公开(公告)号：US07172593B2

公开(公告)日：2007-02-06

申请号：US10634245

申请日：2003-08-05

申请人： Hai H. Trieu ,  Jeff R. Justis ,  Troy D. Drewry ,  Michael C. Sherman ,  Bradley J. Coates ,  Bradley T. Estes

发明人： Hai H. Trieu ,  Jeff R. Justis ,  Troy D. Drewry ,  Michael C. Sherman ,  Bradley J. Coates ,  Bradley T. Estes

IPC分类号： A61B17/56 ,  A61B17/58

CPC分类号： A61B17/8042 ,  A61B17/7059 ,  A61B17/8052 ,  A61B17/8085 ,  A61B17/866 ,  A61B2017/00004 ,  A61F2/0811

摘要： This invention relates to orthopedic implants and to methods of treating bone defects. More specifically, but not exclusively, the present invention is directed to non-metallic implants and to methods for intra-operative assembly and fixation of orthopedic implants to facilitate medical treatment. The non-metallic implant assembly can be secured to underlying tissue by a fastener, such as a bone screw, that is capable of swelling on contact with fluid in the underlying tissue. Alternatively, the non-metallic implant assembly can be assembled intra-operatively using a fastener that is adhesively bonded to a bone plate or the bone plate can be deformed using heat, force, or solvents to inhibit withdrawal of the fastener. In preferred embodiments, both the fastener and the bone plate are formed of biodegradable material.

公开(公告)号：US20110202091A1

公开(公告)日：2011-08-18

申请号：US13097622

申请日：2011-04-29

申请人： Hai H. Trieu ,  Jeff R. Justis ,  Troy D. Drewry ,  Michael C. Sherman ,  Bradley J. Coates ,  Bradley T. Estes

发明人： Hai H. Trieu ,  Jeff R. Justis ,  Troy D. Drewry ,  Michael C. Sherman ,  Bradley J. Coates ,  Bradley T. Estes

IPC分类号： A61B17/88 ,  A61B17/80

CPC分类号： A61B17/8042 ,  A61B17/7059 ,  A61B17/8052 ,  A61B17/8085 ,  A61B17/866 ,  A61B2017/00004 ,  A61F2/0811

摘要： This invention relates to orthopedic implants and to methods of treating bone defects. More specifically, but not exclusively, the present invention is directed to non-metallic implants and to methods for intra-operative assembly and fixation of orthopedic implants to facilitate medical treatment. The non-metallic implant assembly can be secured to underlying tissue by a fastener, such as a bone screw, that is capable of swelling on contact with fluid in the underlying tissue. Alternatively, the non-metallic implant assembly can be assembled intra-operatively using a fastener that is adhesively bonded to a bone plate or the bone plate can be deformed using heat, force, or solvents to inhibit withdrawal of the fastener. In preferred embodiments, both the fastener and the bone plate are formed of biodegradable material.

摘要翻译： 本发明涉及矫形植入物和治疗骨缺损的方法。 更具体地但非唯一地，本发明涉及非金属植入物以及用于手术中组装和固定矫形植入物以方便医疗的方法。 非金属植入物组件可以通过紧固件（例如骨螺钉）固定到下面的组织上，该紧固件能够在与下面的组织中的流体接触时膨胀。 或者，非金属植入物组件可以使用粘合剂粘合到骨板上的紧固件在手术中组装，或者骨板可以使用热，力或溶剂变形以阻止紧固件的拉出。 在优选实施例中，紧固件和骨板都是由可生物降解的材料形成的。

公开(公告)号：US08911480B2

公开(公告)日：2014-12-16

申请号：US13097622

申请日：2011-04-29

申请人： Hai H. Trieu ,  Jeff R. Justis ,  Troy D. Drewry ,  Michael C. Sherman ,  Bradley J. Coates ,  Bradley T. Estes

发明人： Hai H. Trieu ,  Jeff R. Justis ,  Troy D. Drewry ,  Michael C. Sherman ,  Bradley J. Coates ,  Bradley T. Estes

IPC分类号： A61B17/88 ,  A61B17/80 ,  A61B17/86 ,  A61B17/70 ,  A61B17/00 ,  A61F2/08

CPC分类号： A61B17/8042 ,  A61B17/7059 ,  A61B17/8052 ,  A61B17/8085 ,  A61B17/866 ,  A61B2017/00004 ,  A61F2/0811

摘要： This invention relates to orthopedic implants and to methods of treating bone defects. More specifically, but not exclusively, the present invention is directed to non-metallic implants and to methods for intra-operative assembly and fixation of orthopedic implants to facilitate medical treatment. The non-metallic implant assembly can be secured to underlying tissue by a fastener, such as a bone screw, that is capable of swelling on contact with fluid in the underlying tissue. Alternatively, the non-metallic implant assembly can be assembled intra-operatively using a fastener that is adhesively bonded to a bone plate or the bone plate can be deformed using heat, force, or solvents to inhibit withdrawal of the fastener. In preferred embodiments, both the fastener and the bone plate are formed of biodegradable material.

摘要翻译： 本发明涉及矫形植入物和治疗骨缺损的方法。 更具体地但非唯一地，本发明涉及非金属植入物以及用于手术中组装和固定矫形植入物以方便医疗的方法。 非金属植入物组件可以通过紧固件（例如骨螺钉）固定到下面的组织上，该紧固件能够在与下面的组织中的流体接触时膨胀。 或者，非金属植入物组件可以使用粘合剂粘合到骨板上的紧固件在手术中组装，或者骨板可以使用热，力或溶剂变形以阻止紧固件的拉出。 在优选实施例中，紧固件和骨板都是由可生物降解的材料形成的。

公开(公告)号：US07951177B2

公开(公告)日：2011-05-31

申请号：US11703059

申请日：2007-02-06

申请人： Hai H. Trieu ,  Jeff R. Justis ,  Troy D. Drewry ,  Michael C. Sherman ,  Bradley J. Coates ,  Bradley T. Estes

发明人： Hai H. Trieu ,  Jeff R. Justis ,  Troy D. Drewry ,  Michael C. Sherman ,  Bradley J. Coates ,  Bradley T. Estes

IPC分类号： A61B17/80

CPC分类号： A61B17/8042 ,  A61B17/7059 ,  A61B17/8052 ,  A61B17/8085 ,  A61B17/866 ,  A61B2017/00004 ,  A61F2/0811

摘要： This invention relates to orthopedic implants and to methods of treating bone defects. More specifically, but not exclusively, the present invention is directed to non-metallic implants and to methods for intra-operative assembly and fixation of orthopedic implants to facilitate medical treatment. The non-metallic implant assembly can be secured to underlying tissue by a fastener, such as a bone screw, that is capable of swelling on contact with fluid in the underlying tissue. Alternatively, the non-metallic implant assembly can be assembled intra-operatively using a fastener that is adhesively bonded to a bone plate or the bone plate can be deformed using heat, force, or solvents to inhibit withdrawal of the fastener. In preferred embodiments, both the fastener and the bone plate are formed of biodegradable material.

摘要翻译： 本发明涉及矫形植入物和治疗骨缺损的方法。 更具体地但非唯一地，本发明涉及非金属植入物以及用于手术中组装和固定矫形植入物以方便医疗的方法。 非金属植入物组件可以通过紧固件（例如骨螺钉）固定到下面的组织上，该紧固件能够在与下面的组织中的流体接触时膨胀。 或者，非金属植入物组件可以使用粘合剂粘合到骨板上的紧固件在手术中组装，或者骨板可以使用热，力或溶剂变形以阻止紧固件的拉出。 在优选实施例中，紧固件和骨板都是由可生物降解的材料形成的。

公开(公告)号：US06605090B1

公开(公告)日：2003-08-12

申请号：US09696128

申请日：2000-10-25

申请人： Hai H. Trieu ,  Jeff R. Justis ,  Troy D. Drewry ,  Michael C. Sherman ,  Bradley J. Coates ,  Bradley T. Estes

发明人： Hai H. Trieu ,  Jeff R. Justis ,  Troy D. Drewry ,  Michael C. Sherman ,  Bradley J. Coates ,  Bradley T. Estes

IPC分类号： A61B1756

CPC分类号： A61B17/8042 ,  A61B17/7059 ,  A61B17/8052 ,  A61B17/8085 ,  A61B17/866 ,  A61B2017/00004 ,  A61F2/0811

摘要： This invention relates to orthopedic implants and to methods of treating bone defects. More specifically, but not exclusively, the present invention is directed to non-metallic implants and to methods for intra-operative assembly and fixation of orthopedic implants to facilitate medical treatment. The non-metallic implant assembly can be secured to underlying tissue by a fastener, such as a bone screw, that is capable of swelling on contact with fluid in the underlying tissue. Alternatively, the non-metallic implant assembly can be assembled intra-operatively using a fastener that is adhesively bonded to a bone plate or the bone plate can be deformed using heat, force or solvents to inhibit withdrawal of the fastener. In preferred embodiments, both the fastener and the bone plate are formed of biodegradable material.

摘要翻译： 本发明涉及矫形植入物和治疗骨缺损的方法。 更具体地但非唯一地，本发明涉及非金属植入物以及用于手术中组装和固定矫形植入物以方便医疗的方法。 非金属植入物组件可以通过紧固件（例如骨螺钉）固定到下面的组织上，该紧固件能够在与下面的组织中的流体接触时膨胀。 或者，非金属植入物组件可以使用粘合剂粘合到骨板上的紧固件在手术中组装，或者骨板可以使用热，力或溶剂变形以阻止紧固件的拉出。 在优选实施例中，紧固件和骨板都是由可生物降解的材料形成的。

公开(公告)号：US20100268278A1

公开(公告)日：2010-10-21

申请号：US12424083

申请日：2009-04-15

申请人： Kevin T. FOLEY ,  Regis W. Haid ,  Newton H. Metcalf, JR. ,  Bradley J. Coates ,  David Alan Sharp ,  Chris Michael Diaz ,  Virginia Leigh Richardson ,  Jeff R. Justis ,  Hai H. Trieu ,  Jeffrey H. Nycz ,  Greg C. Marik ,  Troy D. Drewry ,  Richard J. Thiele ,  Gary S. Lindemann

发明人： Kevin T. FOLEY ,  Regis W. Haid ,  Newton H. Metcalf, JR. ,  Bradley J. Coates ,  David Alan Sharp ,  Chris Michael Diaz ,  Virginia Leigh Richardson ,  Jeff R. Justis ,  Hai H. Trieu ,  Jeffrey H. Nycz ,  Greg C. Marik ,  Troy D. Drewry ,  Richard J. Thiele ,  Gary S. Lindemann

IPC分类号： A61B17/70 ,  A61B17/84

CPC分类号： A61B17/7059

摘要： Various embodiments of a vertebral tension band assembly and associated connection structure are provided. The tension band assemblies may be attached to vertebral bodies to, for example, connect one vertebrae to another, retain the band in approximately a preferred position by application of tension to the band during insertion and/or limit, impede, inhibit, reduce or interfere with the separation from one vertebra to another and may further block, impede, interfere with, inhibit, reduce or present an obstacle to dislodgement of a spinal implant from between the vertebrae to which it is attached. Flexible band portions of the assemblies may be treated and/or configured to promote bony integration between the band and the associated vertebrae, limit tissue adhesion to the band, and/or to elute a therapeutic substance from the installed band to the surgical site.

摘要翻译： 提供了椎体张力带组件和相关连接结构的各种实施例。 张力带组件可以附接到椎体以例如将一个椎骨连接到另一个椎骨，通过在插入期间施加张力并且/或限制，阻止，抑制，减少或干扰，将带保持在大致优选的位置 具有从一个椎骨到另一个椎骨的分离，并且可以进一步阻止，阻碍，干扰，抑制，减少或呈现脊柱植入物从其所连接的椎骨之间移动的障碍。 组件的柔性带部分可以被处理和/或构造成促进带和相关椎骨之间的骨整合，限制组织对带的粘附，和/或将治疗物质从所安装的带中洗脱到手术部位。

公开(公告)号：US08858599B2

公开(公告)日：2014-10-14

申请号：US10864181

申请日：2004-06-09

申请人： Hai H. Trieu ,  Michael C. Sherman ,  Jeff R. Justis

发明人： Hai H. Trieu ,  Michael C. Sherman ,  Jeff R. Justis

IPC分类号： A61F2/44 ,  A61B17/70

CPC分类号： A61B17/7019 ,  A61B17/7004 ,  A61B17/7031

摘要： Devices, methods and systems for stabilizing at least a portion of the spinal column are provided. Anchors are engageable to vertebra and a stabilization member is engageable between the anchors. The stabilization member includes an elongate tension member and a compression member in a passage of the tension member.

摘要翻译： 提供了用于稳定至少一部分脊柱的装置，方法和系统。 锚固件可接合到椎骨，并且稳定构件可在锚固件之间接合。 稳定构件包括细长的张紧构件和在张紧构件的通道中的压缩构件。

公开(公告)号：US08480718B2

公开(公告)日：2013-07-09

申请号：US11643187

申请日：2006-12-21

申请人： Dimitri Protopsaltis ,  Hai H. Trieu ,  Jeff R. Justis ,  Michael C. Sherman

发明人： Dimitri Protopsaltis ,  Hai H. Trieu ,  Jeff R. Justis ,  Michael C. Sherman

IPC分类号： A61B17/84 ,  A61F2/44 ,  A61B17/80 ,  A61B17/70

CPC分类号： A61B17/866 ,  A61B17/7013 ,  A61B17/7032 ,  A61B17/7049 ,  A61B17/80 ,  A61B17/8605 ,  A61B17/8625 ,  A61B17/8836 ,  A61F2/441 ,  A61F2/4425 ,  A61F2/4455 ,  A61F2/4465 ,  A61F2/447 ,  A61F2002/2835 ,  A61F2002/30062 ,  A61F2002/302 ,  A61F2002/30225 ,  A61F2002/30545 ,  A61F2002/30556 ,  A61F2002/30583 ,  A61F2002/30677 ,  A61F2002/30884 ,  A61F2002/3092 ,  A61F2002/444 ,  A61F2002/4495 ,  A61F2002/465 ,  A61F2210/0004 ,  A61F2210/0085 ,  A61F2230/0065 ,  A61F2230/0069 ,  A61F2250/0009 ,  A61F2250/001

摘要： Orthopedic implants include a device that is non-rigid, i.e., flexible and/or malleable, in a first form for insertion into a desired in vivo site, and then transformable into a rigid, or hardened, form for providing a load-bearing function or providing other structural and/or mechanical function after implant. The device includes a biocompatible sheath and a curable material sealed within the sheath. The curable material is provided in a first form that provides flexibility to the device and is structured to rigidize in a second form after application of a quantity of an initiating energy to the material. Related methods and kits are also provided.

摘要翻译： 矫形植入物包括非刚性的，即柔性的和/或有延展性的装置，其以第一形式插入到期望的体内部位，然后可变形成刚性或硬化的形式，以提供承载功能 或在植入后提供其他结构和/或机械功能。 该装置包括生物相容护套和密封在护套内的可固化材料。 可固化材料以提供该装置的柔性的第一形式提供，并且被构造成在将一定量的起始能量施加到材料之后以第二形式刚性化。 还提供了相关方法和试剂盒。

公开(公告)号：US20080154373A1

公开(公告)日：2008-06-26

申请号：US11643187

申请日：2006-12-21

申请人： Dimitri Protopsaltis ,  Hai H. Trieu ,  Jeff R. Justis ,  Michael C. Sherman

发明人： Dimitri Protopsaltis ,  Hai H. Trieu ,  Jeff R. Justis ,  Michael C. Sherman

IPC分类号： A61F2/44

CPC分类号： A61B17/866 ,  A61B17/7013 ,  A61B17/7032 ,  A61B17/7049 ,  A61B17/80 ,  A61B17/8605 ,  A61B17/8625 ,  A61B17/8836 ,  A61F2/441 ,  A61F2/4425 ,  A61F2/4455 ,  A61F2/4465 ,  A61F2/447 ,  A61F2002/2835 ,  A61F2002/30062 ,  A61F2002/302 ,  A61F2002/30225 ,  A61F2002/30545 ,  A61F2002/30556 ,  A61F2002/30583 ,  A61F2002/30677 ,  A61F2002/30884 ,  A61F2002/3092 ,  A61F2002/444 ,  A61F2002/4495 ,  A61F2002/465 ,  A61F2210/0004 ,  A61F2210/0085 ,  A61F2230/0065 ,  A61F2230/0069 ,  A61F2250/0009 ,  A61F2250/001

摘要： Orthopedic implants include a device that is non-rigid, i.e., flexible and/or malleable, in a first form for insertion into a desired in vivo site, and then transformable into a rigid, or hardened, form for providing a load-bearing function or providing other structural and/or mechanical function after implant. The device includes a biocompatible sheath and a curable material sealed within the sheath. The curable material is provided in a first form that provides flexibility to the device and is structured to rigidize in a second form after application of a quantity of an initiating energy to the material. Related methods and kits are also provided.

摘要翻译： 矫形植入物包括非刚性的，即柔性的和/或有延展性的装置，其以第一形式插入到期望的体内部位，然后可变形成刚性或硬化的形式，以提供承载功能 或在植入后提供其他结构和/或机械功能。 该装置包括生物相容护套和密封在护套内的可固化材料。 可固化材料以提供该装置的柔性的第一形式提供，并且被构造成在将一定量的起始能量施加到材料之后以第二形式刚性化。 还提供了相关方法和试剂盒。

公开(公告)号：US20080154266A1

公开(公告)日：2008-06-26

申请号：US11643175

申请日：2006-12-21

申请人： Dimitri Protopsaltis ,  Jeff R. Justis ,  Hai H. Trieu ,  Michael C. Sherman

发明人： Dimitri Protopsaltis ,  Jeff R. Justis ,  Hai H. Trieu ,  Michael C. Sherman

IPC分类号： A61B17/00 ,  A61B17/56

CPC分类号： A61B17/7032 ,  A61B17/7013 ,  A61B17/7035 ,  A61B17/7059 ,  A61B2017/00557 ,  A61B2017/00831 ,  A61B2017/00946 ,  A61F2/44 ,  A61F2/441 ,  A61F2/4425 ,  A61F2/4455 ,  A61F2002/30062 ,  A61F2002/3009 ,  A61F2002/302 ,  A61F2002/30556 ,  A61F2002/30583 ,  A61F2002/30677 ,  A61F2002/30884 ,  A61F2002/3092 ,  A61F2002/444 ,  A61F2002/4495 ,  A61F2002/465 ,  A61F2002/4692 ,  A61F2210/0004 ,  A61F2210/0085 ,  A61F2230/0065 ,  A61F2250/0009 ,  A61F2250/0091

摘要： Orthopedic implant devices are positioned at a desired in vivo site by positioning a device that is non-rigid, i.e., flexible and/or malleable, in a first form, and then transformable after insertion to the in vivo site into a rigid, or hardened, form for providing a load-bearing function or providing other structural and/or mechanical function after implant. The device includes a biocompatible sheath and a curable material sealed within the sheath. The curable material is provided in a first form that provides flexibility to the device and is structured to rigidize in a second form after application of a quantity of an initiating energy to the material.

摘要翻译： 骨科植入装置通过将第一形式的非刚性的，即柔性的和/或可延展的装置定位在期望的体内部位，然后在插入到体内部位之后可变形成刚性或硬化的 ，用于提供承载功能或在植入后提供其他结构和/或机械功能的形式。 该装置包括生物相容护套和密封在护套内的可固化材料。 可固化材料以提供该装置的柔性的第一形式提供，并且被构造成在将一定量的起始能量施加到材料之后以第二形式刚性化。