公开(公告)号：US08617587B2

公开(公告)日：2013-12-31

申请号：US12630422

申请日：2009-12-03

申请人： Hubert Thoma ,  Uwe Thomas Schote ,  Ute Isele

发明人： Hubert Thoma ,  Uwe Thomas Schote ,  Ute Isele

IPC分类号： A61K9/20

CPC分类号： A61K9/5026 ,  A61K9/2081

摘要： The present invention relates to the supply and production of an animal medicine consisting of a substrate in pellet or tablet form, which is attractive to livestock and domestic animals, in which fine-grained particles of a neutral-tasting, physiologically compatible, solid carrier material are embedded, which is characterized in that said fine-grained particles of carrier material have an average diameter of 0.09 to 0.8 mm and are coated with an active substance from veterinary medicine, and said active substance layer is covered with a protective layer of a physiologically compatible polymer matrix, and to the production of this animal medicine. It also relates to the usage of said double-coated, fine-grained particles of carrier material in the production of a preparation for veterinary medicine.

摘要翻译： 本发明涉及一种动物药物的供应和生产，该药物由颗粒或片剂形式的基质组成，其对家畜和家畜具有吸引力，其中中性品味，生理上相容的固体载体材料的细粒颗粒 其特征在于，所述载体材料的细粒颗粒的平均直径为0.09至0.8mm，并且由兽医药物涂覆活性物质，并且所述活性物质层被生理学上的保护层覆盖 相容的聚合物基质，以及该动物药物的生产。 它还涉及在制备兽药制剂中使用载体材料的所述双重涂层细粒颗粒。

公开(公告)号：US20100074952A1

公开(公告)日：2010-03-25

申请号：US12630422

申请日：2009-12-03

申请人： Hubert Thoma ,  Uwe Thomas Schote ,  Ute Isele

发明人： Hubert Thoma ,  Uwe Thomas Schote ,  Ute Isele

IPC分类号： A61K9/32 ,  A61K31/55 ,  A61K9/50 ,  A61P9/10

CPC分类号： A61K9/5026 ,  A61K9/2081

摘要： The present invention relates to the supply and production of an animal medicine consisting of a substrate in pellet or tablet form, which is attractive to livestock and domestic animals, in which fine-grained particles of a neutral-tasting, physiologically compatible, solid carrier material are embedded, which is characterised in that said fine-grained particles of carrier material have an average diameter of 0.09 to 0.8 mm and are coated with an active substance from veterinary medicine, and said active substance layer is covered with a protective layer of a physiologically compatible polymer matrix, and to the production of this animal medicine. It also relates to the usage of said double-coated, fine-grained particles of carrier material in the production of a preparation for veterinary medicine.

摘要翻译： 本发明涉及一种动物药物的供应和生产，该药物由颗粒或片剂形式的基质组成，其对家畜和家畜具有吸引力，其中中性品味，生理上相容的固体载体材料的细粒颗粒 其特征在于，所述载体材料的细粒颗粒的平均直径为0.09至0.8mm，并且由兽医药物涂覆活性物质，并且所述活性物质层被生理学上的保护层覆盖 相容的聚合物基质，以及该动物药物的生产。 它还涉及在制备兽药制剂中使用载体材料的所述双重涂层细粒颗粒。

公开(公告)号：US20050169971A1

公开(公告)日：2005-08-04

申请号：US10506937

申请日：2003-03-10

申请人： Hubert Thoma ,  Uwe Schote ,  Ute Isele

发明人： Hubert Thoma ,  Uwe Schote ,  Ute Isele

IPC分类号： A61K9/00 ,  A61K9/20 ,  A61K9/26 ,  A61K9/50 ,  A61K31/55 ,  A61K47/02 ,  A61K47/06 ,  A61K47/26 ,  A61K47/32 ,  A61K47/34 ,  A61K47/36 ,  A61K47/38 ,  A61K47/42 ,  A61K47/44 ,  A61P25/00 ,  A61P31/04 ,  A61P31/12 ,  A61P33/00 ,  A61P43/00 ,  A23K1/165 ,  A23K1/17

CPC分类号： A61K9/5026 ,  A61K9/2081

摘要： The present invention relates to the supply and production of an animal medicine consisting of a substrate in pellet or tablet form, which is attractive to livestock and domestic animals, in which fine-grained particles of a neutral-tasting, physiologically compatible, solid carrier material are embedded, which is characterised in that said fine-grained particles of carrier material have an average diameter of 0.09 to 0.8 mm and are coated with an active substance from veterinary medicine, and said active substance layer is covered with a protective layer of a physiologically compatible polymer matrix, and to the production of this animal medicine. It also relates to the usage of said double-coated, fine-grained particles of carrier material in the production of a preparation for veterinary medicine.

摘要翻译： 本发明涉及一种动物药物的供应和生产，该药物由颗粒或片剂形式的基质组成，其对家畜和家畜具有吸引力，其中中性品味，生理上相容的固体载体材料的细粒颗粒 其特征在于，所述载体材料的细粒颗粒的平均直径为0.09至0.8mm，并且由兽医药物涂覆活性物质，并且所述活性物质层被生理学上的保护层覆盖 相容的聚合物基质，以及该动物药物的生产。 它还涉及在制备兽药制剂中使用载体材料的所述双重涂层细粒颗粒。

公开(公告)号：US08628794B2

公开(公告)日：2014-01-14

申请号：US10564339

申请日：2004-07-29

申请人： Ute Isele

发明人： Ute Isele

IPC分类号： A61K9/28 ,  A61K31/335 ,  A61K31/34 ,  A61K9/00 ,  A23K1/00 ,  A23K1/18 ,  A23K1/17

CPC分类号： A61K9/0056 ,  A23K20/163 ,  A23K20/195 ,  A23K40/20 ,  A23K50/42 ,  A61K31/17 ,  A61K31/365 ,  A61K31/4985 ,  A61K38/13 ,  A61K47/10 ,  A61K47/36

摘要： The present invention is directed to palatable ductile chewable veterinary composition for oral administration. The composition is capable of killing endo-parasites and ecto-parasites and/or can be used for treating prophylactic or curative animal diseases, and it is useful for the treatment of any warm-blooded non-human animal, including herd animals, like horses, cattle, sheep or poultry and preferably pets like dogs and cats. It consists basically of (A) an effective amount of one or more ingredients that are active against animal pests, pathogens or animal diseases; (B) meat flavoring; (C) partially gelatinized starch; (D) a softener; and (E) up to 9% water.

摘要翻译： 本发明涉及用于口服给药的适口韧性咀嚼型兽用组合物。 该组合物能够杀死内寄生虫和寄生虫和/或可用于治疗预防性或治疗性动物疾病，并且它可用于治疗任何温血非人动物，包括畜群动物，如马 ，牛，羊或家禽，最好是宠物，如狗和猫。 它基本上由（A）有效量的一种或多种对动物有害生物，病原体或动物疾病起作用的成分组成; （B）肉调味; （C）部分糊化淀粉; （D）软化剂; 和（E）多达9％的水。

公开(公告)号：US20090292013A1

公开(公告)日：2009-11-26

申请号：US11721133

申请日：2005-12-13

申请人： Caroline Sautter ,  Ute Isele

发明人： Caroline Sautter ,  Ute Isele

IPC分类号： A61K31/35 ,  A61K47/30

CPC分类号： A61K9/0024 ,  A61K31/35 ,  A61K47/10 ,  A61K47/34

摘要： The invention relates to a composition, comprising a thermoplastic polymer, a rate modifying agent and a biologically active agent, useful as a slow-release drug-delivery implant in the body of a human or animal that can be administered in liquid form into the body.

摘要翻译： 本发明涉及一种组合物，其包含热塑性聚合物，速率改性剂和生物活性剂，其可用作可以以液体形式施用于体内的人或动物身体中的缓释药物递送植入物 。

公开(公告)号：US20060222684A1

公开(公告)日：2006-10-05

申请号：US10564339

申请日：2004-07-29

申请人： Ute Isele

发明人： Ute Isele

IPC分类号： A01N43/04 ,  A23K1/165

CPC分类号： A61K9/0056 ,  A23K20/163 ,  A23K20/195 ,  A23K40/20 ,  A23K50/42 ,  A61K31/17 ,  A61K31/365 ,  A61K31/4985 ,  A61K38/13 ,  A61K47/10 ,  A61K47/36

摘要： The present invention is directed to palatable ductile chewable veterinary composition for oral administration. The composition is capable of killing endo-parasites and ecto-parasites and/or can be used for treating prophylactic or curative animal diseases, and it is useful for the treatment of any warm-blooded non-human animal, including herd animals, like horses, cattle, sheep or poultry and preferably pets like dogs and cats. It consists basically of (A) an effective amount of one or more ingredients that are active against animal pests, pathogens or animal diseases; (B) meat flavoring; (C) partially gelatinized starch; (D) a softener; and (E) up to 9% water.

公开(公告)号：US20140094418A1

公开(公告)日：2014-04-03

申请号：US14103373

申请日：2013-12-11

申请人： Ute Isele

发明人： Ute Isele

IPC分类号： A61K9/00 ,  A61K38/13 ,  A61K47/10 ,  A61K31/17 ,  A61K47/36 ,  A61K31/4985 ,  A61K31/365

CPC分类号： A61K9/0056 ,  A23K20/163 ,  A23K20/195 ,  A23K40/20 ,  A23K50/42 ,  A61K31/17 ,  A61K31/365 ,  A61K31/4985 ,  A61K38/13 ,  A61K47/10 ,  A61K47/36

摘要： The present invention is directed to palatable ductile chewable veterinary composition for oral administration. The composition is capable of killing endo-parasites and ecto-parasites and/or can be used for treating prophylactic or curative animal diseases, and it is useful for the treatment of any warm-blooded non-human animal, including herd animals, like horses, cattle, sheep or poultry and preferably pets like dogs and cats. It consists basically of (A) an effective amount of one or more ingredients that are active against animal pests, pathogens or animal diseases; (B) meat flavoring; (C) partially gelatinized starch; (D) a softener; and (E) up to 9% water.

摘要翻译： 本发明涉及用于口服给药的适口韧性咀嚼型兽用组合物。 该组合物能够杀死内寄生虫和寄生虫和/或可用于治疗预防性或治疗性动物疾病，并且它可用于治疗任何温血非人动物，包括畜群动物，如马 ，牛，羊或家禽，最好是宠物，如狗和猫。 它基本上由（A）有效量的一种或多种对动物有害生物，病原体或动物疾病起作用的成分组成; （B）肉调味; （C）部分糊化淀粉; （D）软化剂; 和（E）多达9％的水。

公开(公告)号：US08541019B2

公开(公告)日：2013-09-24

申请号：US13285724

申请日：2011-10-31

申请人： Ute Isele

发明人： Ute Isele

IPC分类号： A61K9/28 ,  A61K31/335 ,  A61K31/34 ,  A61K9/00 ,  A23K1/00 ,  A23K1/18 ,  A23K1/17

CPC分类号： A61K9/0056 ,  A23K20/163 ,  A23K20/195 ,  A23K40/20 ,  A23K50/42 ,  A61K31/17 ,  A61K31/365 ,  A61K31/4985 ,  A61K38/13 ,  A61K47/10 ,  A61K47/36

摘要： The present invention is directed to palatable ductile chewable veterinary composition for oral administration. The composition is capable of killing endo-parasites and ecto-parasites and/or can be used for treating prophylactic or curative animal diseases, and it is useful for the treatment of any warm-blooded non-human animal, including herd animals, like horses, cattle, sheep or poultry and preferably pets like dogs and cats. It consists basically of (A) an effective amount of one or more ingredients that are active against animal pests, pathogens or animal diseases; (B) meat flavoring; (C) partially gelatinized starch; (D) a softener; and (E) up to 9% water.

摘要翻译： 本发明涉及用于口服给药的适口韧性咀嚼型兽用组合物。 该组合物能够杀死内寄生虫和寄生虫和/或可用于治疗预防性或治疗性动物疾病，并且它可用于治疗任何温血非人动物，包括畜群动物，如马 ，牛，羊或家禽，最好是宠物，如狗和猫。 它基本上由（A）有效量的一种或多种对动物有害生物，病原体或动物疾病起作用的成分组成; （B）肉调味; （C）部分糊化淀粉; （D）软化剂; 和（E）多达9％的水。

公开(公告)号：US20120046296A1

公开(公告)日：2012-02-23

申请号：US13285724

申请日：2011-10-31

申请人： Ute Isele

发明人： Ute Isele

IPC分类号： A61K31/4985 ,  A61P33/00 ,  A61P31/00 ,  A61K31/365

CPC分类号： A61K9/0056 ,  A23K20/163 ,  A23K20/195 ,  A23K40/20 ,  A23K50/42 ,  A61K31/17 ,  A61K31/365 ,  A61K31/4985 ,  A61K38/13 ,  A61K47/10 ,  A61K47/36

摘要： The present invention is directed to palatable ductile chewable veterinary composition for oral administration. The composition is capable of killing endo-parasites and ecto-parasites and/or can be used for treating prophylactic or curative animal diseases, and it is useful for the treatment of any warm-blooded non-human animal, including herd animals, like horses, cattle, sheep or poultry and preferably pets like dogs and cats. It consists basically of (A) an effective amount of one or more ingredients that are active against animal pests, pathogens or animal diseases; (B) meat flavoring; (C) partially gelatinized starch; (D) a softener; and (E) up to 9% water.

摘要翻译： 本发明涉及用于口服给药的适口韧性咀嚼型兽用组合物。 该组合物能够杀死内寄生虫和寄生虫和/或可用于治疗预防性或治疗性动物疾病，并且它可用于治疗任何温血非人动物，包括畜群动物，如马 ，牛，羊或家禽，最好是宠物，如狗和猫。 它基本上由（A）有效量的一种或多种对动物有害生物，病原体或动物疾病起作用的成分组成; （B）肉调味; （C）部分糊化淀粉; （D）软化剂; 和（E）多达9％的水。

公开(公告)号：US5658898A

公开(公告)日：1997-08-19

申请号：US553126

申请日：1995-11-07

申请人： Hans Georg Weder ,  Ute Isele

发明人： Hans Georg Weder ,  Ute Isele

IPC分类号： A61K9/127 ,  A61K9/107 ,  A61K31/55 ,  A61K31/553 ,  A61K47/14 ,  A61K47/24 ,  A61P9/00 ,  A61P9/10 ,  A61P31/04 ,  A61P35/00 ,  C07D498/22

CPC分类号： A61K31/553 ,  A61K9/1075 ,  A61K9/127 ,  Y10S514/937

摘要： The invention relates to a novel advantageous dosage form for sparingly soluble staurosporin derivatives, especially N-benzoyl-staurosporin. The dosage form is administrable intravenously in the form of a nanoemulsion and comprises as solubilisers a combination of phospholipids, triglycerides and partial fatty acid esters of polyoxyethylene sorbitan.

摘要翻译： 本发明涉及一种新颖的微溶型星形孢菌素衍生物，特别是N-苯甲酰基星形孢菌素的有利剂型。 剂型以纳米乳剂的形式静脉内施用，并且包含作为增溶剂的是聚氧乙烯脱水山梨糖醇的磷脂，甘油三酸酯和部分脂肪酸酯的组合。