公开(公告)号：US5475033A

公开(公告)日：1995-12-12

申请号：US241719

申请日：1994-05-12

申请人： Hitoshi Ohmori ,  Takahiro Ogawa ,  Fuminori Tokumochi ,  Atsushi Okumura

发明人： Hitoshi Ohmori ,  Takahiro Ogawa ,  Fuminori Tokumochi ,  Atsushi Okumura

IPC分类号： A61K31/255 ,  A61K31/165 ,  A61P27/02 ,  A61P37/08 ,  A61K31/16

CPC分类号： A61K31/165 ,  Y10S514/912

摘要： The present invention provides an anti-allergic pharmaceutical composition for ophthalmic topical administration comprising an IgE antibody production inhibitor as an active ingredient. The present invention also provides a process for producing an anti-allergic pharmaceutical composition for ophthalmic topical administration, which comprises mixing an IgE antibody production inhibitor with a pharmaceutically acceptable carrier, excipient or diluent.

摘要翻译： 本发明提供一种用于眼部局部给药的抗过敏药物组合物，其包含IgE抗体产生抑制剂作为活性成分。 本发明还提供了一种制备用于眼部局部给药的抗过敏药物组合物的方法，其包括将IgE抗体产生抑制剂与药学上可接受的载体，赋形剂或稀释剂混合。

公开(公告)号：US06922377B2

公开(公告)日：2005-07-26

申请号：US10419217

申请日：2003-04-21

申请人： Atsushi Okumura ,  Masayoshi Takehata

发明人： Atsushi Okumura ,  Masayoshi Takehata

IPC分类号： G11B21/08 ,  G11B7/00 ,  G11B7/085

CPC分类号： G11B7/08529

摘要： A CPU compares a detected moving speed with a previously set reference moving speed and when the detected moving speed is smaller than the reference moving speed, controls to increase a motor driving voltage VM to be supplied to a motor and when the detected moving speed is larger than the reference moving speed, controls to decrease the motor driving voltage VM to be supplied to the motor 4.

摘要翻译： CPU将检测到的移动速度与先前设定的基准移动速度进行比较，并且当检测到的移动速度小于基准移动速度时，控制增加要供给到电动机的电动机驱动电压VM，并且当检测到的移动速度较大时 控制使电动机驱动电压VM降低到电动机4。

公开(公告)号：US08401237B2

公开(公告)日：2013-03-19

申请号：US12816705

申请日：2010-06-16

申请人： Daiji Imai ,  Atsushi Okumura

发明人： Daiji Imai ,  Atsushi Okumura

IPC分类号： G06K9/00

CPC分类号： G06T11/00

摘要： As to each section making up of an original image, a CPU of an image processing apparatus calculates a distance from a predetermined position, for example, a center of the original image to a center of the section, sets a probability in accordance with the calculated distance, determines whether or not the section is a section where an object is to be drawn according to the set probability, and draws an object in each section which is determined as a section to be drawn.

摘要翻译： 对于构成原始图像的每个部分，图像处理装置的CPU计算从预定位置（例如原始图像的中心到该部分的中心）的距离，根据计算出的 距离，根据设定的概率确定该部分是否是要绘制对象的部分，并且绘制被确定为要绘制的部分的每个部分中的对象。

公开(公告)号：US20110269229A1

公开(公告)日：2011-11-03

申请号：US13086241

申请日：2011-04-13

申请人： Paula M. Pitha-Rowe ,  Atsushi Okumura ,  Myriam S. Kunzi

发明人： Paula M. Pitha-Rowe ,  Atsushi Okumura ,  Myriam S. Kunzi

IPC分类号： C12N5/071

CPC分类号： A61K38/1709 ,  A61K48/00 ,  C07K14/47

摘要： The instant invention provides methods for the treatment and prevention of viral infection, e.g., HIV infection, based on the discovery that viral replication utilizes the ubiquitination pathway of the host cell to replicate. Specifically, the invention provides methods for the treatment and prevention of viral infection, e.g., HIV infection, by modulation of ISG15 conjugation and deconjugation, e.g., by modulation of the activity or expression of UBP43 or UBEL-1.

摘要翻译： 基于病毒复制利用宿主细胞的泛素化途径进行复制的发现，本发明提供了用于治疗和预防病毒感染（例如HIV感染）的方法。 具体地，本发明通过调节ISG15共轭和解缀，例如通过调节UBP43或UBEL-1的活性或表达来提供治疗和预防病毒感染，例如HIV感染的方法。

公开(公告)号：US20060062124A1

公开(公告)日：2006-03-23

申请号：US11217375

申请日：2005-09-02

申请人： Atsushi Okumura

发明人： Atsushi Okumura

IPC分类号： G11B7/00

CPC分类号： G11B7/0045 ,  G11B7/00736 ,  G11B2007/0006

摘要： A recording apparatus includes an acquiring unit for acquiring, from an optical disc, disc-state information including at least information of an optical disc type, information of a recording format, and information indicating whether the optical disc has already been finalized, a first determining unit for determining, based on the information of the optical disc type and the information of the recording format in the acquired information whether the optical disc type and the recording format correspond to one of predetermined combinations, a second determining unit for determining, based on the result of determination by the first determining unit and the acquired information, whether the optical disc needs to be finalized, and a display control unit for controlling, when the second determining unit determines that the optical disc needs to be finalized, display of a message representing the need of the finalization.

公开(公告)号：US08497791B2

公开(公告)日：2013-07-30

申请号：US13468126

申请日：2012-05-10

申请人： Atsushi Okumura ,  Ryusuke Sahara ,  Mitsugu Kusunoki

发明人： Atsushi Okumura ,  Ryusuke Sahara ,  Mitsugu Kusunoki

IPC分类号： H03M1/10

CPC分类号： H03F3/45475 ,  H03F3/45928 ,  H03F2200/447 ,  H03F2203/45522 ,  H03F2203/45528 ,  H03F2203/45534 ,  H03F2203/45591 ,  H03F2203/45594 ,  H03F2203/45616

摘要： A temperature dependence adjustable operational amplifier circuit which suppresses a change in a gain caused by a change in an input voltage is provided. In an operational amplifier including a first input terminal and an output terminal, an operational amplifier having an inverting input terminal and a non-inverting input terminal, an input resistance circuit, and a feedback resistance circuit, each of the input and feedback resistor circuits has a resistor and a trimming resistor, which are different in temperature coefficient from each other, connected in series with each other, and a source-drain path of a MOS transistor included in the trimming resistor circuit is disposed between resistance and an inverting input terminal, and a substrate potential thereof is set to a potential of the inverting input terminal of the operational amplifier.

摘要翻译： 提供了抑制由输入电压变化引起的增益变化的温度依赖性可调运算放大器电路。 在包括第一输入端子和输出端子的运算放大器中，具有反相输入端子和非反相输入端子的运算放大器，输入电阻电路和反馈电阻电路，每个输入和反馈电阻电路具有 电阻和微调电阻彼此串联连接的温度系数彼此不同，并且包括在微调电阻电路中的MOS晶体管的源极 - 漏极路径被设置在电阻和反相输入端之间， 并且其衬底电位被设置为运算放大器的反相输入端的电位。

公开(公告)号：US08254230B2

公开(公告)日：2012-08-28

申请号：US12269841

申请日：2008-11-12

申请人： Atsushi Okumura

发明人： Atsushi Okumura

IPC分类号： G11B7/00

CPC分类号： G11B7/0045 ,  G11B7/00736 ,  G11B2007/0006

摘要： A recording apparatus includes an acquiring unit for acquiring, from an optical disc, disc-state information including at least information of an optical disc type, information of a recording format, and information indicating whether the optical disc has already been finalized, a first determining unit for determining, based on the information of the optical disc type and the information of the recording format in the acquired information, whether the optical disc type and the recording format correspond to one of predetermined combinations, a second determining unit for determining, based on the result of determination by the first determining unit and the acquired information, whether the optical disc needs to be finalized, and a display control unit for controlling, when the second determining unit determines that the optical disc needs to be finalized, display of a message representing the need of the finalization.

摘要翻译： 记录装置包括：获取单元，用于从光盘获取至少包括光盘类型的信息，记录格式的信息以及指示光盘是否已被最终确定的信息的盘状态信息;第一确定 单元，用于基于光盘类型的信息和所获取的信息中的记录格式的信息来确定光盘类型和记录格式是否对应于预定组合之一;第二确定单元，用于基于 由第一确定单元确定的结果和所获取的信息，是否需要最终确定光盘;以及显示控制单元，用于当第二确定单元确定需要最终确定光盘时，显示消息 代表最终确定的需要。

公开(公告)号：US20110169853A1

公开(公告)日：2011-07-14

申请号：US12816693

申请日：2010-06-16

申请人： Ryota Oiwa ,  Atsushi Okumura

发明人： Ryota Oiwa ,  Atsushi Okumura

IPC分类号： G09G5/00 ,  G09G5/02

CPC分类号： G06T11/203

摘要： A CPU of an image processing apparatus detects an outline from an original image, selects from the positions in association with the detected outline a position to be drawn at a ratio in correspondence with a predetermined ratio, for example, the number of positions, and draws an object at the selected position.

摘要翻译： 图像处理装置的CPU从原始图像检测轮廓，从与所检测到的轮廓相关联的位置中以与预定比例（例如，位置数量）相对应的比例选择要绘制的位置，并绘制 在所选位置的对象。

公开(公告)号：US20100072821A1

公开(公告)日：2010-03-25

申请号：US12507660

申请日：2009-07-22

申请人： Kenichiro YAMAGUCHI ,  Atsushi Okumura ,  Mitsugu Kusunoki ,  Tomoo Murata

发明人： Kenichiro YAMAGUCHI ,  Atsushi Okumura ,  Mitsugu Kusunoki ,  Tomoo Murata

IPC分类号： H02J3/00

CPC分类号： H03M1/0643 ,  H01L27/0203 ,  H03M1/687 ,  H03M1/745 ,  H03M1/785 ,  Y10T307/696

摘要： Operating speed as well as output accuracy of a D-A converter is enhanced. With a semiconductor device including unit current sources, and unit current source switches, plural current source elements constituting each of the unit current sources are disposed so as to be evenly dispersed, thereby reducing errors of the current source element, dependent on distance while the unit current source switches are concentratedly disposed in a small region, thereby mitigating delay in operation, attributable to parasitic capacitance. In addition, with the semiconductor device including R2R resistance ladders, the R2R resistance ladder is provided on the positive and the negative of each of the unit current source switches, and the respective R2R resistance ladders are shorted with each other at respective nodes on a unit current source switch-by-unit current source switch basis, are rendered identical in length, thereby cancelling out a nonlinearity error attributable to wiring parasitic resistance.

摘要翻译： 提高了D-A转换器的工作速度和输出精度。 利用包括单位电流源和单位电流源开关的半导体器件，构成每个单位电流源的多个电流源元件被布置成均匀分散，从而根据距离减小电流源元件的误差，而单元 电流源开关集中地设置在较小的区域中，从而减轻了由寄生电容引起的工作延迟。 另外，对于包含R2R电阻梯的半导体装置，在每个单位电流源开关的正极和负极上设置R2R电阻梯，并且相应的R2R电阻梯在单元的相应节点处相互短路 电流源逐个电流源开关基础的长度相同，从而消除归因于布线寄生电阻的非线性误差。

公开(公告)号：US20090136479A1

公开(公告)日：2009-05-28

申请号：US11630544

申请日：2005-06-28

申请人： Paula M. Pitha-Rowe ,  Atsushi Okumura ,  Myriam S. Kunzi

发明人： Paula M. Pitha-Rowe ,  Atsushi Okumura ,  Myriam S. Kunzi

IPC分类号： A61K39/395 ,  C12N5/06 ,  C12N15/00

CPC分类号： A61K38/1709 ,  A61K48/00 ,  C07K14/47

摘要： The instant invention provides methods for the treatment and prevention of viral infection, e.g., HIV infection, based on the discovery that viral replication utilizes the ubiquitination pathway of the host cell to replicate. Specifically, the invention provides methods for the treatment and prevention of viral infection, e.g., HIV infection, by modulation of ISG15 conjugation and deconjugation, e.g., by modulation of the activity or expression of UBP43 or UBEL-1.

摘要翻译： 基于病毒复制利用宿主细胞的泛素化途径进行复制的发现，本发明提供了用于治疗和预防病毒感染（例如HIV感染）的方法。 具体地，本发明通过调节ISG15共轭和解缀，例如通过调节UBP43或UBEL-1的活性或表达来提供治疗和预防病毒感染，例如HIV感染的方法。