利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

31 条记录 (耗时 0.045 秒)

    Direct solid sample analytical technology for determining a content and a uniformity thereof in a lyophilized kit of a sulfur-containing chelator with a stable complex capacity for radiotechnetium (Tc-99M) and radiorhenium (Re-186, Re-188)
    4.
    发明授权
    Direct solid sample analytical technology for determining a content and a uniformity thereof in a lyophilized kit of a sulfur-containing chelator with a stable complex capacity for radiotechnetium (Tc-99M) and radiorhenium (Re-186, Re-188) 有权
    用于确定具有稳定的放射性核磁共振能力（Tc-99M）和镭（Re-186，Re-188）的含硫螯合剂的冻干试剂盒中的含量和均匀性的直接固体样品分析技术，

    公开(公告)号：US08831891B2

    公开(公告)日：2014-09-09

    申请号：US13273346

    申请日：2011-10-14

    申请人： Kung-Tien Liu ,  Ming-Yu Chao ,  Yi-Chih Hsia ,  Shih-Woei Yeh ,  Mei-Hsiu Liao ,  Lee-Chung Men ,  Lie-Hang Shen

    发明人： Kung-Tien Liu ,  Ming-Yu Chao ,  Yi-Chih Hsia ,  Shih-Woei Yeh ,  Mei-Hsiu Liao ,  Lee-Chung Men ,  Lie-Hang Shen

    IPC分类号： A61K51/04

    CPC分类号： A61K51/0478

    摘要： The present invention is related to a direct solid sample analytical technology for determining a content and a uniformity thereof in a lyophilized kit of a sulfur-containing chelator with a stable complex capacity for radiotechnetium (Tc-99m) and radiorhenium (Re-186, Re-188). An economical, stable and easily accessible coal standard is used herein as a contrast substance to construct a sulfur calibration curve, followed by obtaining the sulfur content and the uniformity thereof in the solid lyophilized sample by interpolating the foregoing result into the sulfur calibration curve. Then, the weight content percent is converted to get the content and the uniformity of the chelator in the lyophilized kit. The quality control of active pharmaceutical ingredients (API) in the lyophilized kit during key production processes and clinical applications is thus assured.

    摘要翻译： 本发明涉及一种直接固体样品分析技术，用于确定具有稳定的放射性核磁共振能力（Tc-99m）和镭（Re-186，Re）的含硫螯合剂的冻干试剂盒中的含量和均匀性 -188）。 本文中使用经济，稳定且易于获得的煤标准作为对比物质来构建硫校准曲线，随后通过将上述结果内插到硫校准曲线中来获得固体冻干样品中的硫含量及其均匀性。 然后，将重量含量百分比转化为获得冻干试剂盒中螯合剂的含量和均匀性。 因此，确保了关键生产过程和临床应用中冻干试剂盒中活性药物成分（API）的质量控制。

    DIRECT SOLID SAMPLE ANALYTICAL TECHNOLOGY FOR DETERMINING A CONTENT AND A UNIFORMITY THEREOF IN A LYOPHILIZED KIT OF A SULFUR-CONTAINING CHELATOR WITH A STABLE COMPLEX CAPACITY FOR RADIOTECHNETIUM (TC-99M) AND RADIORHENIUM (RE-186, RE-188)
    5.
    发明申请
    DIRECT SOLID SAMPLE ANALYTICAL TECHNOLOGY FOR DETERMINING A CONTENT AND A UNIFORMITY THEREOF IN A LYOPHILIZED KIT OF A SULFUR-CONTAINING CHELATOR WITH A STABLE COMPLEX CAPACITY FOR RADIOTECHNETIUM (TC-99M) AND RADIORHENIUM (RE-186, RE-188) 有权
    用于确定具有稳定的放射性复合容量（TC-99M）和放射性阳离子（RE-186，RE-188）的具有稳定复合容量的含硫化合物的LYOPHILIZED试剂盒中的内容物和其均匀性的直接固体样品分析技术

    公开(公告)号：US20120101741A1

    公开(公告)日：2012-04-26

    申请号：US13273346

    申请日：2011-10-14

    申请人： KUNG-TIEN LIU ,  Ming-Yu Chao ,  Yi-Chih Hsia ,  Shih-Woei Yeh ,  Mei-Hsiu Liao ,  Lee-Chung Men ,  Lie-Hang Shen

    发明人： KUNG-TIEN LIU ,  Ming-Yu Chao ,  Yi-Chih Hsia ,  Shih-Woei Yeh ,  Mei-Hsiu Liao ,  Lee-Chung Men ,  Lie-Hang Shen

    IPC分类号： G06F19/00

    CPC分类号： A61K51/0478

    摘要： The present invention is related to a direct solid sample analytical technology for determining a content and a uniformity thereof in a lyophilized kit of a sulfur-containing chelator with a stable complex capacity for radiotechnetium (Tc-99m) and radiorhenium (Re-186, Re-188). An economical, stable and easily accessible coal standard is used herein as a contrast substance to construct a sulfur calibration curve, followed by obtaining the sulfur content and the uniformity thereof in the solid lyophilized sample by interpolating the foregoing result into the sulfur calibration curve. Then, the weight content percent is converted to get the content and the uniformity of the chelator in the lyophilized kit. The quality control of active pharmaceutical ingredients (API) in the lyophilized kit during key production processes and clinical applications is thus assured.

    摘要翻译： 本发明涉及一种直接固体样品分析技术，用于确定具有稳定的放射性核磁共振能力（Tc-99m）和镭（Re-186，Re）的含硫螯合剂的冻干试剂盒中的含量和均匀性 -188）。 本文中使用经济，稳定且易于获得的煤标准作为对比物质来构建硫校准曲线，随后通过将上述结果内插到硫校准曲线中来获得固体冻干样品中的硫含量及其均匀性。 然后，将重量含量百分比转化为获得冻干试剂盒中螯合剂的含量和均匀性。 因此，确保了关键生产过程和临床应用中冻干试剂盒中活性药物成分（API）的质量控制。

    AUTOMATED SYNTHESIS SYSTEM FOR IODINE-123-IBZM NUCLEAR MEDICINE
    6.
    发明申请
    AUTOMATED SYNTHESIS SYSTEM FOR IODINE-123-IBZM NUCLEAR MEDICINE 审中-公开
    自动合成系统，用于碘-123-IBZM核医学

    公开(公告)号：US20140072482A1

    公开(公告)日：2014-03-13

    申请号：US13611710

    申请日：2012-09-12

    申请人： Chia-Jung Chang ,  Wei-Kang Chou ,  An-Shoei Yang ,  Mei-Hsiu Liao ,  Lie-Hang Shen

    发明人： Chia-Jung Chang ,  Wei-Kang Chou ,  An-Shoei Yang ,  Mei-Hsiu Liao ,  Lie-Hang Shen

    IPC分类号： B01J19/24

    CPC分类号： B01J19/004 ,  B01J19/0093 ,  B01J2219/00799 ,  B01J2219/00813 ,  B01J2219/00817 ,  B01J2219/00831 ,  B01J2219/00867 ,  B01J2219/00889 ,  B01J2219/00894 ,  B01J2219/00918 ,  B01J2219/00927

    摘要： An automated synthesis system for iodine-123-IBZM nuclear medicine includes a control/display means, a reactant supply means connecting to the control/display means; an adsorption means connecting to the control/display means and to the reactant supply means, an oxidation means connecting the control/display means, the reactant supply means and the adsorption means, a product collection means connecting to the control/display means, the reactant supply means, the adsorption means and the oxidation means; a waste liquid collection means connecting to the control/display means, the adsorption means and the product collection means, and a gas filtration means connecting the control/display means, the oxidation means and the product collection means. This system can automate the processing steps needed for marking, such as oxidation, reduction, neutralization, adsorption, washing and elution etc, and reduce hand operating time, radiation exposure dose, and mistakes and deviations, while stabilizing the product quality, increasing the product yield, and improving the purity.

    摘要翻译： 碘-123-IBZM核药物的自动合成系统包括控制/显示装置，连接到控制/显示装置的反应物供应装置; 连接到控制/显示装置和反应物供应装置的吸附装置，连接控制/显示装置，反应物供应装置和吸附装置的氧化装置，连接到控制/显示装置的产品收集装置，反应物 供给装置，吸附装置和氧化装置; 连接到控制/显示装置，吸附装置和产品收集装置的废液收集装置，以及连接控制/显示装置，氧化装置和产品收集装置的气体过滤装置。 该系统可以自动化氧化，还原，中和，吸附，洗涤和洗脱等标记所需的加工步骤，减少手工操作时间，辐射暴露剂量，错误和偏差，同时稳定产品质量，增加产品 产率，提高纯度。

    Radiation Method for Fabrication of Nano-sized Compound Antibacterial Fabric Textile
    9.
    发明申请
    Radiation Method for Fabrication of Nano-sized Compound Antibacterial Fabric Textile 审中-公开
    纳米复合抗菌织物的制备辐射方法

    公开(公告)号：US20090092645A1

    公开(公告)日：2009-04-09

    申请号：US11867701

    申请日：2007-10-05

    申请人： Te-Hsing Wu ,  Bin Lin ,  Nini-Chen Tsai ,  Chia-Chieh Chen ,  Lie-Hang Shen ,  Wuu-Jyh Lin

    发明人： Te-Hsing Wu ,  Bin Lin ,  Nini-Chen Tsai ,  Chia-Chieh Chen ,  Lie-Hang Shen ,  Wuu-Jyh Lin

    IPC分类号： A61K9/70 ,  A61P31/04

    CPC分类号： A61L15/14 ,  A61K9/10 ,  A61K47/02 ,  A61L15/46 ,  A61L2300/104 ,  A61L2300/404 ,  A61L2300/624 ,  D06M10/008 ,  D06M10/06 ,  D06M11/65 ,  D06M11/79 ,  D06M11/83 ,  D06M16/00 ,  D06M23/08 ,  D06M2101/32 ,  D06M2101/34

    摘要： The invention discloses an innovative process to produce highly antibacterial nano-composite fabric textile containing silver metal compound. The process mainly uses high-energy D-ray radiation to modify silver type of bactericides and graft or crosslink them onto Nylon or PET fiber surface to produce excellent antibacterial textile products. The mechanism uses silver nano-compound as performance additive and through Co-60 irradiation technique reduces and firmly fastens silver particles onto Nylon or PET (Polyethylene Terephthalate) fiber material. Because the inorganic silver type bactericides actively interact with enzymes in bacteria or destroy cell walls to achieve good bactericidal effect, the radiation process does not need initiators or other additives. So the process is simple and effective. The test results prove excellent bactericidal power and potential value in household or medical textile products.

    摘要翻译： 本发明公开了一种生产含有银金属化合物的高抗菌纳米复合织物织物的创新方法。 该方法主要采用高能D射线辐射法改性银类杀菌剂，并将其接枝或交联到尼龙或PET纤维表面，生产出优良的抗菌纺织品。 该机理采用银纳米复合材料作为性能添加剂，通过Co-60辐照技术可将银粒子还原并牢固地固定在尼龙或PET（聚对苯二甲酸乙二醇酯）纤维材料上。 由于无机银型杀菌剂与细菌中的酶积极相互作用或破坏细胞壁以达到良好的杀菌效果，所以辐射过程不需要引发剂或其他添加剂。 所以这个过程很简单有效。 测试结果证明了家用或医用纺织品的优良杀菌力和潜在价值。