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公开(公告)号：US09358342B2
公开(公告)日：2016-06-07
申请号：US13519793
申请日：2011-02-01
CPC分类号： A61M5/284 , A61M5/2425 , A61M5/2448 , A61M5/282 , A61M5/3146 , A61M5/31525 , A61M5/3155 , A61M5/326 , A61M5/3294 , A61M5/3297 , A61M5/347 , A61M2005/1787 , A61M2005/3267
摘要： A reservoir (31) with at least one flexible section for use in a medicated module (4) for an injection system to co-deliver at least two medicaments is disclosed where a primary delivery device (7) containing a first medicament accepts a medicated module (4) containing a single dose of a second medicament (2) and where both medicaments are delivered through a single hollow needle (3). The reservoir (31) comprises one or more slit valves (44, 45) to allow for delivery of the first and second medicaments. The medicated module (4) also contains a needle guard (22) that engages a housing (43) of the reservoir (31) to open the slit valves (44, 45).
摘要翻译： 公开了一种具有至少一个柔性部分的储存器（31），用于在用于注射系统的药物模块（4）中共同递送至少两种药物的柔性部分，其中包含第一药物的主要输送装置（7）接受药物模块 （4），其含有单剂量的第二药物（2），并且其中两种药物通过单个中空针（3）递送。 储存器（31）包括一个或多个狭缝阀（44,45），以允许第一和第二药物的输送。 所述药物模块（4）还包含与所述储存器（31）的壳体（43）接合以打开所述狭缝阀（44,45）的针护罩（22）。
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公开(公告)号：US20130018323A1
公开(公告)日：2013-01-17
申请号：US13519793
申请日：2011-02-01
CPC分类号： A61M5/284 , A61M5/2425 , A61M5/2448 , A61M5/282 , A61M5/3146 , A61M5/31525 , A61M5/3155 , A61M5/326 , A61M5/3294 , A61M5/3297 , A61M5/347 , A61M2005/1787 , A61M2005/3267
摘要： A reservoir (31) with at least one flexible section for use in a medicated module (4) for an injection system to co-deliver at least two medicaments is disclosed where a primary delivery device (7) containing a first medicament accepts a medicated module (4) containing a single dose of a second medicament (2) and where both medicaments are delivered through a single hollow needle (3). The reservoir (31) comprises one or more slit valves (44, 45) to allow for delivery of the first and second medicaments. The medicated module (4) also contains a needle guard (22) that engages a housing (43) of the reservoir (31) to open the slit valves (44, 45).
摘要翻译： 公开了一种具有至少一个柔性部分的储存器（31），用于在用于注射系统的药物模块（4）中共同递送至少两种药物的柔性部分，其中包含第一药物的主要输送装置（7）接受药物模块 （4），其含有单剂量的第二药物（2），并且其中两种药物通过单个中空针（3）递送。 储存器（31）包括一个或多个狭缝阀（44,45），以允许第一和第二药物的输送。 所述药物模块（4）还包含与所述储存器（31）的壳体（43）接合以打开所述狭缝阀（44,45）的针护罩（22）。
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公开(公告)号：US09352103B2
公开(公告)日：2016-05-31
申请号：US13576632
申请日：2011-02-01
CPC分类号： A61M5/3245 , A61M5/2448 , A61M5/2466 , A61M5/284 , A61M5/288 , A61M5/3146 , A61M5/31525 , A61M5/3155 , A61M5/326 , A61M5/3294 , A61M5/3297 , A61M5/347 , A61M5/5086 , A61M2005/1787 , A61M2005/3247 , A61M2005/3267 , A61M2205/583
摘要： A medicated module for an injection system to co-deliver at least two medicaments is disclosed. The drug delivery device includes a push rod operably connected to a dose dial button. The medicated module includes a housing having a connector configured for attachment to the drug delivery device, and the housing is configured to receive a portion of the push rod when the medicated module is attached to the drug delivery device. The medicated module further includes a reservoir in the housing comprising a single dose of a medicament and a needle guard operably connected to the housing and configured to move in an axial direction during application to an injection site. Still further, the medicated module includes a sleeve in the housing configured to move axially in the housing and a locking collar in the housing configured to move axially and rotationally in the housing.
摘要翻译： 公开了一种用于共同递送至少两种药物的注射系统的药物组合物。 药物递送装置包括可操作地连接到剂量拨号按钮的推杆。 所述药物模块包括具有连接器的壳体，所述连接器构造成用于附接到所述药物输送装置，并且所述壳体构造成当所述药物模块附接到所述药物输送装置时接收所述推杆的一部分。 所述药物模块还包括在所述壳体中的储存器，其包括单个剂量的药物和针护罩，所述药剂和针护罩可操作地连接到所述壳体并且构造成在施加到注射部位期间在轴向方向上移动。 另外，所述药物模块包括壳体中的套筒，所述套筒构造成在所述壳体中轴向移动，并且所述壳体中的锁定套环构造成在所述壳体中轴向和旋转地移动。
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公开(公告)号：US20130090604A1
公开(公告)日：2013-04-11
申请号：US13576632
申请日：2011-02-01
IPC分类号： A61M5/32
CPC分类号： A61M5/3245 , A61M5/2448 , A61M5/2466 , A61M5/284 , A61M5/288 , A61M5/3146 , A61M5/31525 , A61M5/3155 , A61M5/326 , A61M5/3294 , A61M5/3297 , A61M5/347 , A61M5/5086 , A61M2005/1787 , A61M2005/3247 , A61M2005/3267 , A61M2205/583
摘要： A medicated module for an injection system to co-deliver at least two medicaments is disclosed. The drug delivery device includes a push rod operably connected to a dose dial button. The medicated module includes a housing having a connector configured for attachment to the drug delivery device, and the housing is configured to receive a portion of the push rod when the medicated module is attached to the drug delivery device. The medicated module further includes a reservoir in the housing comprising a single dose of a medicament and a needle guard operably connected to the housing and configured to move in an axial direction during application to an injection site. Still further, the medicated module includes a sleeve in the housing configured to move axially in the housing and a locking collar in the housing configured to move axially and rotationally in the housing.
摘要翻译： 公开了一种用于共同递送至少两种药物的注射系统的药物组合物。 药物递送装置包括可操作地连接到剂量拨号按钮的推杆。 所述药物模块包括具有连接器的壳体，所述连接器构造成用于附接到所述药物输送装置，并且所述壳体构造成当所述药物模块附接到所述药物输送装置时接收所述推杆的一部分。 所述药物模块还包括在所述壳体中的储存器，其包括单个剂量的药物和针护罩，所述药剂和针护罩可操作地连接到所述壳体并且构造成在施加到注射部位期间在轴向方向上移动。 另外，所述药物模块包括壳体中的套筒，所述套筒构造成在所述壳体中轴向移动，并且所述壳体中的锁定套环构造成在所述壳体中轴向和旋转地移动。
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公开(公告)号：US20130018310A1
公开(公告)日：2013-01-17
申请号：US13520364
申请日：2011-02-01
CPC分类号： A61M5/284 , A61M5/2448 , A61M5/3146 , A61M5/31525 , A61M5/3155 , A61M5/326 , A61M5/3294 , A61M5/347 , A61M2005/1787 , A61M2005/3128 , A61M2005/3247 , A61M2005/3267
摘要： A medicated module (4) for an injection system to co-deliver at least two medicaments is disclosed where a primary delivery device (7) containing a primary medicament accepts a medicated module (4) containing a single dose of a second medicament (2) and where both medicaments are delivered through a single hollow needle (3). The medicated module (4) contains a time lock feature to prevent further use after a predetermined time elapses. The medicated module (4) can also contain a rotary valve (19) operably connected to a retractable needle shield (16) that locks after a predetermined time elapses.
摘要翻译： 公开了一种用于共同递送至少两种药物的注射系统的药物组合物（4），其中含有主要药物的主要递送装置（7）接受含有单剂量第二药物（2）的药物组合物（4） 并且其中两种药物通过单个空心针（3）递送。 药物模块（4）包含时间锁定功能，以防止在经过预定时间后进一步使用。 药物模块（4）还可以包含可操作地连接到可预定时间过去之后锁定的可缩回的针护罩（16）的旋转阀（19）。
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公开(公告)号：US09402963B2
公开(公告)日：2016-08-02
申请号：US13576701
申请日：2011-02-01
CPC分类号： A61M5/3202 , A61M5/2448 , A61M5/284 , A61M5/288 , A61M5/3129 , A61M5/3146 , A61M5/31525 , A61M5/3155 , A61M5/326 , A61M5/3294 , A61M5/3297 , A61M5/347 , A61M2005/1787 , A61M2005/3247 , A61M2005/3267 , A61M2205/583
摘要： A medicated module for an injection system to co-deliver at least two medicaments is disclosed, where a drug delivery device containing a primary medicament accepts a medicated module containing a single dose of a second medicament and where both medicaments are delivered through a single hollow needle. The medicated module comprises two housings removably connected to each other, where each housing contains a sterile needle and needle guard assembly that locks out after the needle is inserted in an injection site.
摘要翻译： 公开了一种用于共同递送至少两种药物的注射系统的药物组合物，其中包含主要药物的药物递送装置接受含有单剂量第二药物的药物组合物，并且其中两种药物通过单个中空针 。 所述药物模块包括可移除地彼此连接的两个壳体，其中每个壳体包含在针插入注射部位之后锁定的无菌针头和护针组件。
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公开(公告)号：US09352092B2
公开(公告)日：2016-05-31
申请号：US13322092
申请日：2010-06-01
申请人： James Alexander Davies , Steven Wimpenny , Daniel Thomas De Sausmarez Lintell , Malcolm Stanley Boyd , Naceur Rekaya , Simon Lewis Bilton , John David Cross
发明人： James Alexander Davies , Steven Wimpenny , Daniel Thomas De Sausmarez Lintell , Malcolm Stanley Boyd , Naceur Rekaya , Simon Lewis Bilton , John David Cross
IPC分类号： A61M5/31 , A61M5/32 , A61M5/24 , A61M5/34 , A61M5/00 , A61M5/178 , A61M5/28 , A61M3/00 , A61M5/14 , A61M5/20 , A61J1/20 , A61M5/315 , A61M5/50
CPC分类号： A61M5/2448 , A61J1/20 , A61J1/2065 , A61J1/2089 , A61J1/2096 , A61M3/005 , A61M5/1407 , A61M5/1409 , A61M5/1413 , A61M5/2066 , A61M5/2466 , A61M5/284 , A61M5/31525 , A61M5/31556 , A61M5/3294 , A61M5/3297 , A61M5/34 , A61M5/50 , A61M2005/1787 , A61M2005/3142 , A61M2206/20
摘要： A medicated module for an injection system to co-deliver at least two medicaments is disclosed where a primary delivery device containing a primary medicament accepts a medicated module containing a single dose of a secondary medicament contained within a capsule having an integral flow distributor/distribution system and where both medicaments are delivered through a single hollow needle.
摘要翻译： 公开了一种用于共同递送至少两种药物的注射系统的药物组合物，其中包含主要药物的主要递送装置接受含有单剂量次级药物的药物组合物，该药剂组合物包含在具有整体式流动分配器/分配系统 并且其中两种药物通过单个空心针递送。
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公开(公告)号：US08979791B2
公开(公告)日：2015-03-17
申请号：US13322096
申请日：2010-06-01
申请人： James Alexander Davies , Steven Wimpenny , Daniel Thomas De Sausmarez Lintell , Malcolm Stanley Boyd , Naceur Rekaya , Simon Lewis Bilton , John David Cross
发明人： James Alexander Davies , Steven Wimpenny , Daniel Thomas De Sausmarez Lintell , Malcolm Stanley Boyd , Naceur Rekaya , Simon Lewis Bilton , John David Cross
CPC分类号： A61M5/284 , A61M5/204 , A61M5/288 , A61M5/31525 , A61M5/326 , A61M5/3294 , A61M5/3297 , A61M5/347 , A61M2005/1787 , A61M2005/3142 , A61M2005/3247 , A61M2005/3267
摘要： A medicated module comprising a connecting body configured for attachment to a drug delivery device. A first needle is fixed within the connecting body and an outer body operatively coupled to the connecting body. A needle guard operatively coupled to the outer body and a biasing member positioned between the outer body and needle guard. A second needle fixed within the outer body and a recess within the connecting body defines a reservoir. The reservoir contains at least one dose of a medicament and is configured for fluid communication with the first and second needle.
摘要翻译： 一种药物模块，包括构造成附接到药物递送装置的连接体。 第一针固定在连接体内，外部体可操作地连接到连接体。 可操作地联接到外主体的针护罩和定位在外体和针护罩之间的偏置构件。 固定在外主体内的第二针和在连接体内的凹部限定一储存器。 储存器包含至少一剂剂量的药物，并且构造成用于与第一针和第二针流体连通。
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公开(公告)号：US20120226238A1
公开(公告)日：2012-09-06
申请号：US13322097
申请日：2010-06-01
申请人： James Alexander Davies , Steven Wimpenny , Daniel Thomas De Sausmarez Lintell , Malcolm Stanley Boyd , Naceur Rekaya , Simon Lewis Bilton , John David Cross
发明人： James Alexander Davies , Steven Wimpenny , Daniel Thomas De Sausmarez Lintell , Malcolm Stanley Boyd , Naceur Rekaya , Simon Lewis Bilton , John David Cross
CPC分类号： A61M5/284 , A61J1/20 , A61J1/2089 , A61M5/1409 , A61M5/1413 , A61M5/204 , A61M5/2066 , A61M5/288 , A61M5/31525 , A61M5/326 , A61M5/3294 , A61M5/3297 , A61M5/347 , A61M2005/1787 , A61M2005/3142 , A61M2005/3247 , A61M2005/3267
摘要： A medicated module attachable to a drug delivery device comprises a connecting body configured for attachment to the drug delivery device. A first needle is fixed within the connecting body and a movable needle hub is operatively coupled to the connecting body. A needle guard is operatively coupled to the connecting body and a biasing member is positioned between the connecting body and needle guard. A second needle is fixed within the needle hub. A first cavity within the connecting body defines a reservoir containing at least one dose of a medicament. The reservoir configured for fluid communication with the first and the second needle. The reservoir comprises a bypass configured to allow medicament from the drug delivery device to bypass the reservoir and exit the second needle.
摘要翻译： 可附接到药物递送装置的药物模块包括构造成附接到药物递送装置的连接体。 第一针固定在连接体内，并且可动针座可操作地联接到连接体。 针护罩可操作地联接到连接体，并且偏置构件定位在连接体和针护罩之间。 第二针固定在针座内。 连接体内的第一腔体限定含有至少一剂药物的储液器。 储存器被配置成与第一和第二针流体连通。 储存器包括旁路，其构造成允许来自药物输送装置的药物绕过储存器并离开第二针。
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公开(公告)号：US20120220949A1
公开(公告)日：2012-08-30
申请号：US13322092
申请日：2010-06-01
申请人： James Alexander Davies , Steven Wimpenny , Daniel Thomas De Sausmarez Lintell , Malcolm Stanley Boyd , Naceur Rekaya , Simon Lewis Bilton , John David Cross
发明人： James Alexander Davies , Steven Wimpenny , Daniel Thomas De Sausmarez Lintell , Malcolm Stanley Boyd , Naceur Rekaya , Simon Lewis Bilton , John David Cross
CPC分类号： A61M5/2448 , A61J1/20 , A61J1/2065 , A61J1/2089 , A61J1/2096 , A61M3/005 , A61M5/1407 , A61M5/1409 , A61M5/1413 , A61M5/2066 , A61M5/2466 , A61M5/284 , A61M5/31525 , A61M5/31556 , A61M5/3294 , A61M5/3297 , A61M5/34 , A61M5/50 , A61M2005/1787 , A61M2005/3142 , A61M2206/20
摘要： A medicated module for an injection system to co-deliver at least two medicaments is disclosed where a primary delivery device containing a primary medicament accepts a medicated module containing a single dose of a secondary medicament contained within a capsule having an integral flow distributor/distribution system and where both medicaments are delivered through a single hollow needle.
摘要翻译： 公开了一种用于共同递送至少两种药物的注射系统的药物组合物，其中包含主要药物的主要递送装置接受含有单剂量次级药物的药物组合物，该药剂组合物包含在具有整体式流动分配器/分配系统 并且其中两种药物通过单个空心针递送。
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