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24 条记录 (耗时 0.019 秒)

    Acid addition products of N-glycidyl compounds
    5.
    发明授权
    Acid addition products of N-glycidyl compounds 失效
    N-缩水甘油基化合物的酸加成产物

    公开(公告)号：US4659824A

    公开(公告)日：1987-04-21

    申请号：US643611

    申请日：1984-08-23

    申请人： Hinrich Moller

    发明人： Hinrich Moller

    IPC分类号： A61K31/41 ,  A61K31/53 ,  A61P35/00 ,  C07D249/12 ,  C07D405/06 ,  C07D405/14 ,  C07D403/06 ,  C07D233/02 ,  C07D253/06

    CPC分类号： C07D405/14 ,  C07D405/06

    摘要： A process for the selective production of defined, partial reaction products of polyfunctional N-glycidyl compounds with hydrohalic acids, pseudohydrohalic acids or acids of phosphorus; mono- or di-ring opening products are obtainable as required. The process is carried out at a pH of from about 2 to 10 which is kept constant within a band of at most 2 units on the pH-scale. N,N'-diglycidyl-N"-(halohydroxypropyl)-urazoles and N-glycidyl-N,N"-bis(halohydroxypropyl) urazoles having pharmaceutical utility are produced in good yield.

    摘要翻译： 选择性地制备多官能N-缩水甘油基化合物与氢卤酸，假卤代酸或磷酸的定义的部分反应产物的方法; 可根据需要获得单环或二环开口产品。 该过程在约2至10的pH下进行，其在pH范围内保持恒定在至多2个单位的带内。 具有药用效用的N，N'-二缩水甘油基-N“ - （卤代羟丙基） - 脲和N-缩水甘油基-N，N” - 双（卤代羟丙基）吖唑以良好的产率生产。

    Amphoteric and zwitter-ionic phosphate surfactants
    7.
    发明授权
    Amphoteric and zwitter-ionic phosphate surfactants 失效
    两性和两性离子磷酸盐表面活性剂

    公开(公告)号：US4824603A

    公开(公告)日：1989-04-25

    申请号：US115003

    申请日：1987-10-28

    申请人： Hinrich Moller ,  Ulrich Zeidler

    发明人： Hinrich Moller ,  Ulrich Zeidler

    IPC分类号： A61K8/55 ,  A61Q5/02 ,  A61Q19/10 ,  B01F17/14 ,  B01F17/18 ,  C07F9/09 ,  C07F9/40 ,  C11D1/88 ,  C11D1/62 ,  C11D1/94

    CPC分类号： C11D1/886 ,  A61K8/55 ,  A61Q19/10 ,  A61Q5/02 ,  C07F9/091

    摘要： Amphoteric and zwitter-ionic phosphate surfactants corresponding to the following formula ##STR1## (a) in which R.sup.1 is a C.sub.6 -C.sub.22 alkyl group, a group R.sup.4 (OC.sub.n H.sub.2n).sub.x --, where n=2 to 4, x=1 to 6, and R.sup.4 is a C.sub.6 -C.sub.22 alkyl group, or a group R.sup.5 --CONH(CH.sub.2).sub.m, where R.sup.5 is a C.sub.5 -C.sub.21 group and m=2 to 4; R.sup.2 is hydrogen; and R.sup.3 is a C.sub.1 -C.sub.4 alkyl group or a group --(C.sub.n H.sub.2n O).sub.x --H or --(C.sub.n H.sub.2n O).sub.x --PO.sub.3 H.sub.2, where n=2 to 4 and x=1 to 6, or(b) in which R.sup.1 is a C.sub.1 -C.sub.4 alkyl group or a C.sub.2 -C.sub.4 2-hydroxyalkyl group; R.sup.2 is a C.sub.6 -C.sub.22 alkyl group; and R.sup.3 is as defined above.to mixtures thereof with correspondingly substituted phosphate surfactants corresponding to formula (I), in which the --PO.sub.3 H.sub.2 group or groups are replaced by hydrogen; and to neutral and basic salts of the foregoing. The invention also relates to processes for the manufacture of the above surfactants, and to their use as skin-compatible washing-active components in body shampoos and hair shampoos.

    摘要翻译： 对应于下列式（Ⅰ）（a）的两性和两性离子型磷酸酯表面活性剂，其中R 1为C 6 -C 22烷基，R 4（OC n H 2n）x - ，其中n = 2至4，x = 1〜6，R4为C6〜C22烷基，R5〜CONH（CH2）m基，R5为C5-C21基，m = 2〜4; R2是氢; R3为C1-C4烷基或 - （CnH2nO）xH或 - （CnH2nO）x-PO3H2，其中n = 2〜4，x = 1〜6，或（b）其中R1为C1- C4烷基或C2-C42-羟烷基; R2是C6-C22烷基; 并且R 3如上所定义。 与对应于式（I）的相应取代的磷酸盐表面活性剂的混合物，其中-PO 3 H 2基团被氢取代; 以及前述的中性和碱性盐。 本发明还涉及制造上述表面活性剂的方法，以及它们在人体洗发剂和洗发剂中作为皮肤相容的洗涤活性成分的用途。

    Method of moisturizing the skin with carbamide acid esters
    8.
    发明授权
    Method of moisturizing the skin with carbamide acid esters 失效
    用氨基酸酯保湿皮肤的方法

    公开(公告)号：US4382765A

    公开(公告)日：1983-05-10

    申请号：US206974

    申请日：1980-11-14

    申请人： Hinrich Moller ,  Rainer Osberghaus ,  Manfred Budnowski

    发明人： Hinrich Moller ,  Rainer Osberghaus ,  Manfred Budnowski

    IPC分类号： A61K8/72 ,  A61K20060101 ,  A61K8/40 ,  A61K8/44 ,  A61K8/49 ,  A61K8/92 ,  A61K8/97 ,  A61K47/00 ,  A61Q17/00 ,  A61Q19/00 ,  C07C20060101 ,  C07C271/06 ,  C07D263/20 ,  C11D3/32 ,  C11D9/30 ,  A61K7/42 ,  A61K7/15

    CPC分类号： A61K8/44 ,  A61K8/0212 ,  A61K8/49 ,  A61Q17/00 ,  A61Q19/00 ,  A61Q17/04 ,  A61Q19/002 ,  A61Q19/10 ,  Y10S514/938

    摘要： Skin-care, skin-protection, and skin-cleaning agent compositions containing as a skin-moisturizing agent at least one substituted carbamide acid ester, said substituted carbamide acid ester having the formula ##STR1## wherein R.sub.1 is a member selected from the group consisting of an alkyl radical, having 1 to 4 carbon atoms, alkylol having 2 to 4 carbon atoms and alkyldiol having 3 to 4 carbon atoms, R.sub.2 is a hydroxyalkyl having 2 to 6 carbon atoms and having 1 to 5 hydroxyl groups, or R.sub.2, together with R.sub.1, is an alkylene having 2 to 4 carbon atoms in its chain, which is optionally substituted by lower alkyl and/or lower hydroxyalkyl radicals, and R.sub.3 is a member selected from the group consisting of hydrogen, alkyl having 1 to 4 carbon atoms and hydroxyalkyl having 2 to 4 carbon atoms, or an N-alkenyl polymer of the above cyclic carbamide acid ester, where R.sub.1 and R.sub.2 are alkylene and R.sub.3 is alkenyl having 2 to 4 carbon atoms, as well as a process for protecting the skin utilizing this composition.

    摘要翻译： 皮肤保护剂，皮肤保护剂和皮肤清洁剂组合物，其含有至少一种取代的脲酰胺酸酯作为皮肤保湿剂，所述具有式“IMAGE”的取代的脲酰胺酸酯，其中R1是选自 的具有1至4个碳原子的烷基，具有2至4个碳原子的烷基醇和具有3至4个碳原子的烷基二醇，R 2是具有2至6个碳原子并具有1至5个羟基的羟烷基，或者R 2一起 其中R 1是其链中具有2至4个碳原子的亚烷基，其任选被低级烷基和/或低级羟烷基取代，并且R 3是选自氢，具有1至4个碳原子的烷基 和具有2至4个碳原子的羟基烷基，或上述环状氨基甲酸酯的N-烯基聚合物，其中R 1和R 2是亚烷基，R 3是具有2至4个碳原子的烯基，以及利用 这个compos 游戏