公开(公告)号：US20060057225A1

公开(公告)日：2006-03-16

申请号：US11263700

申请日：2005-11-01

Applicant: Lorraine Pena ,  Dennis Huczek

Inventor： Lorraine Pena ,  Dennis Huczek

IPC: A61K33/24 ,  A61K9/20

CPC classification number: A61K9/0095 ,  A61K31/28 ,  A61K31/29 ,  A61K31/60 ,  A61K33/245 ,  A61K47/36 ,  A61K47/38 ,  Y10S514/819 ,  Y10S514/867 ,  Y10S514/925 ,  Y10S514/937 ,  Y10S514/97 ,  Y10S514/974 ,  Y10S514/975

Abstract: The present invention provides a pharmaceutical composition comprising at least one pharmaceutically acceptable bismuth-containing compound, at least one pharmaceutically acceptable non-clay-derived suspending agent, and water. The suspension exhibits reduced upward pH drift by comparison with an otherwise similar suspension which comprises a clay-derived suspending agent. Such compositions are useful in the prevention and treatment of gastrointestinal diseases and/or disorders.

公开(公告)号：US20050035177A1

公开(公告)日：2005-02-17

申请号：US10832084

申请日：2004-04-26

Applicant: Fernando Palafox

Inventor： Fernando Palafox

IPC: A61K9/00 ,  A61K31/191 ,  A61K31/29 ,  A61K33/24 ,  C07F9/94 ,  B23K1/00

CPC classification number: A61K9/0095 ,  A61K31/191 ,  A61K31/29 ,  A61K33/245 ,  C07F9/94 ,  Y10S514/819

Abstract: A method for preparation of a semitransparent colloidal solution of bismuth sodium tartrate generally comprises producing an aqueous solution of bismuth sodium tartrate; extracting a magma of bismuth sodium tartrate from the aqueous solution at a pH of approximately 2.2; and then dissolving the magma into a salting-in mixture. After addition of preservative and strength testing, the base solution is diluted to elixir strength. The elixir is then buffered to a pH range of about 7.2 to about 7.3 in order to maintain for an extended duration the semitransparent nature of the elixir.

Abstract translation: 酒石酸铋钠半透明胶体溶液的制备方法一般包括制备酒石酸铋钠水溶液; 在大约2.2的pH下从水溶液中提取酒石酸铋钠的岩浆; 然后将岩浆溶解成盐析混合物。 加入防腐剂和强度试验后，将碱溶液稀释至酏剂强度。 然后将酏剂缓冲至约7.2至约7.3的pH范围，以便延长持续时间，以保持酏剂的半透明性质。

公开(公告)号：US06790462B2

公开(公告)日：2004-09-14

申请号：US10214635

申请日：2002-08-08

Applicant: Lewis Hendricks

Inventor： Lewis Hendricks

IPC: A61K3306

CPC classification number: A61K31/714 ,  A61K31/4415 ,  A61K31/525 ,  A61K31/592 ,  A61K33/06 ,  A61K33/42 ,  Y10S514/819 ,  Y10S514/825 ,  Y10S514/904 ,  Y10S514/905 ,  Y10S514/96 ,  A61K2300/00

Abstract: A dietary supplement composition contains phosphorus and from greater than 1.3 to less than 2.2 parts by weight calcium per part by weight phosphorus, and may, optionally, further contain Vitamin D, Vitamin B12, folate and Vitamin B6, provides components that have been linked to bone health.

Abstract translation: 膳食补充剂组合物含有磷，并且每重量份磷含量大于1.3至小于2.2重量份的钙，并且可以任选地还含有维生素D，维生素B12，叶酸和维生素B6，提供已经连接到 骨骼健康。

公开(公告)号：US20030031726A1

公开(公告)日：2003-02-13

申请号：US10214635

申请日：2002-08-08

Inventor： Lewis Hendricks

IPC: A61K033/42 ,  A01N059/26

CPC classification number: A61K31/714 ,  A61K31/4415 ,  A61K31/525 ,  A61K31/592 ,  A61K33/06 ,  A61K33/42 ,  Y10S514/819 ,  Y10S514/825 ,  Y10S514/904 ,  Y10S514/905 ,  Y10S514/96 ,  A61K2300/00

Abstract: A dietary supplement composition contains phosphorus and from greater than 1.3 to less than 2.2 parts by weight calcium per part by weight phosphorus, and may, optionally, further contain Vitamin D, Vitamin B12, folate and Vitamin B6, provides components that have been linked to bone health.

Abstract translation: 膳食补充剂组合物含有磷，并且每重量份磷含量大于1.3至小于2.2重量份的钙，并且可以任选地还含有维生素D，维生素B12，叶酸和维生素B6，提供已经连接到 骨骼健康。

公开(公告)号：US20020197333A1

公开(公告)日：2002-12-26

申请号：US10196082

申请日：2002-07-15

Inventor： Joel Swinson ,  Richard D. Giles ,  Jack Pitkin ,  Glenda Fleming ,  David B. Blum

IPC: A61K033/08

CPC classification number: A61K9/0014 ,  A61K33/10 ,  A61K47/02 ,  A61K47/10 ,  C01F7/004 ,  C01P2006/22 ,  C08J9/125 ,  C08J2207/02 ,  C08J2303/02 ,  C08L2666/28 ,  C09J5/08 ,  C09J103/02 ,  C09J2403/00 ,  Y10S514/819 ,  Y10S514/82 ,  Y10S514/925 ,  Y10S514/926 ,  Y10S514/927 ,  Y10S514/928 ,  Y10S514/937 ,  Y10S514/951 ,  Y10S514/952

Abstract: The present invention provides DASC compositions, which upon introduction into aqueous solutions, form stable, non-gritty suspensions. The present invention also provides stable, non-gritty suspensions comprising the DASC compositions of the present invention admixed in aqueous solutions. In addition, the present invention provides processes for preparing the suspensions which comprise admixing the DASC compositions of the present invention with aqueous solutions. Finally, the present invention provides processes for preparing the DASC compositions of the present invention.

公开(公告)号：US5976578A

公开(公告)日：1999-11-02

申请号：US932625

申请日：1997-09-17

Applicant: Douglas S. Beyerle ,  John Case ,  Gerard P. McNally ,  Frank Hatch

Inventor： Douglas S. Beyerle ,  John Case ,  Gerard P. McNally ,  Frank Hatch

IPC: A61K9/08 ,  A61K9/00 ,  A61K31/34 ,  A61K47/14 ,  A61P1/14 ,  A61K33/10 ,  A61K33/08

CPC classification number: A61K9/0095 ,  Y10S514/819

Abstract: Liquid antacid compositions containing a tri- or di-ester buffer have a reduced final product pH providing for a more efficacious preservative system and better tasting product without compromising to acid neutralization capacity of the antacid.

Abstract translation: 含有三酯或二酯缓冲液的液体抗酸组合物具有降低的最终产品pH，从而提供更有效的防腐剂体系和更好的品尝产品，而不会影响抗酸剂的酸中和能力。

公开(公告)号：US5843466A

公开(公告)日：1998-12-01

申请号：US629598

申请日：1996-04-09

Applicant: Jean M. Mane ,  Jean-Louis Ponge

Inventor： Jean M. Mane ,  Jean-Louis Ponge

IPC: A23G3/00 ,  A23G3/36 ,  A23G4/00 ,  A23G4/06 ,  A23L27/00 ,  A23L27/20 ,  A24B13/00 ,  A24B15/12 ,  A24B15/14 ,  A24B15/40 ,  A24D3/14 ,  A24F23/00 ,  A61K8/37 ,  A61K47/00 ,  A61K47/14 ,  A61Q11/00 ,  C07C35/12 ,  A61K9/14 ,  A61K9/20 ,  A61K9/68

CPC classification number: A23G3/36 ,  A23G4/06 ,  A23L27/203 ,  A24D3/14 ,  A61K8/37 ,  A61Q11/00 ,  A61K2800/244 ,  Y10S514/819 ,  Y10S514/844 ,  Y10S514/849 ,  Y10S514/853 ,  Y10S514/887

Abstract: Coolant compositions, flavorant compositions and ingestible and topical compositions containing at least one coolant compound selected from monomenthyl succinate, alkali metal salts of monomenthyl succinate, alkaline earth metal salts of monomenthyl succinate and mixtures thereof. These compositions are found to provide a pleasant, long-lasting cooling effect without bitterness and the cooling effect manifests itself differently than the cooling effect of other known coolants. As a result, a complementary or synergistic effect can by obtained by combination with other coolants. Further, the succinate-based coolant compounds of the invention are found to enhance the sensation of alcohol in alcoholic beverages.

Abstract translation: 含有至少一种选自琥珀酸单琥珀酸盐的冷却剂化合物，琥珀酸单薄荷酯的碱金属盐，琥珀酸单薄荷酯的碱土金属盐及其混合物的冷冻剂组合物，食用香料组合物和含有至少一种冷却剂化合物的摄入和局部组合物。 发现这些组合物提供了令人愉快的持久的冷却效果而没有苦味，并且冷却效果本身与其它已知的冷却剂的冷却效果不同。 结果，可以通过与其它冷却剂组合获得互补或协同效应。 此外，发现本发明的琥珀酸酯类冷却剂化合物增强酒精饮料中酒精的感觉。

公开(公告)号：US5543153A

公开(公告)日：1996-08-06

申请号：US204574

申请日：1994-03-01

Applicant: William C. Walton

Inventor： William C. Walton

IPC: A61K9/00 ,  A61K9/46 ,  A61K31/19 ,  A61K31/194 ,  A61K33/10 ,  A61P1/00 ,  A61K9/20

CPC classification number: A61K33/10 ,  A61K9/0007 ,  A61K9/0056 ,  Y10S514/819 ,  Y10S514/948

Abstract: A solid effervescent antacid formulation comprising as primary ingredients from about 35 to about 53 percent by weight of calcium carbonate, from about 0 to about 14 percent by weight of magnesium carbonate, from about 3.5 to about 7 percent by weight of a bicarbonate salt, from about 3.5 to about 7 percent by weight of malic acid and from about 21 to about 35 percent by weight of a bulking agent.

Abstract translation: 固体泡腾抗酸剂制剂，其包含约35至约53重量％的碳酸钙，约0至约14重量％的碳酸镁，约3.5至约7重量％的碳酸氢盐的主要成分，来自 约3.5至约7重量％的苹果酸和约21至约35重量％的填充剂。

公开(公告)号：US5527548A

公开(公告)日：1996-06-18

申请号：US367190

申请日：1995-01-13

Applicant: Carlos Tyortyalian

Inventor： Carlos Tyortyalian

IPC: A23C9/18 ,  A21D2/24 ,  A23F3/14 ,  A23F5/14 ,  A23G3/00 ,  A23G3/34 ,  A23L1/03 ,  A23L1/30 ,  A23L1/39 ,  A23L2/52 ,  A61K31/4184 ,  A61P1/14 ,  A61K31/415

CPC classification number: A21D2/24 ,  A23L29/045 ,  Y10S514/819 ,  Y10S514/926 ,  Y10S514/927

Abstract: A method for promoting digestibility of a food product having an acid character which, when ingested, causes stimulation and hypersecretion of gastric and/or duodenum mucosae. The method comprises incorporating into the food product a sufficient amount of benzimidazole or a benzimidazole compound of the formula: ##STR1## where X and Y independently represent an alkyl group, a phenyl group or a halogen atom and n=1 to 4.

Abstract translation: PCT No.PCT / FR93 / 00716 Sec。 371日期1995年1月13日 102（e）1995年1月13日PCT PCT 1993年7月13日PCT公布。 第WO94 / 02035号公报 日期：1994年2月3日。一种用于促进具有酸性特征的食品的消化率的方法，其在摄入时引起胃和/或十二指肠粘膜的刺激​​和分泌过多。 该方法包括向食品中加入足量的下式的苯并咪唑或苯并咪唑化合物：其中X和Y独立地表示烷基，苯基或卤素原子，n = 1-4。

公开(公告)号：US5439894A

公开(公告)日：1995-08-08

申请号：US150717

申请日：1993-11-12

Applicant: Donald S. Davies

Inventor： Donald S. Davies

IPC: A61K31/715 ,  A61P3/06 ,  A61P7/00 ,  C08B31/00 ,  C08B31/12 ,  A61K31/73

CPC classification number: C08B31/125 ,  Y10S514/819 ,  Y10S514/823

Abstract: Disclosed is a pharmaceutical composition comprising a dextrin derivative in which a proportion of the hydroxyl groups of dextrin are replaced by basic groups. Such compositions are useful for the treatment of acidic conditions.

Abstract translation: 公开了包含糊精衍生物的药物组合物，其中糊精的一部分羟基被碱性基团代替。 这些组合物可用于治疗酸性条件。