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公开(公告)号：US4614723A
公开(公告)日：1986-09-30
申请号：US613127
申请日：1984-05-23
申请人： Dieter Schmidt , Hans Steffen
发明人： Dieter Schmidt , Hans Steffen
IPC分类号： C07D487/22 , G01N33/533
CPC分类号： C07D487/22 , G01N33/533 , Y10S436/80
摘要： There are described novel porphyrin derivatives of the general formula ##STR1## wherein either R.sup.1 signifies the group ##STR2## and R.sup.2 signifies the group ##STR3## or R.sup.1 signifies the group ##STR4## and R.sup.2 signifies the group ##STR5## whereby X.sup.- signifies a halogen ion, an arylsulphonate ion, an alkylsulphonate ion or an alkyl sulphate ion, A signifies (C.sub.1-8)-alkylene and R.sup.3 signifies (C.sub.1-4)-alkyl,and sulphonic acid salts of compounds of formula I in which R.sup.1 signifies the group ##STR6## as well as a process for their manufacture and intermediates used in this process.Because of their water-solubility the novel porphyrin derivatives are suitable as label molecules for highly sensitive fluorescence immuno-assays, especially for time-resolving fluorescence immuno-assays. The coupling of the novel porphyrin derivatives to immunologically-active materials is carried out in the customary manner, for example with a water-soluble carbodiimide derivative.
摘要翻译： 描述了通式为“IMAGE”I的新型卟啉衍生物，其中R1表示基团“IMAGE”，R2表示组
+ TR ，或R1表示组 ，R2表示组< 其中X表示卤素离子，芳基磺酸根离子，烷基磺酸根离子或烷基硫酸根离子，A表示（C 1-8） - 亚烷基，R 3表示（C 1-4） - 烷基， 其中R1表示组 的式I，以及其制造方法和在该方法中使用的中间体。 由于它们的水溶性，新的卟啉衍生物适用于高灵敏度荧光免疫分析的标签分子，特别是用于时间分辨荧光免疫测定。 新型卟啉衍生物与免疫活性物质的偶合以常规方式进行，例如用水溶性碳二亚胺衍生物进行。 -
公开(公告)号：US4158707A
公开(公告)日：1979-06-19
申请号：US813913
申请日：1977-07-08
申请人： Hans Steffen , Dieter Schmidt
发明人： Hans Steffen , Dieter Schmidt
CPC分类号： A61K9/1075
摘要： Aqueous vehicles for insoluble or sparingly soluble medicaments suitable for parenteral administration are disclosed. The subject vehicles contain, in addition to pharmaceutical adjunct materials to render them isotonic, preserve them and the like, a micelle forming agent comprising cholic acid or a derivative thereof in combination with a lipoid.
摘要翻译： 公开了适用于肠胃外给药的不溶性或微溶药物的水性载体。 本发明的载体除了含有等渗剂的药用辅料外，还含有包含胆酸或其衍生物与脂质组合的胶束形成剂。
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公开(公告)号：US09074946B2
公开(公告)日：2015-07-07
申请号：US13314417
申请日：2011-12-08
摘要： A thermometer with protective tube inner part for insertion into a protective tube, especially a protective tube of a thermometer, wherein the protective tube inner part serves for arranging conductor elements, and wherein the protective tube inner part is matched to the shape of the inside of the protective tube in the region of a closed, protective tube end, and wherein the protective tube inner part serves to arrange the conductor elements on the side of the protective tube inner part facing the protective tube in the installed state.
摘要翻译： 一种具有保护管内部的温度计，用于插入保护管中，特别是温度计的保护管，其中保护管内部用于布置导体元件，并且其中保护管内部与内部的形状相匹配 所述保护管在封闭的保护管端部的区域中，并且其中所述保护管内部用于在所述安装状态下将所述导体元件布置在面向所述保护管的所述保护管内侧的一侧。
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4.发明授权Disposable container having sensor mounts sealed to the container and sensors in the sensor mounts for measuring at least one parameter of media in the container 有权具有密封到容器的传感器安装件和传感器安装件中的传感器的一次性容器，用于测量容器中的介质的至少一个参数公开(公告)号：US08123397B2
公开(公告)日：2012-02-28
申请号：US11643548
申请日：2006-12-21
IPC分类号： B01F15/04
CPC分类号： B01F7/162 , B01F15/00207 , B01F15/0022 , B01F15/00831 , B01F15/0085 , B01L3/505
摘要： A disposable container is provided for mixing media. The container has at least one closable opening for introducing and/or removing media and has sensor mounts at spaced apart locations on the wall of the container. Each sensor mount has a front surface facing into the container and a rear surface sealed against the wall of the container. Sensors are embedded in the respective sensor mounts at positions adjacent the front surfaces. The sensors measure at least one specified parameter of the media at spaced apart locations in the container. The seals between the rear surfaces of the sensor mounts and the wall of the container ensure sterility for the media in the container.
摘要翻译： 提供一次性容器用于混合介质。 容器具有用于引入和/或移除介质的至少一个可关闭的开口，并且在容器的壁上的间隔开的位置处具有传感器安装件。 每个传感器支架具有面向容器的前表面和密封在容器的壁上的后表面。 传感器嵌入相邻的传感器安装座位于与前表面相邻的位置。 传感器在容器中的间隔开的位置测量介质的至少一个指定参数。 传感器支架后表面和容器壁之间的密封确保了容器中介质的无菌性。
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公开(公告)号：US08123395B2
公开(公告)日：2012-02-28
申请号：US12319727
申请日：2009-01-12
IPC分类号： B01F15/04
CPC分类号： B01F7/162 , B01F15/00207 , B01F15/0022 , B01F15/00831 , B01F15/0085 , B01L3/505
摘要： A method is provided for mixing media in a container. The method includes introducing a first media into the container and then introducing a second media into the container while mixing the media to form a mixture. The method continues by measuring the values of two parameters of the mixture at spaced apart locations in the container. The introduction of the second media into the container may be interrupted based on a comparison of the measured values to a preselected intended value.
摘要翻译： 提供了用于将容器中的介质混合的方法。 该方法包括将第一介质引入容器中，然后将第二介质引入容器中同时混合介质以形成混合物。 该方法通过在容器中的间隔开的位置处测量混合物的两个参数的值来继续。 可以基于将测量值与预选的预期值的比较来中断将第二介质引入容器中。
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公开(公告)号：US20110148597A1
公开(公告)日：2011-06-23
申请号：US13059362
申请日：2009-11-05
申请人： Oscar-Werner Reif , Reinhard Baurnfalk , Dieter Schmidt , Christian Oldendorf , Swen Weitemeier
发明人： Oscar-Werner Reif , Reinhard Baurnfalk , Dieter Schmidt , Christian Oldendorf , Swen Weitemeier
IPC分类号： G06K7/01
CPC分类号： B01F13/1055 , B01F15/0445
摘要： A dosing system and a method for dosing a medium, having a dosing control unit (4), at least one exchangeable container (2) containing a medium to be dosed, and a dosing valve (3, 3′) that can be connected to the container (2), wherein at least one part of the dosing valve (3, 3′) that comes into contact with the medium is designed as an exchangeable system component (7, 10) and has a machine-readable code for identification purposes, wherein at least one container (2), as an exchangeable system component (2), has a machine-readable code for identification purposes, wherein the exchangeable parts (2, 7, 10, 19) that come into contact with the medium are designed as disposable parts, and wherein the dosing control unit (4) is connected with a communication unit (5) to read the codes, and wherein the communication unit (5) has a unique read connection (22) to each exchangeable system component (2, 7, 10, 19) or its code.
摘要翻译： 一种定量给料系统和一种用于计量介质的方法，所述计量系统和方法具有计量控制单元（4），包含待计量介质的至少一个可替换容器（2）和可连接到 所述容器（2），其中与所述介质接触的所述计量阀（3,3'）的至少一部分被设计为可更换系统部件（7,10），并且具有用于识别目的的机器可读代码 ，其中作为可交换系统组件（2）的至少一个容器（2）具有用于识别目的的机器可读代码，其中与介质接触的可更换部件（2,7,10,19）是 设计为一次性部件，并且其中所述计量控制单元（4）与通信单元（5）连接以读取代码，并且其中所述通信单元（5）具有到每个可更换系统组件的唯一读取连接（22） 2，7，10，19）或其代码。
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公开(公告)号：US20090147617A1
公开(公告)日：2009-06-11
申请号：US12319727
申请日：2009-01-12
IPC分类号： G05D11/02
CPC分类号： B01F7/162 , B01F15/00207 , B01F15/0022 , B01F15/00831 , B01F15/0085 , B01L3/505
摘要： Container and method for the mixing of media, in particular as a disposable container, which has at least one closable opening for the introduction and/or removal of the media and has a first sensor for measurement of at least one parameter of the mixture, in which at least one second sensor for measurement of the same parameter is arranged at a distance from the first sensor.
摘要翻译： 用于混合介质，特别是作为一次性容器的容器和方法，其具有用于引入和/或移除介质的至少一个可闭合的开口，并且具有用于测量混合物的至少一个参数的第一传感器， 其中用于测量相同参数的至少一个第二传感器布置在离第一传感器一定距离处。
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公开(公告)号：US20080256910A1
公开(公告)日：2008-10-23
申请号：US12054978
申请日：2008-03-25
申请人： Detlef Nuppenau , Gabriele Oelerich , Dieter Schmidt , Eugen Kruger , Regine Wrage , Harald Romer
发明人： Detlef Nuppenau , Gabriele Oelerich , Dieter Schmidt , Eugen Kruger , Regine Wrage , Harald Romer
IPC分类号： B01D50/00
CPC分类号： A47L9/20 , A47L9/106 , A47L9/1666 , B04C9/00 , B04C2009/002 , B04C2009/004 , Y10S55/03
摘要： An apparatus for the elimination of dusts from gases, with a filter arrangement, which is flown through by a loaded volume flow, and a cyclone which is arranged upstream to the filter arrangement, wherein a collector funnel below the filter arrangement forms the cover of the cyclone, wherein a branch stub forming the dust outlet opening of the collector funnel forms the dip pipe of the cyclone and an outlet opening of the cyclone is connected to a dust collector tank arranged under it.
摘要翻译： 一种用于消除来自气体的灰尘的装置，具有通过负载的体积流量流过的过滤器装置，以及设置在过滤器装置上游的旋风分离器，其中过滤装置下方的收集漏斗形成 旋风分离器，其中形成收集器漏斗的灰尘出口的分支短管形成旋风分离器的浸入管，并且旋风分离器的出口连接到布置在其下方的集尘罐。
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9.发明申请Apparatus for removing samples from systems having flexible walls and for introducing fluids into the same 有权用于从具有柔性壁的系统中去除样品并将流体引入其中的装置公开(公告)号：US20070227270A1
公开(公告)日：2007-10-04
申请号：US11713978
申请日：2007-03-05
IPC分类号： G01N1/14
CPC分类号： G01N35/1079 , A61J1/12 , A61J1/20 , C12M33/00 , C12M37/04 , G01N2001/1056
摘要： The invention discloses an apparatus for removing samples or introducing fluids from/into system(s) having flexible walls. A sampler/fluid dispenser (3) is fixed on the outside with a connecting area (4) of its base (5) on a sample removal region/fluid dispensing region (6) of the flexible wall (2) and, in its interior, has a severing element (8). At least the severing element (8) can be pushed forward in the direction of the sample removal region/fluid dispensing region (6) in order to remove the samples and in order to introduce fluids, in such a way that the wall (2) can be perforated within the sample removal region/fluid dispensing region (6). The system (1) comprises containers, bags or tubes for filling, mixing, transporting, storage of media, such as biological liquids, sera, buffers, ultra-pure water and can be used as biological reactors or cell culture vessels in the pharmaceutical and biotechnical industry.
摘要翻译： 本发明公开了一种用于从具有柔性壁的系统中去除样品或将流体从/进入系统的装置。 取样器/流体分配器（3）在其外部固定有其基部（5）的连接区域（4）在柔性壁（2）的样品移除区域/流体分配区域（6）上，并且在其内部 ，具有切断要素（8）。 至少切断元件（8）可以沿着样品移除区域/流体分配区域（6）的方向向前推动，以便去除样品并且以这样的方式引入流体：壁（2） 可以在样品去除区域/流体分配区域（6）内穿孔。 系统（1）包括用于填充，混合，运输，储存诸如生物液体，血清，缓冲液，超纯水的介质的容器，袋或管，并可用作药物和/或制剂中的生物反应器或细胞培养容器 生物工业。
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公开(公告)号：US07174228B2
公开(公告)日：2007-02-06
申请号：US11258913
申请日：2005-10-27
申请人： Michael Konrad , Dieter Schmidt
发明人： Michael Konrad , Dieter Schmidt
CPC分类号： G01D7/06 , G01D21/02 , G05B2219/23147 , G05B2219/23171 , G05B2219/25014 , G06T11/206
摘要： A display for on-site visualization of conditions of an automated process is disclosed. It comprises a display controller which at least temporarily provides a state indication signal representing a constellation of states of at least two process data signals. At least one of the two process data signals is derived from a signal generated externally to the field device. The field device has a display element which responds to a change in the state indication signal with a significant change in its appearance, thus signaling the constellation of the states of the two process data signals in a visually perceptible manner. Therefore, the field device is particularly suited for on-site monitoring of entire plants or sections thereof by operating personnel.
摘要翻译： 公开了用于现场可视化自动化处理条件的显示器。 它包括显示控制器，其至少暂时提供表示至少两个处理数据信号的状态的状态的状态指示信号。 两个处理数据信号中的至少一个是从现场设备外部产生的信号导出的。 现场设备具有显示元件，其响应状态指示信号的变化，其外观有显着变化，从而以视觉上可察觉的方式发信号通知两个处理数据信号的状态的星座图。 因此，现场设备特别适用于由操作人员对整个工厂或其部分进行现场监控。
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