公开(公告)号：US20110009774A1

公开(公告)日：2011-01-13

申请号：US12879500

申请日：2010-09-10

申请人： Irio Calasso ,  Patrick Griss ,  Emad Sarofim ,  Rainer Jaeggi ,  Uwe Kraemer ,  Dave Hasker ,  Volker Zimmer ,  Wilifried Schmid ,  Otto Fuerst ,  Hans List ,  Hans-Peter Haar ,  Theo Arnitz ,  Steven N. Roe

发明人： Irio Calasso ,  Patrick Griss ,  Emad Sarofim ,  Rainer Jaeggi ,  Uwe Kraemer ,  Dave Hasker ,  Volker Zimmer ,  Wilifried Schmid ,  Otto Fuerst ,  Hans List ,  Hans-Peter Haar ,  Theo Arnitz ,  Steven N. Roe

IPC分类号： A61B5/151

CPC分类号： A61B5/1411 ,  A61B5/14532 ,  A61B5/1486 ,  A61B5/150022 ,  A61B5/150068 ,  A61B5/150282 ,  A61B5/150358 ,  A61B5/150396 ,  A61B5/150419 ,  A61B5/150427 ,  A61B5/15045 ,  A61B5/150503 ,  A61B5/15151 ,  A61B5/15163

摘要： Body fluid sampling device comprising a skin-piercing element having a collection zone for receiving body fluid. In one embodiment, the collection zone includes a plurality of holes, e.g., 3 or more holes, or 50 to 100 holes. The hole size may be small, e.g., having a diameter of 0.01 to 0.5 mm. The holes may or may not extend through the lancet. In some embodiments, the holes have a depth of 50 to 500 μm. In other embodiments, the collection zone is porous, or is a roughened area. The collection zone can take up a very small volume of body fluid, e.g., 3 to 10 nL, in a very short time period, e.g., less than 0.5 seconds. In other embodiments, the device further comprises a fluid receiving means spaced apart from the collection zone so that body fluid in the collection zone will not contact the fluid receiving means initially.

摘要翻译： 体液取样装置包括具有用于接收体液的收集区的皮肤刺穿元件。 在一个实施例中，收集区包括多个孔，例如3个或更多个孔，或50至100个孔。 孔尺寸可以较小，例如具有0.01至0.5mm的直径。 这些孔可以延伸穿过刺血针也可能不延伸穿过刺血针。 在一些实施例中，孔的深度为50至500μm。 在其它实施方案中，收集区是多孔的，或者是粗糙区域。 收集区可以在非常短的时间段（例如小于0.5秒）内占据非常小体积的体液，例如3至10nL。 在其他实施例中，该装置还包括与收集区间隔开的流体接收装置，使得收集区中的体液最初不会接触流体接收装置。

公开(公告)号：US08814808B2

公开(公告)日：2014-08-26

申请号：US12879500

申请日：2010-09-10

申请人： Irio Guiseppe Calasso ,  Patrick Griss ,  Emad Sarofim ,  Rainer Jaeggi ,  Uwe Kraemer ,  Dave Hasker ,  Volker Zimmer ,  Wilifried Schmid ,  Otto Fuerst ,  Hans List ,  Hans-Peter Haar ,  Theo Arnitz ,  Steven N. Roe

发明人： Irio Guiseppe Calasso ,  Patrick Griss ,  Emad Sarofim ,  Rainer Jaeggi ,  Uwe Kraemer ,  Dave Hasker ,  Volker Zimmer ,  Wilifried Schmid ,  Otto Fuerst ,  Hans List ,  Hans-Peter Haar ,  Theo Arnitz ,  Steven N. Roe

IPC分类号： A61B5/151 ,  A61B5/15 ,  A61B5/145

CPC分类号： A61B5/1411 ,  A61B5/14532 ,  A61B5/1486 ,  A61B5/150022 ,  A61B5/150068 ,  A61B5/150282 ,  A61B5/150358 ,  A61B5/150396 ,  A61B5/150419 ,  A61B5/150427 ,  A61B5/15045 ,  A61B5/150503 ,  A61B5/15151 ,  A61B5/15163

摘要： Body fluid sampling device comprising a skin-piercing element having a collection zone for receiving body fluid. In one embodiment, the collection zone includes a plurality of holes, e.g., 3 or more holes, or 50 to 100 holes. The hole size may be small, e.g., having a diameter of 0.01 to 0.5 mm. The holes may or may not extend through the lancet. In some embodiments, the holes have a depth of 50 to 500 μm. In other embodiments, the collection zone is porous, or is a roughened area. The collection zone can take up a very small volume of body fluid, e.g., 3 to 10 nL, in a very short time period, e.g., less than 0.5 seconds. In other embodiments, the device further comprises a fluid receiving means spaced apart from the collection zone so that body fluid in the collection zone will not contact the fluid receiving means initially.

摘要翻译： 体液取样装置包括具有用于接收体液的收集区的皮肤刺穿元件。 在一个实施例中，收集区包括多个孔，例如3个或更多个孔，或50至100个孔。 孔尺寸可以较小，例如具有0.01至0.5mm的直径。 这些孔可以延伸穿过刺血针也可能不延伸穿过刺血针。 在一些实施例中，孔的深度为50至500μm。 在其它实施方案中，收集区是多孔的，或者是粗糙区域。 收集区可以在非常短的时间段（例如小于0.5秒）内占据非常小体积的体液，例如3至10nL。 在其他实施例中，该装置还包括与收集区间隔开的流体接收装置，使得收集区中的体液最初不会接触流体接收装置。

公开(公告)号：US20070016103A1

公开(公告)日：2007-01-18

申请号：US11470368

申请日：2006-09-06

申请人： Irio Calasso ,  Patrick Griss ,  Emad Sarofim ,  Rainer Jaeggi ,  Uwe Kraemer ,  Dave Hasker ,  Volker Zimmer ,  Wilfried Schmid ,  Otto Fuerst ,  Hans List ,  Hans-Peter Haar ,  Theo Arnitz ,  Steven Roe

发明人： Irio Calasso ,  Patrick Griss ,  Emad Sarofim ,  Rainer Jaeggi ,  Uwe Kraemer ,  Dave Hasker ,  Volker Zimmer ,  Wilfried Schmid ,  Otto Fuerst ,  Hans List ,  Hans-Peter Haar ,  Theo Arnitz ,  Steven Roe

IPC分类号： A61B5/00

CPC分类号： A61B5/1411 ,  A61B5/14532 ,  A61B5/1486 ,  A61B5/150022 ,  A61B5/150068 ,  A61B5/150282 ,  A61B5/150358 ,  A61B5/150396 ,  A61B5/150419 ,  A61B5/150427 ,  A61B5/15045 ,  A61B5/150503 ,  A61B5/15151 ,  A61B5/15163

摘要： Body fluid sampling device comprising a skin-piercing element having a collection zone for receiving body fluid, and the device further comprising a fluid receiving means remote spaced apart from the collection zone so that body fluid in the collection zone will not contact the fluid receiving means initially. The collection zone takes up a very small volume of body fluid of about 10 to 500 nl in a very short time period of less than 0.5 seconds. The fluid receiving means may have a test zone for performing an analytical reaction. Fluid sample from the collection zone is automatically or manually transported to the fluid receiving means to contact the fluid with the test zone.

摘要翻译： 体液取样装置包括具有用于接收体液的收集区的皮肤刺穿元件，并且该装置还包括与收集区间隔开的流体接收装置，使得收集区中的体液不会接触流体接收装置 原来。 收集区在小于0.5秒的非常短的时间段内占据非常小体积的体液约10至500nl。 流体接收装置可以具有用于进行分析反应的测试区域。 来自收集区的流体样品被自动或手动地输送到流体接收装置以使流体与测试区接触。

公开(公告)号：US07819822B2

公开(公告)日：2010-10-26

申请号：US11470368

申请日：2006-09-06

申请人： Irio Guiseppe Calasso ,  Patrick Griss ,  Emad Sarofim ,  Rainer Jaeggi ,  Uwe Kraemer ,  Dave Hasker ,  Volker Zimmer ,  Wilfried Schmid ,  Otto Fuerst ,  Hans List ,  Hans-Peter Haar ,  Theo Arnitz ,  Steven N. Roe

发明人： Irio Guiseppe Calasso ,  Patrick Griss ,  Emad Sarofim ,  Rainer Jaeggi ,  Uwe Kraemer ,  Dave Hasker ,  Volker Zimmer ,  Wilfried Schmid ,  Otto Fuerst ,  Hans List ,  Hans-Peter Haar ,  Theo Arnitz ,  Steven N. Roe

IPC分类号： A61B5/00

CPC分类号： A61B5/1411 ,  A61B5/14532 ,  A61B5/1486 ,  A61B5/150022 ,  A61B5/150068 ,  A61B5/150282 ,  A61B5/150358 ,  A61B5/150396 ,  A61B5/150419 ,  A61B5/150427 ,  A61B5/15045 ,  A61B5/150503 ,  A61B5/15151 ,  A61B5/15163

摘要： Body fluid sampling device comprising a skin-piercing element having a collection zone for receiving body fluid, and the device further comprising a fluid receiving means remote spaced apart from the collection zone so that body fluid in the collection zone will not contact the fluid receiving means initially. The collection zone takes up a very small volume of body fluid of about 10 to 500 nl in a very short time period of less than 0.5 seconds. The fluid receiving means may have a test zone for performing an analytical reaction. Fluid sample from the collection zone is automatically or manually transported to the fluid receiving means to contact the fluid with the test zone.

摘要翻译： 体液取样装置包括具有用于接收体液的收集区的皮肤刺穿元件，并且该装置还包括与收集区间隔开的流体接收装置，使得收集区中的体液不会接触流体接收装置 原来。 收集区在小于0.5秒的非常短的时间段内占据非常小体积的体液约10至500nl。 流体接收装置可以具有用于进行分析反应的测试区域。 来自收集区的流体样品被自动或手动地输送到流体接收装置以使流体与测试区接触。

公开(公告)号：US08444574B2

公开(公告)日：2013-05-21

申请号：US12396838

申请日：2009-03-03

申请人： Hans List ,  Irio G. Calasso ,  Joachim Hoenes ,  Hans-Peter Haar ,  Uwe Kraemer ,  Herbert Harttig ,  Volker Zimmer

发明人： Hans List ,  Irio G. Calasso ,  Joachim Hoenes ,  Hans-Peter Haar ,  Uwe Kraemer ,  Herbert Harttig ,  Volker Zimmer

IPC分类号： A61B5/00 ,  A61B17/32 ,  A61B17/14 ,  B65D81/00

CPC分类号： A61B5/14532 ,  A61B5/150022 ,  A61B5/150068 ,  A61B5/150175 ,  A61B5/150389 ,  A61B5/150503 ,  A61B5/15109 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/15132

摘要： Lancing system comprising a needle and a lancing device The lancing device comprises a housing with a housing opening that is surrounded by a housing skin contact surface. A lancing depth reference element with a reference skin contact surface is adapted in such a manner that the reference skin contact surface at a reversal point of the lancing movement is in contact with the skin. The lancing depth is determined by the distance between the reference skin contact surface and the tip of the needle element at the reversal point of the lancing movement. The lancing depth reference element is in a stationary defined position relative to the reversal point of the lancing movement. The lancing depth reference element is adapted to stabilize the skin when pressed against the reference skin contact surface with respect to a skin deformation which occurs upon lancing of the skin.

摘要翻译： 包括针和穿刺装置的牵引系统。该穿刺装置包括壳体，该外壳具有由壳体皮肤接触表面包围的壳体开口。 具有参考皮肤接触表面的穿刺深度参考元件以使得在穿刺运动的反转点处的参考皮肤接触表面与皮肤接触的方式被适配。 穿刺深度由穿刺运动的反转点处的参考皮肤接触表面和针元件的尖端之间的距离确定。 穿刺深度参考元件相对于穿刺运动的反转点处于静止的限定位置。 穿刺深度参考元件适于当相对于在皮肤穿刺时发生的皮肤变形而压靠参照皮肤接触表面时稳定皮肤。

公开(公告)号：US20100063417A1

公开(公告)日：2010-03-11

申请号：US12396838

申请日：2009-03-03

申请人： Hans List ,  Irio G. Calasso ,  Joachim Hoenes ,  Hans-Peter Haar ,  Uwe Kraemer ,  Herbert Harttig ,  Volker Zimmer

发明人： Hans List ,  Irio G. Calasso ,  Joachim Hoenes ,  Hans-Peter Haar ,  Uwe Kraemer ,  Herbert Harttig ,  Volker Zimmer

IPC分类号： A61B5/151

CPC分类号： A61B5/14532 ,  A61B5/150022 ,  A61B5/150068 ,  A61B5/150175 ,  A61B5/150389 ,  A61B5/150503 ,  A61B5/15109 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/15132

摘要： Lancing system for extracting a body fluid from the skin of a human or animal comprising a needle element (3) for lancing the skin, a lancing device (2) which includes a lancet drive (15a), by which a lancing movement of the needle element (3) coupled with the lancet drive by means of a coupling mechanism (28) is driven in lancing direction, wherein the lancing device (2) comprises a housing (4) with a housing opening (5) at its in lancing direction front end and the housing opening (5) is surrounded by a housing skin contact surface (7) which is pressed against the skin when using the lancing device (2), the needle element (3) is moved on a predetermined lancing path in a lancing direction in a forward phase of the lancing movement until its tip (3c) enters the skin in order to create a wound and in a return phase of the lancing movement following the reaching of a reversal point corresponding to the lancing depth (S) in the skin is retracted again, a lancing depth reference element (8) with a reference skin contact surface (11) is provided to improve the reproducibility of the lancing depth (S), which is adapted and arranged in such a manner that the reference skin contact surface (11) at the reversal point of the lancing movement is in contact with the skin and the predetermined value of the lancing depth (S) is determined by the distance in lancing direction which prevails at the reversal point of the lancing movement between the reference skin contact surface (11) and the position of the tip (3c) of the needle element (3), at which at the time at which the tip (3c) of the needle element (3) in the forward phase of the lancing movement passes the reference skin contact surface (11) and enters a skin surface which is in contact with said reference skin contact surface, the lancing depth reference element (8) with the reference skin contact surface (11) is in a stationary defined position relative to the reversal point of the lancing movement and the lancing depth reference element (8) is adapted and arranged in such a manner that the skin when pressed against the reference skin contact surface (11) is stabilized with respect to a skin deformation which occurs upon lancing of the skin.

公开(公告)号：US20090321287A1

公开(公告)日：2009-12-31

申请号：US12340241

申请日：2008-12-19

申请人： Hans List ,  Uwe Kraemer ,  Volker Zimmer ,  Steven N. Roe

发明人： Hans List ,  Uwe Kraemer ,  Volker Zimmer ,  Steven N. Roe

IPC分类号： B65D71/00 ,  A61B5/151

CPC分类号： B65D83/0472 ,  A61B5/150022 ,  A61B5/150358 ,  A61B5/150419 ,  A61B5/150702 ,  A61B5/15128 ,  A61B5/15151 ,  A61B5/15167 ,  A61B5/15169 ,  A61B5/15173 ,  A61B5/15176 ,  A61B5/15184 ,  A61B50/3001

摘要： A system comprising disposable medical devices and a packaging strip comprising a plurality of chambers containing the disposable medical devices. The strip is folded along breadthwise running fold lines to form a series of loops, each loop comprising opposing sections. The opposing sections of at least some of these loops are sealed to each other thus forming chambers between said sections. A cartridge contains such a packaging strip.

摘要翻译： 一种包括一次性医疗装置和包含多个容纳一次性医疗装置的腔室的包装带的系统。 条带沿着宽度方向的折叠线折叠以形成一系列环，每个环包括相对的部分。 这些环中的至少一些的相对部分彼此密封，从而在所述部分之间形成室。 墨盒包含这样的包装条。

公开(公告)号：US08020703B2

公开(公告)日：2011-09-20

申请号：US12340241

申请日：2008-12-19

申请人： Hans List ,  Uwe Kraemer ,  Volker Zimmer ,  Steven N. Roe

发明人： Hans List ,  Uwe Kraemer ,  Volker Zimmer ,  Steven N. Roe

IPC分类号： B65D69/00 ,  B65D83/10

CPC分类号： B65D83/0472 ,  A61B5/150022 ,  A61B5/150358 ,  A61B5/150419 ,  A61B5/150702 ,  A61B5/15128 ,  A61B5/15151 ,  A61B5/15167 ,  A61B5/15169 ,  A61B5/15173 ,  A61B5/15176 ,  A61B5/15184 ,  A61B50/3001

摘要： A system comprising disposable medical devices and a packaging strip comprising a plurality of chambers containing the disposable medical devices. The strip is folded along breadthwise running fold lines to form a series of loops, each loop comprising opposing sections. The opposing sections of at least some of these loops are sealed to each other thus forming chambers between said sections. A cartridge contains such a packaging strip.

摘要翻译： 一种包括一次性医疗装置和包含多个容纳一次性医疗装置的腔室的包装带的系统。 条带沿着宽度方向的折叠线折叠以形成一系列环，每个环包括相对的部分。 这些环中的至少一些的相对部分彼此密封，从而在所述部分之间形成室。 墨盒包含这样的包装条。

公开(公告)号：US20070213682A1

公开(公告)日：2007-09-13

申请号：US11373902

申请日：2006-03-13

申请人： Hans-Peter Haar ,  Hans List ,  Irio Calasso

发明人： Hans-Peter Haar ,  Hans List ,  Irio Calasso

IPC分类号： A61M31/00

CPC分类号： A61B5/15192 ,  A61B5/150022 ,  A61B5/150068 ,  A61B5/150412 ,  A61B5/150503 ,  A61B5/15107 ,  A61B5/15115 ,  A61B5/15117 ,  A61B5/15123 ,  A61B5/15125 ,  A61B5/15128 ,  A61B5/1519 ,  A61B10/0045

摘要： The present invention provides a method and device for extracting body fluid from a body part. The method provides a penetration device including a penetration element formed to pierce the body part and an actuator formed to propel forward movement of the penetration element. The penetration element is moved toward the body part at a very high penetration speed to form an impression in the body part having a depth less than about 0.3 mm and the body part is pierced with the penetration element. The actuator of the penetration device is formed to propel forward movement of the penetration element at a penetration speed of at least about 15 m/sec.

摘要翻译： 本发明提供一种用于从身体部分提取体液的方法和装置。 该方法提供一种穿透装置，其包括形成为刺穿身体部分的穿透元件和形成为推动穿透元件的向前运动的致动器。 穿透元件以非常高的穿透速度朝向身体部分移动，以在身体部分中形成深度小于约0.3mm并且身体部分被穿透元件刺穿的印象。 穿透装置的致动器形成为以至少约15m /秒的穿透速度推进穿透元件的向前运动。

公开(公告)号：US20080214909A1

公开(公告)日：2008-09-04

申请号：US11816770

申请日：2006-02-21

申请人： Otto Fuerst ,  Hans List ,  Hans-Peter Haar

发明人： Otto Fuerst ,  Hans List ,  Hans-Peter Haar

IPC分类号： A61B5/00

CPC分类号： A61B5/6865 ,  A61B5/14514 ,  A61B5/14532 ,  A61B5/150022 ,  A61B5/150213 ,  A61B5/150229 ,  A61B5/150282 ,  A61B5/150358 ,  A61B5/150389 ,  A61B5/150511 ,  A61B5/15105 ,  A61B5/155 ,  A61B5/157 ,  A61B5/6852 ,  A61B2010/008 ,  A61B2562/0295 ,  Y10T29/49826

摘要： Catheter for monitoring the concentration of an analyte in a body fluid having an implantable distal area (7) for the uptake of body fluids and a proximal area (8) with an outlet opening (14), wherein the catheter comprises a catheter casing (1) having microopenings which are permeable to at least part of the body fluid and at least partially hold back corpuscular components, and a catheter core (2) which is located in the catheter casing (1). The catheter core preferably has a microstructure on its peripheral surface and/or the catheter casing has a microstructure on its inner wall which form a hollow space between the catheter core and catheter casing. Moreover the invention concerns a method for the manufacture of such a catheter.

摘要翻译： 导管，其用于监测具有用于摄取体液的可植入远侧区域（7）的体液中的分析物的浓度以及具有出口开口（14）的近端区域（8），其中所述导管包括导管套管（1） ），其具有对于体液的至少一部分是可渗透的并且至少部分地阻止红细胞成分的微开口，以及位于导管壳体（1）中的导管芯（2）。 导管芯优选在其外周表面上具有微结构，和/或导管外壳在其内壁上具有形成在导管芯和导管外壳之间的中空空间的微结构。 此外，本发明涉及制造这种导管的方法。