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65 条记录 (耗时 0.033 秒)

    Method for stabilizing anti-dementia drug
    3.
    发明授权
    Method for stabilizing anti-dementia drug 有权

    公开(公告)号：US08481565B2

    公开(公告)日：2013-07-09

    申请号：US11793722

    申请日：2005-12-27

    申请人： Yosuke Ueki ,  Yasuyuki Suzuki ,  Satoshi Fujioka

    发明人： Yosuke Ueki ,  Yasuyuki Suzuki ,  Satoshi Fujioka

    IPC分类号： A01N43/42 ,  A61K9/14

    CPC分类号： A61K9/2054 ,  A61K9/1635 ,  A61K9/1652 ,  A61K9/2027 ,  A61K31/445

    摘要： The present invention provides a method for stabilizing an anti-dementia drug in a pharmaceutical composition containing the anti-dementia drug and a high molecular weight basic substance by adding a high molecular weight acidic substance to said pharmaceutical composition. Further, the present invention provides a pharmaceutical composition containing an anti-dementia drug and a high molecular basic substance in which a high molecular weight acidic substance is contained for stabilizing the anti-dementia drug. Furthermore, the present invention provides a method for manufacturing a pharmaceutical composition which comprises steps wherein a solution or suspension containing a high molecular weight acidic substance is added to a mixture of an anti-dementia drug and a high molecular weight basic substance for the sake of stabilizing the anti-dementia drug.

    Liquid supply device and recording apparatus incorporating the same
    4.
    发明授权
    Liquid supply device and recording apparatus incorporating the same 有权
    液体供应装置和包含该液体供应装置的记录装置

    公开(公告)号：US07431439B2

    公开(公告)日：2008-10-07

    申请号：US10835278

    申请日：2004-04-30

    申请人： Satoshi Fujioka

    发明人： Satoshi Fujioka

    IPC分类号： B41J2/175 ,  B41J29/38

    CPC分类号： B41J2/17523 ,  B41J2/17596

    摘要： In a device for supplying liquid from a liquid cartridge to a liquid ejection head via a liquid supply channel, a cartridge chamber accommodates the liquid cartridge. A valve is disposed between the liquid cartridge and the liquid supply channel. A control lever is adapted to be manually operated by a user to control the valve so as to connect or disconnect the liquid cartridge and the liquid supply channel.

    摘要翻译： 在用于经由液体供应通道将液体从液体盒提供到液体喷射头的装置中，盒室容纳液体盒。 阀设置在液体盒和液体供应通道之间。 控制杆适于由用户手动操作以控制阀，以便连接或断开液体盒和液体供应通道。

    Composition Containing Benzamidine Derivative and Method For Stabilizing Benzamidine Derivative
    5.
    发明申请
    Composition Containing Benzamidine Derivative and Method For Stabilizing Benzamidine Derivative 失效
    含有苄脒衍生物的组合物和稳定苄脒衍生物的方法

    公开(公告)号：US20070208016A1

    公开(公告)日：2007-09-06

    申请号：US10590976

    申请日：2005-03-04

    申请人： Yasuyuki Suzuki ,  Satoshi Fujioka

    发明人： Yasuyuki Suzuki ,  Satoshi Fujioka

    IPC分类号： A61K31/5377 ,  A61K31/496 ,  A61K31/454 ,  A61K31/4035

    CPC分类号： A61K47/02 ,  A61K9/1611 ,  A61K9/19 ,  A61K9/2077 ,  A61K31/403 ,  A61K31/4035 ,  A61K31/5377 ,  A61K33/00 ,  A61K2300/00 ,  C07D209/44

    摘要： The present invention provides a composition containing a benzamidine derivative that does not decompose even when placed under humidification conditions and a method for stabilizing a benzamidine derivative. According to the present invention, decomposition reaction of a benzamidine derivative can be suppressed by adding to a benzamidine derivative represented by general formula (I) or a pharmacologically acceptable salt thereof, at least one type of electrolyte selected from the group consisting of halide salts of alkaline metal or alkaline earth metal and alkaline metal salts or alkaline earth metal salts of perchloric acid.

    摘要翻译： 本发明提供含有即使在加湿条件下也不分解的苯甲脒衍生物的组合物和稳定苯甲脒衍生物的方法。 根据本发明，通过加入由通式（I）表示的苯甲脒衍生物或其药理学上可接受的盐，可以抑制苄脒衍生物的分解反应，至少一种选自以下的电解质： 碱金属或碱土金属和高氯酸的碱金属盐或碱土金属盐。

    Sustained release formulations
    6.
    发明申请
    Sustained release formulations 审中-公开
    缓释制剂

    公开(公告)号：US20070129402A1

    公开(公告)日：2007-06-07

    申请号：US11475255

    申请日：2006-06-27

    申请人： Yosuke Ueki ,  Satoshi Fujioka ,  Shigeru Aoki

    发明人： Yosuke Ueki ,  Satoshi Fujioka ,  Shigeru Aoki

    IPC分类号： A61K31/445

    CPC分类号： A61K9/1635 ,  A61K9/1652 ,  A61K9/2027 ,  A61K9/2054 ,  A61K31/445

    摘要： The invention provides sustained release formulations comprising donepezil, stereoisomers of donepezil, pharmaceutically acceptable salts of donepezil, or pharmaceutically acceptable salts of stereoisomers of donepezil. The formulations have desirable pharmacokinetic characteristics. Examples include AUC, Tmax, Cmax, dosage-corrected AUC, and dosage-corrected Cmax.

    摘要翻译： 本发明提供包含多奈哌齐，多奈哌齐的立体异构体，多奈哌齐的药学上可接受的盐或多奈哌齐的立体异构体的药学上可接受的盐的缓释制剂。 制剂具有所需的药代动力学特征。 实例包括AUC，Tmax，Cmax，剂量校正的AUC和剂量校正的C max。

    Composition containing anti-dementia drug
    8.
    发明申请
    Composition containing anti-dementia drug 审中-公开
    含有抗痴呆药物的组合物

    公开(公告)号：US20060160852A1

    公开(公告)日：2006-07-20

    申请号：US11317238

    申请日：2005-12-27

    申请人： Susumu Kimura ,  Yosuke Ueki ,  Satoshi Fujioka

    发明人： Susumu Kimura ,  Yosuke Ueki ,  Satoshi Fujioka

    IPC分类号： A61K31/445 ,  A61K31/13

    CPC分类号： A61K45/06 ,  A61K9/2018 ,  A61K9/209 ,  A61K31/13 ,  A61K31/445 ,  A61K2300/00

    摘要： An object of the present invention is to provide, for the case of implementing a therapeutic method in which at least two kinds of anti-dementia drugs are used together, a composition that has a good therapeutic effect on the dementia, and also gives excellent compliance. Another object of the present invention is to provide a composition containing at least two kinds of the anti-dementia drugs, for which release of the anti-dementia drugs from the composition is controlled, whereby a combined effect of the anti-dementia drugs can be achieved well. Still another object of the present invention is to provide: a composition, for which the frequency of administration and the amount taken are reduced, and hence compliance can be improved; and a method of manufacturing such a composition. According to the present invention, there are provided a composition containing at least two kinds of the anti-dementia drugs; such a composition containing at least one sustained release portion containing an anti-dementia drug; and such a composition containing at least one cholinesterase inhibitor, and at least one N-methyl-D-aspartate receptor antagonist.

    摘要翻译： 本发明的目的是提供一种治疗方法，其中至少两种抗痴呆药物一起使用，具有对痴呆具有良好治疗效果的组合物，并且还具有优异的依从性 。 本发明的另一个目的是提供一种含有至少两种抗痴呆药物的组合物，其中控制抗痴呆药物从组合物中的释放，由此抗痴呆药物的组合效果可以是 做得很好 本发明的另一个目的是提供：给药频率和使用量减少的组合物，从而可以提高顺应性; 以及制造这种组合物的方法。 根据本发明，提供含有至少两种抗痴呆药物的组合物; 这种组合物含有至少一种含有抗痴呆药物的持续释放部分; 和含有至少一种胆碱酯酶抑制剂和至少一种N-甲基-D-天冬氨酸受体拮抗剂的组合物。

    Liquid supply device and recording apparatus incorporating the same
    10.
    发明申请
    Liquid supply device and recording apparatus incorporating the same 有权
    液体供应装置和包含该液体供应装置的记录装置

    公开(公告)号：US20050041075A1

    公开(公告)日：2005-02-24

    申请号：US10835278

    申请日：2004-04-30

    申请人： Satoshi Fujioka

    发明人： Satoshi Fujioka

    IPC分类号： B41J2/175

    CPC分类号： B41J2/17523 ,  B41J2/17596

    摘要： In a device for supplying liquid from a liquid cartridge to a liquid ejection head via a liquid supply channel, a cartridge chamber accommodates the liquid cartridge. A valve is disposed between the liquid cartridge and the liquid supply channel. A control lever is adapted to be manually operated by a user to control the valve so as to connect or disconnect the liquid cartridge and the liquid supply channel.

    摘要翻译： 在用于经由液体供应通道将液体从液体盒提供到液体喷射头的装置中，盒室容纳液体盒。 阀设置在液体盒和液体供应通道之间。 控制杆适于由用户手动操作以控制阀，以便连接或断开液体盒和液体供应通道。