Fusion proteins of Mycobacterium tuberculosis
    3.
    发明授权
    Fusion proteins of Mycobacterium tuberculosis 有权
    结核分枝杆菌的融合蛋白

    公开(公告)号:US08110200B2

    公开(公告)日:2012-02-07

    申请号:US12698893

    申请日:2010-02-02

    IPC分类号: A61K39/04 A61K39/02 A61K39/00

    摘要: The present invention relates to compositions and fusion proteins containing at least two Mycobacterium sp. antigens, and nucleic acids encoding such compositions and fusion proteins. The compositions of the invention increase serological sensitivity of sera from individuals infected with tuberculosis, and methods for their use in the diagnosis, treatment, and prevention of tuberculosis infection.

    摘要翻译: 本发明涉及含有至少两种分枝杆菌属的组合物和融合蛋白。 抗原和编码这些组合物的核酸和融合蛋白。 本发明的组合物增加来自感染结核病的个体的血清的血清学敏感性,以及用于诊断,治疗和预防结核病感染的方法。