专利检索 ap:("ImmunoGen, Inc.") AND inv:"Olga Ab" 第 1 页

1.

发明授权
Diagnostic assays and kits for detection of folate receptor 1 有权

公开(公告)号：US10180432B2

公开(公告)日：2019-01-15

申请号：US15620117

申请日：2017-06-12

申请人： ImmunoGen, Inc.

发明人： Christina N. Carrigan , Olga Ab , Daniel Tavares , Beni B. Wolf

IPC分类号： G01N33/574 , A61K47/68 , C07K16/30 , C07K16/28 , G01N33/566

摘要： The invention generally relates to antibodies that bind to human folate receptor 1 and diagnostic assays for folate receptor 1-based therapies. Methods of using the antibodies to monitor therapy are further provided.

2.

发明授权
Diagnostic assays and kits for detection of folate receptor 1 有权

公开(公告)号：US09702881B2

公开(公告)日：2017-07-11

申请号：US14921596

申请日：2015-10-23

申请人： ImmunoGen, Inc.

发明人： Christina N. Carrigan , Olga Ab , Daniel Tavares , Beni B. Wolf , Nathan E. Testa

IPC分类号： G01N33/574 , G01N33/566 , C07K16/28 , C07K16/30 , A61K47/48

CPC分类号： G01N33/57492 , A61K47/6849 , C07K16/28 , C07K16/30 , C07K16/3015 , C07K16/3023 , C07K16/303 , C07K16/3069 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/76 , C07K2317/92 , G01N33/566 , G01N2333/705

摘要： The invention generally relates to antibodies that bind to human folate receptor 1 and diagnostic assays for folate receptor 1-based therapies. Methods of using the antibodies to monitor therapy are further provided.

3.

发明申请
Anti-FOLR1 Immunoconjugate Dosing Regimens 审中-公开
标题翻译：抗FOLR1免疫接种给药方案

公开(公告)号：US20140363451A1

公开(公告)日：2014-12-11

申请号：US14276917

申请日：2014-05-13

申请人： ImmunoGen, Inc.

发明人： Kelli RUNNING , Robert A. Mastico , James J. O'Leary , Olga Ab , Beni Wolf

IPC分类号： A61K47/48 , C07K16/28 , A61K39/395 , A61K31/573

CPC分类号： A61K9/0019 , A61K31/5365 , A61K31/573 , A61K45/06 , A61K47/6803 , A61K47/6849 , A61K47/6857 , A61K47/6869 , A61K2039/505 , A61K2039/545 , C07K16/28 , C07K16/2857 , C07K2317/94 , A61K2300/00

摘要： Methods of administering immunoconjugates that bind to FOLR1 are provided. The methods comprise administering an anti-FOLR1 immunoconjugate to a person in need thereof, for example, a cancer patient, at a therapeutically effective dosing regimen that results in minimal adverse effects.

摘要翻译： 提供了与FOLR1结合的免疫缀合物的给药方法。所述方法包括以有效的给药方案向有需要的人（例如癌症患者）施用抗FOLR1免疫偶联物，其导致最小的不良反应。

4.

发明授权
Method for identifying an ovarian cancer in a subject likely to respond to anti-folate receptor 1 (FOLR1) antibody 有权

公开(公告)号：US11198736B2

公开(公告)日：2021-12-14

申请号：US16707940

申请日：2019-12-09

申请人： ImmunoGen, Inc.

发明人： Olga Ab , Daniel Tavares , Juliantro Setiady , Sharron Ladd , Christina N. Carrigan , Lingyun Rui

IPC分类号： C07K16/30 , C07K16/28 , A61K47/68 , A61K39/00 , G01N33/574 , G01N33/547

摘要： The invention generally relates to antibodies that bind to human folate receptor and diagnostic assays for folate receptor 1-based therapies. Methods of using the antibodies to monitor therapy are further provided.

5.

发明授权
Methods of treating cancer in a patient by administering anti-folate-receptor-1 (FOLR1) antibodies 有权

公开(公告)号：US10017578B2

公开(公告)日：2018-07-10

申请号：US15473008

申请日：2017-03-29

申请人： ImmunoGen, Inc.

发明人： Olga Ab , Daniel Tavares , Julianto Setiady , Sharron Ladd , Christina N. Carrigan , Lingyun Rui

IPC分类号： C07K16/30 , G01N33/574 , C07K16/28 , A61K47/48 , A61K39/00

CPC分类号： C07K16/30 , A61K47/6803 , A61K47/6849 , A61K2039/505 , C07K16/28 , C07K2317/24 , C07K2317/33 , C07K2317/565 , C07K2317/92 , G01N33/57411 , G01N33/57415 , G01N33/57449 , G01N33/57492 , G01N2800/52

摘要： The invention generally relates to antibodies that bind to human folate receptor and diagnostic assays for folate receptor 1-based therapies. Methods of using the antibodies to monitor therapy are further provided.

6.

发明授权
Folate receptor 1 antibodies and immunoconjugates and uses thereof 有权

公开(公告)号：US09598490B2

公开(公告)日：2017-03-21

申请号：US14970433

申请日：2015-12-15

申请人： ImmunoGen, Inc.

发明人： Olga Ab , Daniel Tavares , Lingyun Rui , Gillian Payne , Viktor S. Goldmakher

IPC分类号： C07K16/00 , C12P21/08 , C07K16/28 , A61K47/48 , A61K39/395 , A61K45/06 , C07K16/30 , A61K31/5365 , A61K39/00

CPC分类号： C07K16/28 , A61K31/5365 , A61K31/537 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K47/545 , A61K47/6803 , A61K47/6849 , A61K47/6851 , A61K47/6889 , A61K2039/505 , C07H21/00 , C07K16/30 , C07K16/3069 , C07K2317/14 , C07K2317/24 , C07K2317/31 , C07K2317/52 , C07K2317/524 , C07K2317/526 , C07K2317/53 , C07K2317/54 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/622 , C07K2317/624 , C07K2317/626 , C07K2317/71 , C07K2317/73 , C07K2317/732 , C07K2317/92 , C07K2317/94 , C12N5/16 , C12N15/62 , C12N15/63 , C12N15/70 , C12N15/79 , C12N2800/00

摘要： Novel anti-cancer agents, including, but not limited to, antibodies and immunoconjugates, that bind to human folate receptor 1 are provided. Methods of using the agents, antibodies, or immunoconjugates, such as methods of inhibiting tumor growth are further provided.

7.

发明授权
Folate receptor 1 antibodies and immunoconjugates and uses thereof 有权
标题翻译：叶酸受体1抗体和免疫缀合物及其用途

公开(公告)号：US09133275B2

公开(公告)日：2015-09-15

申请号：US13800835

申请日：2013-03-13

申请人： ImmunoGen, Inc.

发明人： Olga Ab , Daniel Tavares , Lingyun Rui , Gillian Payne , Viktor S. Goldmakher

IPC分类号： A61K39/395 , A61K39/00 , C07K16/30 , A61K47/48 , C07K16/28 , A61K45/06

CPC分类号： C07K16/28 , A61K31/5365 , A61K31/537 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K47/545 , A61K47/6803 , A61K47/6849 , A61K47/6851 , A61K47/6889 , A61K2039/505 , C07H21/00 , C07K16/30 , C07K16/3069 , C07K2317/14 , C07K2317/24 , C07K2317/31 , C07K2317/52 , C07K2317/524 , C07K2317/526 , C07K2317/53 , C07K2317/54 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/622 , C07K2317/624 , C07K2317/626 , C07K2317/71 , C07K2317/73 , C07K2317/732 , C07K2317/92 , C07K2317/94 , C12N5/16 , C12N15/62 , C12N15/63 , C12N15/70 , C12N15/79 , C12N2800/00

摘要： Novel anti-cancer agents, including, but not limited to, antibodies and immunoconjugates, that bind to human folate receptor 1 are provided. Methods of using the agents, antibodies, or immunoconjugates, such as methods of inhibiting tumor growth are further provided.

摘要翻译： 提供了与人叶酸受体1结合的新型抗癌剂，包括但不限于抗体和免疫缀合物。进一步提供使用试剂，抗体或免疫缀合物的方法，例如抑制肿瘤生长的方法。

8.

发明授权
Folate receptor 1 antibodies and immunoconjugates and uses thereof 有权

公开(公告)号：US10752683B2

公开(公告)日：2020-08-25

申请号：US16384031

申请日：2019-04-15

申请人： ImmunoGen, Inc.

发明人： Olga Ab , Daniel Tavares , Lingyun Rui , Gillian Payne , Viktor S. Goldmakher

IPC分类号： A61K39/395 , C07K16/28 , C07K16/30 , A61K47/68 , A61K47/54 , A61K45/06 , A61K31/5365 , A61K31/537 , C12N15/63 , C12N5/16 , C07H21/00 , C12N15/62 , C12N15/70 , C12N15/79 , A61K39/00

摘要： Novel anti-cancer agents, including, but not limited to, antibodies and immunoconjugates, that bind to human folate receptor 1 are provided. Methods of using the agents, antibodies, or immunoconjugates, such as methods of inhibiting tumor growth are further provided.

9.

发明授权
Folate receptor 1 antibodies and immunoconjugates and uses thereof 有权

公开(公告)号：US10301385B2

公开(公告)日：2019-05-28

申请号：US15583281

申请日：2017-05-01

申请人： ImmunoGen, Inc.

发明人： Olga Ab , Daniel Tavares , Lingyun Rui , Gillian Payne , Viktor S. Goldmakher

IPC分类号： C07K16/28 , C07K16/30 , A61K39/395 , A61K51/10 , C12N15/79 , A61K45/06 , A61K31/5365 , A61K47/68 , A61K47/54 , A61K31/537 , C12N15/63 , C12N5/16 , C07H21/00 , C12N15/62 , C12N15/70 , A61K39/00

摘要： Novel anti-cancer agents, including, but not limited to, antibodies and immunoconjugates, that bind to human folate receptor 1 are provided. Methods of using the agents, antibodies, or immunoconjugates, such as methods of inhibiting tumor growth are further provided.