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公开(公告)号：US5851553A
公开(公告)日：1998-12-22
申请号：US772024
申请日：1996-12-19
IPC分类号： A23G3/00 , A23G3/10 , A23G3/34 , A23G3/36 , A61K9/00 , A61K9/20 , A61K9/70 , C13B30/02 , A61K9/22
CPC分类号： A23G3/10 , A23G3/346 , A23G3/368 , A61K9/0056 , A61K9/2018 , A61K9/2095 , A61K9/70 , C13B30/021 , C13B50/00 , A23G2200/06 , A61F2013/0296 , Y10S514/96
摘要： The present invention is a method of preparing rapidly dissolving comestible units such as tablets. The present invention also includes an apparatus for making the comestible units and the units themselves. The product prepared in accordance with the present invention can include active ingredients and is capable of dissolving in the mouth of the consumer within several seconds. The unit dosage forms prepared in accordance with the present invention are particularly useful as antacids and as a delivery vehicle for biologically active ingredients, especially those which are ideally combined with antacid ingredients in order to ameliorate the effects of antacid environment.
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公开(公告)号：US5866188A
公开(公告)日：1999-02-02
申请号：US982128
申请日：1997-12-01
IPC分类号： A21D15/08 , A23G3/00 , A23G3/10 , A23G3/34 , A23G3/36 , A61K9/00 , A61K9/20 , A61K9/70 , C13B30/02 , C13B50/00 , C13K1/10 , C13K13/00 , C13F1/02 , C13F3/00 , A21O13/00 , A21O13/08
CPC分类号： A23G3/368 , A23G3/10 , A23G3/346 , A61K9/2018 , A61K9/2095 , A61K9/70 , C13B30/021 , C13B50/00 , A23G2200/06 , A61K9/0056
摘要： The present invention is a comestible composition including a new spheroidal polycrystallite product. In the present invention amorphous sugar is transformed to crystalline sugar by hydrating rather than dehydrating sugar.
摘要翻译： 本发明是包含新型球状多晶产品的食品组合物。 在本发明中，无定形糖通过水合而不是脱水糖转化成结晶糖。
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公开(公告)号：US5871781A
公开(公告)日：1999-02-16
申请号：US772022
申请日：1996-12-19
IPC分类号： A23G3/00 , A23G3/10 , A23G3/34 , A23G3/36 , A61K9/00 , A61K9/20 , A61K9/70 , C13B30/02 , C13B50/00 , B29C43/00
CPC分类号： A23G3/368 , A23G3/10 , A23G3/346 , A61K9/0056 , A61K9/2018 , A61K9/2095 , A61K9/70 , C13B30/021 , C13B50/00 , A23G2200/06 , A61F2013/0296 , Y10S514/819 , Y10S514/948 , Y10S514/96 , Y10S514/965
摘要： The present invention involves an apparatus for making comestible units. The comestible units made in accordance with the present invention can include active ingredients and are capable of dissolving in the mouth of the consumer within several seconds. They are particularly useful as antacids and as delivery vehicles for biologically active ingredients, especially those which are ideally combined with antacid ingredients.
摘要翻译： 本发明涉及一种制造可食用单元的装置。 根据本发明制成的可食用单元可以包括活性成分，并且能够在几秒钟内溶解在消费者的口中。 它们作为抗酸剂和作为生物活性成分的输送载体特别有用，特别是那些理想地与抗酸成分组合的成分。
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4.发明授权Process and apparatus for making rapidly dissolving dosage units and product therefrom 失效用于制备快速溶解剂量单位和产品的方法和设备
公开(公告)号：US5622719A
公开(公告)日：1997-04-22
申请号：US652252
申请日：1996-05-23
IPC分类号： A23G3/00 , A23G3/10 , A23G3/34 , A23G3/36 , A61K9/00 , A61K9/20 , A61K9/70 , C13B30/02 , C13B50/00 , A61K9/46
CPC分类号： A23G3/368 , A23G3/10 , A23G3/346 , A61K9/0056 , A61K9/2018 , A61K9/2095 , A61K9/70 , C13B30/021 , C13B50/00 , A23G2200/06 , A61F2013/0296 , Y10S514/819 , Y10S514/948 , Y10S514/96 , Y10S514/965
摘要： The present invention is a method of preparing rapidly dissolving comestible units such as tablets. The present invention also includes an apparatus for making the comestible units and the units themselves. The product prepared in accordance with the present invention can include active ingredients and is capable of dissolving in the mouth of the consumer within several seconds. The unit dosage forms prepared in accordance with the present invention are particularly useful as antacids and as a delivery vehicle for biologically active ingredients, especially those which are ideally combined with antacid ingredients in order to ameliorate the effects of antacid environment.
摘要翻译： 本发明是制备片剂等快速溶解性食品的方法。 本发明还包括一种用于制造可食用单元和单元本身的装置。 根据本发明制备的产品可以包括活性成分，并且能够在几秒钟内溶解在消费者的口中。 根据本发明制备的单位剂型特别可用作抗酸剂和用作生物活性成分的输送载体，特别是那些理想地与抗酸成分组合以改善抗酸环境的作用的那些。
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5.发明授权Process and apparatus for making rapidly dissolving dosage units and product therefrom 失效用于制备快速溶解剂量单位和产品的方法和设备
公开(公告)号：US5866163A
公开(公告)日：1999-02-02
申请号：US772023
申请日：1996-12-19
IPC分类号： A23G3/00 , A23G3/10 , A23G3/34 , A23G3/36 , A61K9/00 , A61K9/20 , A61K9/70 , C13B30/02 , C13B50/00 , A61K9/26
CPC分类号： A23G3/368 , A23G3/10 , A23G3/346 , A61K9/0056 , A61K9/2018 , A61K9/2095 , A61K9/70 , C13B30/021 , C13B50/00 , A23G2200/06 , A61F2013/0296 , Y10S514/819 , Y10S514/948 , Y10S514/96 , Y10S514/965
摘要： The present invention is a method of preparing rapidly dissolving comestible units such as tablets. The present invention also includes an apparatus for making the comestible units and the units themselves. The product prepared in accordance with the present invention can include active ingredients and is capable of dissolving in the mouth of the consumer within several seconds. The unit dosage forms prepared in accordance with the present invention are particularly useful as antacids and as a delivery vehicle for biologically active ingredients, especially those which are ideally combined with antacid ingredients in order to ameliorate the effects of antacid environment.
摘要翻译： 本发明是制备片剂等快速溶解性食品的方法。 本发明还包括一种用于制造可食用单元和单元本身的装置。 根据本发明制备的产品可以包括活性成分，并且能够在几秒钟内溶解在消费者的口中。 根据本发明制备的单位剂型特别可用作抗酸剂和用作生物活性成分的输送载体，特别是那些理想地与抗酸成分组合以改善抗酸环境的作用的那些。
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公开(公告)号：US5853762A
公开(公告)日：1998-12-29
申请号：US698922
申请日：1996-08-16
IPC分类号： A61K9/16 , A23G3/00 , A23G3/10 , A23G3/36 , A61J3/10 , A61K9/00 , A61K9/20 , A61K9/22 , A61K9/46 , A61K9/70 , B30B11/02 , A61K31/70 , A61K47/36
CPC分类号： A23G3/368 , A23G3/10 , A61J3/10 , A61K9/0056 , A61K9/2018 , A61K9/2095 , A61K9/70 , B30B11/027
摘要： The present invention is a method and a dosage unit for delivery of a controlled-release system. The dosage unit is a quick dissolve unit which can be prepared by mixing uncured shearform matrix and a controlled-release system, either molding or compacting a unit dosage form and curing the shearform matrix. The controlled-release systems used in the present invention include instantaneous release components, delayed release components, sustained release components, and combinations thereof.
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公开(公告)号：US5851552A
公开(公告)日：1998-12-22
申请号：US698907
申请日：1996-08-16
IPC分类号： A61K9/16 , A23G3/00 , A23G3/10 , A23G3/36 , A61J3/10 , A61K9/00 , A61K9/20 , A61K9/22 , A61K9/46 , A61K9/70 , B30B11/02
CPC分类号： A23G3/368 , A23G3/10 , A61J3/10 , A61K9/0056 , A61K9/2018 , A61K9/2095 , A61K9/70 , B30B11/027
摘要： The present invention is a method and a dosage unit for delivery of a controlled-release system. The dosage unit is a quick dissolve unit which can be prepared by mixing uncured shearform matrix and a controlled-release system, either molding or compacting a unit dosage form and curing the shearform matrix. The controlled-release systems used in the present invention include instantaneous release components, delayed release components, sustained release components, and combinations thereof.
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公开(公告)号：US5733577A
公开(公告)日：1998-03-31
申请号：US698906
申请日：1996-08-16
IPC分类号： A61K9/16 , A23G3/00 , A23G3/10 , A23G3/36 , A61J3/10 , A61K9/00 , A61K9/20 , A61K9/22 , A61K9/46 , A61K9/70 , B30B11/02
CPC分类号： A23G3/368 , A23G3/10 , A61J3/10 , A61K9/0056 , A61K9/2018 , A61K9/2095 , A61K9/70 , B30B11/027
摘要： The present invention is a method and a dosage unit for delivery of a controlled-release system. The dosage unit is a quick dissolve unit which can be prepared by mixing uncured shearform matrix and a controlled-release system, either molding or compacting a unit dosage form and curing the shearform matrix. The controlled-release systems used in the present invention include instantaneous release components, delayed release components, sustained release components, and combinations thereof.
摘要翻译： 本发明是用于递送受控释放系统的方法和剂量单元。 剂量单位是快速溶解单元，其可以通过混合未固化的剪切形式基质和控制释放系统来制备，模制或压实单位剂型并固化剪切矩阵。 用于本发明的控制释放系统包括瞬时释放组分，延迟释放组分，缓释组分及其组合。
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公开(公告)号：US5597416A
公开(公告)日：1997-01-28
申请号：US133669
申请日：1993-10-07
IPC分类号： A23G3/00 , A23G3/10 , A23G3/34 , A23G3/36 , A23L27/00 , A61K9/00 , A61K9/20 , A61K9/70 , A61K47/26 , C07H1/00 , C13B30/02 , C13B50/00 , C13F3/00 , C13F9/02
CPC分类号： A23G3/368 , A23G3/10 , A61K9/2018 , A61K9/2095 , A61K9/70 , C13B30/021 , A61K9/0056
摘要： The present invention is a new crystalline sugar product and method of making same which includes forming a bi-dimensionally stabilized sugar crystalline frame from an outer portion of an amorphous shearform sugar mass, and, subsequently, converting the remaining portion of the mass to a substantially completely crystalline structure which retains the cross-sectional dimension of the sugar crystalline frame. The present invention also includes co-crystallizing an additive, especially a bio-affecting additive, during the process to provide a co-crystallized product. The structure of the crystallized product can also be loaded with a non-solvent liquid by force of capillary action in the space created within the structure during the conversion from amorphous mass to crystalline structure.
摘要翻译： 本发明是一种新的结晶糖产品及其制备方法，包括从无定形剪切糖块的外部形成二维稳定的糖结晶框架，随后将其余部分转化为基本上 完全晶体结构，保留了糖晶框架的横截面尺寸。 本发明还包括在提供共结晶产物的过程中共同结晶添加剂，特别是生物影响添加剂。 结晶产物的结构也可以在从无定形物质转变为结晶结构期间由结构内产生的空间中的毛细管作用力加载非溶剂液体。
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公开(公告)号：US5518551A
公开(公告)日：1996-05-21
申请号：US119974
申请日：1993-09-10
IPC分类号： A21D15/08 , A23G3/00 , A23G3/10 , A23G3/34 , A23G3/36 , A61K9/00 , A61K9/20 , A61K9/70 , C13B30/02 , C13B50/00 , C13K1/10 , C13K13/00 , C13F1/02
CPC分类号： A23G3/368 , A23G3/10 , A23G3/346 , A61K9/2018 , A61K9/2095 , A61K9/70 , C13B30/021 , C13B50/00 , A23G2200/06 , A61K9/0056
摘要： The present invention is a new spheroidal polycrystallite product and a process for making the same. In the present invention amorphous sugar is transformed to crystalline sugar by hydrating rather than dehydrating sugar. The product of the present invention is unique in shape, size, and possesses a high degree of uniformity.
摘要翻译： 本发明是一种新的球形多晶产品及其制造方法。 在本发明中，无定形糖通过水合而不是脱水糖转化成结晶糖。 本发明的产品在形状，尺寸方面是独特的，并且具有高度的均匀性。
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