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1.发明授权Oligomers of cholesterol, cholesterol sulphate and cholesterol esters and also drugs containing these 有权胆固醇，胆固醇硫酸盐和胆固醇酯的低聚物以及含有它们的药物公开(公告)号：US08318961B2
公开(公告)日：2012-11-27
申请号：US11995256
申请日：2006-07-11
申请人： Hans-Uwe Wolf
发明人： Hans-Uwe Wolf
CPC分类号： A61Q19/00 , A61K8/63 , A61Q19/007 , A61Q19/08 , C07J9/00
摘要： The invention relates to new substances which are derived from cholesterol, cholesterol sulphate and cholesterol esters of a natural, semi-synthetic or synthetic origin in that they represent oligomers with a specific type of cross-linkage of the starting substances based on cholesterol.
摘要翻译： 本发明涉及衍生自天然，半合成或合成来源的胆固醇，胆固醇硫酸酯和胆固醇酯的新物质，因为它们代表具有基于胆固醇的起始物质的特定类型交联的寡聚物。
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2.发明申请OLIGOMERS OF CHOLESTEROL, CHOLESTEROL SULPHATE AND CHOLESTEROL ESTERS AND ALSO DRUGS CONTAINING THESE 有权胆固醇，胆固醇和胆固醇酯的低聚物，还含有这些药物公开(公告)号：US20090105199A1
公开(公告)日：2009-04-23
申请号：US11995256
申请日：2006-07-11
申请人： Hans-Uwe Wolf
发明人： Hans-Uwe Wolf
CPC分类号： A61Q19/00 , A61K8/63 , A61Q19/007 , A61Q19/08 , C07J9/00
摘要： The invention relates to new substances which are derived from cholesterol, cholesterol sulphate and cholesterol esters of a natural, semi-synthetic or synthetic origin in that they represent oligomers with a specific type of cross-linkage of the starting substances based on cholesterol.
摘要翻译： 本发明涉及衍生自天然，半合成或合成来源的胆固醇，胆固醇硫酸酯和胆固醇酯的新物质，因为它们代表具有基于胆固醇的起始物质的特定类型交联的寡聚物。
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3.发明申请CERAMIDE DIMERS AND USE THEREOF AS PHARMACEUTICAL PREPARATION OR COSMETIC PREPARATION 审中-公开陶瓷二聚体及其作为药物制备或化妆品制备的用途公开(公告)号：US20120129933A1
公开(公告)日：2012-05-24
申请号：US13380789
申请日：2010-06-23
申请人： Hans-Uwe Wolf
发明人： Hans-Uwe Wolf
IPC分类号： A61K31/225 , A61K31/164 , A61P17/00 , C07C233/09
CPC分类号： C07C235/08 , A61Q19/00 , C07C233/16 , C07C233/18 , C07C233/20 , C07C233/34
摘要： The invention relates to ceramide dimers which are constructed from two ceramide molecules which are crosslinked to each other via their lipophilic end. The ceramide molecules thereby have at least one hydrophilic group at their hydrophilic end for increasing the hydration shell of the dimer. The ceramide dimers according to the invention can be used as pharmaceutical preparation or as cosmetic preparation.
摘要翻译： 本发明涉及由两个神经酰胺分子构成的神经酰胺二聚体，它们通过它们的亲脂末端相互交联。 因此，神经酰胺分子在其亲水端具有至少一个亲水基团以增加二聚体的水合壳。 根据本发明的神经酰胺二聚体可以用作药物制剂或作为化妆品制剂。
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公开(公告)号：US20060083748A1
公开(公告)日：2006-04-20
申请号：US10518111
申请日：2003-06-04
申请人： Hans-Uwe Wolf , Jorg Dormann
发明人： Hans-Uwe Wolf , Jorg Dormann
摘要： The invention relates to an active substance excipient system, wherein the excipients are selected from the group of calixarenes or resorcinarenes. Said macromolecular excipients serve for transport of the active substance to the location of action and to a dosage and time-defined release of the same there. Metabolism, kinetics and release mechanism can be controlled by chemically modifying the excipient in a purposeful manner.
摘要翻译： 本发明涉及活性物质赋形剂体系，其中赋形剂选自杯芳烃或间苯二酚。 所述大分子赋形剂用于将活性物质转运到作用位置，并将其与其相同的剂量和定时释放。 代谢，动力学和释放机制可以通过以有目的的方式化学改性赋形剂来控制。
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5.发明授权Ceramide dimers and use thereof as pharmaceutical preparation or cosmetic preparation 有权神经酰胺二聚体及其用作药物制剂或化妆品制剂公开(公告)号：US09018405B2
公开(公告)日：2015-04-28
申请号：US13380789
申请日：2010-06-23
申请人： Hans-Uwe Wolf
发明人： Hans-Uwe Wolf
IPC分类号： C07C233/09 , C07C235/08 , C07C233/16 , C07C233/18 , C07C233/34 , C07C233/20 , A61Q19/00
CPC分类号： C07C235/08 , A61Q19/00 , C07C233/16 , C07C233/18 , C07C233/20 , C07C233/34
摘要： The invention relates to ceramide dimers which are constructed from two ceramide molecules which are crosslinked to each other via their lipophilic end. The ceramide molecules thereby have at least one hydrophilic group at their hydrophilic end for increasing the hydration shell of the dimer. The ceramide dimers according to the invention can be used as pharmaceutical preparation or as cosmetic preparation.
摘要翻译： 本发明涉及由两个神经酰胺分子构成的神经酰胺二聚体，它们通过它们的亲脂末端相互交联。 因此，神经酰胺分子在其亲水端具有至少一个亲水基团以增加二聚体的水合壳。 根据本发明的神经酰胺二聚体可以用作药物制剂或作为化妆品制剂。
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6.发明申请HYBRID MOLECULES MADE OF LIPIDS AND LIPID-ANALOGOUS COMPOUNDS AND USE THEREOF AS PHARMACEUTICAL OR COSMETIC PREPARATION 审中-公开脂肪和脂类化合物的混合分子及其作为药物或化妆品制剂的用途公开(公告)号：US20120329737A1
公开(公告)日：2012-12-27
申请号：US13380784
申请日：2010-06-23
申请人： Hans-Uwe Wolf
发明人： Hans-Uwe Wolf
IPC分类号： C07C233/18 , C07H15/06 , C07C57/00 , C07J1/00 , C07C215/24 , A61P17/00 , A61K31/685 , A61K31/7028 , A61K31/20 , A61K31/56 , A61K31/133 , C07F9/09 , A61K31/164
CPC分类号： C07J9/00 , C07J31/006 , C07J41/0055 , C07J51/00
摘要： The invention relates to hybrid molecules made of two lipids or lipid-analogous compounds which are linked to each other via their lipophilic end. The hybrid molecules thereby have at least one hydrophilic group at their hydrophilic end for increasing the hydration shell of the hybrid molecule. The hybrid molecules according to the invention can be used as pharmaceutical or as a cosmetic preparation.
摘要翻译： 本发明涉及通过其亲脂末端彼此连接的两种脂质或脂类 - 类似物形成的杂交分子。 因此，混合分子在其亲水端具有至少一个亲水基团以增加杂化分子的水合壳。 根据本发明的杂化分子可以用作药物或化妆品制剂。
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