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公开(公告)号：US10934522B2
公开(公告)日：2021-03-02
申请号：US15974195
申请日：2018-05-08
申请人： Humacyte, Inc.
发明人： Shannon L. M. Dahl , Laura E. Niklason , Justin T. Strader , William E. Tente , Joseph J. Lundquist
IPC分类号： C12N5/00 , A61L27/34 , A61F2/06 , A61F2/04 , B29C53/00 , B29C53/36 , A61L27/16 , A61L27/18 , A61L27/36 , A61L27/38 , A61L27/54 , A61L27/58 , B29K67/00 , B29K105/00 , B29L23/00 , B29L31/00
摘要： The present invention provides constructs including a tubular biodegradable polyglycolic acid scaffold, wherein the scaffold may be coated with extracellular matrix proteins and substantially acellular. The constructs can be utilized as an arteriovenous graft, a coronary graft, a peripheral artery bypass conduit, or a urinary conduit. The present invention also provides methods of producing such constructs.
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公开(公告)号：US09657265B2
公开(公告)日：2017-05-23
申请号：US14495339
申请日：2014-09-24
申请人： Humacyte, Inc.
发明人： Shannon L. M. Dahl , Laura E. Niklason , Juliana Blum , Justin T. Strader , William E. Tente , Heather L. Prichard , Joseph J. Lundquist
IPC分类号： A61F2/06 , C12N5/00 , A61F2/04 , B29C53/00 , B29C53/36 , A61L27/34 , B29K67/00 , B29K105/00 , B29L23/00 , B29L31/00
CPC分类号： C12N5/0068 , A61F2/04 , A61F2/06 , A61F2002/047 , A61F2002/048 , A61L27/16 , A61L27/18 , A61L27/34 , A61L27/3633 , A61L27/38 , A61L27/3895 , A61L27/54 , A61L27/58 , B29C53/005 , B29C53/36 , B29K2067/043 , B29K2105/256 , B29K2995/0056 , B29K2995/006 , B29L2023/00 , B29L2031/7532 , C12N2533/30 , C12N2533/40 , Y10T156/1038 , C08L67/04
摘要： The present invention provides constructs including a tubular biodegradable polyglycolic acid scaffold, wherein the scaffold may be coated with extracellular matrix proteins and substantially acellular. The constructs can be utilized as an arteriovenous graft, a coronary graft, a peripheral artery bypass conduit, or a urinary conduit. The present invention also provides methods of producing such constructs.
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公开(公告)号：US10947498B2
公开(公告)日：2021-03-16
申请号：US16007322
申请日：2018-06-13
申请人： Humacyte, Inc.
发明人： Shannon L. M. Dahl , Laura E. Niklason , Justin T. Strader , William E. Tente , Joseph J. Lundquist
IPC分类号： C12N5/00 , A61L27/34 , A61F2/06 , A61F2/04 , B29C53/00 , B29C53/36 , A61L27/16 , A61L27/18 , A61L27/36 , A61L27/38 , A61L27/54 , A61L27/58 , B29K67/00 , B29K105/00 , B29L23/00 , B29L31/00
摘要： The present invention provides constructs including a tubular biodegradable polyglycolic acid scaffold, wherein the scaffold may be coated with extracellular matrix proteins and substantially acellular. The constructs can be utilized as an arteriovenous graft, a coronary graft, a peripheral artery bypass conduit, or a urinary conduit. The present invention also provides methods of producing such constructs.
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公开(公告)号：US09650603B2
公开(公告)日：2017-05-16
申请号：US14495310
申请日：2014-09-24
申请人： Humacyte, Inc.
发明人： Shannon L. M. Dahl , Laura E. Niklason , Justin T. Strader , William E. Tente , Joseph J. Lundquist
IPC分类号： A61F2/06 , C12N5/00 , A61F2/04 , B29C53/00 , B29C53/36 , A61L27/34 , B29K67/00 , B29K105/00 , B29L23/00 , B29L31/00
CPC分类号： C12N5/0068 , A61F2/04 , A61F2/06 , A61F2002/047 , A61F2002/048 , A61L27/16 , A61L27/18 , A61L27/34 , A61L27/3633 , A61L27/38 , A61L27/3895 , A61L27/54 , A61L27/58 , B29C53/005 , B29C53/36 , B29K2067/043 , B29K2105/256 , B29K2995/0056 , B29K2995/006 , B29L2023/00 , B29L2031/7532 , C12N2533/30 , C12N2533/40 , Y10T156/1038 , C08L67/04
摘要： The present invention provides constructs including a tubular biodegradable polyglycolic acid scaffold, wherein the scaffold may be coated with extracellular matrix proteins and substantially acellular. The constructs can be utilized as an arteriovenous graft, a coronary graft, a peripheral artery bypass conduit, or a urinary conduit. The present invention also provides methods of producing such constructs.
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