公开(公告)号：US20060262065A1

公开(公告)日：2006-11-23

申请号：US11338677

申请日：2006-01-25

申请人： Hsin Luo ,  Dong Fang ,  Ho Yang

发明人： Hsin Luo ,  Dong Fang ,  Ho Yang

IPC分类号： G09G3/36

CPC分类号： G09G3/3685 ,  G09G3/2096 ,  G09G2330/06

摘要： A timing controller for an LCD panel includes a signal receiver, a data reader, a signal receiver, a logic control unit, and a data conversion unit. The signal receiver receives transmitted signals, and the data reader acquires data from the signal receiver. The logic control unit receives the data acquired by the data reader to generate pixel data, and the data conversion unit receives the pixel data and converts them into serial signals. The timing controller converts the pixel data and the control commands into serial signals, and then they are transmitted in serial to each of the source driver chips.

摘要翻译： 用于LCD面板的时序控制器包括信号接收器，数据读取器，信号接收器，逻辑控制单元和数据转换单元。 信号接收器接收发射信号，数据读取器从信号接收器获取数据。 逻辑控制单元接收由数据读取器获取的数据以产生像素数据，并且数据转换单元接收像素数据并将其转换为串行信号。 定时控制器将像素数据和控制命令转换为串行信号，然后将它们串行发送到每个源驱动器芯片。

公开(公告)号：US08168586B1

公开(公告)日：2012-05-01

申请号：US12275779

申请日：2008-11-21

申请人： Dong Fang ,  Paul Moore ,  Steve Ruben ,  Sudeepta Aggarwal

发明人： Dong Fang ,  Paul Moore ,  Steve Ruben ,  Sudeepta Aggarwal

IPC分类号： A61K38/00 ,  G01N33/574 ,  C12Q1/68 ,  A61K51/10 ,  A61K39/00

CPC分类号： C07K16/249 ,  A61K39/39533 ,  A61K2039/505 ,  C07K14/47 ,  C07K14/57 ,  C07K16/18 ,  C07K16/30 ,  C07K2317/21 ,  C07K2317/24 ,  C07K2317/54 ,  C07K2317/55 ,  C07K2317/622 ,  C07K2317/732 ,  C07K2317/734 ,  C12N15/113 ,  C12N2310/14 ,  C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/118 ,  C12Q2600/158 ,  G01N33/5011 ,  G01N33/574 ,  G01N33/57484 ,  G01N2500/10

摘要： Methods and compositions are provided for assessing, treating, and preventing diseases, especially cancer, using cancer-associated targets (“CAT”). Methods and compositions are also provided for determining or predicting the effectiveness of a treatment for these diseases or for selecting a treatment, using CAT. Methods and compositions are further provided for modulating cell function using CAT. Also provided are compositions that modulate CAT (e.g., antagonists or agonists), such as antibodies, proteins, small molecule compounds, and nucleic acid agents (e.g., RNAi and antisense agents), as well as pharmaceutical compositions thereof. Further provided are methods of screening for agents that modulate CAT, and agents identified by these screening methods.

摘要翻译： 提供了使用癌症相关靶标（“CAT”）评估，治疗和预防疾病，特别是癌症的方法和组合物。 还提供了用于确定或预测这些疾病的治疗或使用CAT选择治疗的有效性的方法和组合物。 还提供了使用CAT调节细胞功能的方法和组合物。 还提供了调节CAT（例如拮抗剂或激动剂）如抗体，蛋白质，小分子化合物和核酸试剂（例如RNAi和反义试剂）的组合物及其药物组合物。 进一步提供了筛选调节CAT的试剂的方法，以及通过这些筛选方法鉴定的试剂。

公开(公告)号：US09533424B2

公开(公告)日：2017-01-03

申请号：US13551109

申请日：2012-07-17

申请人： Florina Winter ,  Chunfang Song ,  Dong Fang ,  RanMin Wang ,  Brian William Cataldo ,  Jing Jun Xia

发明人： Florina Winter ,  Chunfang Song ,  Dong Fang ,  RanMin Wang ,  Brian William Cataldo ,  Jing Jun Xia

IPC分类号： B26B21/52

CPC分类号： B26B21/521 ,  B26B21/522 ,  B26B21/528 ,  Y10T16/476 ,  Y10T29/49 ,  Y10T29/49826

摘要： A razor handle includes an at least partially hollow elongated structure and an at least partially hollow sleeve. The elongated structure has an interior surface and an exterior surface, a first opening at a proximate end, and a second opening along a length of the elongated structure. The sleeve has an interior surface and an exterior surface with a protrusion. The protrusion is adapted to extend through the second opening to the exterior surface of the elongated structure forming a gripping member.

摘要翻译： 剃刀手柄包括至少部分中空的细长结构和至少部分中空的套筒。 细长结构具有内表面和外表面，在近端处的第一开口和沿着细长结构的长度的第二开口。 套筒具有内表面和具有突起的外表面。 该突起适于延伸通过第二开口延伸到形成夹持构件的细长结构的外表面。

公开(公告)号：US08524238B2

公开(公告)日：2013-09-03

申请号：US13436411

申请日：2012-03-30

申请人： Dong Fang ,  Paul Moore ,  Steve Ruben ,  Sudeepta Aggarwal

发明人： Dong Fang ,  Paul Moore ,  Steve Ruben ,  Sudeepta Aggarwal

IPC分类号： A61K39/395 ,  A61K39/00

CPC分类号： C07K16/249 ,  A61K39/39533 ,  A61K2039/505 ,  C07K14/47 ,  C07K14/57 ,  C07K16/18 ,  C07K16/30 ,  C07K2317/21 ,  C07K2317/24 ,  C07K2317/54 ,  C07K2317/55 ,  C07K2317/622 ,  C07K2317/732 ,  C07K2317/734 ,  C12N15/113 ,  C12N2310/14 ,  C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/118 ,  C12Q2600/158 ,  G01N33/5011 ,  G01N33/574 ,  G01N33/57484 ,  G01N2500/10

摘要： Methods and compositions are provided for assessing, treating, and preventing diseases, especially cancer, using cancer-associated targets (“CAT”). Methods and compositions are also provided for determining or predicting the effectiveness of a treatment for these diseases or for selecting a treatment, using CAT. Methods and compositions are further provided for modulating cell function using CAT. Also provided are compositions that modulate CAT (e.g., antagonists or agonists), such as antibodies, proteins, small molecule compounds, and nucleic acid agents (e.g., RNAi and antisense agents), as well as pharmaceutical compositions thereof. Further provided are methods of screening for agents that modulate CAT, and agents identified by these screening methods.

摘要翻译： 提供了使用癌症相关靶标（“CAT”）评估，治疗和预防疾病，特别是癌症的方法和组合物。 还提供了用于确定或预测这些疾病的治疗或使用CAT选择治疗的有效性的方法和组合物。 还提供了使用CAT调节细胞功能的方法和组合物。 还提供了调节CAT（例如拮抗剂或激动剂）如抗体，蛋白质，小分子化合物和核酸试剂（例如RNAi和反义试剂）的组合物及其药物组合物。 进一步提供了筛选调节CAT的试剂的方法，以及通过这些筛选方法鉴定的试剂。

公开(公告)号：US20120279039A1

公开(公告)日：2012-11-08

申请号：US13551109

申请日：2012-07-17

申请人： Florina Winter ,  Chunfang Song ,  Dong Fang ,  RanMin Wang ,  Brian William Cataldo ,  Jing Jun Xia

发明人： Florina Winter ,  Chunfang Song ,  Dong Fang ,  RanMin Wang ,  Brian William Cataldo ,  Jing Jun Xia

IPC分类号： B26B21/52 ,  B29C45/14 ,  B29C65/00 ,  B23P17/00

CPC分类号： B26B21/521 ,  B26B21/522 ,  B26B21/528 ,  Y10T16/476 ,  Y10T29/49 ,  Y10T29/49826

摘要： A razor handle includes an at least partially hollow elongated structure and an at least partially hollow sleeve. The elongated structure has an interior surface and an exterior surface, a first opening at a proximate end, and a second opening along a length of the elongated structure. The sleeve has an interior surface and an exterior surface with a protrusion. The protrusion is adapted to extend through the second opening to the exterior surface of the elongated structure forming a gripping member.

摘要翻译： 剃刀手柄包括至少部分中空的细长结构和至少部分中空的套筒。 细长结构具有内表面和外表面，在近端处的第一开口和沿着细长结构的长度的第二开口。 套筒具有内表面和具有突起的外表面。 该突起适于延伸通过第二开口延伸到形成夹持构件的细长结构的外表面。

公开(公告)号：US20120260509A1

公开(公告)日：2012-10-18

申请号：US13444886

申请日：2012-04-12

申请人： Dong Fang ,  Florina Winter ,  Ashok Bakul Patel ,  Rache Jane Otter ,  Matthias Richard Hien ,  Andrew Anthony Szczepanowski

发明人： Dong Fang ,  Florina Winter ,  Ashok Bakul Patel ,  Rache Jane Otter ,  Matthias Richard Hien ,  Andrew Anthony Szczepanowski

IPC分类号： B26B21/52 ,  B25G1/10

CPC分类号： B26B21/52 ,  Y10T16/466

摘要： A hand held device comprising a handle, said handle comprising a grip portion and a connection portion, said connection portion rotating with respect to said grip portion about a rotational axis, said connection portion forming a docking portion suitable for receiving an optional head unit, said docking portion being positioned opposite distally away from said grip portion, wherein rotation of the connection portion relative to the grip portion generates a specific amount of dynamic torsional resistance. The handle has a set amount of stiffness and damping and/or stiffness and momentum of inertia such that the device provides a controlled return during rotation about the rotational axis so the device can contour about the surface in a desirable manner.

摘要翻译： 一种手持式装置，包括手柄，所述手柄包括握持部分和连接部分，所述连接部分围绕旋转轴线相对于所述抓握部分旋转，所述连接部分形成适于接收可选头部单元的对接部分，所述对接部分 对接部分远离所述把手部分定位成相对于所述连接部分相对于所述把手部分的旋转产生特定量的动态扭转阻力。 手柄具有一定量的刚度和阻尼和/或刚度和惯性动量，使得该装置在围绕旋转轴线旋转期间提供受控的返回，因此该装置可以以期望的方式围绕该表面轮廓。

公开(公告)号：US20100005669A1

公开(公告)日：2010-01-14

申请号：US12323503

申请日：2008-11-26

申请人： Florina Winter ,  Chunfang Song ,  Dong Fang ,  RanMin Wang ,  Brian William Cataldo ,  Jing Jun Xia

发明人： Florina Winter ,  Chunfang Song ,  Dong Fang ,  RanMin Wang ,  Brian William Cataldo ,  Jing Jun Xia

IPC分类号： B26B21/00

CPC分类号： B26B21/521 ,  B26B21/522 ,  B26B21/528 ,  Y10T16/476 ,  Y10T29/49 ,  Y10T29/49826

摘要： A razor handle includes an at least partially hollow elongated structure and an at least partially hollow sleeve. The elongated structure has an interior surface and an exterior surface, a first opening at a proximate end, and a second opening along a length of the elongated structure. The sleeve has an interior surface and an exterior surface with a protrusion. The protrusion is adapted to extend through the second opening to the exterior surface of the elongated structure forming a gripping member.

摘要翻译： 剃刀手柄包括至少部分中空的细长结构和至少部分中空的套筒。 细长结构具有内表面和外表面，在近端处的第一开口和沿着细长结构的长度的第二开口。 套筒具有内表面和具有突起的外表面。 该突起适于延伸通过第二开口延伸到形成夹持构件的细长结构的外表面。

公开(公告)号：US06613534B2

公开(公告)日：2003-09-02

申请号：US09812348

申请日：2001-03-20

申请人： Vijayasaradhi Setaluri ,  Dong Fang ,  Wain White

发明人： Vijayasaradhi Setaluri ,  Dong Fang ,  Wain White

IPC分类号： G01N33574

CPC分类号： G01N33/574 ,  Y10S435/975

摘要： The invention relates to detection of MAP-2 (microtubule associated protein-2) as a marker to determine the metastatic potential of a tumor, including tumors derived from the neural crest such as melanomas, gliomas, Schwanomas, chromocytomas and small cell lung cancer. In one aspect, the invention comprises a method for determining the metastatic potential of a tumor sample, wherein decreased levels of MAP-2 expression in a test sample relative to controls indicates that the sample has increased metastatic potential as compared to the control. In another aspect, the invention comprises a method to prevent tumor progression in metastatic melanoma by increasing levels of MAP-2 protein in cells.