公开(公告)号：US09418825B2

公开(公告)日：2016-08-16

申请号：US14762916

申请日：2014-01-27

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Hiroyuki Yasuda ,  Shinya Ito ,  Akira Fujii ,  Yasushi Terui

IPC: H01J49/04 ,  H01J49/16 ,  G01N30/72

CPC classification number: H01J49/0445 ,  G01N30/724 ,  H01J49/165

Abstract: A mass spectrometry is equipped with a liquid specimen supply part which supplies a liquid specimen sandwiched between bubbles, an ion source part ionizes the specimen, and a mass spectrometry part which detects ions separated in accordance with mass. In particular the ion source part is configured so as to include a liquid supply tube for transporting a specimen from the liquid specimen supply part, a degassing/liquid retention part in which bubbles are removed, a spraying part which ionizes the specimen, and a high-voltage power supply part which applies a high voltage to the spraying part. The device is further characterized in that after removing the bubbles, a Taylor cone is formed from the resultant pre-solution, and the specimen is ionized thereafter. Thus, the ionization of an intended specimen is stabilized, and the measurement reproducibility is improved.

Abstract translation: 质谱仪配备有液体试样供给部件，其供给夹在气泡之间的液体试样，离子源部件将样品离子化，以及检测根据质量分离的离子的质谱部分。 特别地，离子源部构成为包括用于从液体试样供给部输送试样的液体供给管，除去气泡的脱气/液体滞留部，使样本电离的喷射部， - 对喷涂部施加高电压的电压电源部。 该装置的特征还在于，在除去气泡之后，由所得预溶液形成泰勒锥体，然后将样品电离。 因此，期望的样品的电离稳定，并且测量再现性提高。

公开(公告)号：US20150198569A1

公开(公告)日：2015-07-16

申请号：US14413603

申请日：2013-07-08

Applicant: Hitachi High-Technologies Corporation

Inventor： Noriko Baba ,  Shinji Yoshioka ,  Hiroyuki Yasuda

IPC: G01N30/72 ,  H01J49/00 ,  G01N30/86

CPC classification number: G01N30/7233 ,  G01N30/72 ,  G01N30/8634 ,  H01J49/0027 ,  H01J49/025

Abstract: Provided is a mass analysis method that prevents quantitative precision from decreasing. This mass analysis method uses an analysis system including a mass analysis device and a subdetector connected to each other, the subdetector displaying intensity and detection time relating to constituents of a sample at a preceding stage of the mass analysis device, the method comprising: (a) after injection of a sample, analyzing the sample with an analyzing apparatus including the subdetector, and after the sample has passed through the subdetector, injecting the sample into the mass analysis device; (b) acquiring data from both the subdetector and the mass analysis device; and (c) determining which of peaks that the subdetector and the mass analysis device have detected is to be analyzed, based on whether overlapping peaks are present and whether the same peak between data from the subdetector and the mass analysis device is present.

Abstract translation: 提供了一种防止定量精度降低的质量分析方法。 该质量分析方法使用包括质量分析装置和彼此连接的子分类器的分析系统，子分割器显示与质量分析装置的前级的样品的成分有关的强度和检测时间，该方法包括：（a ），在分析装置中进行分析，在样品通过分级分析器后，将样品注入质量分析装置; （b）从子分类器和质量分析装置获取数据; 以及（c）基于是否存在重叠峰以及是否存在来自子分类器和质量分析装置的数据之间的相同峰值来确定子分类器和质量分析装置已检测到的哪个峰值将被分析。