摘要:
The peptide production method of the present invention produces a peptide (SEQ ID NO: 1) of a protein from Plasmodium falciparum, which is effective as a malaria vaccine. The method produces the peptide of SEQ ID NO: 1 by linking the fragments (i) through (v) shown below: (v) Asn-Asn-Asp-Xaa (SEQ ID NO: 2); (iv) Asp-Phe-Lys-Thr-Pro (SEQ ID NO: 3); (iii) Asn-Lys-Thr-Tyr-Asp-Leu (SEQ ID NO: 4); (ii) Phe-Tyr-Asn-Ser-Glu (SEQ ID NO: 5); and (i) Xaa-Ala-Ser-Glu (SEQ ID NO: 6), where ‘Xaa’ in (i) and (v) represents zero or any arbitrary number of amino acid residues.
摘要翻译:本发明的肽生产方法产生作为疟疾疫苗有效的来自恶性疟原虫的蛋白质的肽(SEQ ID NO:1)。 该方法通过连接如下所示的片段(i)至(v)产生SEQ ID NO:1的肽:(v)Asn-Asn-Asp-Xaa(SEQ ID NO:2); (iv)Asp-Phe-Lys-Thr-Pro(SEQ ID NO:3); (iii)Asn-Lys-Thr-Tyr-Asp-Leu(SEQ ID NO:4); (ii)Phe-Tyr-Asn-Ser-Glu(SEQ ID NO:5); 和(i)Xaa-Ala-Ser-Glu(SEQ ID NO:6),其中(i)和(v)中的“Xaa”表示0或任意数目的氨基酸残基。
摘要:
F The peptide production method of the present invention produces a peptide (SEQ ID NO: 1) of a protein from Plasmodium falciparum, which is effective as a malaria vaccine. The method produces the peptide of SEQ ID NO: 1 by linking the fragments (i) through (v) shown below: (v)Asn-Asn-Asp-Xaa;(SEQ ID NO: 2) (iv)Asp-Phe-Lys-Thr-Pro;(SEQ ID NO: 3) (iii)Asn-Lys-Thr-Tyr-Asp-Leu;(SEQ ID NO: 4) (ii)Phe-Tyr-Asn-Ser-Glu;(SEQ ID NO: 5) and (i)Xaa-Ala-Ser-Glu,(SEQ ID NO: 6) where ‘Xaa’ in (i) and (v) represents zero or any arbitrary number of amino acid residues.
摘要:
Disclosed are a compound represented by the general formula (I) below and a polymer compound obtained by polymerizing such a compound. R1-Gly-Lac-Pro-R2 (I) (In the formula, -Gly-Lac-Pro- represents a glycine residue represented by the formula (II) below, a lactic acid residue and a tridepsipeptide linked with a proline residue; R1 represents an amino acid, polypeptide or hydroxycarboxylic acid linked by an amide bond; and R2 represents an amino acid or polypeptide linked by an amide bond, or a hydroxycarboxylic acid linked by an ester bond.
摘要:
Disclosed are a compound represented by the general formula (I) below and a polymer compound obtained by polymerizing such a compound. R1-Gly-Lac-Pro-R2 (I): where -Gly-Lac-Pro- represents a structure represented by the following formula (II),R1 represents a hydrogen atom, or an amino acid, a polypeptide or a hydroxycarboxylic acid which are linked through an amide bond,R2 represents a hydroxyl group, or an amino acid or a polypeptide which are linked through an amide bond, or a hydroxycarboxylic acid which is linked through an ester bond.
摘要:
There is provided a temperature responsive polymer compound which comprises a repeating unit represented by the following general formula (I): —R1-Hmb-R2— (I) where, Hmb represents a valic acid residue represented by the following formula (II); R1 represents an amino acid, a polypeptide, or a hydroxy acid being linked by ester bond; R2 represents an amino acid or a polypeptide being linked by amide bond or a hydroxy acid being linked by ester bond: and wherein said polymer compound has 18 or more of amino acids residues and hydroxy acid residues in total.
摘要:
The invention provides a bioactive peptide including a partial amino acid sequence of Plasmodium falciparum enolase, and having a molecular structure compatible with a specification setting for a GMP-compliant production process. The peptide has a structure in which two peptides, each having an amino acid sequence of A01-Ala-Ser-Glu-Phe-Tyr-Asn-Ser-Glu-Asn-Lys-Thr-Tyr-Asp-Leu-Asp-Phe-Lys-Thr-Pro-Asn-Asn-Asp-A02 (SEQ ID NO: 1) or A03-Ala-Ser-Glu-Phe-Tyr-Asn-Ser-Glu-Asn-Lys-Thr-Tyr-Asp-Leu-Asp-Phe-Lys-Thr-Pro-Asn-Asn-Asp-Lys-Ser-Leu-Val-Lys-Thr-A04 (SEQ ID NO: 2) are linked by amide bonds between the respective carboxy termini of the two peptides and two amino groups of Lys in a linker peptide represented by Lys-A05-Cys-A06 and arranged in the form of a two-forked branch, wherein each of A01 to A06 represents an amino acid residue in a number of an arbitrary number including 0. The peptide preferably has a dimerized structure in which two of the above described peptides are linked by an S—S bond between the Cys residues in the linker peptide sequences included in the respective two peptides.
摘要:
In a cellular phone of the invention, a rechargeable battery is used as a power supply to feed power to a second load and a regulator via a charging current detector circuit and a charging switch when an external power is not fed. The power is converted to an optimum voltage by the regulator and fed to a CPU and a load. When the external power is fed, the rechargeable battery is recharged and the charging current is detected by the charging current detector circuit. While a variation in the load is caused by a change in the operating state of the cellular phone from the call termination ready state to conversation state, or while a variation in the second load is caused by lighting of a key backlight, the current flowing in the charging current detector circuit stays constant and the correct charging current can be detected exclusively.
摘要:
A contactless charging system is made up of an electronic device and a contactless charger 200 that recharges the electronic device in a contactless manner. The electronic device transmits a full charge command indicating completion of charge. Upon receipt of the full charge command, the contactless charger shifts to a charge stop state in which charge of the electronic device is not performed. In the charge stop state, the contactless charger generates a load check signal for checking whether or not the electronic device is placed in the contactless charger in a rechargeable state, and transmits the signal. Further, the contactless charger also generates a charge restart check command for checking whether or not the electronic device requests recharge in a charge stop state, and transmits the command.
摘要:
By automatically adjusting a gain according to the presence or absence of head set connection and a head set microphone, an electronic circuit has improved sound collecting performance and prevents the microphone from casually collecting sound. In the circuit, a voltage detecting unit (105) outputs a result of comparison between power voltage and a threshold value or a digital value of the power voltage. A control unit (106) detects the presence or absence of a head set microphone (161) based on the comparison result or the digital value of the power voltage in the voltage detecting unit (105). A gain setting unit (109) sets a gain of a value larger than that in the case where the absence of the head set connection is detected by the control unit (106), when the presence of the head set connection and the absence of the head set microphone are detected by the control unit (106). A variable amplifier (110) amplifies audio data from a body microphone (107) using the gain set by the gain setting unit (109).
摘要:
To provide a contactless charging system that provides superior usability and allows for a reduction in power consumption and a safety measure, as well as to provide an electronic device, a contactless charger, and a battery pack for an electronic device which are used in the system.A contactless charging system is made up of a mobile phone 100 that is an electronic device and a contactless charger 200 that recharges the mobile phone 100 in a contactless manner. The mobile phone 100 transmits a full charge command indicating completion of charge. Upon receipt of the full charge command, the contactless charger 200 shifts to a charge stop state in which charge of the mobile phone 100 is not performed. In the charge stop state, the contactless charger 200 generates a load check signal for checking whether or not the mobile phone 100 is placed in the contactless charger 200 in a rechargeable state, and transmits the signal. Further, the contactless charger 200 also generates a charge restart check command for checking whether or not the mobile phone 100 requests recharge in a charge stop state, and transmits the command.