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公开(公告)号:US10393662B2
公开(公告)日:2019-08-27
申请号:US15646041
申请日:2017-07-10
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY L.P.
Inventor: Zhang-Lin Zhou , Lihua Zhao , Steven J. Barcelo , Zhiyong Li
Abstract: A method for forming a surface-enhanced fluorescence spectroscopy (SEFS) apparatus may include depositing a plurality of surface-enhanced spectroscopy (SES) elements onto respective tips of a plurality of nano-fingers, wherein the nano-fingers are arranged in sufficiently close proximities to each other to enable the tips of a group of adjacent nano-fingers to come into sufficiently close proximities to each other to enable the SES elements on the tips to trap fluorescent probe molecules that are to bind with target molecules when the nano-fingers are partially collapsed.
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公开(公告)号:US09664621B2
公开(公告)日:2017-05-30
申请号:US14763510
申请日:2013-01-30
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Gary Gibson , Huei Pei Kuo , Steven J. Barcelo , Zhiyong Li
CPC classification number: G01N21/658 , G01J3/4412 , G01N21/21 , G01N2201/06113 , G01N2201/0683
Abstract: Polarization selective surface enhanced Raman spectroscopy (SERS) includes a plurality of nanofingers arranged as a SERS multimer to exhibit a polarization-dependent plasmonic mode and one or both of a stimulus source and a Raman detector. The stimulus source is to illuminate the SERS multimer with a stimulus signal and the Raman detector is to detect a Raman scattering signal emitted by an analyte in a vicinity of the SERS multimer. One or both of the Raman scattering signal has a polarization state dictated by or associated with the polarization-dependent plasmonic mode and the stimulus signal has a polarization state corresponding to the polarization-dependent plasmonic mode.
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公开(公告)号:US20150355097A1
公开(公告)日:2015-12-10
申请号:US14763491
申请日:2013-01-25
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Zhang-Lin Zhou , Zhiyong Li , Steven J. Barcelo
IPC: G01N21/65
CPC classification number: B82Y15/00 , G01N21/554 , G01N21/648 , G01N21/658 , G01N2021/651
Abstract: The present disclosure is drawn to chemical sensing devices and associated methods. In one example, a chemical sensing device can include a substrate; an elongated nanostructure having an attachment end and a free end opposite the attachment end, the attachment end affixed to the substrate and the free end including a metal; and a metal oxide coating applied to the elongated nanostructure. In one example, a functional group can be attached to the coating via a covalent bond.
Abstract translation: 本公开涉及化学感测装置和相关方法。 在一个示例中,化学感测装置可以包括基底; 细长的纳米结构,其具有附接端和与所述附接端相对的自由端,所述附接端固定到所述基底并且所述自由端包括金属; 以及施加到细长纳米结构的金属氧化物涂层。 在一个实例中,可以通过共价键将官能团连接到涂层上。
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公开(公告)号:US10520441B2
公开(公告)日:2019-12-31
申请号:US14775839
申请日:2013-03-14
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Zhiyong Li , Ning Ge , Steven J. Barcelo , Huei Pei Kuo
IPC: B82Y30/00 , G01N21/65 , B82Y35/00 , C25D1/02 , C25D1/20 , G01N21/64 , G01N27/04 , G01N27/22 , G01N33/02 , G01N33/22
Abstract: Devices to detect a substance and methods of producing such a device are disclosed. An example device to detect a substance includes a housing defining a first chamber and a substrate coupled to the housing. The substrate includes nanostructures positioned within the first chamber. The nanostructures are to react to the substance when exposed thereto. The device includes a first heater positioned within the first chamber. The heater is to heat at least a portion of the substance to ready the device for analysis.
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公开(公告)号:US20170254754A1
公开(公告)日:2017-09-07
申请号:US15604558
申请日:2017-05-24
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Gary Gibson , Huei Pei Kuo , Steven J. Barcelo , Zhiyong Li
CPC classification number: G01N21/658 , G01J3/4412 , G01N21/21
Abstract: Polarization selective surface enhanced Raman spectroscopy (SERS) includes a plurality of nanofingers arranged as a SERS multimer to exhibit a polarization-dependent plasmonic mode and one or both of a stimulus source and a Raman detector. The stimulus source is to illuminate the SERS multimer with a stimulus signal and the Raman detector is to detect a Raman scattering signal emitted by an analyte in a vicinity of the SERS multimer. One or both of the Raman scattering signal has a polarization state dictated by or associated with the polarization-dependent plasmonic mode and the stimulus signal has a polarization state corresponding to the polarization-dependent plasmonic mode.
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公开(公告)号:US09476833B2
公开(公告)日:2016-10-25
申请号:US13754404
申请日:2013-01-30
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Steven J. Barcelo , Zhiyong Li , Ansoon Kim , Zhang-Lin Zhou , Gary Gibson
CPC classification number: G01N21/658 , B82Y40/00 , Y10S977/882
Abstract: According to an example, methods for forming three-dimensional (3-D) nano-particle assemblies include depositing SES elements onto respective tips of nano-fingers, in which the nano-fingers are arranged in sufficiently close proximities to each other to enable the tips of groups of adjacent ones of the nano-fingers to come into sufficiently close proximities to each other to enable the SES elements on the tips to be bonded together when the nano-fingers are partially collapsed. The methods also include causing the nano-fingers to partially collapse toward adjacent ones of the nano-fingers to cause a plurality of SES elements on respective groups of the nano-fingers to be in relatively close proximities to each other and form respective clusters of SES elements, introducing additional particles that are to attach onto the clusters of SES elements, and causing the clusters of SES elements to detach from the nano-fingers.
Abstract translation: 根据一个实例,用于形成三维(3-D)纳米颗粒组件的方法包括将SES元件沉积到纳米手指的各个尖端上,其中纳米手指以彼此足够接近的方式排列,使得 纳米手指的相邻组的尖端彼此靠近,使得当纳米手指被部分折叠时,尖端上的SES元件能够结合在一起。 所述方法还包括使纳米指部分相对于纳米手指部分地折叠,以使纳米手指的相应组上的多个SES元件彼此相对接近并形成相应的SES簇 引入附加到SES元件簇上的附加颗粒,并使SES元件簇与纳米手指分离。
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公开(公告)号:US10067060B2
公开(公告)日:2018-09-04
申请号:US15604558
申请日:2017-05-24
Applicant: Hewlett-Packard Development Company L.P.
Inventor: Gary Gibson , Huei Pei Kuo , Steven J. Barcelo , Zhiyong Li
Abstract: Polarization selective surface enhanced Raman spectroscopy (SERS) includes a plurality of nanofingers arranged as a SERS multimer to exhibit a polarization-dependent plasmonic mode and one or both of a stimulus source and a Raman detector. The stimulus source is to illuminate the SERS multimer with a stimulus signal and the Raman detector is to detect a Raman scattering signal emitted by an analyte in a vicinity of the SERS multimer. One or both of the Raman scattering signal has a polarization state dictated by or associated with the polarization-dependent plasmonic mode and the stimulus signal has a polarization state corresponding to the polarization-dependent plasmonic mode.
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公开(公告)号:US09702821B2
公开(公告)日:2017-07-11
申请号:US14762415
申请日:2013-01-30
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Zhang-Lin Zhou , Lihua Zhao , Steven J. Barcelo , Zhiyong Li
CPC classification number: G01N21/648 , B82Y15/00 , B82Y20/00 , B82Y40/00 , G01N21/6428 , G01N21/658 , G01N2021/6441
Abstract: According to an example, methods for forming three-dimensional (3-D) nano-particle assemblies may include depositing surface-enhanced spectroscopy (SES) elements onto respective tips of nano-fingers, in which the nano-fingers are arranged in sufficiently close proximities to each other to enable the tips of groups of adjacent ones of the nano-fingers to come into sufficiently close proximities to each other to enable the SES elements on the tips to be bonded together when the nano-fingers are partially collapsed. The methods also include causing the nano-fingers to partially collapse toward adjacent ones of the nano-fingers to cause a plurality of SES elements on respective groups of the nano-fingers to be in relatively close proximities to each other and form respective clusters of SES elements, introducing additional particles that are to attach onto the clusters of SES elements, and causing the clusters of SES elements to detach from the nano-fingers.
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公开(公告)号:US20160103074A1
公开(公告)日:2016-04-14
申请号:US14968314
申请日:2015-12-14
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Gary Gibson , Zhiyong Li , Alexandre M. Bratkovski , Shih-Yuan Wang , Huei Pei Kuo , Steven J. Barcelo , Zhang-Lin Zhou
IPC: G01N21/65
CPC classification number: G01N21/658 , B82Y15/00 , G01J3/4412 , G01N2021/651 , G01N2201/06113 , Y10S977/902
Abstract: A scattering spectroscopy nanosensor includes a nanoscale-patterned sensing substrate to produce an optical scattering response signal indicative of a presence of an analyte when interrogated by an optical stimulus. The scattering spectroscopy nanosensor further includes a protective covering to cover and protect the nanoscale-patterned sensing substrate. The protective covering is to be selectably removed by exposure to an optical beam incident on the protective covering. The protective covering is to prevent the analyte from interacting with the nanoscale-patterned sensing substrate prior to being removed.
Abstract translation: 散射光谱纳米传感器包括纳米级图案化的感测衬底,以产生指示当通过光学刺激询问的分析物存在时的光学散射响应信号。 散射光谱纳米传感器还包括覆盖并保护纳米级图案化感测基板的保护覆盖层。 通过暴露在入射到保护罩上的光束可选地去除保护罩。 保护性覆盖物是在去除之前防止分析物与纳米级图案化的感测基板相互作用。
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10.
公开(公告)号:US20160003748A1
公开(公告)日:2016-01-07
申请号:US14763510
申请日:2013-01-30
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P
Inventor: Gary Gibson , Huei Pei Kuo , Steven J. Barcelo , Zhiyong Li
CPC classification number: G01N21/658 , G01J3/4412 , G01N21/21 , G01N2201/06113 , G01N2201/0683
Abstract: Polarization selective surface enhanced Raman spectroscopy (SERS) includes a plurality of nanofingers arranged as a SERS multimer to exhibit a polarization-dependent plasmonic mode and one or both of a stimulus source and a Raman detector. The stimulus source is to illuminate the SERS multimer with a stimulus signal and the Raman detector is to detect a Raman scattering signal emitted by an analyte in a vicinity of the SERS multimer. One or both of the Raman scattering signal has a polarization state dictated by or associated with the polarization-dependent plasmonic mode and the stimulus signal has a polarization state corresponding to the polarization-dependent plasmonic mode.
Abstract translation: 极化选择性表面增强拉曼光谱(SERS)包括布置为SERS多聚体的多个纳米针,以表现出偏振相关等离子体激发模式以及刺激源和拉曼检测器中的一个或两个。 刺激源是用刺激信号照亮SERS多聚体,并且拉曼检测器检测由SERS多聚体附近的分析物发射的拉曼散射信号。 拉曼散射信号中的一个或两个具有由偏振相关等离子体激发模式指示或关联的偏振状态,并且刺激信号具有对应于偏振相关等离子体激发模式的偏振状态。
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