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1.发明申请公开(公告)号：US20080046037A1
公开(公告)日：2008-02-21
申请号：US11739283
申请日：2007-04-24
IPC分类号： A61N1/02
CPC分类号： H04B13/005 , A61B5/0028 , A61B5/0031 , A61N1/08 , A61N1/37211 , A61N1/37217 , G06F19/3418 , H04L25/03114 , H04L2025/03375 , H04L2025/0377
摘要： An implantable medical device system includes, in one embodiment, a first device including a first communication module coupled to a wireless communication network for transmitting data and a second device adapted for implantation in a patient's body including a second communication module coupled to the wireless communication network and adapted to receive data from the first device. The second device may include an equalizer coupled to the second communication module for reducing signal distortion of the data received wirelessly through the patient's body. The second device may convert a received signal to an acoustic or radio-frequency output signal.
摘要翻译： 在一个实施例中，可植入医疗装置系统包括第一装置，其包括耦合到用于传输数据的无线通信网络的第一通信模块和适于植入患者体内的第二装置，其包括耦合到无线通信网络的第二通信模块 并适于从第一设备接收数据。 第二设备可以包括耦合到第二通信模块的均衡器，用于减少通过患者身体无线地接收的数据的信号失真。 第二装置可以将接收的信号转换成声或射频输出信号。
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2.发明申请LOCAL COMMUNICATIONS NETWORK FOR DISTRIBUTED SENSING AND THERAPY IN BIOMEDICAL APPLICATIONS 审中-公开生物医学应用中分布式感知和治疗的本地通信网络公开(公告)号：US20080046038A1
公开(公告)日：2008-02-21
申请号：US11739434
申请日：2007-04-24
IPC分类号： A61N1/02
CPC分类号： A61N1/37288 , A61B5/0031 , A61B2560/0209 , A61M5/14276 , A61M2205/3523 , A61M2205/3569 , A61M2205/8212 , A61M2209/01 , A61N1/37276 , A61N1/39
摘要： A local communication network for an implantable medical device system is provided. The system includes a first medical device and a second medical device adapted for implantation in the body of a patient including a telemetry circuit enabled for transmitting data via a wireless communication link to the first medical device. The system further includes a third device comprising signal generating circuitry for generating a wake-up signal. The second implantable medical device transitions from an “off” state to a high-power “on” state in response to the wake-up signal generated by the third device.
摘要翻译： 提供了一种用于植入式医疗装置系统的本地通信网络。 该系统包括适于植入患者体内的第一医疗设备和第二医疗设备，包括能够经由无线通信链路向第一医疗设备发送数据的遥测电路。 该系统还包括第三装置，其包括用于产生唤醒信号的信号发生电路。 第二可植入医疗装置响应于由第三装置产生的唤醒信号从“关闭”状态转换到大功率“开”状态。
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3.发明授权Heart monitoring systems, apparatus and methods adapted to detect myocardial ischemia 有权适用于检测心肌缺血的心脏监测系统，装置和方法公开(公告)号：US09179852B2
公开(公告)日：2015-11-10
申请号：US11684794
申请日：2007-03-12
IPC分类号： A61B5/04 , A61B5/0452 , A61B5/0402 , A61B5/00
CPC分类号： A61B5/0452 , A61B5/0006 , A61B5/0031 , A61B5/0402 , A61B5/721 , A61B5/7475
摘要： Embodiments include heart monitoring systems, apparatus, and methods adapted to detect myocardial ischemia. An apparatus includes at least one first-tier sensor/analyzer adapted to sense a first input related to cardiac function, and to produce a first-tier trigger signal when the first input indicates myocardial ischemia. In an embodiment, a first-tier sensor/analyzer includes an ECG sensor/analyzer. In another embodiment, a first-tier sensor/analyzer includes a patient activator. An apparatus further includes at least one second-tier sensor/analyzer adapted to sense a second input related to cardiac function, and to produce a second-tier trigger signal when the second input indicates myocardial ischemia. In an embodiment, a second-tier sensor-analyzer includes a heart sound sensor/analyzer. A triggering element is adapted to produce a response-invoking signal in response to the first-tier trigger signal and the second-tier trigger signal. The response-invoking signal may invoke a patient alert, a message to an external system, and/or a cardiac stimulus.
摘要翻译： 实施例包括适于检测心肌缺血的心脏监测系统，装置和方法。 一种装置包括适于感测与心脏功能相关的第一输入的至少一个第一层传感器/分析器，以及当第一输入指示心肌缺血时产生第一层触发信号。 在一个实施例中，第一层传感器/分析器包括ECG传感器/分析器。 在另一个实施例中，第一层传感器/分析器包括患者激活器。 装置还包括适于感测与心脏功能相关的第二输入的至少一个第二层传感器/分析器，并且当第二输入指示心肌缺血时产生第二层触发信号。 在一个实施例中，第二层传感器分析仪包括心音传感器/分析器。 触发元件适于响应于第一层触发信号和第二层触发信号产生响应调用信号。 响应调用信号可以调用患者警报，到外部系统的消息和/或心脏刺激。
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公开(公告)号：US07594889B2
公开(公告)日：2009-09-29
申请号：US11097685
申请日：2005-03-31
申请人： John W. St. Ores , Sarah A. Audet , James K. Carney , Janell M. Gottesman , Adrianus P. Donders , Michael R. Ujhelyi
发明人： John W. St. Ores , Sarah A. Audet , James K. Carney , Janell M. Gottesman , Adrianus P. Donders , Michael R. Ujhelyi
IPC分类号： A61B1/00
CPC分类号： A61B5/0031 , G06F19/00 , G06Q40/08 , G16H10/20
摘要： A data collection system includes remote, implantable sensors for monitoring one or more patient parameters, collecting and processing data from those sensors and utilizing that data in the performance of a clinical study of a drug or other pharmacological agent. The system assists with preparation of a protocol for a clinical trial; presentation of that protocol; assuring compliance with the protocol; and generating useful results from data collected via the system and externally for presentation to an approval forum.
摘要翻译： 数据收集系统包括用于监测一个或多个患者参数的远程可植入传感器，收集和处理来自那些传感器的数据并利用该数据来执行药物或其他药理学试剂的临床研究。 该系统协助制定临床试验方案; 该协议的呈现; 确保遵守协议; 并从通过系统收集的数据和外部产生有用的结果，以呈现给审批论坛。
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公开(公告)号：US09301698B2
公开(公告)日：2016-04-05
申请号：US12263423
申请日：2008-10-31
申请人： Sarah A. Audet , James K. Carney , William J. Combs , Tommy D. Bennett , Barbro M. L. Kjellstrom
发明人： Sarah A. Audet , James K. Carney , William J. Combs , Tommy D. Bennett , Barbro M. L. Kjellstrom
IPC分类号： A61B5/0215 , A61N1/365 , A61N1/372 , A61B5/00
CPC分类号： A61B5/02055 , A61B5/0215 , A61B5/4836 , A61B5/686 , A61B5/7203 , A61N1/36514 , A61N1/36564 , A61N1/37258
摘要： The present disclosure provides an apparatus and method of detecting ischemia with a pressure sensor. The method can include obtaining a pressure signal and determining a pressure rate of change. The method can also include identifying at least one of impaired relaxation and impaired contractility in order to detect ischemia.
摘要翻译： 本公开提供了利用压力传感器检测缺血的装置和方法。 该方法可以包括获得压力信号并确定压力变化率。 该方法还可以包括鉴定减轻的松弛和受损的收缩力中的至少一种以便检测缺血。
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6.发明申请Heart Monitoring Systems, Apparatus and Methods Adapted to Detect Myocardial Ischemia 有权心脏监测系统，适用于检测心肌缺血的装置和方法公开(公告)号：US20080228094A1
公开(公告)日：2008-09-18
申请号：US11684794
申请日：2007-03-12
IPC分类号： A61B5/04
CPC分类号： A61B5/0452 , A61B5/0006 , A61B5/0031 , A61B5/0402 , A61B5/721 , A61B5/7475
摘要： Embodiments include heart monitoring systems, apparatus, and methods adapted to detect myocardial ischemia. An apparatus includes at least one first-tier sensor/analyzer adapted to sense a first input related to cardiac function, and to produce a first-tier trigger signal when the first input indicates myocardial ischemia. In an embodiment, a first-tier sensor/analyzer includes an ECG sensor/analyzer. In another embodiment, a first-tier sensor/analyzer includes a patient activator. An apparatus further includes at least one second-tier sensor/analyzer adapted to sense a second input related to cardiac function, and to produce a second-tier trigger signal when the second input indicates myocardial ischemia. In an embodiment, a second-tier sensor-analyzer includes a heart sound sensor/analyzer. A triggering element is adapted to produce a response-invoking signal in response to the first-tier trigger signal and the second-tier trigger signal. The response-invoking signal may invoke a patient alert, a message to an external system, and/or a cardiac stimulus.
摘要翻译： 实施例包括适于检测心肌缺血的心脏监测系统，装置和方法。 一种装置包括适于感测与心脏功能相关的第一输入的至少一个第一层传感器/分析器，以及当第一输入指示心肌缺血时产生第一层触发信号。 在一个实施例中，第一层传感器/分析器包括ECG传感器/分析器。 在另一个实施例中，第一层传感器/分析器包括患者激活器。 装置还包括适于感测与心脏功能相关的第二输入的至少一个第二层传感器/分析器，并且当第二输入指示心肌缺血时产生第二层触发信号。 在一个实施例中，第二层传感器分析仪包括心音传感器/分析器。 触发元件适于响应于第一层触发信号和第二层触发信号产生响应调用信号。 响应调用信号可以调用患者警报，到外部系统的消息和/或心脏刺激。
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7.发明授权Semiconductor device comprising a silicide layer, and method of making the device 失效包括硅化物层的半导体器件及其制造方法
公开(公告)号：US5122479A
公开(公告)日：1992-06-16
申请号：US683891
申请日：1991-04-11
IPC分类号： H01L21/28 , H01L21/265 , H01L21/285
CPC分类号： H01L21/28518 , H01L21/26506 , Y10S148/003
摘要： Disclosed is a method of making a Si-based semiconductor device comprising a contact region that comprises a thin (exemplarily less than 50 nm), substantially uniform silicide layer. The silicide preferably is CoSi.sub.2 or TiSi.sub.2. The method comprises implantation of the appropriate metal ions into a Si body, the dose and the body temperature selected such that substantially complete amorphization of the implant volume results. Subsequently, the Si body is subjected to an annealing treatment that results in recrystallization of the implant volume and formation of the silicide layer. The layer extends to the surface of the body and contains essentially all of the implanted metal ions. The invention can advantageously be used in conjunction with extremely shallow junctions, such as will be of interest in short (e.g.,
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