MOLECULAR ANALYSIS DEVICE
    2.
    发明申请
    MOLECULAR ANALYSIS DEVICE 有权
    分子分析装置

    公开(公告)号:US20140185042A1

    公开(公告)日:2014-07-03

    申请号:US14143805

    申请日:2013-12-30

    Abstract: In the present invention, a molecular analysis device comprises a substrate, and a waveguide with a planar integrating element and filter or reflector element adjacent thereto is disposed on the substrate. The waveguide comprises a coupling means configured for coupling a predetermined frequency range of laser radiation into the waveguide. At least one metallic nanostructure is disposed on or adjacent to the planar integrating element, at least one metallic nanostructure is configured such that the field intensity and the gradient of the laser radiation, that is coupled into the waveguide, are enhanced over a sufficiently large volume around the nanostructure to simultaneously cause plasmonic based optical trapping of analyte(s) in a medium, and plasmonic based excitation of the particles to produce Raman scattered radiation. A Raman scattered radiation collection means is disposed on the substrate for collecting said Raman scattered radiation produced by the particles.

    Abstract translation: 在本发明中,分子分析装置包括衬底,并且具有平面积分元件的波导和与其相邻的过滤器或反射器元件设置在衬底上。 波导包括被配置为将激光辐射的预定频率范围耦合到波导中的耦合装置。 至少一个金属纳米结构设置在平面积分元件上或附近,至少一个金属纳米结构被配置为使得耦合到波导中的激光辐射的场强和梯度在足够大的体积上被增强 围绕纳米结构同时引起介质中分析物的等离子体光学捕获,以及等离子体激发的颗粒以产生拉曼散射辐射。 拉曼散射辐射收集装置设置在基板上用于收集由颗粒产生的所述拉曼散射辐射。

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