公开(公告)号：US20130028898A1

公开(公告)日：2013-01-31

申请号：US13641434

申请日：2011-04-20

申请人： Hyung Kim ,  Yanping Wang

发明人： Hyung Kim ,  Yanping Wang

IPC分类号： A61K39/395 ,  A61P35/00

CPC分类号： A61K39/3955 ,  A61K31/436 ,  A61K45/06 ,  A61K2039/505 ,  C07K16/2812 ,  C07K2317/24 ,  A61K2300/00

摘要： The invention provides methods for treating a malignant neoplastic cell proliferative disorder or disease, comprising administering to a subject in need thereof an effective amount of an mTOR inhibitor and an effective amount of a CD4 lymphocyte depleting agent. Such methods find utility in the treatment of certain subsets of malignant neoplastic cell proliferative disorders or diseases, e.g. renal cell carcinoma and melanoma. The invention also provides for pharmaceutical compositions comprising a therapeutically effective amount of an mTOR inhibitor and an effective amount of a CD4 lymphocyte depleting agent in a pharmaceutically acceptable carrier.

公开(公告)号：US08906374B2

公开(公告)日：2014-12-09

申请号：US13641434

申请日：2011-04-20

申请人： Hyung Kim ,  Yanping Wang

发明人： Hyung Kim ,  Yanping Wang

IPC分类号： A61K39/395 ,  A61P37/04 ,  C07K16/28 ,  A61K45/06 ,  A61K31/436

CPC分类号： A61K39/3955 ,  A61K31/436 ,  A61K45/06 ,  A61K2039/505 ,  C07K16/2812 ,  C07K2317/24 ,  A61K2300/00

摘要： The invention provides methods for treating a malignant neoplastic cell proliferative disorder or disease, comprising administering to a subject in need thereof an effective amount of an mTOR inhibitor and an effective amount of a CD4 lymphocyte depleting agent. Such methods find utility in the treatment of certain subsets of malignant neoplastic cell proliferative disorders or diseases, e.g. renal cell carcinoma and melanoma. The invention also provides for pharmaceutical compositions comprising a therapeutically effective amount of an mTOR inhibitor and an effective amount of a CD4 lymphocyte depleting agent in a pharmaceutically acceptable carrier.

摘要翻译： 本发明提供了治疗恶性肿瘤细胞增殖性疾病或疾病的方法，包括向有需要的受试者施用有效量的mTOR抑制剂和有效量的CD4淋巴细胞消耗剂。 这些方法可用于治疗某些亚型的恶性肿瘤细胞增殖性疾病或疾病，例如， 肾细胞癌和黑色素瘤。 本发明还提供药物组合物，其包含治疗有效量的mTOR抑制剂和有效量的在药学上可接受的载体中的CD4淋巴细胞消耗剂。

公开(公告)号：US20080056493A1

公开(公告)日：2008-03-06

申请号：US11932157

申请日：2007-10-31

申请人： Byung KIM ,  Hyung Kim ,  Alexandre Stechkine

发明人： Byung KIM ,  Hyung Kim ,  Alexandre Stechkine

IPC分类号： H04N7/167

CPC分类号： G11B20/00086 ,  G06F21/10 ,  G06F2221/0704 ,  G11B7/24082 ,  G11B20/00195 ,  G11B20/0021 ,  G11B20/00246 ,  G11B20/00369

摘要： A method for managing copy protection information of a recording medium is disclosed. A data stream encrypted using copy protection information is recorded in a data area of an optical disc such as a write once optical disc or a rewritable optical disc, while the copy protection information and a drive ID are recorded together in a key locker of the optical disc. When a data stream of an optical disc is reproduced, reading and decryption of the copy protection information is selectively performed depending on whether the drive ID recorded in the key locker and a drive ID managed in an optical disc drive, into which the optical disc is inserted, are identical. This prevents contents such as broadcast programs recorded in an optical disc from being illegally duplicated.

摘要翻译： 公开了一种用于管理记录介质的复制保护信息的方法。 使用复制保护信息加密的数据流被记录在诸如一次写入光盘或可重写光盘的光盘的数据区中，而复制保护信息和驱动器ID被一起记录在光学的钥匙锁 光盘。 当再现光盘的数据流时，根据记录在密钥储物柜中的驱动器ID和在光盘驱动器中管理的驱动器ID是否选择执行复制保护信息的读取和解密 插入，是相同的。 这防止了记录在光盘中的广播节目的内容被非法复制。

公开(公告)号：US20070169279A1

公开(公告)日：2007-07-26

申请号：US11476068

申请日：2006-06-28

申请人： Jee Park ,  Hyung Kim ,  Sang Pyo ,  Jae Park ,  Sung Kim ,  Eun Bang

发明人： Jee Park ,  Hyung Kim ,  Sang Pyo ,  Jae Park ,  Sung Kim ,  Eun Bang

IPC分类号： B08B3/12 ,  D06F33/00 ,  D06F35/00 ,  D06B19/00

CPC分类号： D06F33/02 ,  D06F39/008 ,  D06F2202/04 ,  D06F2204/086 ,  D06F2220/00

摘要： A washing machine having a steam generator, which prevents the accumulation of scale in the steam generator due to the long-term use thereof, and a method for controlling the same. The washing machine includes a water supply valve for supplying water to the inside of the steam generator therethrough so as to cool the steam generator when the operating time of the steam generator exceeds a predetermined time, and a controller for controlling the operation of a heater for heating the water supplied through the water supply valve.

摘要翻译： 一种具有蒸汽发生器的洗衣机，其防止由于其长期使用而导致的蒸汽发生器中的氧化皮的积聚，以及其控制方法。 洗衣机包括供水阀，用于在蒸汽发生器的内部通过其供水，以便在蒸汽发生器的运行时间超过预定时间时冷却蒸汽发生器;以及控制器，用于控制加热器的操作 加热通过供水阀供水的水。

公开(公告)号：US20070134005A1

公开(公告)日：2007-06-14

申请号：US11635712

申请日：2006-12-07

申请人： Seung Myong ,  Hyung Kim ,  Jong Lee

发明人： Seung Myong ,  Hyung Kim ,  Jong Lee

IPC分类号： H04B10/04

CPC分类号： H04B10/5051 ,  H04B10/505 ,  H04B10/508

摘要： Provided are an apparatus and a method for generating a return-to-zero (RZ) signal, including: a first modulator receiving a first signal having a predetermined frequency to modulate, compensate for and output a first laser beam; a second modulator receiving a second signal complementary to the first signal to modulate, compensate for, and output a second laser beam; a mixer mixing signals output from the first and second modulators to output a third signal; and a third modulator modulating the third signal into an RZ signal and outputting the RZ signal.

摘要翻译： 提供了一种用于产生归零（RZ）信号的装置和方法，包括：第一调制器，接收具有预定频率的第一信号以调制，补偿和输出第一激光束; 接收与所述第一信号互补的第二信号以调制，补偿和输出第二激光束的第二调制器; 混合从第一和第二调制器输出的信号以输出第三信号; 以及将第三信号调制成RZ信号并输出​​RZ信号的第三调制器。

公开(公告)号：US20070101773A1

公开(公告)日：2007-05-10

申请号：US11500513

申请日：2006-08-08

申请人： Jae Park ,  Hyung Kim ,  Sang Pyo ,  Sun Park ,  Sung Kang

发明人： Jae Park ,  Hyung Kim ,  Sang Pyo ,  Sun Park ,  Sung Kang

IPC分类号： D06F37/00 ,  B08B3/12 ,  D06F25/00

CPC分类号： D06F39/008 ,  D06F39/04

摘要： A drum washing machine, in which scale deposited in a steam generating device installed for improving sterilizing and washing capacities is efficiently eliminated. The drum washing machine includes a housing; a tub for containing washing water; a drum rotatably installed in the tub; and a steam generating device installed in the housing for supplying steam for sterilizing laundry to the drum, wherein a scale eliminating unit is installed in a water supply channel of the steam generating device, and includes at least one protrusion formed on the inner circumferential surface of the water supply channel or a water supply valve and a pulsation circuit for controlling the flow rate and amount of the water. The scale eliminating unit forms turbulence in the steam generating device or supplies water having varied flow rate and amount to the steam generating device, thereby efficiently eliminating scale deposited in the steam generating device.

摘要翻译： 有效地消除了沉积在安装用于提高消毒和洗涤能力的蒸汽发生装置中的水垢的滚筒洗衣机。 滚筒洗衣机包括壳体; 一个含洗涤水的洗手盆; 可旋转地安装在桶中的滚筒; 以及蒸汽发生装置，其安装在所述壳体中，用于向所述滚筒提供用于将衣物消毒的蒸汽，其中，所述除垢单元安装在所述蒸汽发生装置的供水通道中，并且包括形成在所述蒸汽发生装置的内周面上的至少一个突起， 供水通道或供水阀和用于控制水的流量和量的脉动电路。 除垢单元在蒸汽发生装置中形成湍流，或者向蒸汽发生装置供给具有变化的流量和量的水，从而有效地消除蒸汽发生装置中沉积的垢。

公开(公告)号：US20070098487A1

公开(公告)日：2007-05-03

申请号：US11264611

申请日：2005-10-31

申请人： Hyung Kim

发明人： Hyung Kim

IPC分类号： F16B7/10

CPC分类号： B25G3/18 ,  B25G1/04 ,  F16B7/00 ,  Y10T403/32467

摘要： A pole adaptor for connecting and disconnecting a multi-task pole with an attachment tool provides a secure connection and preserves the useful life of the multi-task pole. The adaptor embodies an elongated cylindrical housing having a first open end with two clip holes, a mid-section, and a second open end having four tab holes. The first open end forms a receptacle for the multi-task pole and an alignment with the clip holes for securely attaching the pole adaptor. The second open end forms a receptacle for the attachment tool handle and allowing the handle tabs to connect with two tab holes therein. Four tab holes are provided at the second open end for continued use of the adaptor if two tab wholes wear out.

摘要翻译： 用于使用附件工具连接和断开多任务杆的极适配器提供了一个安全的连接，并保留了多任务杆的使用寿命。 适配器具有细长的圆柱形壳体，其具有带有两个夹孔的第一开口端，中间部分和具有四个突出孔的第二开口端。 第一开口端形成用于多任务极的插座和与夹子孔对准，用于牢固地连接极适配器。 第二开口端形成用于附接工具手柄的插座，并且允许手柄接片与其中的两个接头孔连接。 在第二开口端设有四个接头孔，以便如果两个接头的整体磨损，则继续使用适配器。

公开(公告)号：US20070019491A1

公开(公告)日：2007-01-25

申请号：US11270650

申请日：2005-11-10

申请人： Young Jang ,  Jin So ,  Hyung Kim

发明人： Young Jang ,  Jin So ,  Hyung Kim

IPC分类号： G11C7/00

CPC分类号： G11C11/406 ,  G11C11/408 ,  G11C11/4087

摘要： A refresh control circuit and semiconductor devices that may include an address counter for generating a counting address, a repetition address selector for generating a repetition address, a repetition refresh controller for generating a refresh repetition signal based on the counting address and repetition address, and a row decoder for selecting a row of a memory bank based on the counting address and the refresh repetition signal. A method for performing a refresh operation on a semiconductor device that may include receiving a refresh trigger, generating a counting address, generating a repetition address corresponding to a row having a degraded memory cell, providing a refresh repetition signal based on a comparison of the counting address and repetition address, and selecting a row to be refreshed based on one or more of the counting address, repetition address, and the refresh repetition address.

摘要翻译： 刷新控制电路和半导体器件，其可以包括用于产生计数地址的地址计数器，用于产生重复地址的重复地址选择器，用于基于计数地址和重复地址产生刷新重复信号的重复刷新控制器，以及 行解码器，用于基于计数地址和刷新重复信号来选择存储体组的行。 一种用于在半导体器件上执行刷新操作的方法，所述方法包括：接收刷新触发，产生计数地址，产生与具有劣化存储单元的行对应的重复地址，基于计数的比较提供刷新重复信号 地址和重复地址，并且基于计数地址，重复地址和刷新重复地址中的一个或多个来选择要刷新的行。

公开(公告)号：US20060287405A1

公开(公告)日：2006-12-21

申请号：US11450580

申请日：2006-06-10

申请人： Young Baek ,  Won Cho ,  Byoung Cho ,  Jung Suh ,  Dong Kim ,  Hyung Kim ,  Seung Lee ,  Woo Ju

发明人： Young Baek ,  Won Cho ,  Byoung Cho ,  Jung Suh ,  Dong Kim ,  Hyung Kim ,  Seung Lee ,  Woo Ju

IPC分类号： C07C27/06

CPC分类号： C07C41/09 ,  C07C41/01 ,  C07C43/043

摘要： Disclosed herein is a process for the preparation of dimethylether from hydrocarbons, including tri-reforming a feedstock mixture comprised of hydrocarbons, carbon dioxide and water vapor in the presence of a tri-reforming catalyst, to prepare a syngas, which then undergoes gas-phase direct synthesis into dimethylether in one step in the presence of a hybrid catalyst. According to the process of this invention, three main processes among typical syngas preparation processes are simultaneously performed, and then, the syngas thus obtained is prepared into dimethylether through a direct reaction in one step, thereby decreasing the apparatus cost and operation cost. In addition, all of the carbon dioxide separated and recovered from the unreacted material and by-products may be reused as reaction material, thus decreasing the generation of carbon dioxide and reducing the material cost.

摘要翻译： 本文公开了一种从烃制备二甲醚的方法，包括在三重转化催化剂的存在下，由烃，二氧化碳和水蒸气组成的原料混合物进行三重重整，以制备合成气，然后合成气经历气相 在混合催化剂存在下，在一个步骤中直接合成二甲醚。 根据本发明的方法，同时进行典型的合成气制备过程中的三个主要过程，然后通过一步直接反应将由此获得的合成气制备成二甲醚，从而降低设备成本和操作成本。 此外，从未反应的物质和副产物中分离回收的二氧化碳全部可以作为反应物质再利用，从而减少二氧化碳的产生并降低材料成本。

公开(公告)号：US20060252053A1

公开(公告)日：2006-11-09

申请号：US11259640

申请日：2005-10-25

申请人： Alex Stegh ,  Hyung Kim ,  Ronald Depinho ,  Lynda Chin

发明人： Alex Stegh ,  Hyung Kim ,  Ronald Depinho ,  Lynda Chin

IPC分类号： C12Q1/68 ,  G01N33/53

CPC分类号： G01N33/5748 ,  A61K48/00 ,  C07K14/4747 ,  C07K14/82 ,  C12Q1/37 ,  C12Q1/6886 ,  C12Q2600/136 ,  G01N2333/96466

摘要： The invention provides methods and materials related to Bcl2L12 polypeptides and the biological activities of Bcl2L12 polypeptides. For example, the invention provides methods and materials related to identifying activators and inhibitors of Bcl2L12 polypeptide activities such as the ability to block apoptosis and promote cell growth and transformation. The invention also provides methods and materials for treating mammals having cancer.