摘要:
An apparatus for multiple simultaneous synthesis (110), having a number of vials (28), each vial (28) having an upper end (31), a lower end (30), and a barrel (29), the upper end (31) opening into a mouth (32). It also includes a lower frame assembly (180) having a number of holes (101, 103, 105) for receiving the vials (28), and an upper frame assembly (180), which includes inner side-walls (195) and a ceiling portion (190). A gas-tight seal (197) surrounds a plenum (85), the plenum (85) being formed between the ceiling portion (190) of the upper frame assembly (180) and the lower frame assembly (181). The plenum (85) is adjustable in volume by the positioning of the upper frame assembly (180) in variable relation to the lower frame assembly (181), while maintaining the gas-tight seal (197). The volume of the plenum (85) is adjustable to a minimum whereby the mouths (32) of the vials (28) are sealed by the ceiling (190) of the gas-tight seal (197), which is optionally an upper gasket (90). Also disclosed is a plenum enclosure (182) for multiple simultaneous synthesis used in conjunction with vials (28), which includes the upper frame assembly (180) and lower frame assembly (181) and the gastight seal (197), as well as a gasket vial holder (185) to be used in the plenum enclosure (182).
摘要:
An improved multi-well synthesis and filtration apparatus (10) includes a deep-well synthesis block (12) having a plurality of flowthrough wells (24) optionally fitted with filter disks (48) each of the wells (24) being integrally formed in the synthesis block (12), such that any material placed in the wells (24) is in immediate contact with the material of the synthesis block (12), an upper cover (14), a lower cover (16), and a pair of first and second sheet gaskets (18, 20). The first and second sheet gaskets (18, 20) are interposed between the upper and lower covers (14, 16) to seal inlet portions (38) and outlet spouts (40) of the wells (24). The upper and lower covers (14, 16) are independently releasable, and, with the gaskets (18, 20) form a gas tight seal, so that material is retained in the wells (24) when the lower cover (16) is removed, but the upper seal maintained. Apertures (70) in the upper cover (14) provide that the first sheet gasket (18) may be punctured for introduction of materials and/or maintenance of an inert atmosphere. An alternative synthesis block (412) having half the number of wells (424) but configured to be able to use a collection plate (123) of the same array as the first embodiment is also described.
摘要:
A multi-well synthesis and filtration apparatus (10) dimensionally arrayed in a standard multi-well format for performing multiple chemical reactions includes a deep-well synthesis block (12) with flowthrough wells (24) fitted with filter disks (48), an upper cover (14), and a lower cover (16). First and second sheet gaskets (18 and 20) seal inlet portions (38) and outlet spouts (40) of the wells (24). An optional skirt (26) provides a site for the independently releasable attachment of the upper and lower covers (14 and 16) to the block (12) while maintaining the seal on the unreleased cover. An alternative synthesis apparatus (310) additionally includes a reinforcement assembly (372) to improve the clamping action of the covers (14 and 16) upon the synthesis block (12). A rotating carrier apparatus (200) and a modified oven assembly (202) are provided to enable agitation and heating of multiple synthesis blocks (12) simultaneously.
摘要:
A syringe array (10) for holding a plurality of syringes (12), each syringe having a barrel (14), a plunger (18) and a needle (16), the syringe array (10) including a distal assembly (50) which holds the plungers (18) of the plurality of syringes (12) and by which all of the plurality of plungers (18) are urged to move in unison, a pivot assembly (52) wherein a portion of each the barrels (14) of the plurality of syringes (12) is pivotally attached to a pivot (92, 94) and a proximal assembly (48) wherein each needle (16) of the plurality of syringes (12) is positioned with a controlled center-to-center spacing (100, 102) from each other. An adjusting portion (62, 64, 70) of the syringe array (10) is adjustable to controllably change the needle center-to-center spacing from a first spacing (100) to at least a second spacing (102) as the barrel portions (14) are allowed to rotate about the pivots (92, 94).
摘要:
A syringe with replaceable needle assembly (10), having a syringe barrel (18) with a proximal end (14), a distal end (16), and an outer surface (87). The syringe barrel (18) surrounds an internal bore (20). A plunger assembly (60) is inserted into the syringe barrel internal bore (20). A needle assembly (80) has a sealing portion (72), which is configured to be removably insertable into the internal bore (20). The sealing portion (72) forms a fluid-tight seal with the internal bore (20). The needle assembly (80) further includes a releasable locking mechanism (79), which includes a collar (76) having a locking flange (86). Also disclosed is a replaceable needle assembly (80), which releasably locks onto the outer surface (87) of the proximal end (14) of a syringe barrel (18). The replaceable needle assembly (80) includes a collar (76), having a locking flange (86), which engages the outer surface (87) of the syringe barrel (18), and releasably locks the replaceable needle assembly (80) onto the syringe barrel (18).
摘要:
A classification system and method are provided, wherein the classification system includes a memory device, a processor communicatively connected to the memory device, and an input communicatively connected to the processor, wherein the input is configured to receive data comprising at least one object that is to be classified as one of an object of interest (OOI) and a nuisance of interest (NOI) based upon at least one non-Boolean attribute of the object, wherein the processor is configured as a Bayesian classifier to classify the object based upon the non-Boolean attribute using a non-linear probability function.
摘要:
A classification system and method are provided, wherein the classification system includes a memory device, a processor communicatively connected to the memory device, and an input communicatively connected to the processor, wherein the input is configured to receive data comprising at least one object that is to be classified as one of an object of interest (OOI) and a nuisance of interest (NOI) based upon at least one non-Boolean attribute of the object, wherein the processor is configured as a Bayesian classifier to classify the object based upon the non-Boolean attribute using a non-linear probability function.
摘要:
A system comprises a structure editor, a structure library, an extractor and a user interface, which are stored in computer memory and create structures for recognizing patterns in computer text. The structure editor via the user interface enables a user to input a text string called a model pattern, and uses previously-created structures such as lexical category structures for parsing the model pattern into default definition items. Each default definition item includes attributes specifying the patterns recognizable by the definition item and relationships with other definition items. The structure editor enables and facilitates user modification of the default definition items by generating attribute choices for user selection and allowing a user to generate a new structure if none of the choices is adequate. The resulting definition items form a new definition of a new structure, which is stored in the structure library. The extractor locates a pattern in computer text by satisfying the conditions of a definition of a new structure.
摘要:
A fluidized bed condenser for use in condensing zirconium tetrachloride or hafnium tetrachloride vapor into solid zirconium tetrachloride or hafnium tetrachloride includes a scraper assembly. The scraper assembly includes at least one scraper arm located adjacent an inlet through which fluid zirconium tetrachloride or hafnium tetrachloride enters the condenser vessel. A cleanout rod is also mounted on the vessel to clean out the inlet, and the scraper includes a cleanout assembly for preventing build up of solid material in a solid outlet area defined in the vessel.