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    Method for producing glycopeptide having sialyl sugar chain, sialyl sugar chain-added amino acid derivative to be used in same, and glycopeptide
    2.
    发明授权
    Method for producing glycopeptide having sialyl sugar chain, sialyl sugar chain-added amino acid derivative to be used in same, and glycopeptide 有权
    制备具有唾液酸糖链的糖肽的方法，用于其中的唾液酸糖链加成氨基酸衍生物和糖肽

    公开(公告)号：US09073978B2

    公开(公告)日：2015-07-07

    申请号：US14004122

    申请日：2012-03-05

    申请人： Yasuhiro Kajihara ,  Masumi Murakami ,  Kazuyuki Ishii

    发明人： Yasuhiro Kajihara ,  Masumi Murakami ,  Kazuyuki Ishii

    IPC分类号： C07H1/00 ,  C07K1/06 ,  C07K14/00 ,  C07K1/00

    CPC分类号： C07K14/001 ,  C07H1/00 ,  C07K1/006 ,  C07K1/068

    摘要： [Technical Problem]To provide a method for manufacturing that enables to obtain a targeted glycopeptide harboring a sialyl sugar chain in high yield without decomposing sialic acid at a non-reducing terminal of sugar chain when the glycopeptide is synthesized by a Boc solid phase synthesis method.[Solution to Problem]The present invention is characterized in that the Boc-sialylglycosylated amino acid derivative used in Boc solid phase synthesis method is one where the carboxyl group of the sialic acid at the sugar chain non-reducing terminal is protected with a phenacyl group.

    摘要翻译： 技术问题提供一种制造方法，当通过Boc固相合成方法合成糖肽时，能够以高产率获得含有唾液酸糖链的目标糖肽，而不会在糖链的非还原末端分解唾液酸 。 [问题的解决方案]本发明的特征在于Boc固相合成法中使用的Boc-唾液酸糖基化氨基酸衍生物，其中在糖链非还原末端的唾液酸的羧基被苯甲酰基保护 。

    IMMUNOCHROMATOGRAPHIC TEST DEVICE
    3.
    发明申请
    IMMUNOCHROMATOGRAPHIC TEST DEVICE 审中-公开
    免疫色谱测试装置

    公开(公告)号：US20090087926A1

    公开(公告)日：2009-04-02

    申请号：US12190958

    申请日：2008-08-13

    申请人： Takehiro HASEGAWA ,  Masumi Murakami ,  Takeshi Imoarai

    发明人： Takehiro HASEGAWA ,  Masumi Murakami ,  Takeshi Imoarai

    IPC分类号： G01N33/543 ,  G01N30/02

    CPC分类号： G01N33/558 ,  C07K16/4283 ,  G01N33/5306

    摘要： The invention provides an immunochromatographic test device for detecting a test substance in a sample, comprising a chromatographic membrane carrier; a sample developing member; and a labeling substance holding member; wherein a substance being capable of reacting to a human anti-mouse antibody is held in a member disposed at a position which is more upstream on the basis of the sample developing direction than the chromatographic membrane carrier, as well as an a method for detecting a test substance in a sample by using an immunochromatographic test device and a method for manufacturing an immunochromatographic test device.

    摘要翻译： 本发明提供了一种用于检测样品中测试物质的免疫色谱测试装置，包括色谱膜载体; 样品显影构件; 和标签物质保持部件; 其中能够与人抗小鼠抗体反应的物质被保持在设置在比色谱膜载体基于样本显影方向更上游的位置的构件中，以及用于检测 通过使用免疫色谱测试装置和免疫色谱测试装置的制造方法在样品中测试物质。

    Method for Producing Glycopeptide Having Sialyl Sugar Chain, Sialyl Sugar Chain-Added Amino Acid Derivative to be Used in Same, and Glycopeptide
    4.
    发明申请
    Method for Producing Glycopeptide Having Sialyl Sugar Chain, Sialyl Sugar Chain-Added Amino Acid Derivative to be Used in Same, and Glycopeptide 有权
    具有唾液酸糖链的糖肽，用于同时使用的唾液酸糖链氨基酸衍生物和糖肽的方法

    公开(公告)号：US20140058062A1

    公开(公告)日：2014-02-27

    申请号：US14004122

    申请日：2012-03-05

    申请人： Yasuhiro Kajihara ,  Masumi Murakami ,  Kazuyuki Ishii

    发明人： Yasuhiro Kajihara ,  Masumi Murakami ,  Kazuyuki Ishii

    IPC分类号： C07K14/00

    CPC分类号： C07K14/001 ,  C07H1/00 ,  C07K1/006 ,  C07K1/068

    摘要： [Technical Promblem]To provide a method for manufacturing that enables to obtain a targeted glycopeptide harboring a sialyl sugar chain in high yield without decomposing sialic acid at a non-reducing terminal of sugar chain when the glycopeptide is synthesized by a Boc solid phase synthesis method.[Solution to Problem]The present invention is characterized in that the Boc-sialylglycosylated amino acid derivative used in Boc solid phase synthesis method is one where the carboxyl group of the sialic acid at the sugar chain non-reducing terminal is protected with a phenacyl group.

    摘要翻译： [技术要点]提供一种制造方法，其能够通过Boc固相合成法合成糖肽，能够以高产率获得含有唾液酸糖链的靶糖蛋白，而不会在糖链的非还原末端分解唾液酸 。 [问题的解决方案]本发明的特征在于Boc固相合成法中使用的Boc-唾液酸糖基化氨基酸衍生物，其中在糖链非还原末端的唾液酸的羧基被苯甲酰基保护 。