公开(公告)号：US20050251218A1

公开(公告)日：2005-11-10

申请号：US10945639

申请日：2004-09-21

申请人： H. Markowitz ,  Pooja Mehta ,  Chad Giese ,  Mark Erickson ,  Yong Cho ,  Marina Jovanovic ,  Sameh Sowelam

发明人： H. Markowitz ,  Pooja Mehta ,  Chad Giese ,  Mark Erickson ,  Yong Cho ,  Marina Jovanovic ,  Sameh Sowelam

IPC分类号： A61N1/18 ,  A61N1/20 ,  A61N1/22 ,  A61N1/34 ,  A61N1/36 ,  A61N1/362 ,  A61N1/365 ,  A61N1/39

CPC分类号： A61N1/3601 ,  A61N1/36557 ,  A61N1/3962

摘要： Oxygen saturation data is monitored during a predefined window to obtain a measurement of circulation delay. The measured circulation delay is used as a basis for determining therapies, including overdrive pacing. In some embodiments, circulation delay is used to identify patients that will benefit from overdrive pacing as a therapy for sleep disordered breathing.

摘要翻译： 在预定窗口期间监测氧饱和度数据，以获得循环延迟的测量。 测量的循环延迟被用作确定治疗的基础，包括超速起搏。 在一些实施例中，循环延迟用于识别将受益于过度起搏起搏作为睡眠无序呼吸治疗的患者。

公开(公告)号：US20050119711A1

公开(公告)日：2005-06-02

申请号：US10419404

申请日：2003-04-21

申请人： Yong Cho ,  Abed Lawabni ,  Todd Sheldon ,  H. Markowitz ,  Sameh Sowelam ,  Raylene Pitschneider

发明人： Yong Cho ,  Abed Lawabni ,  Todd Sheldon ,  H. Markowitz ,  Sameh Sowelam ,  Raylene Pitschneider

IPC分类号： A61B5/0205 ,  A61B5/08 ,  A61N1/18

CPC分类号： A61B5/4818 ,  A61B5/0205 ,  A61B5/0809 ,  A61B5/0816 ,  G06F19/00

摘要： The present invention relates to a device and method for monitoring for sleep disordered breathing or other types of disordered breathing such as Cheyne-Stokes breathing. More specifically, a device and method for detecting disordered breathing is provided that monitors a physiological parameter, which becomes cyclical due to apnea-hyperpnea (or arousal) alternation and provides the basis for the determination of a number of breathing disorder metrics.

摘要翻译： 本发明涉及一种用于监测睡眠呼吸紊乱或其他类型无序呼吸（例如Cheyne-Stokes呼吸）的装置和方法。 更具体地，提供了一种用于检测无序呼吸的装置和方法，其监测由于呼吸暂停呼吸（或唤醒）交替而变得周期性的生理参数，并且提供了确定多个呼吸障碍度量的基础。

公开(公告)号：US20070167843A1

公开(公告)日：2007-07-19

申请号：US11565092

申请日：2006-11-30

申请人： Yong Cho ,  Steven Lu ,  Luc Mongeon ,  Scott Davie ,  Todd Sheldon ,  Mark Erickson ,  H. Markowitz

发明人： Yong Cho ,  Steven Lu ,  Luc Mongeon ,  Scott Davie ,  Todd Sheldon ,  Mark Erickson ,  H. Markowitz

IPC分类号： A61B5/02 ,  A61B5/08

CPC分类号： A61B5/0809 ,  A61B5/0205 ,  A61B5/0215 ,  A61B5/0402 ,  A61B5/1459 ,  A61B5/4818 ,  G06F19/00

摘要： A system and method for monitoring respiration including sensing a signal that varies with respiration, deriving a respiration parameter, applying criteria for detecting a respiration disturbance and determining one or more respiratory disturbance metrics. The system preferably includes an implantable sensor with an associated implantable medical device such that chronic respiration monitoring is possible. The implantable medical device may execute methods for detecting and measuring respiratory disturbances or may store data to be transferred to an external device for detecting and measuring respiratory disturbances. Respiratory disturbance detection may trigger a responsive action such as physiological data storage, a change in therapy delivery, or a clinician warning. Assessment of cardiac function may be made based on metrics of respiratory disturbances or a measure of circulatory delay time following detection of a respiratory disturbance.

摘要翻译： 一种用于监测呼吸的系统和方法，包括感测随呼吸变化的信号，导出呼吸参数，应用用于检测呼吸障碍的标准和确定一个或多个呼吸障碍度量。 该系统优选地包括具有相关联的可植入医疗装置的可植入传感器，使得可以进行慢性呼吸监测。 可植入医疗装置可以执行用于检测和测量呼吸障碍的方法，或者可以将要传送到外部设备的数据存储以检测和测量呼吸障碍。 呼吸道干扰检测可能会触发响应动作，如生理数据存储，治疗传递的变化或临床医生的警告。 心脏功能的评估可以基于呼吸紊乱的度量或检测到呼吸障碍之后的循环延迟时间的量度进行。

公开(公告)号：US20050203579A1

公开(公告)日：2005-09-15

申请号：US10799260

申请日：2004-03-12

申请人： Sameh Sowelam ,  Todd Sheldon ,  Yong Cho

发明人： Sameh Sowelam ,  Todd Sheldon ,  Yong Cho

IPC分类号： A61B5/103 ,  A61N1/362 ,  A61N1/365 ,  A61N1/368 ,  A61N1/18 ,  A61N1/20 ,  A61N1/22

CPC分类号： A61N1/368 ,  A61N1/3627 ,  A61N1/36521 ,  A61N1/3684

摘要： A system and automated method for assessing ventricular synchrony in ambulatory patients is provided including at least one mechanical sensor (e.g., accelerometer, tensiometric sensor, force transducer, and the like) operatively coupled to a first myocardial location in order to measure a wall motion signal of a first chamber, and a second mechanical sensor operatively coupled to a second myocardial location in order to measure a wall motion signal of a second chamber. The wall motion signals are processed in order to identify the time at which a fiducial (e.g., an inflection point, a threshold crossing, a maximum amplitude, etc.) occurs for each respective signal. The temporal separation between the fiducial points on each respective signal is measured as a metric of ventricular synchrony and can be optionally utilized to adjust pacing therapy timing to improve synchrony.

摘要翻译： 提供了一种用于评估移动患者的心室同步的系统和自动化方法，其包括至少一个可操作地耦合到第一心肌位置的机械传感器（例如，加速度计，张力传感器，力换能器等），以便测量壁运动信号 以及可操作地耦合到第二心肌位置的第二机械传感器，以便测量第二腔室的壁运动信号。 对墙壁运动信号进行处理，以便识别针对每个相应信号发生基准（例如，拐点，阈值交叉，最大振幅等）的时间。 每个相应信号上的基准点之间的时间间隔被测量为心室同步的度量，并且可以可选地用于调整起搏治疗定时以改善同步。

公开(公告)号：US20050090871A1

公开(公告)日：2005-04-28

申请号：US10693375

申请日：2003-10-24

申请人： Yong Cho ,  H. Markowitz

发明人： Yong Cho ,  H. Markowitz

IPC分类号： A61B5/08 ,  A61N1/36 ,  A61N1/362 ,  A61N1/365

CPC分类号： A61N1/3601 ,  A61B5/08 ,  A61B5/082 ,  A61N1/36521 ,  A61N1/36557

摘要： An implantable medical device delivers augmentation therapy to intervene in a pattern of sleep-disordered breathing. Augmentation therapy includes the delivery of electrical stimulation to cardiac tissue above and/or below a capture threshold. PESP and NES/CCM are possible augmentation therapies that are used alone or in combination. In addition, augmentation therapies can be used with other pacing therapies such as atrial overdrive pacing and atrial coordinated pacing as a therapy for sleep-disordered breathing.

摘要翻译： 可植入的医疗装置提供增强疗法以介入睡眠呼吸障碍的模式。 增强疗法包括将电刺激递送到高于和/或低于捕获阈值的心脏组织。 PESP和NES / CCM是单独使用或组合使用的可能的增强疗法。 此外，增强疗法可以与其他起搏疗法一起使用，例如心房超速起搏和心房协调起搏作为睡眠呼吸障碍的治疗方法。

公开(公告)号：US08793223B1

公开(公告)日：2014-07-29

申请号：US12368158

申请日：2009-02-09

申请人： Yong Cho ,  Maya Palem ,  Vignesh Sukumar ,  John K. Edwards ,  David Grunwald ,  Andy Kahn

发明人： Yong Cho ,  Maya Palem ,  Vignesh Sukumar ,  John K. Edwards ,  David Grunwald ,  Andy Kahn

IPC分类号： G06F17/30

CPC分类号： G06F11/1076 ,  G06F17/3007 ,  H04L67/1097

摘要： A network storage server includes a tool for detecting and fixing errors while the network storage server remains online (available for servicing client requests), which includes enabling a user to approve or disapprove remedial changes before the changes are committed. The technique bypasses the usual consistency point process for new or modified data blocks representing potential remedial changes. At a consistency point, dirty data blocks representing the potential remedial changes are written to a change log file residing outside the volume. The modified data blocks are written in sequential order to logical blocks of the change log file. In response to a user input indicating that a potential change should be committed, the corresponding modified data blocks are read from the change log file in the order in which they were written to the change log file, and they are written to persistent storage in that order.

摘要翻译： 网络存储服务器包括用于在网络存储服务器保持联机（可用于服务客户端请求）的情况下检测和修复错误的工具，其中包括使用户在更改发生之前批准或不批准补救更改。 该技术绕过代表潜在补救变化的新的或修改的数据块的通常一致性点过程。 在一致性点上，将表示潜在补救措施更改的脏数据块写入驻留在卷外的更改日志文件。 经修改的数据块按顺序写入变更日志文件的逻辑块。 响应于指示应该提交潜在变化的用户输入，从更改日志文件中读取相应的修改后的数据块，并将它们写入到更改日志文件中，并将它们写入永久存储器 订购。

公开(公告)号：US07438829B2

公开(公告)日：2008-10-21

申请号：US10712670

申请日：2003-11-13

申请人： Yong Cho ,  Terri Cardellino ,  James Daniel Tremel

发明人： Yong Cho ,  Terri Cardellino ,  James Daniel Tremel

IPC分类号： H01J1/56 ,  H01J35/20 ,  H01J7/18 ,  C03C8/02 ,  C03C8/16

CPC分类号： B01J20/183 ,  B01D53/261 ,  H01L51/5259

摘要： The invention is directed to a screen-printable getter composition comprising: (a) glass frit; dispersed in (b) organic medium. The invention is further directed to a screen-printable thick film getter composition comprising: (a) glass frit; and (b) desiccant material; dispersed in (c) organic medium.The present invention further relates to a getter composition utilizing low-softening temperature glasses comprising, based on weight %, 1-50% SiO2, 0-80% B2O3, 0-90% Bi2O3, 0-90% PbO, 0-90% P2O5, 0-60% Li2O, 0-30% Al2O3, 0-10% K2O, 0-10% Na2O, and 0-30% MO where M is selected from Ba, Sr, Ca, Zn, Cu, Mg and mixtures thereof. The glasses described herein may contain several other oxide constituents that can substitute glass network-forming elements or modify glass structure.

摘要翻译： 本发明涉及一种可丝网印刷的吸气剂组合物，其包括：（a）玻璃料; 分散在（b）有机介质中。 本发明还涉及一种可丝网印刷的厚膜吸气剂组合物，其包含：（a）玻璃料; 和（b）干燥剂材料; 分散在（c）有机介质中。 本发明还涉及一种使用低软化温度玻璃的吸气剂组合物，其基于重量百分比为1-50％SiO 2，0-80％B 2 O 0〜90％的Bi 2 O 3，0〜90％的PbO，0〜90％的P 2

公开(公告)号：US20070190733A1

公开(公告)日：2007-08-16

申请号：US11733430

申请日：2007-04-10

申请人： Yong Cho

发明人： Yong Cho

IPC分类号： H01L21/336

CPC分类号： H01L29/66606 ,  H01L21/28114 ,  H01L29/105 ,  H01L29/665 ,  H01L29/66545 ,  H01L29/66553 ,  H01L29/66628

摘要： Transistors and methods of fabricating transistors are disclosed. A disclosed method comprises forming an inversion epitaxial layer on a silicon substrate; forming a hard mask on the inversion epitaxial layer; depositing a silicon epitaxial layer over the inversion epitaxial layer; forming a trench through the silicon epitaxial layer by removing the hard mask; forming reverse spacers on the sidewalls of the trench by filling the trench with an insulating layer and etching the insulating layer; forming a gate electrode over the reverse spacers; forming pocket-well regions and LDD regions in the silicon substrate by performing ion implantations; forming spacers on the sidewalls of the gate electrode; forming source and drain regions in the silicon substrate by performing an ion implantation; and forming a silicide layer on the gate electrode and the source and drain regions.

摘要翻译： 公开了制造晶体管的晶体管和方法。 所公开的方法包括在硅衬底上形成反转外延层; 在反转外延层上形成硬掩模; 在所述反转外延层上沉积硅外延层; 通过去除硬掩模，通过硅外延层形成沟槽; 通过用绝缘层填充沟槽并蚀刻绝缘层，在沟槽的侧壁上形成反向间隔物; 在所述反向间隔物上形成栅电极; 通过进行离子注入在硅衬底中形成口袋区域和LDD区域; 在栅电极的侧壁上形成间隔物; 通过进行离子注入在硅衬底中形成源区和漏区; 以及在栅电极和源极和漏极区上形成硅化物层。

公开(公告)号：US20070156057A1

公开(公告)日：2007-07-05

申请号：US11323895

申请日：2005-12-30

申请人： Yong Cho ,  Yongduk Cho ,  Tommy Bennett

发明人： Yong Cho ,  Yongduk Cho ,  Tommy Bennett

IPC分类号： A61B5/04

CPC分类号： A61N1/3702 ,  A61N1/36535 ,  A61N1/36542

摘要： Systems and methods for improving hemodynamic data interpretation by accounting for the effects of patient posture is disclosed. In certain embodiments, a posture signal is acquired and used to categorize hemodynamic data according to posture to facilitate distinguishing posture-related changes in acquired hemodynamic data from those due to pathophysiologic changes. Posture information may be used to normalize data acquired in various postures to facilitate interpretation of such data. Baseline measurements of hemodynamic data acquired in various postures may also be used to subsequently detect changes in patient posture without the need for an implanted posture sensor.

摘要翻译： 公开了通过考虑患者姿势的影响来改善血液动力学数据解释的系统和方法。 在某些实施例中，获取姿势信号并用于根据姿势对血液动力学数据进行分类，以便于将所获得的血液动力学数据中的姿势相关变化与由于病理生理变化引起的姿势相关的变化区分开。 姿势信息可以用于对在各种姿势中获取的数据进行归一化，以便于解释这些数据。 在各种姿势中获取的血液动力学数据的基线测量也可用于随后检测患者姿势的变化，而不需要植入的姿势传感器。

公开(公告)号：US20070124341A1

公开(公告)日：2007-05-31

申请号：US11409626

申请日：2006-04-24

申请人： Jason Lango ,  Yong Cho ,  Paul Eastham ,  Ling Zheng ,  Stephen Manley ,  John Edwards ,  Robert English ,  Emmanuel Ackaouy

发明人： Jason Lango ,  Yong Cho ,  Paul Eastham ,  Ling Zheng ,  Stephen Manley ,  John Edwards ,  Robert English ,  Emmanuel Ackaouy

IPC分类号： G06F17/30

CPC分类号： G06F17/30067

摘要： A technique is disclosed for restoring data of sparse volumes, where one or more block pointers within the file system structure are marked as ABSENT, and fetching the appropriate data from an alternate location on demand. Client data access requests to the local storage system initiate a restoration of the data from a backing store as required. A demand generator can also be used to restore the data as a background process by walking through the sparse volume and restoring the data of absent blocks. A pump module is also disclosed to regulate the access of the demand generator. Once all the data has been restored, the volume contains all data locally, and is no longer a sparse volume.

摘要翻译： 公开了一种用于恢复稀疏卷的数据的技术，其中文件系统结构中的一个或多个块指针被标记为ABSENT，并且根据需要从备用位置获取适当的数据。 对本地存储系统的客户端数据访问请求根据需要启动从后台存储器恢复数据。 还可以使用需求生成器通过遍历稀疏卷并恢复缺席块的数据来将数据恢复为后台进程。 还公开了一种泵模块来调节需求发生器的通路。 一旦所有数据都已恢复，卷将包含本地的所有数据，并且不再是稀疏卷。