. Cole , Mark A. Ritchart , Than Nguyen
摘要： Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways.
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公开(公告)号：US20100204537A1
公开(公告)日：2010-08-12
申请号：US12764892
申请日：2010-04-21
申请人： George D. Hermann , Eduardo Chi Sing , Gail S. Lebovic , Mark A. Cole , Mark A. Ritchart , Than Nguyen
发明人： George D. Hermann , Eduardo Chi Sing , Gail S. Lebovic , Mark A. Cole , Mark A. Ritchart , Than Nguyen
IPC分类号： A61M36/12
CPC分类号： A61N5/1015 , A61N2005/1018
摘要： Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways.
摘要翻译： 用于将近距离放射治疗递送到目标组织区域的装置包括细长主体，其包括近端，远端，其尺寸适于引入到组织道中并且承载多个细长构件，包括用于接收辐射源的路径。 细长构件可在折叠和膨胀构型之间移动。 在使用期间，通过组织产生管道，并且携带细长构件的细长体通过管道前进到目标位置，细长构件处于收缩构型。 细长构件在目标位置处被引导到扩展构型，并且例如通过沿着路径引入一个或多个辐射源，传送辐射以在目标位置处理组织。
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公开(公告)号：US20110137103A1
公开(公告)日：2011-06-09
申请号：US12982823
申请日：2010-12-30
申请人： George D. Hermann , Eduardo Chi Sing , Gail S. Lebovic , Mark A. Cole , Mark A. Ritchart , Than Nguyen
发明人： George D. Hermann , Eduardo Chi Sing , Gail S. Lebovic , Mark A. Cole , Mark A. Ritchart , Than Nguyen
IPC分类号： A61M36/12
CPC分类号： A61N5/1015 , A61N2005/1018
摘要： Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways.
摘要翻译： 用于将近距离放射治疗递送到目标组织区域的装置包括细长主体，其包括近端，远端，其尺寸适于引入到组织道中并且承载多个细长构件，包括用于接收辐射源的路径。 细长构件可在折叠和膨胀构型之间移动。 在使用期间，通过组织产生管道，并且携带细长构件的细长体通过管道前进到目标位置，细长构件处于收缩构型。 细长构件在目标位置处被引导到扩展构型，并且例如通过沿着路径引入一个或多个辐射源，传送辐射以在目标位置处理组织。
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公开(公告)号：US07887476B2
公开(公告)日：2011-02-15
申请号：US11557747
申请日：2006-11-08
IPC分类号： A61N5/00
CPC分类号： A61N5/1015 , A61N5/1027 , A61N2005/1018
摘要： Apparatus, systems, and methods are provided for delivering brachytherapy into a target tissue region, e.g., a breast. In some embodiments, a flexible brachytherapy device is implanted that includes a therapy delivery portion having one or more radioactive sources securely retained thereto, and a tail portion extending from the therapy delivery portion. The brachytherapy device may be implanted in a helical configuration within the target tissue region. To assist in placement and removal of the brachytherapy device, a tubular sheath may be implanted by attaching (e.g., sliding over) a helically coiled needle that is advanced into the body by screw-like rotation. Once implanted, the sheath and the brachytherapy device may extend outside the body, where they may be folded and secured flat against the skin. The device and sheath may be removed at therapy completion.
摘要翻译： 提供装置，系统和方法用于将近距离放射治疗递送到目标组织区域，例如乳房。 在一些实施例中，植入柔性近距离放射治疗装置，其包括具有一个或多个可靠地保持在其上的放射源的治疗递送部分和从治疗递送部分延伸的尾部。 近程放射治疗装置可以以目标组织区域内的螺旋形构造植入。 为了帮助放置和去除近距离放射治疗装置，可以通过螺旋状旋转将附着（例如，滑过）螺旋卷绕的针头注入身体来植入管状护套。 一旦植入，护套和近距离放射治疗装置可以延伸到身体外部，在那里它们可以被折叠并且平坦地固定在皮肤上。 在治疗完成时可以移除装置和护套。
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公开(公告)号：US09072893B2
公开(公告)日：2015-07-07
申请号：US11757231
申请日：2007-06-01
申请人： Eduardo Chi Sing , George D. Hermann , Dong S. Sutton , Tommy G. Nguyen , Mark A. Ritchart , Steven L. Gex
发明人： Eduardo Chi Sing , George D. Hermann , Dong S. Sutton , Tommy G. Nguyen , Mark A. Ritchart , Steven L. Gex
CPC分类号： A61N5/1015 , A61N2005/1018
摘要： Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways.
摘要翻译： 用于将近距离放射治疗递送到目标组织区域的装置包括细长主体，其包括近端，远端，其尺寸适于引入到组织道中并且承载多个细长构件，包括用于接收辐射源的路径。 细长构件可在折叠和膨胀构型之间移动。 在使用期间，通过组织产生管道，并且携带细长构件的细长体通过管道前进到目标位置，细长构件处于收缩构型。 细长构件在目标位置处被引导到扩展构型，并且例如通过沿着路径引入一个或多个辐射源，传送辐射以在目标位置处理组织。
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公开(公告)号：US20080221384A1
公开(公告)日：2008-09-11
申请号：US11757231
申请日：2007-06-01
申请人： Eduardo Chi Sing , George D. Hermann , Doug S. Sutton , Tommy G. Nguyen , Mark A. Ritchart , Steven L. Gex
发明人： Eduardo Chi Sing , George D. Hermann , Doug S. Sutton , Tommy G. Nguyen , Mark A. Ritchart , Steven L. Gex
CPC分类号： A61N5/1015 , A61N2005/1018
摘要： Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways.
摘要翻译： 用于将近距离放射治疗递送到目标组织区域的装置包括细长主体，其包括近端，远端，其尺寸适于引入到组织道中并且承载多个细长构件，包括用于接收辐射源的路径。 细长构件可在折叠和膨胀构型之间移动。 在使用期间，通过组织产生管道，并且携带细长构件的细长体通过管道前进到目标位置，细长构件处于收缩构型。 细长构件在目标位置处被引导到扩展构型，并且例如通过沿着路径引入一个或多个辐射源，传送辐射以在目标位置处理组织。
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8.发明授权公开(公告)号：US09452015B2
公开(公告)日：2016-09-27
申请号：US13161356
申请日：2011-06-15
申请人： Brad M. Kellerman , David Trottingwolf Aldridge , David K. Wrolstad , Mark A. Ritchart , Jeffrey E. Hull
发明人： Brad M. Kellerman , David Trottingwolf Aldridge , David K. Wrolstad , Mark A. Ritchart , Jeffrey E. Hull
CPC分类号： A61B18/1492 , A61B17/11 , A61B17/320068 , A61B18/08 , A61B18/082 , A61B18/18 , A61B18/24 , A61B2017/1107 , A61B2017/1139 , A61B2018/00386 , A61B2018/00404 , A61B2018/00422 , A61B2018/00595 , A61B2018/00601 , A61B2018/00619 , A61B2018/00714 , A61B2018/1475
摘要： A device for creating an arteriovenous (AV) fistula comprises an elongate member, a distal member connected to the elongate member and movable relative to the elongate member, and a heating member disposed on at least one of the movable distal member and the elongate member. The distal member comprises structure for capturing tissue to be cut to create the fistula, and the heating member is adapted to cut through the tissue to create the fistula. The elongate member comprises an elongate outer tube. A shaft connects the distal member to the elongate member, and is extendable and retractable to extend and retract the distal member relative to the elongate member.
摘要翻译： 用于产生动静脉（AV）瘘的装置包括细长构件，连接到细长构件并且可相对于细长构件移动的远端构件，以及设置在可移动远端构件和细长构件中的至少一个上的加热构件。 远侧构件包括用于捕获要切割的组织以产生瘘的结构，并且加热构件适于切穿组织以产生瘘。 细长构件包括细长的外管。 轴将远端构件连接到细长构件，并且可延伸和缩回以相对于细长构件延伸和缩回远侧构件。
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公开(公告)号：US09216069B2
公开(公告)日：2015-12-22
申请号：US12625112
申请日：2009-11-24
CPC分类号： A61B19/54 , A61B10/0275 , A61B10/0283 , A61B90/39 , A61B2017/00004 , A61B2090/3908 , A61B2090/3987 , Y10T24/4501
摘要： In order to later identify the location of a biopsy or surgery, various means and methods for permanently and non-surgically marking selected tissue in the human body are used. Later visualization of the markers is readily accomplished using state-of-the-art imaging systems.
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10.发明申请公开(公告)号：US20080154151A1
公开(公告)日：2008-06-26
申请号：US11931411
申请日：2007-10-31
IPC分类号： A61B10/04
CPC分类号： A61B10/0266 , A61B6/12 , A61B8/0841 , A61B10/0275 , A61B10/0283 , A61B17/221 , A61B2010/0208 , A61B2010/0225 , A61B2017/303
摘要： Instruments for performing percutaneous biopsy procedures are disclosed, which have advantageous features for improving functionality and performance over prior art devices. These instruments comprise two types, single-use devices, and multiple-use devices having active tissue capture capability. Improved features include the ability to retrieve and evaluate multiple tissue samples during a single insertion procedure, without physical handling of the samples, as well as constructional features, such as a molded tissue cassette housing, variant vacuum port embodiments suited for different tissue environments, and a method for backflushing the instrument to remove biological debris, among others.
摘要翻译： 公开了用于执行经皮活检程序的仪器，其具有改善现有技术装置的功能和性能的有利特征。 这些仪器包括两种类型的一次性装置，以及具有活跃组织捕获能力的多用途装置。 改进的特征包括在单次插入过程中检索和评估多个组织样本的能力，而不对样品进行物理处理，以及结构特征，例如模制的组织盒壳体，适合于不同组织环境的变体真空端口实施例，以及 一种反吹仪器以去除生物碎片的方法等。
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