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1.发明申请公开(公告)号：US20050014802A1
公开(公告)日：2005-01-20
申请号：US10857458
申请日：2004-05-28
申请人： Giorgio Attardo , Kenza Dairi , Jean-Francois Lavallee , Elise Rioux , Sasmita Tripathy , Terrence Doyle , Xavier Billot
发明人： Giorgio Attardo , Kenza Dairi , Jean-Francois Lavallee , Elise Rioux , Sasmita Tripathy , Terrence Doyle , Xavier Billot
IPC分类号： C07D403/04 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D491/04 , C07F9/6558 , A61K31/433 , A61K31/4196 , A61K31/4245 , C07D417/14
CPC分类号： C07D403/14 , C07D403/04 , C07D405/14 , C07D409/14 , C07D413/14 , C07D491/04 , C07F9/65583
摘要： The present invention relates to novel Triheterocyclic Compounds, compositions comprising a Triheterocyclic Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering a Triheterocyclic Compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell, treating or preventing a viral infection, or inhibiting the replication and/or infectivity of a virus.
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公开(公告)号：US20080318903A1
公开(公告)日：2008-12-25
申请号：US12176161
申请日：2008-07-18
申请人： Giorgio Attardo , Kenza Dairi , Jean-Francois Lavallee , Elise Rioux , Sasmita Tripathy , Terrence W. Doyle , Xavuer Billot
发明人： Giorgio Attardo , Kenza Dairi , Jean-Francois Lavallee , Elise Rioux , Sasmita Tripathy , Terrence W. Doyle , Xavuer Billot
IPC分类号： A61K31/675 , A61P35/00 , A61K31/404
CPC分类号： C07D403/14 , C07D403/04 , C07D405/14 , C07D409/14 , C07D413/14 , C07D491/04 , C07F9/65583
摘要： The present invention relates to novel Triheterocyclic Compounds, compositions comprising a Triheterocyclic Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering a Triheterocyclic Compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell, treating or preventing a viral infection, or inhibiting the replication and/or infectivity of a virus.
摘要翻译： 本发明涉及新颖的三杂环化合物，包含三杂环化合物的组合物，以及可用于治疗或预防癌症或肿瘤性疾病的方法，包括给予三环杂环化合物。 本发明的化合物，组合物和方法也可用于抑制癌细胞或肿瘤细胞的生长，治疗或预防病毒感染，或抑制病毒的复制和/或感染性。
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3.发明申请Triheterocyclic compounds, compositions, and methods for treating cancer or viral diseases 审中-公开三联环化合物，组合物和治疗癌症或病毒性疾病的方法公开(公告)号：US20050267073A1
公开(公告)日：2005-12-01
申请号：US11140367
申请日：2005-05-27
IPC分类号： A61K31/675 , C07D401/14 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D491/04 , C07F9/572 , C07F9/6558
CPC分类号： C07D491/04 , C07D401/14 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07F9/5728 , C07F9/65583
摘要： The present invention relates to novel Triheterocyclic Compounds, compositions comprising a Triheterocyclic Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering a Triheterocyclic Compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell, treating or preventing a viral infection, or inhibiting the replication and/or infectivity of a virus.
摘要翻译： 本发明涉及新颖的三杂环化合物，包含三杂环化合物的组合物，以及可用于治疗或预防癌症或肿瘤性疾病的方法，包括给予三环杂环化合物。 本发明的化合物，组合物和方法也可用于抑制癌细胞或肿瘤细胞的生长，治疗或预防病毒感染，或抑制病毒的复制和/或感染性。
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公开(公告)号：US20130040892A1
公开(公告)日：2013-02-14
申请号：US13578574
申请日：2011-02-11
申请人： Alain Laurent , Melanie Proulx , Yannick Rose , Irina Denissova , Kenza Dairi , Scott Jarvis , James B. Jaquith
发明人： Alain Laurent , Melanie Proulx , Yannick Rose , Irina Denissova , Kenza Dairi , Scott Jarvis , James B. Jaquith
IPC分类号： A61K38/05 , C12N5/078 , C12N5/0787 , A61P29/00 , C07D471/04 , A61P35/00 , A61P37/00 , C12N5/071 , C07K5/062
CPC分类号： C07K5/06026 , A61K38/00 , C07K5/06034
摘要： A compound of Formula 1: (I) or salt thereof, as well as methods of making compounds of Formula 1, methods of using compounds of Formula 1 to treat proliferative disorders such as cancer, and related compounds, composition, and methods.
摘要翻译： 式1化合物或其盐，以及制备式1化合物的方法，使用式1化合物治疗增殖性疾病如癌症的方法及其相关化合物，组合物和方法。
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公开(公告)号：US09284350B2
公开(公告)日：2016-03-15
申请号：US13578574
申请日：2011-02-11
申请人： Alain Laurent , Melanie Proulx , Yannick Rose , Irina Denissova , Kenza Dairi , Scott Jarvis , James B. Jaquith
发明人： Alain Laurent , Melanie Proulx , Yannick Rose , Irina Denissova , Kenza Dairi , Scott Jarvis , James B. Jaquith
CPC分类号： C07K5/06026 , A61K38/00 , C07K5/06034
摘要： A compound of Formula 1: (I) or salt thereof, as well as methods of making compounds of Formula 1, methods of using compounds of Formula 1 to treat proliferative disorders such as cancer, and related compounds, composition, and methods.
摘要翻译： 式1化合物或其盐，以及制备式1化合物的方法，使用式1化合物治疗增殖性疾病如癌症的方法及其相关化合物，组合物和方法。
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