公开(公告)号：US20100055675A1

公开(公告)日：2010-03-04

申请号：US12550102

申请日：2009-08-28

申请人： Hiroshi KUMAMOTO ,  Kouji Sakaguchi ,  Ayumi Asaeda ,  Takehiro Hasegawa ,  Naoya Okitsu ,  Noriaki Nakajima

发明人： Hiroshi KUMAMOTO ,  Kouji Sakaguchi ,  Ayumi Asaeda ,  Takehiro Hasegawa ,  Naoya Okitsu ,  Noriaki Nakajima

IPC分类号： C12Q1/70 ,  C12N5/10 ,  C07K16/00

CPC分类号： C07K16/1027 ,  C12N2770/36211 ,  G01N33/56983 ,  G01N2333/12

摘要： Method for detecting a measles virus in an analyte, comprising forming a complex of a first monoclonal antibody being capable of binding to a first epitope of a measles virus nuclear protein and being immobilized on a solid phase, a second monoclonal antibody being capable of binding to a second epitope of a measles virus nuclear protein different from the first epitope and being labeled, and a measles virus nuclear protein contained in the analyte, on the solid phase; and detecting the measles virus based on the amount of the label of the complex formed on the solid phase, is disclosed. Membrane assay test device, and membrane assay test kit are also disclosed.

摘要翻译： 用于检测分析物中麻疹病毒的方法，包括形成能够结合麻疹病毒核蛋白的第一表位并固定在固相上的第一单克隆抗体的复合物，能够结合到 与第一表位不同，被标记的麻疹病毒核蛋白的第二表位和分析物中所含的麻疹病毒核蛋白在固相上; 并且基于在固相上形成的络合物的标签的量来检测麻疹病毒。 还公开了膜分析测试装置和膜测定试剂盒。

公开(公告)号：US20100015596A1

公开(公告)日：2010-01-21

申请号：US12505144

申请日：2009-07-17

申请人： Ayumi ASAEDA ,  Naoya Okitsu ,  Hiroshi Kumamoto ,  Kouji Sakaguchi ,  Takehiro Hasegawa

发明人： Ayumi ASAEDA ,  Naoya Okitsu ,  Hiroshi Kumamoto ,  Kouji Sakaguchi ,  Takehiro Hasegawa

IPC分类号： C12Q1/70 ,  C12M1/00 ,  C07K16/08

CPC分类号： G01N33/56983 ,  C07K16/1027 ,  G01N2333/135

摘要： A kit or an immuno-chromatographic test device for detection of respiratory syncytial virus (RSV), comprising at least an RSV F protein-recognizing anti-RSV monoclonal antibody produced by hybridoma RSF2-412. An anti-RSV monoclonal antibody recognizing an RS virus F protein, which is selected from the group consisting of an antibody produced by hybridoma RSF2-412, an antibody produced by hybridoma RSF1-1565, and an antibody produced by hybridoma RSF6-255.

摘要翻译： 用于检测呼吸道合胞病毒（RSV）的试剂盒或免疫色谱测试装置，其包含由杂交瘤RSF2-412产生的至少RSV F蛋白识别抗RSV单克隆抗体。 识别RS病毒F蛋白的抗RSV单克隆抗体，其选自由杂交瘤RSF2-412产生的抗体，由杂交瘤RSF1-1565产生的抗体和由杂交瘤RSF6-255产生的抗体。

公开(公告)号：US08865424B2

公开(公告)日：2014-10-21

申请号：US13752035

申请日：2013-01-28

申请人： Naoya Okitsu ,  Katsushi Kobayashi ,  Noriaki Nakajima ,  Masumi Murakami ,  Kouji Sakaguchi ,  Ayumi Asaeda ,  Mayumi Sugimoto

发明人： Naoya Okitsu ,  Katsushi Kobayashi ,  Noriaki Nakajima ,  Masumi Murakami ,  Kouji Sakaguchi ,  Ayumi Asaeda ,  Mayumi Sugimoto

IPC分类号： G01N33/546 ,  G01N33/68 ,  G01N33/86 ,  C07K16/34 ,  C12Q1/56 ,  C07K14/75 ,  G01N33/577 ,  C07K16/36 ,  C07K16/28 ,  G01N33/58

CPC分类号： C07K16/36 ,  C07K14/75 ,  C07K16/2803 ,  G01N33/577 ,  G01N33/586 ,  G01N33/6893 ,  G01N2333/75 ,  G01N2800/102 ,  G01N2800/224 ,  G01N2800/226 ,  G01N2800/324

摘要： The present invention relates to an anti-FDP monoclonal antibody selected from the first, second and third monoclonal antibodies having different reactivity towards FDP. The present invention also relates to a reagent and reagent kit for the measurement of FDP and a method for measurement of FDP using the anti-FDP monoclonal antibodies.

摘要翻译： 本发明涉及从FDP具有不同反应性的第一，第二和第三单克隆抗体中选择的抗FDP单克隆抗体。 本发明还涉及用于测量FDP的试剂和试剂盒以及使用抗FDP单克隆抗体测量FDP的方法。