公开(公告)号：US20080050377A1

公开(公告)日：2008-02-28

申请号：US10553491

申请日：2004-04-16

申请人： Heidi Ackerly ,  Avi Ashkenazi ,  David Eberhard ,  Gretchen Frantz ,  Dorothy French ,  Germaine G. Fuh ,  Jo-Anne S. Hongo ,  Chingwei V. Lee ,  Scot A. Marsters ,  Helga A. Raab ,  Evgeny Varfolomeev ,  Beni B. Wolf ,  Robert Maurice Pitti ,  Liliana Soroceanu

发明人： Heidi Ackerly ,  Avi Ashkenazi ,  David Eberhard ,  Gretchen Frantz ,  Dorothy French ,  Germaine G. Fuh ,  Jo-Anne S. Hongo ,  Chingwei V. Lee ,  Scot A. Marsters ,  Helga A. Raab ,  Evgeny Varfolomeev ,  Beni B. Wolf ,  Robert Maurice Pitti ,  Liliana Soroceanu

IPC分类号： C07K16/30 ,  A61K39/395 ,  A61P35/00 ,  C12N1/00 ,  C12N15/63 ,  G01N33/574 ,  G01N33/53 ,  C12N15/13 ,  C07K14/435 ,  C07K16/18

CPC分类号： C07K16/32 ,  C07K16/22 ,  C07K16/4283 ,  C07K2317/24 ,  C07K2317/54 ,  C07K2317/55 ,  C07K2317/565 ,  C07K2317/622

摘要： The present invention provides novel polypeptides, antibodies, antagonists, agonists, potentiators, nucleic acid molecules, compositions and methods relating to the STOP-1 polypeptide that are useful for treating and preventing diseases and for medical diagnosis and research. The present invention also provides consensus sequences and specific sequences for antibodies that specifically bind to STOP-1 that are useful in the methods described herein.

摘要翻译： 本发明提供了可用于治疗和预防疾病和医学诊断和研究的新型多肽，抗体，拮抗剂，激动剂，增效剂，核酸分子，与STOP-1多肽相关的组合物和方法。 本发明还提供了与本文所述方法有用的特异性结合STOP-1的抗体的共有序列和特异性序列。

公开(公告)号：US20110112279A1

公开(公告)日：2011-05-12

申请号：US12845470

申请日：2010-07-28

申请人： HEIDI ACKERLY ,  Avi Ashkenazi ,  David Eberhard ,  Gretchen Frantz ,  Dorothy French ,  Germaine G. Fuh ,  Jo-Anne S. Hongo ,  Chingwei V. Lee ,  Scot A. Marsters ,  Helga A. Raab ,  Evgeny Varfolomeev ,  Beni B. Wolf ,  Robert Maurice Pitti ,  Liliana Soroceanu

发明人： HEIDI ACKERLY ,  Avi Ashkenazi ,  David Eberhard ,  Gretchen Frantz ,  Dorothy French ,  Germaine G. Fuh ,  Jo-Anne S. Hongo ,  Chingwei V. Lee ,  Scot A. Marsters ,  Helga A. Raab ,  Evgeny Varfolomeev ,  Beni B. Wolf ,  Robert Maurice Pitti ,  Liliana Soroceanu

IPC分类号： C07K16/18

CPC分类号： C07K16/32 ,  C07K16/22 ,  C07K16/4283 ,  C07K2317/24 ,  C07K2317/54 ,  C07K2317/55 ,  C07K2317/565 ,  C07K2317/622

摘要： The present invention provides novel polypeptides, antibodies, antagonists, agonists, potentiators, nucleic acid molecules, compositions and methods relating to the STOP-1 polypeptide that are useful for treating and preventing diseases and for medical diagnosis and research. The present invention also provides consensus sequences and specific sequences for antibodies that specifically bind to STOP-1 that are useful in the methods described herein.

摘要翻译： 本发明提供了可用于治疗和预防疾病和医学诊断和研究的新型多肽，抗体，拮抗剂，激动剂，增效剂，核酸分子，与STOP-1多肽相关的组合物和方法。 本发明还提供了与本文所述方法有用的特异性结合STOP-1的抗体的共有序列和特异性序列。

公开(公告)号：US07799899B2

公开(公告)日：2010-09-21

申请号：US10553491

申请日：2004-04-16

申请人： Heidi Ackerly ,  Avi Ashkenazi ,  David Eberhard ,  Gretchen Frantz ,  Dorothy French ,  Germaine G. Fuh ,  Jo-Anne S. Hongo ,  Chingwei V. Lee ,  Scot A. Masters ,  Helga A. Raab ,  Evgeny Varfolomeev ,  Beni B. Wolf ,  Robert Maurice Pitti ,  Liliana Soroceanu

发明人： Heidi Ackerly ,  Avi Ashkenazi ,  David Eberhard ,  Gretchen Frantz ,  Dorothy French ,  Germaine G. Fuh ,  Jo-Anne S. Hongo ,  Chingwei V. Lee ,  Scot A. Masters ,  Helga A. Raab ,  Evgeny Varfolomeev ,  Beni B. Wolf ,  Robert Maurice Pitti ,  Liliana Soroceanu

IPC分类号： C07K16/00

CPC分类号： C07K16/32 ,  C07K16/22 ,  C07K16/4283 ,  C07K2317/24 ,  C07K2317/54 ,  C07K2317/55 ,  C07K2317/565 ,  C07K2317/622

摘要： The present invention provides novel polypeptides, antibodies, antagonists, agonists, potentiators, nucleic acid molecules, compositions and methods relating to the STOP-1 polypeptide that are useful for treating and preventing diseases and for medical diagnosis and research. The present invention also provides consensus sequences and specific sequences for antibodies that specifically bind to STOP-1 that are useful in the methods described herein.

摘要翻译： 本发明提供了可用于治疗和预防疾病和医学诊断和研究的新型多肽，抗体，拮抗剂，激动剂，增效剂，核酸分子，与STOP-1多肽相关的组合物和方法。 本发明还提供了与本文所述方法有用的特异性结合STOP-1的抗体的共有序列和特异性序列。