摘要:
Various embodiments of a capsule polishing device include a resistive-heating element including an electrically resistive, superelastic wire forming a loop between first and second ends of the superelastic wire. The first and second ends of the loop may at least partially extend from a planar face defined by the loop, to an insulating portion. In some embodiments, the capsule polishing device may be configured to perform active capsule polishing through a combination of hyperthermia of LECs and mechanical abrasion of the capsule surface. In some embodiments, at least a side and end portion of the loop of the capsule polishing device may be shaped to follow a contour of the capsule bag. The loop may be heated to approximately 40 to 47 degrees Celsius to destroy LECs (other temperatures are also possible). In some embodiments, the loop may include a roughened surface to increase mechanical abrasion.
摘要:
Various embodiments of a capsularhexis device include a resistive-heating element comprising an electrically resistive, superelastic wire forming a loop between first and second ends of the superelastic wire. The loop may be retracted into a collapsed, retracted position or ejected into an expanded position. The first and second ends of the loop may at least partially extend at an angle from a planar face defined by the loop, to the insulating portion, to form a transitional neck between the loop and the insulating portion. The transitional neck may have a gap between the first and second ends at the insulating portion that is wider than a gap between the first and second ends on the opposing side of the transitional neck. The gap in the loop of superelastic wire may be sufficiently small to allow the loop to form a continuous cut in a capsule of an eye.
摘要:
Various embodiments of a capsulotomy repair device include a resistive-heating element comprising an electrically resistive, superelastic wire forming a loop between first and second ends of the superelastic wire. The first and second ends of the loop may at least partially extend at an angle from a planar face defined by the loop, to an insulating portion, to form a transitional neck between the loop and the insulating portion. The capsulotomy repair device may be positioned in the eye relative to a capsularhexis perimeter to overlap tears in the capsularhexis periemeter to remove the tears by forming an adjusted capsularhexis perimeter by burning around the tear.
摘要:
Various embodiments of a capsulotomy repair device include a resistive-heating element comprising an electrically resistive, superelastic wire forming a loop between first and second ends of the superelastic wire. The first and second ends of the loop may at least partially extend at an angle from a planar face defined by the loop, to an insulating portion, to form a transitional neck between the loop and the insulating portion. The capsulotomy repair device may be positioned in the eye relative to a capsularhexis perimeter to overlap tears in the capsularhexis perimeter to remove the tears by forming an adjusted capsularhexis perimeter by burning around the tear.
摘要:
Various embodiments of a capsule polishing device include a resistive-heating element including an electrically resistive, superelastic wire forming a loop between first and second ends of the superelastic wire. The first and second ends of the loop may at least partially extend from a planar face defined by the loop, to an insulating portion. In some embodiments, the capsule polishing device may be configured to perform active capsule polishing through a combination of hyperthermia of LECs and mechanical abrasion of the capsule surface. In some embodiments, at least a side and end portion of the loop of the capsule polishing device may be shaped to follow a contour of the capsule bag. The loop may be heated to approximately 40 to 47 degrees Celsius to destroy LECs (other temperatures are also possible). In some embodiments, the loop may include a roughened surface to increase mechanical abrasion.
摘要:
An ablation probe for use in glaucoma surgery has a shaft, a heating element, and a pair of electrical connectors located on a distal end of the shaft. The pair of electrical connectors holds the heating element to the shaft. The heating element is sized and shaped to ablate a trabecular meshwork in a human eye. The ablation probe is advanced through a corneal incision until the heating element contacts the trabecular meshwork. An electrical current is passed through the heating element to ablate the trabecular meshwork.
摘要:
A capsularhexis electrode device and corresponding insertion tool are disclosed. A flexible capsulorhexis electrode device comprises an elastomeric ring, first and second electrically conductive traces disposed at a first face of the elastomeric ring and extending concentrically around the elastomeric ring, and first and second electrically conductive connectors. The first and second electrically conductive connectors are electrically connected to the first and second traces, respectively, and are disposed at opposing points across the elastomeric ring from one another. An insertion tool includes first and second stretcher bars with connectors for mating to the electrode device. One of the stretcher bars translates relative to the other to elongate the flexible electrode device for insertion into the anterior chamber of the eye through a small incision.
摘要:
A microfluidic switching device includes a planar substrate having a central axis of rotation and a radially-oriented microchannel disposed in the planar substrate that terminates at a junction. In one aspect, the junction is formed as a double-layered junction in which an upstream portion is vertically offset from a downstream portion. In addition, the upstream portion has a smaller effective center of cross-sectional area than the downstream portion. First and rotation second outlet chambers are coupled at one end to the junction. The device is rotated about the central axis in a clockwise direction so as to cause the fluid in the reservoir to flow into the first (right) outlet chamber or in a counter-clockwise direction so as to cause the fluid in the reservoir to flow into the second (left) outlet chamber.
摘要:
A microfluidic device for the splitting or sequencing of fluid flow includes a plurality of upstream and/or downstream chambers coupled via microfluidic channels. For splitting fluid, a substrate is provided that includes a main chamber and a plurality of downstream sub-chambers. Each sub-chamber is associated with a sealable vent hole. Fluid is selectively moved into the desired sub-chamber of interest by unsealing its associated vent hole. Fluid is then pumped into the sub-chamber, for example, by rotating the substrate. For flow sequencing, a substrate is provided that includes a plurality of upstream chambers coupled to at least one downstream chamber. Each upstream chamber has an associated vent hole that can be selectively opened. The substrate is then rotated and fluid contained in the upstream chamber with the valve in the unsealed state will then pass to the at least one downstream chamber.
摘要:
C-MEMS architecture having high aspect ratio carbon structures and improved systems and methods for producing high aspect ratio C-MEMS structures are provided. Specifically, high aspect ratio carbon structures are microfabricated by pyrolyzing a patterned carbon precursor polymer. Pyrolysing the polymer preferably comprises a multi-step process in an atmosphere of inert and forming gas at high temperatures that trail the glass transit temperature (Tg) for the polymer. Multi-layer C-MEMS carbon structures are formed from multiple layers of negative photoresist, wherein a first layer forms carbon interconnects and the second and successive layers form high aspect ratio carbon structures. High-conductivity interconnect traces to connect C-MEMS carbon structures are formed by depositing a metal layer on a substrate, patterning a polymer precursor on top of the metal layer and pyrolyzing the polymer to create the final structure. The interconnects of a device with high aspect ratio electrodes are insulated using a self aligning insulation method.