公开(公告)号：US20240198310A1

公开(公告)日：2024-06-20

申请号：US18540851

申请日：2023-12-14

Applicant: ILLUMINA, INC.

Inventor： Emily Parker ,  Bryan Crane ,  Peter Thomas ,  Megan Blanchard ,  James Osmus ,  Bradley Drews ,  Richard Lemoine ,  Gregory Holst

IPC: B01J19/00

CPC classification number: B01J19/0046 ,  B01J2219/00351 ,  B01J2219/005

Abstract: Library preparation systems and methods are disclosed. In an implementation, a modular bay for preparing a library of samples for sequencing, the modular bay comprising a contact dispenser and a working area comprising a working plate receptacle adapted to receive a working plate, a thermocycler, a magnet, and a drawer. The drawer comprising a consumables area adapted to receive a sample plate adapted to contain a sample, and a plurality of consumables for interacting with the sample in the working plate. The contact dispenser is linearly movable in a longitudinal direction between the consumables area and the working area, such that the contact dispenser is configured to (i) move the sample from the sample plate in the consumables area to the working plate in the working area, and (ii) move the plurality of consumables between the consumables area and the working plate in the working area.

公开(公告)号：US12000854B2

公开(公告)日：2024-06-04

申请号：US17831222

申请日：2022-06-02

Applicant: Illumina, Inc.

Inventor： Wesley A. Cox-Muranami ,  James Osmus ,  Paul Crivelli ,  Bradley Kent Drews

IPC: G01N35/10

CPC classification number: G01N35/1097

Abstract: An apparatus includes a fluidic circuit, a bypass fluidic circuit, a first set of fluid wells, a second set of fluid wells, a first valve, and a second valve. The first valve operatively associated with the first set of fluid wells such that the first selectively fluidly connects any one of the first set of fluid wells to a first valve outlet. The second valve operatively associated with the fluidic circuit, the bypass fluidic circuit, the first valve outlet, and the second set of fluid wells such that the second valve selectively fluidly connects any one of the second set of fluid wells and the first valve outlet to the fluidic circuit or the first valve outlet to the bypass fluidic circuit.

公开(公告)号：US11892080B2

公开(公告)日：2024-02-06

申请号：US17590520

申请日：2022-02-01

Applicant: ILLUMINA, INC.

Inventor： Ashish Kumar ,  James Osmus ,  David Kaplan ,  Richard Lemoine

IPC: H01M50/183 ,  F16J15/10 ,  F28F3/10

CPC classification number: F16J15/104 ,  H01M50/183 ,  F28F3/10

Abstract: Gasket assemblies and related system and methods. An apparatus includes a system, a flow cell, and a plurality of gasket assemblies. The system includes a flow cell interface and the flow cell has one or more channels. Each channel has a first channel opening and a second channel opening. The first channel openings are positioned at a first end of the flow cell and the second channel openings are positioned at a second end of the flow cell. A gasket assembly coupled at each second channel opening. Each gasket assembly includes an adhesive stack and a gasket. The adhesive stack includes a first side bonded to the gasket and a second side bonded to the flow cell. The flow cell interface is engagable with the corresponding gaskets to establish a fluidic coupling between system and the flow cell.

公开(公告)号：USD1012313S1

公开(公告)日：2024-01-23

申请号：US29864480

申请日：2022-05-31

Applicant: Illumina, Inc.

Designer： Jay Taylor ,  James Osmus ,  Philip Paik ,  Jack Godfrey Wood ,  Carlos Dominguez

Abstract: FIG. 1 is a top, rear perspective view of a flow cell cartridge comprising our new design;
FIG. 2 is a top plan view thereof;
FIG. 3 is a bottom plan view thereof;
FIG. 4 is a left side elevational view thereof;
FIG. 5 is a right side elevational view thereof;
FIG. 6 is a front elevational view thereof; and,
FIG. 7 is an enlarged rear elevational view thereof.
The evenly broken lines shown in the drawings illustrate portions of the flow cell cartridge that form no part of the claimed design.

公开(公告)号：US20220243818A1

公开(公告)日：2022-08-04

申请号：US17590520

申请日：2022-02-01

Applicant: Illumina, Inc.

Inventor： Ashish Kumar ,  James Osmus ,  David Kaplan ,  Richard Lemoine

IPC: F16J15/10

Abstract: Gasket assemblies and related system and methods. An apparatus includes a system, a flow cell, and a plurality of gasket assemblies. The system includes a flow cell interface and the flow cell has one or more channels. Each channel has a first channel opening and a second channel opening. The first channel openings are positioned at a first end of the flow cell and the second channel openings are positioned at a second end of the flow cell. A gasket assembly coupled at each second channel opening. Each gasket assembly includes an adhesive stack and a gasket. The adhesive stack includes a first side bonded to the gasket and a second side bonded to the flow cell. The flow cell interface is engagable with the corresponding gaskets to establish a fluidic coupling between system and the flow cell.

公开(公告)号：USD952892S1

公开(公告)日：2022-05-24

申请号：US29714661

申请日：2019-11-25

Applicant: Illumina, Inc.

Designer： James Osmus ,  Erik Allegoren ,  James Blake ,  Philip Paik ,  Jay Taylor ,  Jack Godfrey-Wood ,  Carlos Dominguez

公开(公告)号：USD999425S1

公开(公告)日：2023-09-19

申请号：US29714669

申请日：2019-11-25

Applicant: Illumina, Inc.

Designer： Jay Taylor ,  James Osmus ,  Philip Paik ,  Jack Godfrey Wood ,  Max Pollock

Abstract: FIG. 1 is a perspective view of a cartridge cover showing our new design;
FIG. 2 is a top plan view of the design of FIG. 1;
FIG. 3 is a bottom plan view of the design of FIG. 1;
FIG. 4 is a left side elevational view of the design of FIG. 1;
FIG. 5 is a right side elevational view of the design of FIG. 1;
FIG. 6 is a front elevational view of the design of FIG. 1;
FIG. 7 is a rear elevational view of the design of FIG. 1;
FIG. 8 is a cross-sectional view taken along line 8-8 in FIG. 2;
FIG. 9 is a perspective view of an alternate embodiment of the design shown in FIG. 1;
FIG. 10 is a top plan view of the design of FIG. 9;
FIG. 11 is a bottom plan view of the design of FIG. 9;
FIG. 12 is a left side elevational view of the design of FIG. 9;
FIG. 13 is a right side elevational view of the design of FIG. 9;
FIG. 14 is a front elevational view of the design of FIG. 9;
FIG. 15 is a rear elevational view of the design of FIG. 9; and,
FIG. 16 is a cross-sectional view taken along line 16-16 in FIG. 10.
The broken lines shown in the drawings illustrate portions of the cartridge cover that form no part of the claimed design.

公开(公告)号：US20220291250A1

公开(公告)日：2022-09-15

申请号：US17831222

申请日：2022-06-02

Applicant: Illumina, Inc.

Inventor： Wesley A. Cox-Muranami ,  James Osmus ,  Paul Crivelli ,  Bradley Kent Drews

IPC: G01N35/10

Abstract: An apparatus includes a fluidic circuit, a bypass fluidic circuit, a first set of fluid wells, a second set of fluid wells, a first valve, and a second valve. The first valve operatively associated with the first set of fluid wells such that the first selectively fluidly connects any one of the first set of fluid wells to a first valve outlet. The second valve operatively associated with the fluidic circuit, the bypass fluidic circuit, the first valve outlet, and the second set of fluid wells such that the second valve selectively fluidly connects any one of the second set of fluid wells and the first valve outlet to the fluidic circuit or the first valve outlet to the bypass fluidic circuit.

公开(公告)号：USD942034S1

公开(公告)日：2022-01-25

申请号：US29745314

申请日：2020-08-05

Applicant: Illumina, Inc.

Designer： James Osmus ,  Erik Allegoren ,  James Blake ,  Philip Paik ,  Jay Taylor ,  Jack Godfrey Wood

公开(公告)号：US10576471B2

公开(公告)日：2020-03-03

申请号：US15559321

申请日：2016-03-18

Applicant: ILLUMINA, Inc.

Inventor： James Osmus ,  Richard L. Lemoine ,  Jian Gong ,  Sz-Chin Steven Lin

IPC: B01L3/00

Abstract: Disclosed herein are devices, systems and methods for conducting a reaction using electrowetting in a vertical or substantially vertical position. Some embodiments disclosed herein provide fluidic cartridges for use in a substantially vertical position comprising: (a) a front substrate; (b) a back substrate; (c) a droplet operations gap formed between the front substrate and the back substrate; and (d) a plurality of electrodes on the front substrate or the back substrate, wherein the plurality of electrodes are configured to transport a droplet along a substantially vertical plane defined by the front substrate and the back substrate.