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公开(公告)号：US20080318903A1
公开(公告)日：2008-12-25
申请号：US12176161
申请日：2008-07-18
申请人： Giorgio Attardo , Kenza Dairi , Jean-Francois Lavallee , Elise Rioux , Sasmita Tripathy , Terrence W. Doyle , Xavuer Billot
发明人： Giorgio Attardo , Kenza Dairi , Jean-Francois Lavallee , Elise Rioux , Sasmita Tripathy , Terrence W. Doyle , Xavuer Billot
IPC分类号： A61K31/675 , A61P35/00 , A61K31/404
CPC分类号： C07D403/14 , C07D403/04 , C07D405/14 , C07D409/14 , C07D413/14 , C07D491/04 , C07F9/65583
摘要： The present invention relates to novel Triheterocyclic Compounds, compositions comprising a Triheterocyclic Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering a Triheterocyclic Compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell, treating or preventing a viral infection, or inhibiting the replication and/or infectivity of a virus.
摘要翻译： 本发明涉及新颖的三杂环化合物，包含三杂环化合物的组合物，以及可用于治疗或预防癌症或肿瘤性疾病的方法，包括给予三环杂环化合物。 本发明的化合物，组合物和方法也可用于抑制癌细胞或肿瘤细胞的生长，治疗或预防病毒感染，或抑制病毒的复制和/或感染性。
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2.发明申请公开(公告)号：US20050014802A1
公开(公告)日：2005-01-20
申请号：US10857458
申请日：2004-05-28
申请人： Giorgio Attardo , Kenza Dairi , Jean-Francois Lavallee , Elise Rioux , Sasmita Tripathy , Terrence Doyle , Xavier Billot
发明人： Giorgio Attardo , Kenza Dairi , Jean-Francois Lavallee , Elise Rioux , Sasmita Tripathy , Terrence Doyle , Xavier Billot
IPC分类号： C07D403/04 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D491/04 , C07F9/6558 , A61K31/433 , A61K31/4196 , A61K31/4245 , C07D417/14
CPC分类号： C07D403/14 , C07D403/04 , C07D405/14 , C07D409/14 , C07D413/14 , C07D491/04 , C07F9/65583
摘要： The present invention relates to novel Triheterocyclic Compounds, compositions comprising a Triheterocyclic Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering a Triheterocyclic Compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell, treating or preventing a viral infection, or inhibiting the replication and/or infectivity of a virus.
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公开(公告)号：US07709477B2
公开(公告)日：2010-05-04
申请号：US12176161
申请日：2008-07-18
IPC分类号： A61K31/497 , A61K31/40 , A61K31/42 , A61K31/44 , A61K31/535 , C07D209/14
CPC分类号： C07D403/14 , C07D403/04 , C07D405/14 , C07D409/14 , C07D413/14 , C07D491/04 , C07F9/65583
摘要： The present invention relates to novel Triheterocyclic Compounds, compositions comprising a Triheterocyclic Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering a Triheterocyclic Compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell, treating or preventing a viral infection, or inhibiting the replication and/or infectivity of a virus.
摘要翻译： 本发明涉及新型三杂环化合物，包含三杂环化合物的组合物，以及可用于治疗或预防癌症或肿瘤疾病的方法，其包括施用三环杂环化合物。 本发明的化合物，组合物和方法也可用于抑制癌细胞或肿瘤细胞的生长，治疗或预防病毒感染，或抑制病毒的复制和/或感染性。
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公开(公告)号：US07745435B2
公开(公告)日：2010-06-29
申请号：US12176123
申请日：2008-07-18
IPC分类号： A61K31/535 , A61K31/44 , A61K31/42 , A61K31/40 , A61K31/497 , C07D209/14
摘要： The present invention relates to novel Triheterocyclic Compounds, compositions comprising a Triheterocyclic Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering a Triheterocyclic Compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell, treating or preventing a viral infection, or inhibiting the replication and/or infectivity of a virus.
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公开(公告)号：US20080318902A1
公开(公告)日：2008-12-25
申请号：US12176123
申请日：2008-07-18
IPC分类号： C07D401/14 , A61K31/4439 , A61K31/496 , A61K31/5377 , A61K31/404 , C07D413/14 , C07F9/572 , A61K31/675
CPC分类号： C07D403/14 , C07D403/04 , C07D405/14 , C07D409/14 , C07D413/14 , C07D491/04 , C07F9/65583
摘要： The present invention relates to novel Triheterocyclic Compounds, compositions comprising a Triheterocyclic Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering a Triheterocyclic Compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell, treating or preventing a viral infection, or inhibiting the replication and/or infectivity of a virus.
摘要翻译： 本发明涉及新颖的三杂环化合物，包含三杂环化合物的组合物，以及可用于治疗或预防癌症或肿瘤性疾病的方法，包括给予三环杂环化合物。 本发明的化合物，组合物和方法也可用于抑制癌细胞或肿瘤细胞的生长，治疗或预防病毒感染，或抑制病毒的复制和/或感染性。
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6.发明授权Triheterocyclic compounds, compositions, and methods for treating cancer or viral diseases 有权三联环化合物，组合物和治疗癌症或病毒性疾病的方法公开(公告)号：US07425553B2
公开(公告)日：2008-09-16
申请号：US10857458
申请日：2004-05-28
IPC分类号： A61K31/535 , A61K31/44 , A61K31/42 , A61K31/40 , A61K31/497 , C07D209/14
CPC分类号： C07D403/14 , C07D403/04 , C07D405/14 , C07D409/14 , C07D413/14 , C07D491/04 , C07F9/65583
摘要： The present invention relates to novel Triheterocyclic Compounds, compositions comprising a Triheterocyclic Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering a Triheterocyclic Compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell, treating or preventing a viral infection, or inhibiting the replication and/or infectivity of a virus.
摘要翻译： 本发明涉及新颖的三杂环化合物，包含三杂环化合物的组合物，以及可用于治疗或预防癌症或肿瘤性疾病的方法，包括给予三环杂环化合物。 本发明的化合物，组合物和方法也可用于抑制癌细胞或肿瘤细胞的生长，治疗或预防病毒感染，或抑制病毒的复制和/或感染性。
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公开(公告)号：US08420638B2
公开(公告)日：2013-04-16
申请号：US13171891
申请日：2011-06-29
IPC分类号： A61K31/535 , A61K31/44 , A61K31/42 , A61K31/40 , A61K31/49 , C07D209/14
CPC分类号： C07D403/14 , C07D403/04 , C07D405/14 , C07D409/14 , C07D413/14 , C07D491/04 , C07F9/65583
摘要： The present invention relates to novel Triheterocyclic Compounds, compositions comprising a Triheterocyclic Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering a Triheterocyclic Compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell, treating or preventing a viral infection, or inhibiting the replication and/or infectivity of a virus.
摘要翻译： 本发明涉及新颖的三杂环化合物，包含三杂环化合物的组合物，以及可用于治疗或预防癌症或肿瘤性疾病的方法，包括给予三环杂环化合物。 本发明的化合物，组合物和方法也可用于抑制癌细胞或肿瘤细胞的生长，治疗或预防病毒感染，或抑制病毒的复制和/或感染性。
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8.发明授权Diterpenoid compounds, compositions thereof and their use as anti-cancer or anti-fungal agents 失效二萜类化合物，其组合物及其作为抗癌剂或抗真菌剂的用途公开(公告)号：US07217844B2
公开(公告)日：2007-05-15
申请号：US10725629
申请日：2003-12-01
申请人： Pierre Beauparlant , Giorgio Attardo , Zhiying Zhang , Angela M. Stafford , Rosa Ubillas , James B. McAlpine , Jean-Francois Lavallee , Samuel Fortin , Sasmita Tripathy
发明人： Pierre Beauparlant , Giorgio Attardo , Zhiying Zhang , Angela M. Stafford , Rosa Ubillas , James B. McAlpine , Jean-Francois Lavallee , Samuel Fortin , Sasmita Tripathy
IPC分类号： C07C43/162 , C07C43/164 , C07C43/166 , C07C49/225 , C07D237/36 , C07D239/70 , A61K31/53 , A61K31/519 , A61K31/498 , A61K31/473 , A61P35/00
CPC分类号： C07C69/757 , C07C45/292 , C07C49/755 , C07C2603/26
摘要： The present invention relates to Diterpenoid Compounds, compositions comprising an effective amount of a Diterpenoid Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering an effective amount of a Diterpenoid Compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell, or for inducing apoptosis in a cancer or neoplastic cell. The compounds, compositions, and methods of the invention are further useful for treating or preventing a fungal infection. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a fungus.
摘要翻译： 本发明涉及二萜化合物，包含有效量的二萜化合物的组合物和可用于治疗或预防癌症或肿瘤性疾病的方法，其包括施用有效量的二萜化合物。 本发明的化合物，组合物和方法也可用于抑制癌细胞或肿瘤细胞的生长，或用于诱导癌症或肿瘤细胞中的凋亡。 本发明的化合物，组合物和方法还可用于治疗或预防真菌感染。 本发明的化合物，组合物和方法也可用于抑制真菌的生长。
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公开(公告)号：US20120004224A1
公开(公告)日：2012-01-05
申请号：US13171891
申请日：2011-06-29
IPC分类号： A61K31/5377 , A61K31/496 , A61P31/12 , A61K31/422 , A61K31/407 , A61P35/00 , A61K31/404 , A61K31/4439
CPC分类号： C07D403/14 , C07D403/04 , C07D405/14 , C07D409/14 , C07D413/14 , C07D491/04 , C07F9/65583
摘要： The present invention relates to novel Triheterocyclic Compounds, compositions comprising a Triheterocyclic Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering a Triheterocyclic Compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell, treating or preventing a viral infection, or inhibiting the replication and/or infectivity of a virus.
摘要翻译： 本发明涉及新颖的三杂环化合物，包含三杂环化合物的组合物，以及可用于治疗或预防癌症或肿瘤性疾病的方法，包括给予三环杂环化合物。 本发明的化合物，组合物和方法也可用于抑制癌细胞或肿瘤细胞的生长，治疗或预防病毒感染，或抑制病毒的复制和/或感染性。
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10.发明申请Diterpenoid compounds, compositions thereof and their use as anti-cancer or anti-fungal agents 失效二萜类化合物，其组合物及其作为抗癌剂或抗真菌剂的用途公开(公告)号：US20050070540A1
公开(公告)日：2005-03-31
申请号：US10725629
申请日：2003-12-01
申请人： Pierre Beauparlant , Giorgio Attardo , Zhiying Zhang , Angela Stafford , Rosa Ubillas , James McAlpine , Jean-Francois Lavallee , Samuel Fortin , Sasmita Tripathy
发明人： Pierre Beauparlant , Giorgio Attardo , Zhiying Zhang , Angela Stafford , Rosa Ubillas , James McAlpine , Jean-Francois Lavallee , Samuel Fortin , Sasmita Tripathy
IPC分类号： A61P35/00 , C07C45/29 , C07C49/755 , C07C69/00 , A61K31/53 , A61K31/473 , A61K31/498 , A61K31/519
CPC分类号： C07C69/757 , C07C45/292 , C07C49/755 , C07C2603/26
摘要： The present invention relates to Diterpenoid Compounds, compositions comprising an effective amount of a Diterpenoid Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering an effective amount of a Diterpenoid Compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell, or for inducing apoptosis in a cancer or neoplastic cell. The compounds, compositions, and methods of the invention are further useful for treating or preventing a fungal infection. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a fungus.
摘要翻译： 本发明涉及二萜化合物，包含有效量的二萜化合物的组合物和可用于治疗或预防癌症或肿瘤性疾病的方法，其包括施用有效量的二萜化合物。 本发明的化合物，组合物和方法也可用于抑制癌细胞或肿瘤细胞的生长，或用于诱导癌症或肿瘤细胞中的凋亡。 本发明的化合物，组合物和方法还可用于治疗或预防真菌感染。 本发明的化合物，组合物和方法也可用于抑制真菌的生长。
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