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公开(公告)号：US11476005B2
公开(公告)日：2022-10-18
申请号：US17465297
申请日：2021-09-02
IPC分类号： G16H50/70 , G06K9/62 , G06F16/532 , G16H30/20 , G06F16/51
摘要： Computer-implemented methods and systems are provided for curating medical images for a medical image database. An example method for curating involves operating a processor to obtain a query medical image, assign the query medical image to an initial set of related images, and generate a similarity indicator for each image of the initial set. The similarity indicator is representative of a measure of similarity between image data of that image and the initial set. The processor is operable to define an intermediate set from the initial set based on the similarity indicators; and generate a relevancy indicator for each image of the intermediate set. The relevancy indicator is representative of a measure of the relevancy between relevance of the image and the intermediate set. The processor is operable to define a curated set of images from the intermediate set based on the relevancy indicators.
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公开(公告)号：US09632301B2
公开(公告)日：2017-04-25
申请号：US14346661
申请日：2012-09-21
IPC分类号： G02B7/04 , G02B21/06 , B82Y35/00 , G02B21/00 , G01N21/64 , G02B21/16 , G02B21/34 , G02B21/36
CPC分类号： G02B21/06 , B82Y35/00 , G01N21/6456 , G02B21/002 , G02B21/16 , G02B21/34 , G02B21/367
摘要： An instrument and method for scanning a large microscope specimen uses a light source and at least one lens to focus light from the specimen onto a detector array. The specimen holder is located on a scanning stage and the detector array is dynamically tilted about a scan direction during the scan to maintain focus across the width of the scan strip as the scan proceeds. A degree of tilt varies during the scan as is required to maintain lateral focus relative to the detector array.
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3.发明申请SLIDE SCANNER WITH DYNAMIC FOCUS AND SPECIMEN TILT AND METHOD OF OPERATION 有权具有动态聚焦和样本倾斜的滑动扫描仪及其操作方法公开(公告)号：US20150054921A1
公开(公告)日：2015-02-26
申请号：US14387457
申请日：2013-03-21
CPC分类号： G02B21/365 , G02B21/006 , G02B21/0076 , G02B21/008 , G02B21/12 , G02B21/16 , G02B21/26
摘要： An instrument and method for scanning large microscope specimen on a specimen holder has a scanning optical microscope that is configured to scan the specimen in one of brightfield and fluorescence. The specimen is dynamically tillable about a scan direction during a scan to maintain focus along the length of each scan line as the scan proceeds. A three dimensional image of the specimen can be obtained wherein the specimen tilt and relative focus are maintained from a first image contour to a second image contour through a thickness of a specimen.
摘要翻译： 用于扫描样本支架上的大显微镜样本的仪器和方法具有扫描光学显微镜，其配置为以明场和荧光之一扫描样本。 在扫描过程中，样本可以围绕扫描方向动态切割，以便在扫描进行时沿着每条扫描线的长度保持对焦。 可以获得样本的三维图像，其中样本倾斜和相对聚焦通过样本的厚度从第一图像轮廓维持到第二图像轮廓。
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公开(公告)号：US20140231638A1
公开(公告)日：2014-08-21
申请号：US14346661
申请日：2012-09-21
CPC分类号： G02B21/06 , B82Y35/00 , G01N21/6456 , G02B21/002 , G02B21/16 , G02B21/34 , G02B21/367
摘要： An instrument and method for scanning a large microscope specimen uses a light source and at least one lens to focus light from the specimen onto a detector array. The specimen holder is located on a scanning stage and the detector array is dynamically tilted about a scan direction during the scan to maintain focus across the width of the scan strip as the scan proceeds. A degree of tilt varies during the scan as is required to maintain lateral focus relative to the detector array.
摘要翻译： 用于扫描大型显微镜样本的仪器和方法使用光源和至少一个透镜将来自样品的光聚焦到检测器阵列上。 样本架位于扫描台上，并且检测器阵列在扫描期间围绕扫描方向动态倾斜，以在扫描进行时将扫描条的宽度保持在扫描条的宽度上。 扫描期间的倾斜度在保持横向焦点相对于检测器阵列所需的情况下变化。
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5.发明授权公开(公告)号：US12020477B2
公开(公告)日：2024-06-25
申请号：US18110415
申请日：2023-02-16
IPC分类号： G06K9/00 , G06F16/532 , G06F16/55 , G06F16/56 , G06T7/10 , G06T9/00 , G06V10/44 , G06V10/762 , G06V10/764 , G06V10/77 , G06V10/82
CPC分类号： G06V10/82 , G06F16/532 , G06F16/55 , G06F16/56 , G06T7/10 , G06T9/002 , G06V10/44 , G06V10/762 , G06V10/764 , G06V10/77 , G06T2207/20021
摘要： Computer-implemented methods and systems are provided for generating encoded representations for multiple magnifications of one or more query images. An example method for involves operating a processor to obtain a query image and identify a set of anchor points within the query image. The processor is operable to generate a plurality of sub-images for a plurality of magnification levels for each anchor point. Each sub-image includes the anchor point and corresponds to a magnification level of the plurality of magnification levels. The processor is operable to, for each magnification level, apply an artificial neural network model to a group of sub-images having that magnification level to extract a feature vector representative of image characteristics of the query image at that magnification level; and to generate an encoded representation for multiple magnifications of the query image based on the feature vectors extracted for the plurality of magnification levels.
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公开(公告)号：US11615895B2
公开(公告)日：2023-03-28
申请号：US17901098
申请日：2022-09-01
IPC分类号： G16H50/70 , G06K9/62 , G06F16/532 , G16H30/20 , G06F16/51
摘要： Computer-implemented methods and systems are provided for curating medical images for a medical image database. An example method for curating involves operating a processor to obtain a query medical image, assign the query medical image to an initial set of related images, and generate a similarity indicator for each image of the initial set. The similarity indicator is representative of a measure of similarity between image data of that image and the initial set. The processor is operable to define an intermediate set from the initial set based on the similarity indicators; and generate a relevancy indicator for each image of the intermediate set. The relevancy indicator is representative of a measure of the relevancy between relevance of the image and the intermediate set. The processor is operable to define a curated set of images from the intermediate set based on the relevancy indicators.
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公开(公告)号：US11769582B2
公开(公告)日：2023-09-26
申请号：US16674508
申请日：2019-11-05
发明人： Hamid Reza Tizhoosh , Wafik Wagdy Moussa , Savvas Damaskinos , Patrick Myles , Alfonso Carlos Ribes
IPC分类号： G16H30/20 , G06F16/53 , G06V10/46 , G06F18/22 , G06F18/23 , G06F18/2137 , G06V10/75 , G06V10/762 , G06V10/764 , G06V10/50 , G06V20/69 , G06V10/82
CPC分类号： G16H30/20 , G06F16/53 , G06F18/2137 , G06F18/22 , G06F18/23 , G06V10/467 , G06V10/50 , G06V10/753 , G06V10/762 , G06V10/764 , G06V20/695 , G06V20/698 , G06V10/462 , G06V10/82
摘要： Computer-implemented methods and systems are provided for managing one or more images. An example method for indexing involves operating a processor to, divide an image portion of an image of the one or more images into a plurality of patches, for each patch of the image: detect one or more features of the patch; and assign the patch to at least one cluster of a plurality of clusters of the image, based on the one or more features of the patch. The processor is operable to, for each cluster of the image, select at least one patch from the cluster as at least one representative patch for the cluster; for each representative patch, generate an encoded representation based on one or more features of the representative patch; and generate an index identifier for the image based on the encoded representations of the representative patches of the image.
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公开(公告)号：US11636599B2
公开(公告)日：2023-04-25
申请号：US17944330
申请日：2022-09-14
发明人： Mahdi S. Hosseini , Konstantinos N. Plataniotis , Lyndon Chan , Jasper Hayes , Savvas Damaskinos
摘要： Various image diagnostic systems, and methods of operating thereof, are disclosed herein. Example embodiments relate to operating the image diagnostic system to identify one or more tissue types within an image patch according to a hierarchical histological taxonomy, identifying an image patch associated with normal tissue, generating a pixel-level segmented image patch for an image patch, generating an encoded image patch for an image patch of at least one tissue, searching for one or more histopathological images, and assigning an image patch to one or more pathological cases.
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公开(公告)号：US20220230316A1
公开(公告)日：2022-07-21
申请号：US17590933
申请日：2022-02-02
发明人： Mahdi S. Hosseini , Konstantinos N. Plataniotis , Lyndon Chan , Jasper Hayes , Savvas Damaskinos
摘要： Various image diagnostic systems, and methods of operating thereof, are disclosed herein. Example embodiments relate to operating the image diagnostic system to identify one or more tissue types within an image patch according to a hierarchical histological taxonomy, identifying an image patch associated with normal tissue, generating a pixel-level segmented image patch for an image patch, generating an encoded image patch for an image patch of at least one tissue, searching for one or more histopathological images, and assigning an image patch to one or more pathological cases.
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公开(公告)号：US20220068498A1
公开(公告)日：2022-03-03
申请号：US17465297
申请日：2021-09-02
IPC分类号： G16H50/70 , G06K9/62 , G06F16/51 , G16H30/20 , G06F16/532
摘要： Computer-implemented methods and systems are provided for curating medical images for a medical image database. An example method for curating involves operating a processor to obtain a query medical image, assign the query medical image to an initial set of related images, and generate a similarity indicator for each image of the initial set. The similarity indicator is representative of a measure of similarity between image data of that image and the initial set. The processor is operable to define an intermediate set from the initial set based on the similarity indicators; and generate a relevancy indicator for each image of the intermediate set. The relevancy indicator is representative of a measure of the relevancy between relevance of the image and the intermediate set. The processor is operable to define a curated set of images from the intermediate set based on the relevancy indicators.
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