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1.发明申请公开(公告)号：US20050014802A1
公开(公告)日：2005-01-20
申请号：US10857458
申请日：2004-05-28
申请人： Giorgio Attardo , Kenza Dairi , Jean-Francois Lavallee , Elise Rioux , Sasmita Tripathy , Terrence Doyle , Xavier Billot
发明人： Giorgio Attardo , Kenza Dairi , Jean-Francois Lavallee , Elise Rioux , Sasmita Tripathy , Terrence Doyle , Xavier Billot
IPC分类号： C07D403/04 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D491/04 , C07F9/6558 , A61K31/433 , A61K31/4196 , A61K31/4245 , C07D417/14
CPC分类号： C07D403/14 , C07D403/04 , C07D405/14 , C07D409/14 , C07D413/14 , C07D491/04 , C07F9/65583
摘要： The present invention relates to novel Triheterocyclic Compounds, compositions comprising a Triheterocyclic Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering a Triheterocyclic Compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell, treating or preventing a viral infection, or inhibiting the replication and/or infectivity of a virus.
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公开(公告)号：US20080318903A1
公开(公告)日：2008-12-25
申请号：US12176161
申请日：2008-07-18
申请人： Giorgio Attardo , Kenza Dairi , Jean-Francois Lavallee , Elise Rioux , Sasmita Tripathy , Terrence W. Doyle , Xavuer Billot
发明人： Giorgio Attardo , Kenza Dairi , Jean-Francois Lavallee , Elise Rioux , Sasmita Tripathy , Terrence W. Doyle , Xavuer Billot
IPC分类号： A61K31/675 , A61P35/00 , A61K31/404
CPC分类号： C07D403/14 , C07D403/04 , C07D405/14 , C07D409/14 , C07D413/14 , C07D491/04 , C07F9/65583
摘要： The present invention relates to novel Triheterocyclic Compounds, compositions comprising a Triheterocyclic Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering a Triheterocyclic Compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell, treating or preventing a viral infection, or inhibiting the replication and/or infectivity of a virus.
摘要翻译： 本发明涉及新颖的三杂环化合物，包含三杂环化合物的组合物，以及可用于治疗或预防癌症或肿瘤性疾病的方法，包括给予三环杂环化合物。 本发明的化合物，组合物和方法也可用于抑制癌细胞或肿瘤细胞的生长，治疗或预防病毒感染，或抑制病毒的复制和/或感染性。
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公开(公告)号：US07709477B2
公开(公告)日：2010-05-04
申请号：US12176161
申请日：2008-07-18
IPC分类号： A61K31/497 , A61K31/40 , A61K31/42 , A61K31/44 , A61K31/535 , C07D209/14
CPC分类号： C07D403/14 , C07D403/04 , C07D405/14 , C07D409/14 , C07D413/14 , C07D491/04 , C07F9/65583
摘要： The present invention relates to novel Triheterocyclic Compounds, compositions comprising a Triheterocyclic Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering a Triheterocyclic Compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell, treating or preventing a viral infection, or inhibiting the replication and/or infectivity of a virus.
摘要翻译： 本发明涉及新型三杂环化合物，包含三杂环化合物的组合物，以及可用于治疗或预防癌症或肿瘤疾病的方法，其包括施用三环杂环化合物。 本发明的化合物，组合物和方法也可用于抑制癌细胞或肿瘤细胞的生长，治疗或预防病毒感染，或抑制病毒的复制和/或感染性。
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公开(公告)号：US07745435B2
公开(公告)日：2010-06-29
申请号：US12176123
申请日：2008-07-18
IPC分类号： A61K31/535 , A61K31/44 , A61K31/42 , A61K31/40 , A61K31/497 , C07D209/14
摘要： The present invention relates to novel Triheterocyclic Compounds, compositions comprising a Triheterocyclic Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering a Triheterocyclic Compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell, treating or preventing a viral infection, or inhibiting the replication and/or infectivity of a virus.
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公开(公告)号：US20080318902A1
公开(公告)日：2008-12-25
申请号：US12176123
申请日：2008-07-18
IPC分类号： C07D401/14 , A61K31/4439 , A61K31/496 , A61K31/5377 , A61K31/404 , C07D413/14 , C07F9/572 , A61K31/675
CPC分类号： C07D403/14 , C07D403/04 , C07D405/14 , C07D409/14 , C07D413/14 , C07D491/04 , C07F9/65583
摘要： The present invention relates to novel Triheterocyclic Compounds, compositions comprising a Triheterocyclic Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering a Triheterocyclic Compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell, treating or preventing a viral infection, or inhibiting the replication and/or infectivity of a virus.
摘要翻译： 本发明涉及新颖的三杂环化合物，包含三杂环化合物的组合物，以及可用于治疗或预防癌症或肿瘤性疾病的方法，包括给予三环杂环化合物。 本发明的化合物，组合物和方法也可用于抑制癌细胞或肿瘤细胞的生长，治疗或预防病毒感染，或抑制病毒的复制和/或感染性。
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6.发明申请公开(公告)号：US20050032802A1
公开(公告)日：2005-02-10
申请号：US10865262
申请日：2004-06-10
申请人： Jean-Francois Lavallee , Terrence Doyle , Elise Rioux , Laurent Belec , Daniel Rabouin , Xavier Billot
发明人： Jean-Francois Lavallee , Terrence Doyle , Elise Rioux , Laurent Belec , Daniel Rabouin , Xavier Billot
IPC分类号： A61K31/085 , A61K31/121 , A61K31/495 , A61K31/502 , A61K31/517 , A61P35/00 , C07C43/162 , C07C43/164 , C07C45/29 , C07C49/115 , C07C49/225 , C07C49/755 , C07C69/00 , C07C323/59 , C07F9/117 , C07D237/36 , A61K31/498
CPC分类号： C07C45/292 , C07C49/755 , C07C69/757 , C07C323/59 , C07C2603/26 , C07F9/117
摘要： The present invention relates to Diterpenoid Compounds, compositions comprising an effective amount of a Diterpenoid Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering an effective amount of a Diterpenoid Compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell, or for inducing apoptosis in a cancer or neoplastic cell. The compounds, compositions, and methods of the invention are further useful for treating or preventing a fungal infection. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a fungus.
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7.发明授权Triheterocyclic compounds, compositions, and methods for treating cancer or viral diseases 有权三联环化合物，组合物和治疗癌症或病毒性疾病的方法公开(公告)号：US07425553B2
公开(公告)日：2008-09-16
申请号：US10857458
申请日：2004-05-28
IPC分类号： A61K31/535 , A61K31/44 , A61K31/42 , A61K31/40 , A61K31/497 , C07D209/14
CPC分类号： C07D403/14 , C07D403/04 , C07D405/14 , C07D409/14 , C07D413/14 , C07D491/04 , C07F9/65583
摘要： The present invention relates to novel Triheterocyclic Compounds, compositions comprising a Triheterocyclic Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering a Triheterocyclic Compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell, treating or preventing a viral infection, or inhibiting the replication and/or infectivity of a virus.
摘要翻译： 本发明涉及新颖的三杂环化合物，包含三杂环化合物的组合物，以及可用于治疗或预防癌症或肿瘤性疾病的方法，包括给予三环杂环化合物。 本发明的化合物，组合物和方法也可用于抑制癌细胞或肿瘤细胞的生长，治疗或预防病毒感染，或抑制病毒的复制和/或感染性。
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8.发明授权公开(公告)号：US07230139B2
公开(公告)日：2007-06-12
申请号：US10865262
申请日：2004-06-10
申请人： Jean-Francois Lavallee , Terrence W. Doyle , Elise Rioux , Laurent Belec , Daniel Rabouin , Xavier Billot , Samuel Fortin
发明人： Jean-Francois Lavallee , Terrence W. Doyle , Elise Rioux , Laurent Belec , Daniel Rabouin , Xavier Billot , Samuel Fortin
IPC分类号： C07C43/162 , C07C43/164 , C07C43/166 , C07C49/225 , C07D237/36 , C07D239/70 , A61K31/085 , A61K31/121 , A61K31/502 , A61K31/517 , A61P35/00
CPC分类号： C07C45/292 , C07C49/755 , C07C69/757 , C07C323/59 , C07C2603/26 , C07F9/117
摘要： The present invention relates to Diterpenoid Compounds, compositions comprising an effective amount of a Diterpenoid Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering an effective amount of a Diterpenoid Compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell, or for inducing apoptosis in a cancer or neoplastic cell. The compounds, compositions, and methods of the invention are further useful for treating or preventing a fungal infection. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a fungus.
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9.发明授权Dipyrrole compounds, compositions, and methods for treating cancer or viral diseases 有权二吡咯化合物，组合物和治疗癌症或病毒性疾病的方法公开(公告)号：US08420693B2
公开(公告)日：2013-04-16
申请号：US11794488
申请日：2005-12-22
IPC分类号： A61K31/40
CPC分类号： C07D207/44 , A61K31/4025 , A61K31/4439 , A61K31/4709 , A61K31/506 , A61K31/5377 , C07D401/14 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14
摘要： The present invention relates to novel Dipyrrole Compounds, compositions comprising a Dipyrrole Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering a Dipyrrole Compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell, treating or preventing a viral infection, or inhibiting the replication and/or infectivity of a virus. The invention also provides screening assays for compounds that can be used in combination with Dipyrrole Compounds for the treatment of cancer or neoplastic disease, inhibition of cancer cell growth, or treatment of viral infections.
摘要翻译： 本发明涉及新颖的二吡咯化合物，包含二吡咯化合物的组合物，以及可用于治疗或预防癌症或肿瘤性疾病的方法，包括施用二吡咯化合物。 本发明的化合物，组合物和方法也可用于抑制癌细胞或肿瘤细胞的生长，治疗或预防病毒感染，或抑制病毒的复制和/或感染性。 本发明还提供了可以与二吡咯化合物组合用于治疗癌症或肿瘤性疾病，抑制癌细胞生长或治疗病毒感染的化合物的筛选测定。
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10.发明申请Dipyrrole Compounds, Compositions, and Methods For Treating Cancer or Viral Diseases 有权二吡咯化合物，组合物和治疗癌症或病毒疾病的方法公开(公告)号：US20080280896A1
公开(公告)日：2008-11-13
申请号：US11794488
申请日：2005-12-22
IPC分类号： A61K31/538 , C07D403/06 , A61K31/4025 , A61P35/00 , C12N5/06 , C07D413/14
CPC分类号： C07D207/44 , A61K31/4025 , A61K31/4439 , A61K31/4709 , A61K31/506 , A61K31/5377 , C07D401/14 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14
摘要： The present invention relates to novel Dipyrrole Compounds, compositions comprising a Dipyrrole Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering a Dipyrrole Compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell, treating or preventing a viral infection, or inhibiting the replication and/or infectivity of a virus. The invention also provides screening assays for compounds that can be used in combination with Dipyrrole Compounds for the treatment of cancer or neoplastic disease, inhibition of cancer cell growth, or treatment of viral infections.
摘要翻译： 本发明涉及新颖的二吡咯化合物，包含二吡咯化合物的组合物，以及可用于治疗或预防癌症或肿瘤性疾病的方法，包括施用二吡咯化合物。 本发明的化合物，组合物和方法也可用于抑制癌细胞或肿瘤细胞的生长，治疗或预防病毒感染，或抑制病毒的复制和/或感染性。 本发明还提供了可以与二吡咯化合物组合用于治疗癌症或肿瘤性疾病，抑制癌细胞生长或治疗病毒感染的化合物的筛选测定。
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