公开(公告)号：US20020146770A1

公开(公告)日：2002-10-10

申请号：US10051986

申请日：2002-01-15

申请人： Incyte Pharmaceuticals, Inc.

发明人： Jennifer L. Hillman ,  Y. Tom Tang ,  Preeti Lal ,  Karl J. Guegler ,  Neil C. Corley ,  Chandra Patterson ,  Sajeev Batra ,  Mariah R. Baughn

IPC分类号： C12Q001/68 ,  G01N033/53 ,  C07H021/04 ,  C12N009/10 ,  C12P021/02 ,  C12N005/06

CPC分类号： C07K14/4722 ,  A61K38/00

摘要： The invention provides seven human Ras proteins (RASP) and polynucleotides which identify and encode RASP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of RASP.

摘要翻译： 本发明提供了七种人类Ras蛋白（RASP）和识别和编码RASP的多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供了用于诊断，治疗或预防与RASP表达相关的疾病的方法。

公开(公告)号：US20020102708A1

公开(公告)日：2002-08-01

申请号：US09925122

申请日：2001-08-08

申请人： Incyte Pharmaceuticals, Inc.

发明人： Olga Bandman ,  Karl J. Guegler ,  Preeti Lal

IPC分类号： C12N009/64 ,  A01K067/00 ,  C07H021/04 ,  C12P021/02 ,  C12N005/06

CPC分类号： C07K14/47 ,  A61K38/00

摘要： The invention provides a human SH3-containing protein (HS3C) and polynucleotides which identify and encode HS3C. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HS3C.

摘要翻译： 本发明提供含有人SH3的蛋白质（HS3C）和识别和编码HS3C的多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供了治疗或预防与HS3C表达相关的病症的方法。

公开(公告)号：US20020086406A1

公开(公告)日：2002-07-04

申请号：US09930026

申请日：2001-08-14

申请人： Incyte Pharmaceuticals, Inc.

发明人： Preeti Lal ,  Jennifer L. Hillman ,  Karl J. Guegler ,  Neil C. Corley ,  Mariah Baughn ,  Yalda Azimzai

IPC分类号： C12N009/64 ,  C12Q001/68 ,  A01K067/00 ,  C12N005/06 ,  C12N001/21 ,  C12P021/02

CPC分类号： C12N9/93

摘要： The invention provides human ubiquitin-conjugating enzyme homologs (UCEH) and polynucleotides which identify and encode UCEH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of UCEH.

摘要翻译： 本发明提供了人泛素缀合酶同源物（UCEH）和识别和编码UCEH的多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供用于诊断，治疗或预防与UCEH表达相关的障碍的方法。

公开(公告)号：US20020086394A1

公开(公告)日：2002-07-04

申请号：US09969959

申请日：2001-10-01

申请人： Incyte Pharmaceuticals, Inc.

发明人： Olga Bandman ,  Y. Tom Tang ,  Preeti Lal ,  Neil C. Corley ,  Karl J. Guegler ,  Chandra Patterson

IPC分类号： C12N009/16 ,  A01K067/00 ,  C07H021/04 ,  C12P021/02 ,  C12N005/06 ,  C12N001/21 ,  C12N009/14

CPC分类号： C12N9/14 ,  A61K38/00

摘要： The invention provides human vacuolar proton ATPase subunits (VATPS) and polynucleotides which identify and encode VATPS. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of VATPS.

摘要翻译： 本发明提供了鉴定和编码VATPS的人液泡质子ATP酶亚基（VATPS）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供用于诊断，治疗或预防与VATPS表达相关的疾病的方法。

公开(公告)号：US20020068341A1

公开(公告)日：2002-06-06

申请号：US09764762

申请日：2001-01-16

申请人： Incyte Pharmaceuticals, Inc.

发明人： Jennifer L. Hillman ,  Preeti Lal

IPC分类号： C12N009/00 ,  C07H021/04 ,  C12P021/02 ,  C12N005/06

CPC分类号： C12N9/6424 ,  A61K38/00 ,  C12N9/6445

摘要： The present invention provides a human tumor suppressor (HKALL) and polynucleotides which identify and encode HKALL. The invention also provides expression vectors and host cells, agonists, antibodies, or antagonists. The invention provides methods for treating diseases associated with expression of HKALL.

公开(公告)号：US20020103339A1

公开(公告)日：2002-08-01

申请号：US09947316

申请日：2001-09-05

申请人： Incyte pharmaceuticals, Inc.

发明人： Jennifer L. Hillman ,  Preeti Lal ,  Neil C. Corley ,  Karl J. Guegler ,  Chandra Patterson ,  Mariah R. Baughn ,  Susan K. Sather ,  Purvi Shah

IPC分类号： C07K014/435 ,  A01K067/00 ,  C07H021/04 ,  C12P021/02 ,  C12N001/21 ,  C12N005/06

CPC分类号： C07K14/523 ,  A61K38/00 ,  C07K14/4702 ,  C07K14/7158

摘要： The invention provides human ISRE-binding protein (HIBP) and polynucleotides which identify and encode HIBP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of HIBP.

摘要翻译： 本发明提供了人类ISRE结合蛋白（HIBP）和鉴定和编码HIBP的多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供用于诊断，治疗或预防与HIBP表达相关的障碍的方法。

公开(公告)号：US20020098543A1

公开(公告)日：2002-07-25

申请号：US09866356

申请日：2001-05-24

申请人： Incyte Pharmaceuticals, Inc.

发明人： Olga Bandman ,  Karl J. Guegler ,  Preeti Lal ,  Neil C. Corley

IPC分类号： C12Q001/68 ,  C07H021/04 ,  C12P021/02 ,  C12N005/06

CPC分类号： C07K14/4748

摘要： The invention provides a human prostate associated Ets protein (PRAEP) and polynucleotides which identify and encode PRAEP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of PRAEP.

摘要翻译： 本发明提供了人前列腺相关的Ets蛋白（PRAEP）和识别和编码PRAEP的多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供了治疗或预防与PRAEP表达相关的疾病的方法。

公开(公告)号：US20020076762A1

公开(公告)日：2002-06-20

申请号：US09938803

申请日：2001-08-24

申请人： Incyte Pharmaceuticals, Inc.

发明人： Henry Yue ,  Y. Tom Tang ,  Preeti Lal ,  Roopa Reddy ,  Mariah R. Baughn ,  Junming Yang ,  Yalda Azimzai

IPC分类号： C12P021/02 ,  C07K014/435 ,  C12N001/21 ,  C12N005/06 ,  C07H021/04 ,  C12N009/00

CPC分类号： C12Q1/6886 ,  A01K2217/05 ,  A61K38/00 ,  C07H21/04 ,  C07K14/47 ,  C12Q2600/106 ,  C12Q2600/136

摘要： The invention provides full-length expressed genetic markers (FLEXGEM) and polynucleotides which identify and encode FLEXGEM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of FLEXGEM.

摘要翻译： 本发明提供了全长表达的遗传标记（FLEXGEM）和识别和编码FLEXGEM的多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供了用于诊断，治疗或预防与FLEXGEM表达相关的障碍的方法。

公开(公告)号：US20020058264A1

公开(公告)日：2002-05-16

申请号：US09840787

申请日：2001-09-26

申请人： Incyte Pharmaceuticals, Inc

发明人： Preeti Lal ,  Jennifer L. Hillman ,  Olga Bandman ,  Purvi Shah ,  Janice Au-Young ,  Henry Yue ,  Karl J. Guegler ,  Neil C. Corley

IPC分类号： C12Q001/68 ,  C07H021/04 ,  C12N009/00 ,  C12N005/06 ,  C12P021/02

CPC分类号： C12N9/93 ,  A61K38/00 ,  C07K14/4702 ,  Y10T436/143333

摘要： The invention provides human regulatory molecules and the polynucleotides which identify and encode them. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention further provides methods for diagnosing and treating disorders associated with expression of human regulatory molecules.

摘要翻译： 本发明提供了人体调节分子和鉴定和编码它们的多核苷酸。 本发明还提供表达载体，宿主细胞，激动剂，抗体和拮抗剂。 本发明还提供了用于诊断和治疗与人体调节分子的表达相关的疾病的方法。

公开(公告)号：US20020009778A1

公开(公告)日：2002-01-24

申请号：US09850887

申请日：2001-05-07

申请人： Incyte Pharmaceuticals, Inc.

发明人： Preeti Lal ,  Neil C. Corley ,  Gina Gorgone

IPC分类号： C12Q001/68 ,  C07H021/04 ,  C12N009/00 ,  C12P021/02 ,  C12N005/06 ,  C12N001/21

CPC分类号： C07K14/705 ,  A61K38/00 ,  G01N33/78 ,  G01N2500/04

摘要： The invention provides a human thyroid and pituitary membrane protein (TPMP) and polynucleotides which identify and encode TPMP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of TPMP.

摘要翻译： 本发明提供了鉴别和编码TPMP的人类甲状腺和垂体膜蛋白（TPMP）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供了用于诊断，治疗或预防与TPMP表达相关的障碍的方法。