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    Exhaust gas manifold
    1.
    再颁专利
    Exhaust gas manifold 失效
    排气歧管

    公开(公告)号：USRE28988E

    公开(公告)日：1976-10-05

    申请号：US452958

    申请日：1974-03-20

    申请人： George E. Scheitlin ,  David R. Bentley

    发明人： George E. Scheitlin ,  David R. Bentley

    IPC分类号： F01N3/26 ,  F01N13/10

    CPC分类号： F01N13/10 ,  F01N13/102 ,  F01N3/26

    摘要： An exhaust gas manifold for an internal combustion engine in which there is provided an outer shell including an outer sleeve having a pair of end caps closing the ends thereof. An inner shell is carried within the outer shell and is formed by a plurality of slidably interfit inner sleeves which are supported in spaced relation to the outer sleeve on mounting members mounted on a second pair of end caps closing the ends of said inner shell and connected to said first pair of end caps. A plurality of inlet conduits and an outlet conduit are connected to said outer shell, and a plurality of inlet conduits and an outlet conduit are also connected to said inner shell with the conduits on said inner shell being carried in, and movable with respect to, the conduits on said outer shell.

    Semaphorin-specific antibodies
    7.
    发明授权
    Semaphorin-specific antibodies 失效
    信号素特异性抗体

    公开(公告)号：US06344544B1

    公开(公告)日：2002-02-05

    申请号：US09060610

    申请日：1998-04-15

    申请人： Corey S. Goodman ,  Alex L. Kolodkin ,  David Matthes ,  David R. Bentley ,  Timothy O'Connor

    发明人： Corey S. Goodman ,  Alex L. Kolodkin ,  David Matthes ,  David R. Bentley ,  Timothy O'Connor

    IPC分类号： A61K39395

    CPC分类号： C12N15/8509 ,  A01K67/0339 ,  A01K2217/05 ,  A01K2217/075 ,  A01K2267/01 ,  A01K2267/03 ,  A01K2267/0318 ,  A61K38/00 ,  C07K14/005 ,  C07K14/4703 ,  C07K14/705 ,  C12N2710/24122

    摘要： A novel class of proteins, semaphorins, nucleic acids encoding semaphorins, semaphorin peptides, and methods of using semaphorins and semaphorin-encoding nucleic acids are disclosed. Semaphorin peptides and receptor agonists and antagonists provide potent modulators of nerve cell growth and regeneration. The invention provides pharmaceutical compositions, methods for screening chemical libraries for regulators of cell growth/differentiation; semaphorin gene-derived nucleic acids for use in genetic mapping, as probes for related genes, and as diagnostic reagents for genetic neurological disease; specific cellular and animal systems for the development of neurological disease therapy.

    摘要翻译： 公开了一类新颖的蛋白质，信号素，编码信号素的核酸，信号素肽，以及使用信号素和信号素编码核酸的方法。 信号肽和受体激动剂和拮抗剂提供神经细胞生长和再生的有效调节剂。 本发明提供药物组合物，用于筛选细胞生长/分化调节物的化学文库的方法; 用于遗传作图的信号素基因衍生的核酸，作为相关基因的探针，以及作为遗传神经疾病的诊断试剂; 特异性细胞和动物系统用于神经疾病治疗的发展。