公开(公告)号：US07685278B2

公开(公告)日：2010-03-23

申请号：US10026061

申请日：2001-12-18

申请人： Ira Cohen ,  Alexandre Bronstein ,  Marsha Prescott Duro

发明人： Ira Cohen ,  Alexandre Bronstein ,  Marsha Prescott Duro

IPC分类号： G06F15/173 ,  G06F15/18

CPC分类号： G06N7/005

摘要： A method for adapting a Bayesian network includes determining a set of parameters for the Bayesian network, for example, initial parameters, and then updating the parameters in response to a set of observation data using an adaptive learning rate. The adaptive learning rate responds to any changes in the underlying modeled environment using minimal observation data.

摘要翻译： 一种用于调整贝叶斯网络的方法包括确定贝叶斯网络的一组参数，例如初始参数，然后响应于一组观测数据使用自适应学习速率来更新参数。 自适应学习率使用最小观测数据来响应底层模拟环境中的任何变化。

公开(公告)号：US09002830B2

公开(公告)日：2015-04-07

申请号：US12834592

申请日：2010-07-12

申请人： Ira Cohen ,  Gilad Barash ,  Eli Mordechai ,  Carl Staelin

发明人： Ira Cohen ,  Gilad Barash ,  Eli Mordechai ,  Carl Staelin

IPC分类号： G06F17/30

CPC分类号： G06F17/30864 ,  G06F17/30011

摘要： A method of determining reliability of electronic documents associated with an event occurring in connection with a computing device may comprise, with a processor, composing a number of search queries based on text included in an event message, searching for a number of electronic documents via a network, said searching performed based on the composed search queries, and ranking the electronic documents identified by said searching based upon an indication of reliability in addressing the event associated with the event message, in which, ranking the electronic documents comprises applying a content source ranking criteria.

摘要翻译： 确定与计算设备相关联的事件相关联的电子文档的可靠性的方法可以包括与处理器基于事件消息中包含的文本来组合搜索查询的数量，经由以下操作搜索多个电子文档： 网络，基于所组合的搜索查询执行所述搜索，并且基于在解决与事件消息相关联的事件的可靠性的指示来对由所述搜索所识别的电子文档进行排名，其中，对电子文档进行排名包括应用内容源排名 标准

公开(公告)号：US20140229768A1

公开(公告)日：2014-08-14

申请号：US14342664

申请日：2011-09-21

申请人： Ruth Bernstein ,  Ira Cohen ,  Eran Samuni

发明人： Ruth Bernstein ,  Ira Cohen ,  Eran Samuni

IPC分类号： G06F11/34

CPC分类号： G06F11/3495 ,  G06F11/0709 ,  G06F11/079 ,  G06F11/3419 ,  H04L41/065 ,  H04L43/08 ,  H04L43/16

摘要： A method for automated detection of a real IT system problem may include obtaining monitor measurements of metrics associated with activities of a plurality of configuration items of the IT system. The method may also include detecting anomalies in the monitor measurements. The method may further include grouping concurrent anomalies of the detected anomalies corresponding to configuration items of the plurality of configuration items which are topologically linked to be regarded as a system anomaly. The method may further include calculating a significance score for the system anomaly, and determining that the system anomaly relates to a real system problem based on the calculated significance score.

摘要翻译： 用于自动检测真实IT系统问题的方法可以包括获得与IT系统的多个配置项的活动相关联的度量的监视器测量。 该方法还可以包括检测监视器测量中的异常。 所述方法还可以包括对与所述多个配置项目的配置项目相对应的检测到的异常的并发异常进行分组，所述配置项目被拓扑地链接以被认为是系统异常。 该方法还可以包括计算系统异常的显着性得分，并且基于所计算的显着性分数来确定系统异常与实际系统问题相关。

公开(公告)号：US20080110985A1

公开(公告)日：2008-05-15

申请号：US11975401

申请日：2007-10-19

申请人： Barry Cohen ,  Ira Cohen

发明人： Barry Cohen ,  Ira Cohen

IPC分类号： G07C13/00

CPC分类号： G07C13/00

摘要： A method is described that involves creating a private key and a public key cryptographic key pair, generating a unique and random identifier for a voter's vote and accepting an election vote from said voter. The vote and identifier are electronically signed with the private key to create a digital signature. The vote and identifier are provided in a human readable format to the voter. The digital signature is provided to the voter. The method further involves generating a second unique and random identifier for a second voter's vote and accepting a second election vote from the second voter. The second vote and identifier are electronically signed with the private key to create a second digital signature. The second vote and second identifier are provided in a human readable format to the second voter. The second digital signature is provided to the second voter. The public key is published on an internet. Information is publicly provided on the internet that associates together: (i) the voter's vote in a human readable format, (ii) the identifier in a human readable format, and (iii) the digital signature. The voter's vote is verifiable with the digital signature and the public key. Information is publicly provided on the internet that associates together: (iv) the second voter's vote in a human readable format, (v) the second identifier in a human readable format, and (vi) the second digital signature. The second voter's vote is verifiable with the second digital signature and the public key. The method includes, in response to receiving a request from the internet containing the identifier, providing (i), (ii) and (iii) above through an internet communication. The method also includes in response to receiving a second request from the internet containing the second identifier, providing (iv), (v) and (vi) above through a second internet communication.

摘要翻译： 描述了一种方法，其涉及创建私钥和公共密钥密码对，为选民投票产生唯一且随机的标识符，并接受所选投票者的选举投票。 投票和标识符用私钥用电子签名来创建数字签名。 投票和标识符以人类可读格式提供给选民。 数字签名提供给选民。 该方法还包括为第二选民投票产生第二唯一和随机的标识符，并从第二选民接受第二选举投票。 第二票和标识符用私钥电子签名以创建第二数字签名。 第二投票和第二标识符以人类可读格式提供给第二选民。 第二个数字签名被提供给第二个选民。 公共密钥在互联网上发布。 在互联网上公开提供信息，其联系在一起：（i）以人类可读格式投票，（ii）以人类可读格式的标识符，以及（iii）数字签名。 选民的投票可以通过数字签名和公钥来验证。 在互联网上公开提供信息，其联系在一起：（iv）第二选民以人类可读格式的投票，（v）以人类可读格式的第二标识符，和（vi）第二数字签名。 第二个选民投票可以通过第二个数字签名和公钥来验证。 该方法包括响应于从互联网接收到包含标识符的请求，通过互联网通信提供上述（i），（ii）和（iii）。 该方法还包括响应于从互联网接收包含第二标识符的第二请求，通过第二互联网通信提供上述（iv），（v）和（vi）。

公开(公告)号：US20070042347A1

公开(公告)日：2007-02-22

申请号：US11520527

申请日：2006-09-12

申请人： Michael Rosen ,  Richard Robinson ,  Ira Cohen ,  Han-Gang Yu

发明人： Michael Rosen ,  Richard Robinson ,  Ira Cohen ,  Han-Gang Yu

IPC分类号： C12Q1/00

CPC分类号： G01N33/6872 ,  A61K38/1709 ,  A61K48/00 ,  G01N33/5008 ,  G01N33/502 ,  G01N33/5061

摘要： This invention provides for a chamber and system designed for use in assaying drug effects on heart rate. The chamber consists of a series of wells, each 3 mm by 3 mm in inner diameter. Cardiac myocytes disaggregated from neonatal animals are plated onto the bottom of each well and grown under standard tissue culture conditions. The chamber holds from 24-96 such wells. When drugs are to be assayed, the cells in each well are loaded with a calcium sensitive dye and the beating rate in each is monitored with a photodiode. Drug is added in graded concentrations to each well, and equilibrated and effects on rate are observed. This construct permits use of a cell based bioassay for the study of drugs or agents that may alter cardiac rate. This invention can be used in high throughput screening of drugs to evaluate/predict their effects on cardiac rate and rhythm. Further provided for by this invention is a A vector which comprises a compound which encode an ion channel.

摘要翻译： 本发明提供了一种设计用于测定药物对心率的影响的室和系统。 该室由一系列的孔组成，内径为3 mm×3 mm。 将从新生儿动物分解的心肌细胞接种在每个孔的底部并在标准组织培养条件下生长。 该厅拥有24-96个这样的井。 当要测定药物时，每个孔中的细胞装载有钙敏感染料，并且用光电二极管监测每个孔中的搏动速率。 将药物以分级浓度加入每个孔中，并平衡并观察其对速率的影响。 该构建允许使用基于细胞的生物测定法来研究可能改变心率的药物或药剂。 本发明可用于药物的高通量筛选以评估/预测其对心率和节律的影响。 本发明进一步提供的是包含编码离子通道的化合物的A载体。

公开(公告)号：US20060234375A1

公开(公告)日：2006-10-19

申请号：US11240948

申请日：2005-09-29

申请人： Sergey Doronin ,  Ira Cohen ,  Peter Brink ,  Glenn Gaudette ,  Michael Rosen ,  Richard Robinson

发明人： Sergey Doronin ,  Ira Cohen ,  Peter Brink ,  Glenn Gaudette ,  Michael Rosen ,  Richard Robinson

IPC分类号： C12N5/08 ,  C12N5/00 ,  A01N63/00

CPC分类号： C12N5/0663 ,  A61K35/28 ,  A61K35/44 ,  A61K35/545

摘要： A method for treating a subject afflicted with a cardiac disorder, in vivo, comprising (i) producing a solution comprising media conditioned from the culture of cells, in vitro, and (ii) administering the solution of step (i) to the subject, thereby treating the cardiac disorder in the subject. Methods for determining whether an agent stimulates or inhibits myocyte proliferation.

摘要翻译： 一种用于在体内治疗患有心脏病症的受试者的方法，包括（i）在体外产生包含从细胞培养物调节的培养基的溶液，和（ii）向受试者施用步骤（i）的溶液， 从而治疗受试者的心脏病。 确定药物是否刺激或抑制肌细胞增殖的方法。

公开(公告)号：US20060198829A1

公开(公告)日：2006-09-07

申请号：US11227533

申请日：2005-09-14

申请人： Michael Rosen ,  Richard Robinson ,  Ira Cohen ,  Peter Brink ,  Glenn Gaudette ,  Irina Potapova

发明人： Michael Rosen ,  Richard Robinson ,  Ira Cohen ,  Peter Brink ,  Glenn Gaudette ,  Irina Potapova

IPC分类号： A61K48/00 ,  C12N5/08 ,  C12N15/87

CPC分类号： C12N5/0657

摘要： A method for treating a subject afflicted with a cardiac disorder, in vivo, comprises (i) inducing differentiation of a progenitor cell, in vitro, to a cardiogenic cell; and (ii) administering a therapeutically effective amount of the cardiogenic cell of step (i) to the subject, thereby treating the cardiac disorder in the subject. This invention further provides related articles of manufacture and methods.

公开(公告)号：US20060047614A1

公开(公告)日：2006-03-02

申请号：US10932386

申请日：2004-09-02

申请人： Ira Cohen ,  Moises Goldszmidt

发明人： Ira Cohen ,  Moises Goldszmidt

IPC分类号： G06N5/02 ,  G06N7/00 ,  G06F17/00 ,  G06N7/08

CPC分类号： G06K9/6277

摘要： A classifier is calibrated to produce a calibration map and a threshold is derived from the calibration map. A probability assignment produced by the classifier for input data is then compared to the threshold.

摘要翻译： 分类器被校准以产生校准图，并且从校准图导出阈值。 然后将用于输入数据的分类器产生的概率分配与阈值进行比较。

公开(公告)号：US10402484B2

公开(公告)日：2019-09-03

申请号：US14354115

申请日：2011-10-27

申请人： Shahar Golan ,  Omer Barkol ,  Ruth Bergman ,  Ira Cohen ,  Gal Noy

发明人： Shahar Golan ,  Omer Barkol ,  Ruth Bergman ,  Ira Cohen ,  Gal Noy

IPC分类号： G06F17/00 ,  G06F17/24 ,  G06F17/30

摘要： Methods and systems of aligning annotation of fields of documents are provided. Training information that includes first measurement information pertaining to features of each of a plurality of fields associated with training clusters for documents of a document type is accessed. A first training cluster is annotated with a first name and the second training cluster is annotated with a second name. An electronic classification model is generated based on the training information. Second measurement information for features of fields associated with new clusters of a new document is accessed. Each of the new clusters is automatically annotated based on the second measurement information using the classification model. For example, a first new cluster that has fields of the first field type is annotated with the first name and a second new cluster that has fields of the second field type is annotated with the second name.

公开(公告)号：US09087089B2

公开(公告)日：2015-07-21

申请号：US13700620

申请日：2010-06-09

申请人： Ruth Bernstein ,  Ira Cohen ,  Chen Kahana

发明人： Ruth Bernstein ,  Ira Cohen ,  Chen Kahana

IPC分类号： G06F17/30 ,  G06F9/44 ,  G06F11/36

CPC分类号： G06F17/30312 ,  G06F8/77 ,  G06F11/3616

摘要： A method and system comprise abstracting configuration items (CI) in at least a first anomaly and a second anomaly based on type of CI. Further, CIs are matched of a common type between the first and second anomalies based on a cost function. Additionally, a similarity score is computed for the first and second anomalies based, at least in part, on the cost function of the matched CI's and based on topology of the first and second anomalies.

摘要翻译： 方法和系统包括基于CI的类型抽象至少第一异常中的配置项（CI）和第二异常。 此外，基于成本函数，CI在第一和第二异常之间与普通类型匹配。 另外，至少部分地基于匹配的CI的成本函数并且基于第一和第二异常的拓扑来计算第一和第二异常的相似性得分。