3-hydroxy gamma-lactone based enantioselective synthesis of azetidinones
    2.
    发明授权
    3-hydroxy gamma-lactone based enantioselective synthesis of azetidinones 失效
    基于3-羟基γ-内酯的对映选择性合成氮杂环丁酮

    公开(公告)号:US5886171A

    公开(公告)日:1999-03-23

    申请号:US864529

    申请日:1997-05-28

    IPC分类号: C07D205/08

    CPC分类号: C07D205/08

    摘要: The invention relates to a process for producing a compound of the formula ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 are as defined in the specification, which comprises the steps of: (a) reacting a lactone with an imine to obtain a chiral diol of the formula IV; (b) oxidizing the diol to obtain an aldehyde of formula V; (c) condensing the aldehyde with an enolether followed by dehydration to obtain a compound of formula VI; (d) hydrogenating the compound of formula VI to obtain a ketone of formula VII; and (e) chirally catalytically reducing the ketone, wherein steps (b)-(d) are shown in the following reaction scheme: ##STR2##

    摘要翻译: 本发明涉及一种制备下式化合物的方法,其中R 1,R 2和R 3如说明书中所定义,其包括以下步骤:(a)使内酯与亚胺反应,得到手性二醇 公式IV; (b)氧化二醇以获得式V的醛; (c)将醛与烯醇缩合,然后脱水得到式VI化合物; (d)使式Ⅵ化合物氢化得到式Ⅶ的酮; 和(e)手性催化还原酮,其中步骤(b) - (d)显示在以下反应方案中:

    Synthesis of intermediates useful in preparing tricyclic compounds
    4.
    发明授权
    Synthesis of intermediates useful in preparing tricyclic compounds 失效
    可用于制备三环化合物的中间体的合成

    公开(公告)号:US5998620A

    公开(公告)日:1999-12-07

    申请号:US45803

    申请日:1998-03-23

    CPC分类号: C07D401/04 C07D221/16

    摘要: The invention relates to a process for preparing a compound of the formula ##STR1## comprising reacting a bromo-substituted pyridine with an amine of the formula NHR.sup.5 R.sup.6, reacting the resulting amide with an iodo-halomethyl-substituted compound and cyclizing the resultant product, wherein R, R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are as defined in the specification; also claimed are a compound of the formula ##STR2## and a process for preparing it from the corresponding halo-substituted benzoic acid.

    摘要翻译: 本发明涉及一种制备下式化合物的方法,其中包括使溴取代的吡啶与式NHR 5 R 6的胺反应,使得到的酰胺与碘代卤代甲基取代的化合物反应,并使得到的产物环化,其中R,R 1 R2,R3和R4如说明书中所定义; 还要求的是下式的化合物及其由相应的卤代取代的苯甲酸制备的方法。

    Synthesis of intermediates useful in preparing bromo-substituted
tricyclic compounds
    5.
    发明授权
    Synthesis of intermediates useful in preparing bromo-substituted tricyclic compounds 失效
    可用于制备溴代三环化合物的中间体的合成

    公开(公告)号:US5760232A

    公开(公告)日:1998-06-02

    申请号:US882753

    申请日:1997-06-16

    IPC分类号: C07D401/04 C07D221/16

    CPC分类号: C07D401/04

    摘要: The invention relates to a process for preparing a compound of the formula ##STR1## comprising: (a) reacting 2,5-dibromo-3-methylpyridine with an amine of the formula NHR.sup.5 R.sup.6 to obtain an amide; (b) reacting the amide with a compound of formula 3 ##STR2## in the presence of a strong base to obtain a compound of formula 4 ##STR3## (c) converting a compound of formula 4 to the corresponding cyano compound or aldehyde; (d) reacting the cyano compound or aldehyde with a piperidine derivative to obtain an aldehyde or alcohol of formula 7a or 7b, respectively: ##STR4## (e) cyclizing a compound of formula 7a or 7b; wherein R.sup.1 -R.sup.7 are as defined in the specification.

    摘要翻译: 本发明涉及制备式I化合物的方法,其包括:(a)使2,5-二溴-3-甲基吡啶与式NHR 5 R 6的胺反应,得到酰胺; (b)在强碱存在下使酰胺与式3化合物反应,得到式4化合物(c)将式4的化合物转化成相应的氰基化合物或醛 ; (d)使氰基化合物或醛与哌啶衍生物反应,分别得到式7a或7b的醛或醇:(e)使式7a或7b的化合物环化; 其中R1-R7如说明书中所定义。

    Inflatable game field system
    7.
    发明授权
    Inflatable game field system 有权
    充气游戏场系统

    公开(公告)号:US09149708B2

    公开(公告)日:2015-10-06

    申请号:US14116127

    申请日:2011-05-06

    申请人: Xing Chen

    发明人: Xing Chen

    摘要: An inflatable game field system includes at least two inflatable modules, at least one connecting pipeline and one air inlet system connected to blower(s). The inflatable modules are connected by the connecting pipeline, and the air inlet connects to one of the module at one end and connects to a blower at the other end, so that the air flow coming from the blower can move freely between the modules. This game field system can be setup in various locations, formed different field sizes and provide a safe game field.

    摘要翻译: 充气游戏场系统包括至少两个充气模块,至少一个连接管道和连接到鼓风机的一个空气入口系统。 充气模块通过连接管道连接,空气入口在一端连接到模块中的一个,并在另一端连接到鼓风机,使得来自鼓风机的空气流可在模块之间自由移动。 该游戏场系统可以在不同的位置进行设置,形成不同的场大小并提供安全的游戏场。

    Inflatable Game Field System
    8.
    发明申请
    Inflatable Game Field System 审中-公开
    充气游戏场系统

    公开(公告)号:US20140295980A1

    公开(公告)日:2014-10-02

    申请号:US14116127

    申请日:2011-05-06

    申请人: Xing Chen

    发明人: Xing Chen

    IPC分类号: A63B71/02

    摘要: An inflatable game field system includes at least two inflatable modules, at least one connecting pipeline and one air inlet system connected to blower(s). The inflatable modules are connected by the connecting pipeline, and the air inlet connects to one of the module at one end and connects to a blower at the other end, so that the air flow coming from the blower can move freely between the modules. This game field system can be setup in various locations, formed different field sizes and provide a safe game field.

    摘要翻译: 充气游戏场系统包括至少两个充气模块,至少一个连接管道和连接到鼓风机的一个空气入口系统。 充气模块通过连接管道连接,空气入口在一端连接到模块中的一个,并在另一端连接到鼓风机,使得来自鼓风机的空气流可在模块之间自由移动。 该游戏场系统可以在不同的位置进行设置,形成不同的场大小并提供安全的游戏场。