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1.发明授权Apparatus and process for strengthening low density compression dosage units and product therefrom 失效用于加强低密度压缩剂量单位及其产品的装置和方法
公开(公告)号：US5728400A
公开(公告)日：1998-03-17
申请号：US743221
申请日：1996-11-05
IPC分类号： A61J3/06 , A23G3/00 , A23G3/10 , A23G3/36 , A61J3/10 , A61K9/00 , A61K9/20 , A61K9/22 , A61K9/70 , B30B11/02 , A61K9/46
CPC分类号： A23G3/10 , A23G3/368 , A61J3/10 , A61K9/0056 , A61K9/2018 , A61K9/2095 , A61K9/70 , B30B11/027
摘要： The present invention is a process for forming a low density compression dosage unit to provide increased strength. The process of the present invention includes compacting under bi-level compaction pressure to provide a continuous-volume dosage unit which has a first volume defining an edge portion of the unit and a density which is greater than a density of a second volume defining a non-edge portion of the unit. The present invention also includes the product resulting from the process and apparatus used to make such units.
摘要翻译： 本发明是形成低密度压缩剂量单位以提高强度的方法。 本发明的方法包括在双层压实压力下进行压实以提供连续体积剂量单位，其具有限定单元的边缘部分的第一体积，并且密度大于限定非水平的第二体积的密度 - 部分的单位。 本发明还包括由用于制造这种单元的方法和装置产生的产品。
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2.发明授权Apparatus and process for strengthening low density compression dosage units and product therefrom 失效用于加强低密度压缩剂量单位及其产品的装置和方法
公开(公告)号：US5616344A
公开(公告)日：1997-04-01
申请号：US276244
申请日：1994-07-18
IPC分类号： A61J3/06 , A23G3/00 , A23G3/10 , A23G3/36 , A61J3/10 , A61K9/00 , A61K9/20 , A61K9/22 , A61K9/70 , B30B11/02
CPC分类号： A23G3/10 , A23G3/368 , A61J3/10 , A61K9/0056 , A61K9/2018 , A61K9/2095 , A61K9/70 , B30B11/027
摘要： The present invention is a process for forming a low density compression dosage unit to provide increased strength. The process of the present invention includes compacting under bi-level compaction pressure to provide a continuous-volume dosage unit which has a first volume defining an edge portion of the unit and a density which is greater than a density of a second volume defining a non-edge portion of the unit. The present invention also includes the product resulting from the process and apparatus used to make such units.
摘要翻译： 本发明是形成低密度压缩剂量单位以提高强度的方法。 本发明的方法包括在双层压实压力下进行压实以提供连续体积剂量单位，其具有限定单元的边缘部分的第一体积，并且密度大于限定非水平的第二体积的密度 - 部分的单位。 本发明还包括由用于制造这种单元的方法和装置产生的产品。
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公开(公告)号：US5866188A
公开(公告)日：1999-02-02
申请号：US982128
申请日：1997-12-01
IPC分类号： A21D15/08 , A23G3/00 , A23G3/10 , A23G3/34 , A23G3/36 , A61K9/00 , A61K9/20 , A61K9/70 , C13B30/02 , C13B50/00 , C13K1/10 , C13K13/00 , C13F1/02 , C13F3/00 , A21O13/00 , A21O13/08
CPC分类号： A23G3/368 , A23G3/10 , A23G3/346 , A61K9/2018 , A61K9/2095 , A61K9/70 , C13B30/021 , C13B50/00 , A23G2200/06 , A61K9/0056
摘要： The present invention is a comestible composition including a new spheroidal polycrystallite product. In the present invention amorphous sugar is transformed to crystalline sugar by hydrating rather than dehydrating sugar.
摘要翻译： 本发明是包含新型球状多晶产品的食品组合物。 在本发明中，无定形糖通过水合而不是脱水糖转化成结晶糖。
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公开(公告)号：US5851553A
公开(公告)日：1998-12-22
申请号：US772024
申请日：1996-12-19
IPC分类号： A23G3/00 , A23G3/10 , A23G3/34 , A23G3/36 , A61K9/00 , A61K9/20 , A61K9/70 , C13B30/02 , A61K9/22
CPC分类号： A23G3/10 , A23G3/346 , A23G3/368 , A61K9/0056 , A61K9/2018 , A61K9/2095 , A61K9/70 , C13B30/021 , C13B50/00 , A23G2200/06 , A61F2013/0296 , Y10S514/96
摘要： The present invention is a method of preparing rapidly dissolving comestible units such as tablets. The present invention also includes an apparatus for making the comestible units and the units themselves. The product prepared in accordance with the present invention can include active ingredients and is capable of dissolving in the mouth of the consumer within several seconds. The unit dosage forms prepared in accordance with the present invention are particularly useful as antacids and as a delivery vehicle for biologically active ingredients, especially those which are ideally combined with antacid ingredients in order to ameliorate the effects of antacid environment.
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公开(公告)号：US5871781A
公开(公告)日：1999-02-16
申请号：US772022
申请日：1996-12-19
IPC分类号： A23G3/00 , A23G3/10 , A23G3/34 , A23G3/36 , A61K9/00 , A61K9/20 , A61K9/70 , C13B30/02 , C13B50/00 , B29C43/00
CPC分类号： A23G3/368 , A23G3/10 , A23G3/346 , A61K9/0056 , A61K9/2018 , A61K9/2095 , A61K9/70 , C13B30/021 , C13B50/00 , A23G2200/06 , A61F2013/0296 , Y10S514/819 , Y10S514/948 , Y10S514/96 , Y10S514/965
摘要： The present invention involves an apparatus for making comestible units. The comestible units made in accordance with the present invention can include active ingredients and are capable of dissolving in the mouth of the consumer within several seconds. They are particularly useful as antacids and as delivery vehicles for biologically active ingredients, especially those which are ideally combined with antacid ingredients.
摘要翻译： 本发明涉及一种制造可食用单元的装置。 根据本发明制成的可食用单元可以包括活性成分，并且能够在几秒钟内溶解在消费者的口中。 它们作为抗酸剂和作为生物活性成分的输送载体特别有用，特别是那些理想地与抗酸成分组合的成分。
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6.发明授权Process and apparatus for making rapidly dissolving dosage units and product therefrom 失效用于制备快速溶解剂量单位和产品的方法和设备
公开(公告)号：US5622719A
公开(公告)日：1997-04-22
申请号：US652252
申请日：1996-05-23
IPC分类号： A23G3/00 , A23G3/10 , A23G3/34 , A23G3/36 , A61K9/00 , A61K9/20 , A61K9/70 , C13B30/02 , C13B50/00 , A61K9/46
CPC分类号： A23G3/368 , A23G3/10 , A23G3/346 , A61K9/0056 , A61K9/2018 , A61K9/2095 , A61K9/70 , C13B30/021 , C13B50/00 , A23G2200/06 , A61F2013/0296 , Y10S514/819 , Y10S514/948 , Y10S514/96 , Y10S514/965
摘要： The present invention is a method of preparing rapidly dissolving comestible units such as tablets. The present invention also includes an apparatus for making the comestible units and the units themselves. The product prepared in accordance with the present invention can include active ingredients and is capable of dissolving in the mouth of the consumer within several seconds. The unit dosage forms prepared in accordance with the present invention are particularly useful as antacids and as a delivery vehicle for biologically active ingredients, especially those which are ideally combined with antacid ingredients in order to ameliorate the effects of antacid environment.
摘要翻译： 本发明是制备片剂等快速溶解性食品的方法。 本发明还包括一种用于制造可食用单元和单元本身的装置。 根据本发明制备的产品可以包括活性成分，并且能够在几秒钟内溶解在消费者的口中。 根据本发明制备的单位剂型特别可用作抗酸剂和用作生物活性成分的输送载体，特别是那些理想地与抗酸成分组合以改善抗酸环境的作用的那些。
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7.发明授权Process and apparatus for making rapidly dissolving dosage units and product therefrom 失效用于制备快速溶解剂量单位和产品的方法和设备
公开(公告)号：US5866163A
公开(公告)日：1999-02-02
申请号：US772023
申请日：1996-12-19
IPC分类号： A23G3/00 , A23G3/10 , A23G3/34 , A23G3/36 , A61K9/00 , A61K9/20 , A61K9/70 , C13B30/02 , C13B50/00 , A61K9/26
CPC分类号： A23G3/368 , A23G3/10 , A23G3/346 , A61K9/0056 , A61K9/2018 , A61K9/2095 , A61K9/70 , C13B30/021 , C13B50/00 , A23G2200/06 , A61F2013/0296 , Y10S514/819 , Y10S514/948 , Y10S514/96 , Y10S514/965
摘要： The present invention is a method of preparing rapidly dissolving comestible units such as tablets. The present invention also includes an apparatus for making the comestible units and the units themselves. The product prepared in accordance with the present invention can include active ingredients and is capable of dissolving in the mouth of the consumer within several seconds. The unit dosage forms prepared in accordance with the present invention are particularly useful as antacids and as a delivery vehicle for biologically active ingredients, especially those which are ideally combined with antacid ingredients in order to ameliorate the effects of antacid environment.
摘要翻译： 本发明是制备片剂等快速溶解性食品的方法。 本发明还包括一种用于制造可食用单元和单元本身的装置。 根据本发明制备的产品可以包括活性成分，并且能够在几秒钟内溶解在消费者的口中。 根据本发明制备的单位剂型特别可用作抗酸剂和用作生物活性成分的输送载体，特别是那些理想地与抗酸成分组合以改善抗酸环境的作用的那些。
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公开(公告)号：US5853762A
公开(公告)日：1998-12-29
申请号：US698922
申请日：1996-08-16
IPC分类号： A61K9/16 , A23G3/00 , A23G3/10 , A23G3/36 , A61J3/10 , A61K9/00 , A61K9/20 , A61K9/22 , A61K9/46 , A61K9/70 , B30B11/02 , A61K31/70 , A61K47/36
CPC分类号： A23G3/368 , A23G3/10 , A61J3/10 , A61K9/0056 , A61K9/2018 , A61K9/2095 , A61K9/70 , B30B11/027
摘要： The present invention is a method and a dosage unit for delivery of a controlled-release system. The dosage unit is a quick dissolve unit which can be prepared by mixing uncured shearform matrix and a controlled-release system, either molding or compacting a unit dosage form and curing the shearform matrix. The controlled-release systems used in the present invention include instantaneous release components, delayed release components, sustained release components, and combinations thereof.
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公开(公告)号：US5851552A
公开(公告)日：1998-12-22
申请号：US698907
申请日：1996-08-16
IPC分类号： A61K9/16 , A23G3/00 , A23G3/10 , A23G3/36 , A61J3/10 , A61K9/00 , A61K9/20 , A61K9/22 , A61K9/46 , A61K9/70 , B30B11/02
CPC分类号： A23G3/368 , A23G3/10 , A61J3/10 , A61K9/0056 , A61K9/2018 , A61K9/2095 , A61K9/70 , B30B11/027
摘要： The present invention is a method and a dosage unit for delivery of a controlled-release system. The dosage unit is a quick dissolve unit which can be prepared by mixing uncured shearform matrix and a controlled-release system, either molding or compacting a unit dosage form and curing the shearform matrix. The controlled-release systems used in the present invention include instantaneous release components, delayed release components, sustained release components, and combinations thereof.
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公开(公告)号：US5733577A
公开(公告)日：1998-03-31
申请号：US698906
申请日：1996-08-16
IPC分类号： A61K9/16 , A23G3/00 , A23G3/10 , A23G3/36 , A61J3/10 , A61K9/00 , A61K9/20 , A61K9/22 , A61K9/46 , A61K9/70 , B30B11/02
CPC分类号： A23G3/368 , A23G3/10 , A61J3/10 , A61K9/0056 , A61K9/2018 , A61K9/2095 , A61K9/70 , B30B11/027
摘要： The present invention is a method and a dosage unit for delivery of a controlled-release system. The dosage unit is a quick dissolve unit which can be prepared by mixing uncured shearform matrix and a controlled-release system, either molding or compacting a unit dosage form and curing the shearform matrix. The controlled-release systems used in the present invention include instantaneous release components, delayed release components, sustained release components, and combinations thereof.
摘要翻译： 本发明是用于递送受控释放系统的方法和剂量单元。 剂量单位是快速溶解单元，其可以通过混合未固化的剪切形式基质和控制释放系统来制备，模制或压实单位剂型并固化剪切矩阵。 用于本发明的控制释放系统包括瞬时释放组分，延迟释放组分，缓释组分及其组合。
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