Use of inhibitors of leukotriene B4 receptor BLT2 for treating human cancers
    1.
    发明授权
    Use of inhibitors of leukotriene B4 receptor BLT2 for treating human cancers 有权
    使用白三烯B4受体BLT2抑制剂治疗人类癌症

    公开(公告)号:US08288357B2

    公开(公告)日:2012-10-16

    申请号:US12450335

    申请日:2008-03-24

    IPC分类号: A61K31/70 C07H21/02 C07H21/04

    摘要: The present invention relates to a new use of inhibitors of leukotriene B4 receptor BLT2 for treating human cancers. More particularly, the present invention relates to a pharmaceutical composition for treating human cancers comprising BLT2 inhibitors and a method for treating human cancers using BLT2 inhibitors.The present inventors revealed the role of BLT2 as a survival factor of human cancers, such as bladder, prostate, pancreatic, and breast cancer and found that the BLT2 inhibitors can be used as anti-cancer drugs. The present inventors revealed that BLT2 has an important role in metastasis of cancer cells and angiogenesis of tumor and demonstrated that the anti-cancer activity of the BLT2 inhibitors is accomplished by inducing the apoptosis of cancer cells, inhibiting the metastasis of cancer cells, or inhibiting the angiogenesis of tumor.

    摘要翻译: 本发明涉及白三烯B4受体BLT2抑制剂治疗人类癌症的新用途。 更具体地,本发明涉及用于治疗包含BLT2抑制剂的人类癌症的药物组合物和使用BLT2抑制剂治疗人类癌症的方法。 本发明人揭示了BLT2作为人类癌症如膀胱,前列腺,胰腺和乳腺癌的存活因子的作用,发现BLT2抑制剂可用作抗癌药物。 本发明人发现BLT2在癌细胞转移和肿瘤血管生成中具有重要作用,并且证明BLT2抑制剂的抗癌活​​性是通过诱导癌细胞的凋亡,抑制癌细胞的转移或抑制 肿瘤血管生成。

    SEMICONDUCTOR DEVICE AND METHOD FOR FABRICATING THE SAME
    6.
    发明申请
    SEMICONDUCTOR DEVICE AND METHOD FOR FABRICATING THE SAME 有权
    半导体器件及其制造方法

    公开(公告)号:US20150061067A1

    公开(公告)日:2015-03-05

    申请号:US14337811

    申请日:2014-07-22

    IPC分类号: H01L29/872 H01L29/36

    摘要: A semiconductor device includes an epitaxial layer of a first conductive type; an anode electrode and a cathode electrode arranged on the epitaxial layer to be separated from each other; a first drift layer of the first conductive type formed in the epitaxial layer; a Schottky contact area at a region of contact between the anode electrode and the first drift layer; an impurity region of a second conductive type different from the first conductive type at the epitaxial layer; and an insular impurity region formed below the Schottky contact area.

    摘要翻译: 半导体器件包括第一导电类型的外延层; 布置在所述外延层上以彼此分离的阳极电极和阴极电极; 在外延层中形成的第一导电类型的第一漂移层; 在阳极电极和第一漂移层之间的接触区域处的肖特基接触区域; 在外延层处不同于第一导电类型的第二导电类型的杂质区; 以及形成在肖特基接触区域下方的岛状杂质区域。

    STORAGE DEVICE AND OPERATING METHOD OF STORAGE DEVICE
    8.
    发明申请
    STORAGE DEVICE AND OPERATING METHOD OF STORAGE DEVICE 有权
    存储设备的存储设备和操作方法

    公开(公告)号:US20160147452A1

    公开(公告)日:2016-05-26

    申请号:US14885409

    申请日:2015-10-16

    IPC分类号: G06F3/06

    摘要: An operating method of a storage device which includes a nonvolatile memory and a memory controller configured to control the nonvolatile memory, may include tracking a clock signal; entering a vendor mode of the storage device when the clock signal corresponds to a vendor pattern; and maintaining a normal mode of the storage device when the clock signal does not correspond to the vendor pattern, wherein, in the normal mode, a command received from an external host device is executed according to a first rule, and wherein, in the vendor mode, the command received from the external host device is executed according to a second rule different from the first rule.

    摘要翻译: 包括非易失性存储器和被配置为控制非易失性存储器的存储器控​​制器的存储设备的操作方法可以包括跟踪时钟信号; 当时钟信号对应于供应商模式时,进入存储设备的供应商模式; 以及当所述时钟信号不对应于所述供应商模式时,保持所述存储设备的正常模式,其中,在所述正常模式中,根据第一规则执行从外部主机设备接收到的命令,并且其中,在所述供应商中 根据与第一规则不同的第二规则执行从外部主机装置接收的命令。

    Method of context aware data-centric storage for wireless sensor networks
    9.
    发明授权
    Method of context aware data-centric storage for wireless sensor networks 有权
    用于无线传感器网络的上下文感知以数据为中心的存储方法

    公开(公告)号:US08521924B2

    公开(公告)日:2013-08-27

    申请号:US13338759

    申请日:2011-12-28

    IPC分类号: G06F13/00 G06F3/00

    CPC分类号: H04W4/38 H04W84/18

    摘要: There is provided a method of context aware data-centric storage for dynamically changing a data storage range comprising: collecting data from entire sensor nodes, after establishing a data storage range of an entire sensor network, dividing areas, and transmitting a message of data storage range information to the entire sensor nodes by a base station; storing the collected data in a storage sensor node by determining whether there is a node responsible for storing the collected data to carry out operation depending on the determination result; determining whether the data storage has not been carried out for a period of time longer than a specified time in each sensor node after storing the data; and to determining whether the scale of invalid range is not smaller than Γ.

    摘要翻译: 提供了一种用于动态改变数据存储范围的上下文感知数据中心存储的方法,包括:在建立整个传感器网络的数据存储范围,分割区域和传送数据存储器的消息之后,从整个传感器节点收集数据 由基站向整个传感器节点提供范围信息; 通过确定是否存在负责存储收集的数据的节点,以根据确定结果来执行操作来将收集的数据存储在存储传感器节点中; 在存储数据之后,确定数据存储器是否在每个传感器节点中比指定时间长的时间段内未被执行; 并确定无效范围是否不小于Gamma。

    Joint box for connecting high voltage cables
    10.
    发明授权
    Joint box for connecting high voltage cables 失效
    用于连接高压电缆的接线盒

    公开(公告)号:US08512077B2

    公开(公告)日:2013-08-20

    申请号:US13132298

    申请日:2010-03-02

    IPC分类号: H01R13/66

    摘要: A device for connecting high voltage cable having a connection element comprising of first and second sleeves, each having a protrusion on a top for receiving first and second conductors of a first and second high voltage cables and fixing the first and second conductors by pressure; a contact bump being coupled to the protrusion in a sliding manner and an electrode unit having a key hole that the contact bump contacts with, wherein the first and second sleeves are coupled in a manner of male and female coupling.

    摘要翻译: 一种用于连接高压电缆的装置,具有包括第一和第二套筒的连接元件,每个连接元件在顶部具有突起,用于接收第一和第二高压电缆的第一和第二导体,并通过压力固定第一和第二导体; 接触凸块以滑动方式联接到所述突起部,以及电极单元,所述电极单元具有所述接触凸块接触的键孔,其中所述第一和第二套筒以阳联接和阴联接的方式联接。