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公开(公告)号：US07799899B2
公开(公告)日：2010-09-21
申请号：US10553491
申请日：2004-04-16
申请人： Heidi Ackerly , Avi Ashkenazi , David Eberhard , Gretchen Frantz , Dorothy French , Germaine G. Fuh , Jo-Anne S. Hongo , Chingwei V. Lee , Scot A. Masters , Helga A. Raab , Evgeny Varfolomeev , Beni B. Wolf , Robert Maurice Pitti , Liliana Soroceanu
发明人： Heidi Ackerly , Avi Ashkenazi , David Eberhard , Gretchen Frantz , Dorothy French , Germaine G. Fuh , Jo-Anne S. Hongo , Chingwei V. Lee , Scot A. Masters , Helga A. Raab , Evgeny Varfolomeev , Beni B. Wolf , Robert Maurice Pitti , Liliana Soroceanu
IPC分类号： C07K16/00
CPC分类号： C07K16/32 , C07K16/22 , C07K16/4283 , C07K2317/24 , C07K2317/54 , C07K2317/55 , C07K2317/565 , C07K2317/622
摘要： The present invention provides novel polypeptides, antibodies, antagonists, agonists, potentiators, nucleic acid molecules, compositions and methods relating to the STOP-1 polypeptide that are useful for treating and preventing diseases and for medical diagnosis and research. The present invention also provides consensus sequences and specific sequences for antibodies that specifically bind to STOP-1 that are useful in the methods described herein.
摘要翻译： 本发明提供了可用于治疗和预防疾病和医学诊断和研究的新型多肽，抗体，拮抗剂，激动剂，增效剂，核酸分子，与STOP-1多肽相关的组合物和方法。 本发明还提供了与本文所述方法有用的特异性结合STOP-1的抗体的共有序列和特异性序列。
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公开(公告)号：US20080050377A1
公开(公告)日：2008-02-28
申请号：US10553491
申请日：2004-04-16
申请人： Heidi Ackerly , Avi Ashkenazi , David Eberhard , Gretchen Frantz , Dorothy French , Germaine G. Fuh , Jo-Anne S. Hongo , Chingwei V. Lee , Scot A. Marsters , Helga A. Raab , Evgeny Varfolomeev , Beni B. Wolf , Robert Maurice Pitti , Liliana Soroceanu
发明人： Heidi Ackerly , Avi Ashkenazi , David Eberhard , Gretchen Frantz , Dorothy French , Germaine G. Fuh , Jo-Anne S. Hongo , Chingwei V. Lee , Scot A. Marsters , Helga A. Raab , Evgeny Varfolomeev , Beni B. Wolf , Robert Maurice Pitti , Liliana Soroceanu
IPC分类号： C07K16/30 , A61K39/395 , A61P35/00 , C12N1/00 , C12N15/63 , G01N33/574 , G01N33/53 , C12N15/13 , C07K14/435 , C07K16/18
CPC分类号： C07K16/32 , C07K16/22 , C07K16/4283 , C07K2317/24 , C07K2317/54 , C07K2317/55 , C07K2317/565 , C07K2317/622
摘要： The present invention provides novel polypeptides, antibodies, antagonists, agonists, potentiators, nucleic acid molecules, compositions and methods relating to the STOP-1 polypeptide that are useful for treating and preventing diseases and for medical diagnosis and research. The present invention also provides consensus sequences and specific sequences for antibodies that specifically bind to STOP-1 that are useful in the methods described herein.
摘要翻译： 本发明提供了可用于治疗和预防疾病和医学诊断和研究的新型多肽，抗体，拮抗剂，激动剂，增效剂，核酸分子，与STOP-1多肽相关的组合物和方法。 本发明还提供了与本文所述方法有用的特异性结合STOP-1的抗体的共有序列和特异性序列。
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公开(公告)号：US20110112279A1
公开(公告)日：2011-05-12
申请号：US12845470
申请日：2010-07-28
申请人： HEIDI ACKERLY , Avi Ashkenazi , David Eberhard , Gretchen Frantz , Dorothy French , Germaine G. Fuh , Jo-Anne S. Hongo , Chingwei V. Lee , Scot A. Marsters , Helga A. Raab , Evgeny Varfolomeev , Beni B. Wolf , Robert Maurice Pitti , Liliana Soroceanu
发明人： HEIDI ACKERLY , Avi Ashkenazi , David Eberhard , Gretchen Frantz , Dorothy French , Germaine G. Fuh , Jo-Anne S. Hongo , Chingwei V. Lee , Scot A. Marsters , Helga A. Raab , Evgeny Varfolomeev , Beni B. Wolf , Robert Maurice Pitti , Liliana Soroceanu
IPC分类号： C07K16/18
CPC分类号： C07K16/32 , C07K16/22 , C07K16/4283 , C07K2317/24 , C07K2317/54 , C07K2317/55 , C07K2317/565 , C07K2317/622
摘要： The present invention provides novel polypeptides, antibodies, antagonists, agonists, potentiators, nucleic acid molecules, compositions and methods relating to the STOP-1 polypeptide that are useful for treating and preventing diseases and for medical diagnosis and research. The present invention also provides consensus sequences and specific sequences for antibodies that specifically bind to STOP-1 that are useful in the methods described herein.
摘要翻译： 本发明提供了可用于治疗和预防疾病和医学诊断和研究的新型多肽，抗体，拮抗剂，激动剂，增效剂，核酸分子，与STOP-1多肽相关的组合物和方法。 本发明还提供了与本文所述方法有用的特异性结合STOP-1的抗体的共有序列和特异性序列。
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4.发明授权Platelet derived growth factor receptor supports cytomegalovirus infectivity 有权血小板衍生生长因子受体支持巨细胞病毒感染公开(公告)号：US08435510B2
公开(公告)日：2013-05-07
申请号：US12672491
申请日：2008-08-07
申请人： Charles Cobbs , Liliana Soroceanu
发明人： Charles Cobbs , Liliana Soroceanu
IPC分类号： A61K39/395 , C07K16/28
CPC分类号： C12N15/1137 , A61K31/506 , A61K31/522 , A61K31/662 , A61K31/713 , A61K39/39558 , A61K45/06 , C07K16/2863 , C07K2317/76 , C07K2317/77 , C12N15/1138 , C12N2310/14 , A61K2300/00
摘要： The disclosure relates generally to compositions and methods useful for inhibiting the infection and propagation of viral particles, particularly members of the Herpesviridae family, and more particularly to cytomegalovirus (CMV).
摘要翻译： 本公开一般涉及可用于抑制病毒颗粒，特别是疱疹病毒科家族，尤其是巨细胞病毒（CMV）的病毒颗粒的感染和繁殖的组合物和方法。
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公开(公告)号：US20080221014A1
公开(公告)日：2008-09-11
申请号：US11946449
申请日：2007-11-28
IPC分类号： A61K38/02 , C12N5/00 , A61K31/7052 , A61P35/00 , C12Q1/68
CPC分类号： A61K31/00 , A61K45/06 , G01N33/57407
摘要： The present invention is directed to methods and compositions for the diagnosis, prognosis and treatment of glioma in mammals.
摘要翻译： 本发明涉及用于哺乳动物中胶质瘤的诊断，预后和治疗的方法和组合物。
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6.发明申请PLATELET DERIVED GROWTH FACTOR RECEPTOR SUPPORTS CYTOMEGALOVIRUS INFECTIVITY 有权PLATELET衍生生长因子受体支持CYCEGEGEGOVIRUS感染公开(公告)号：US20110311523A1
公开(公告)日：2011-12-22
申请号：US12672491
申请日：2008-08-07
申请人： Charles Cobbs , Liliana Soroceanu
发明人： Charles Cobbs , Liliana Soroceanu
IPC分类号： A61K39/395 , A61K31/497 , A61P31/20 , A61K31/7105
CPC分类号： C12N15/1137 , A61K31/506 , A61K31/522 , A61K31/662 , A61K31/713 , A61K39/39558 , A61K45/06 , C07K16/2863 , C07K2317/76 , C07K2317/77 , C12N15/1138 , C12N2310/14 , A61K2300/00
摘要： The disclosure relates generally to compositions and methods useful for inhibiting the infection and propagation of viral particles, particularly members of the Herpesviridae family, and more particularly to cytomegalovirus (CMV).
摘要翻译： 本公开一般涉及可用于抑制病毒颗粒，特别是疱疹病毒科家族，尤其是巨细胞病毒（CMV）的病毒颗粒的感染和繁殖的组合物和方法。
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公开(公告)号：US08716257B2
公开(公告)日：2014-05-06
申请号：US13447249
申请日：2012-04-15
申请人： Charles Cobbs , Liliana Soroceanu
发明人： Charles Cobbs , Liliana Soroceanu
CPC分类号： C12N15/1133 , A61K38/00 , C12N15/1131 , C12N2310/11 , C12N2310/14 , C12N2310/141
摘要： The disclosure relates generally to compositions and methods useful for inhibiting the infection and propagation of viral particles, particularly members of the Herpesviridae family, and more particularly to cytomegalovirus (CMV) and methods of treating diseases and disorders, including cell proliferative disorders, associated with CMV infection.
摘要翻译： 本公开通常涉及可用于抑制病毒颗粒，特别是疱疹病毒科家族的感染和繁殖的组合物和方法，更具体地涉及巨细胞病毒（CMV）以及治疗与CMV相关的疾病和病症（包括细胞增殖性疾病）的方法 感染。
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公开(公告)号：US20120264675A1
公开(公告)日：2012-10-18
申请号：US13447249
申请日：2012-04-15
申请人： Charles Cobbs , Liliana Soroceanu
发明人： Charles Cobbs , Liliana Soroceanu
IPC分类号： A61K31/7088 , A61P29/00 , A61P35/00 , C12N5/10 , A61K38/02 , C07H21/02 , C12N15/85 , A61P9/00 , A61K31/713
CPC分类号： C12N15/1133 , A61K38/00 , C12N15/1131 , C12N2310/11 , C12N2310/14 , C12N2310/141
摘要： The disclosure relates generally to compositions and methods useful for inhibiting the infection and propagation of viral particles, particularly members of the Herpesviridae family, and more particularly to cytomegalovirus (CMV) and methods of treating diseases and disorders, including cell proliferative disorders, associated with CMV infection.
摘要翻译： 本公开通常涉及可用于抑制病毒颗粒，特别是疱疹病毒科家族的感染和繁殖的组合物和方法，更具体地涉及巨细胞病毒（CMV）以及治疗与CMV相关的疾病和病症（包括细胞增殖性疾病）的方法 感染。
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公开(公告)号：US20090269351A1
公开(公告)日：2009-10-29
申请号：US12498181
申请日：2009-07-06
IPC分类号： A61K39/395 , A61P35/00
CPC分类号： A61K31/00 , A61K45/06 , G01N33/57407
摘要： The present invention is directed to methods and compositions for the diagnosis, prognosis and treatment of glioma in mammals.
摘要翻译： 本发明涉及用于哺乳动物中胶质瘤的诊断，预后和治疗的方法和组合物。
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