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    Fiber tracking phantom
    2.
    发明授权
    Fiber tracking phantom 有权
    光纤追踪幻影

    公开(公告)号：US07521931B2

    公开(公告)日：2009-04-21

    申请号：US11318346

    申请日：2005-12-23

    申请人： George Ogrezeanu ,  Andreas Hartlep

    发明人： George Ogrezeanu ,  Andreas Hartlep

    IPC分类号： G01V3/00

    CPC分类号： A61B6/583 ,  A61B5/055 ,  A61B5/7207 ,  A61B2560/0228 ,  G01R33/56341 ,  G01R33/58

    摘要： A phantom for use with diffusion tensor imaging includes a container and a plurality of structures within the container. The structures have anisotropic properties, wherein when the phantom is subjected to diffusion tensor imaging, the structures provide data that is recognized as fiber bundles. The structures can be formed, for example, from cloth tape, silk, wood, glass fibers cord (synthetic and viscose) and/or microfibers.

    摘要翻译： 用于扩散张量成像的体模包括容器和容器内的多个结构。 该结构具有各向异性特性，其中当体模经受扩散张量成像时，该结构提供被认为是纤维束的数据。 结构可以例如由布带，丝绸，木材，玻璃纤维帘线（合成和粘胶）和/或微纤维形成。

    INTRACRANIAL CATHETER
    4.
    发明申请
    INTRACRANIAL CATHETER 有权

    公开(公告)号：US20110066133A1

    公开(公告)日：2011-03-17

    申请号：US12950223

    申请日：2010-11-19

    申请人： Andreas Hartlep ,  Christoph Pedain

    发明人： Andreas Hartlep ,  Christoph Pedain

    IPC分类号： A61M25/14

    CPC分类号： A61M25/007 ,  A61M25/0009 ,  A61M25/0021 ,  A61M2025/006

    摘要： A catheter having an outer profile which is formed such that a path length along an outer surface of the catheter is greater than the corresponding length of the catheter, and to a method for determining the shape of a catheter, and wherein the elasticity and/or conductivity of the tissue into which the catheter is to be introduced is taken into account in order to determine the outer profile of the catheter.

    摘要翻译： 一种具有外形轮廓的导管，其形成为使得沿着导管的外表面的路径长度大于导管的相应长度，以及用于确定导管形状的方法，并且其中弹性和/或 考虑到要导入导管的组织的导电性，以便确定导管的外部轮廓。

    Catheter with portions that can change in volume
    5.
    发明授权
    Catheter with portions that can change in volume 有权
    导管与部分可以改变体积

    公开(公告)号：US07883492B2

    公开(公告)日：2011-02-08

    申请号：US12049534

    申请日：2008-03-17

    申请人： Stephan Mittermeyer ,  Andreas Hartlep

    发明人： Stephan Mittermeyer ,  Andreas Hartlep

    IPC分类号： A61M29/00

    CPC分类号： A61M25/0023 ,  A61M25/0045 ,  A61M2005/14292 ,  A61M2025/0057 ,  A61M2025/006 ,  A61M2025/1052

    摘要： A catheter for administering a substance into body tissues includes an elongated catheter body that has at least one portion of the length of the catheter body that expands after the catheter is inserted in the patient's body. The portion that expands provides a seal against backflow of the substance along the outer surface of the catheter body and away from the intended treatment area.

    摘要翻译： 用于将物质施用到身体组织中的导管包括细长的导管体，其具有导管主体的长度的至少一部分，其在将导管插入患者体内后扩张。 膨胀的部分提供密封，以防止物质沿着导管主体的外表面并远离预期治疗区域的回流。

    Targeted infusion of agents for treatment of ALS
    7.
    发明申请
    Targeted infusion of agents for treatment of ALS 有权
    靶向输注用于治疗ALS的药剂

    公开(公告)号：US20060094953A1

    公开(公告)日：2006-05-04

    申请号：US11251548

    申请日：2005-10-14

    申请人： Andreas Hartlep ,  Christoph Pedain

    发明人： Andreas Hartlep ,  Christoph Pedain

    IPC分类号： A61B5/05

    CPC分类号： A61B90/36 ,  A61B5/0478 ,  A61B5/055 ,  A61B5/4839 ,  A61B34/10 ,  A61B34/20 ,  A61B2017/00039 ,  A61B2034/2055

    摘要： A system and method for treating Amyotrophic Lateral Sclerosis (ALS) by delivery of an agent within the brain. At least one image of a target region is acquired, and at least one magnetic resonance diffusion tensor imaging (MR-DTI) scan of the target region is acquired. A diffusion tensor is calculated from the at least one MR-DTI scan, and at least one of an agent distribution and an agent concentration from the images and the calculated diffusion tensor is calculated. Using at least one of the calculated diffusion tensor, the images, the calculated agent distribution, and the calculated agent concentration, the placement of a delivery instrument is planned to deliver the agent to the target region to achieve a desired agent concentration and/or agent distribution within the target region.

    摘要翻译： 一种通过在脑内递送药物来治疗肌萎缩性侧索硬化症（ALS）的系统和方法。 获取目标区域的至少一个图像，并且获取目标区域的至少一个磁共振扩散张量成像（MR-DTI）扫描。 从至少一个MR-DTI扫描计算扩散张量，并且计算来自图像和所计算的扩散张量的试剂分布和试剂浓度中的至少一个。 使用所计算的扩散张量，图像，计算的药物分布和计算的药物浓度中的至少一个，计划递送仪器的放置以将药剂递送至靶区域以实现所需药剂浓度和/或药剂 分布在目标区域内。

    Method and device for assisting in a tissue treatment
    8.
    发明授权
    Method and device for assisting in a tissue treatment 有权
    用于辅助组织处理的方法和装置

    公开(公告)号：US08702580B2

    公开(公告)日：2014-04-22

    申请号：US11244867

    申请日：2005-10-06

    申请人： Andreas Hartlep ,  Christoph Pedain

    发明人： Andreas Hartlep ,  Christoph Pedain

    IPC分类号： A61M3/00

    CPC分类号： G16H50/50 ,  G06F19/00

    摘要： A method for planning to treat tissue by administering a substance which emits energy or can interact with administered energy to a body, such as body tissue, wherein a dispersion of the substance in the body is simulated, and to a system or device for planning administering a substance and administering energy to a body or in body tissue. The device includes a data capture unit configured to detect patient-specific parameters, wherein the patient-specific parameters can be used to describe a dispersion behavior of the substance in the body or body tissue; a computational unit operatively coupled to the data capture unit, said computational unit configured to obtain the patient-specific parameters from the data capture unit; a database accessible by the computational unit, wherein the database includes data for describing characteristics of a particular type of tissue or a particular body structure, data for describing mechanisms for supplying energy, and/or data for describing the effect on tissue of a substance in combination with supplied energy, the computational unit being configured to retrieve and/or store said data in the database; and an input unit via which a user can input treatment-specific data to the computational unit, wherein the computational unit is configured to simulate the plan based on at least one of the patient-specific data, data stored in the database, or user input data.

    摘要翻译： 一种用于通过施用发射能量或可以与施用的能量相互作用的物质来计划治疗组织的方法，所述身体例如身体组织，其中物质在体内的分散体被模拟，并且用于规划管理 物质并向体内或身体组织施用能量。 该装置包括被配置为检测患者特异性参数的数据捕获单元，其中可以使用患者特异性参数来描述物质在体内或身体组织中的分散行为; 计算单元，可操作地耦合到所述数据捕获单元，所述计算单元被配置为从所述数据捕获单元获取患者特定参数; 由计算单元访问的数据库，其中数据库包括用于描述特定类型的组织或特定身体结构的特征的数据，用于描述用于供应能量的机制的数据和/或用于描述对物质组织的影响的数据 与所提供的能量组合，所述计算单元被配置为在所述数据库中检索和/或存储所述数据; 以及输入单元，用户可以通过该单元将计算单元输入治疗特定数据，其中所述计算单元被配置为基于所述患者特定数据，存储在所述数据库中的数据或用户输入中的至少一个来模拟所述计划 数据。

    Method and device for preparing a drainage
    10.
    发明授权
    Method and device for preparing a drainage 有权
    排水方法及装置

    公开(公告)号：US07734326B2

    公开(公告)日：2010-06-08

    申请号：US10464057

    申请日：2003-06-18

    申请人： Christoph Pedain ,  Andreas Hartlep

    发明人： Christoph Pedain ,  Andreas Hartlep

    IPC分类号： A61B5/05

    CPC分类号： A61M1/0058 ,  A61B34/10 ,  A61B34/20 ,  A61B34/25 ,  A61B90/36 ,  A61B2034/2055 ,  A61B2034/252 ,  A61M2005/14292

    摘要： A method for positioning at least one catheter on a body in which a fluid is present includes performing a body-specific detection of anatomical structure and/or tissue structure. A position of the fluid in the body and/or the amount of fluid in the body are detected and at least one catheter is positioned such that at least a part of the fluid can be drained from the body. A method for simulating drainage of a fluid from an interstice of a body includes performing a body-specific detection of anatomical structure and/or tissue structure. A position of the fluid in the body and/or the amount of fluid in the body are detected and a location of at least one catheter on the body is set.

    摘要翻译： 用于将至少一个导管定位在其中存在流体的身体上的方法包括执行解剖结构和/或组织结构的身体特异性检测。 检测体内流体的位置和/或体内的流体量，并且至少一个导管被定位成使得至少一部分流体可以从身体排出。 用于模拟来自身体的空隙的流体的排水的方法包括执行解剖结构和/或组织结构的身体特异性检测。 检测身体中流体的位置和/或体内的流体量，并且设置身体上至少一个导管的位置。