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192 条记录 (耗时 0.058 秒)

    Rod-In-Tube optical fiber preform assembly and method having reduced movement
    2.
    发明申请
    Rod-In-Tube optical fiber preform assembly and method having reduced movement 有权
    棒管式光纤预制组件和方法运动减小

    公开(公告)号：US20050064188A1

    公开(公告)日：2005-03-24

    申请号：US10665623

    申请日：2003-09-19

    申请人： Joseph Fletcher ,  Andrew Jones ,  Thomas Miller ,  Don Smith ,  Shunhe Xiong

    发明人： Joseph Fletcher ,  Andrew Jones ,  Thomas Miller ,  Don Smith ,  Shunhe Xiong

    IPC分类号： D02G3/00

    CPC分类号： C03B37/02754 ,  C03B37/01211 ,  C03B2205/14 ,  C03B2205/16 ,  Y10T428/2933 ,  Y10T428/2964

    摘要： Embodiments of the invention include an optical fiber preform assembly and a method for making optical fiber using the preform assembly. The assembly includes a preform core rod, at least one overclad tube formed around the preform core rod, a handle attached to one end of the overclad tube, and a refractory material positioned in the overclad tube between the preform core rod and the handle. The refractory material reduces if not prevents movement of the preform core rod into the handle during the fiber draw process. Preferably, the refractory material is made of, e.g., magnesium oxide and/or aluminum oxide, and has a melting point, e.g., greater than approximately 2000 degrees Celsius. Embodiments of the invention also include a method for making optical fiber using this preform assembly.

    摘要翻译： 本发明的实施例包括光纤预制组件和使用该预制组件制造光纤的方法。 该组件包括预制棒芯棒，至少一个围绕预制棒芯棒形成的外包层管，附接到外包层管的一端的手柄，以及位于预型芯棒和把手之间的外包层管中的耐火材料。 如果不是在纤维拉伸过程中防止预成型芯棒移动到把手中，则耐火材料减少。 优选地，耐火材料由例如氧化镁和/或氧化铝制成，并且具有例如大于约2000摄氏度的熔点。 本发明的实施例还包括使用该预制组件制造光纤的方法。

    Modular commercial microwave oven
    4.
    发明授权
    Modular commercial microwave oven 有权
    模块化商用微波炉

    公开(公告)号：US08367990B2

    公开(公告)日：2013-02-05

    申请号：US12783938

    申请日：2010-05-20

    申请人： Thomas Miller ,  Robert A. Schulte ,  Kami Poppen ,  Deborah Parenza

    发明人： Thomas Miller ,  Robert A. Schulte ,  Kami Poppen ,  Deborah Parenza

    IPC分类号： H05B6/80

    CPC分类号： H05B6/6426

    摘要： A microwave oven cabinet is ergonomic designed to provide for both stacking and jigsaw-type back-to-back interlining of multiple units of the microwave ovens. In particular, the cabinet configuration advantageously establishes a reduced footprint, ergonomically designed microwave oven which can be effectively employed in various fields, including fast food chains wherein multiple such ovens may need to be functionally positioned in a limited area, while still being easily accessible.

    摘要翻译： 微波炉柜符合人体工程学设计，可提供多台微波炉的堆叠和拼图型背对背衬布。 特别地，橱柜配置有利地建立了减少的占地面积，符合人体工程学设计的微波炉，其可以有效地用于各种领域，包括快餐食品链，其中多个这样的烤箱可能需要在有限的区域中功能地定位，同时仍然易于接近。

    Benzothiophene hydroxamic acid derivatives
    10.
    发明授权
    Benzothiophene hydroxamic acid derivatives 有权
    苯并噻吩异羟肟酸衍生物

    公开(公告)号：US07772238B2

    公开(公告)日：2010-08-10

    申请号：US11918912

    申请日：2006-04-14

    申请人： Jed Lee Hubbs ,  Sam Kattar ,  Joey Methot ,  Thomas Miller ,  Phieng Siliphaivanh ,  Matthew Stanton ,  Kevin Wilson ,  David J. Witter

    发明人： Jed Lee Hubbs ,  Sam Kattar ,  Joey Methot ,  Thomas Miller ,  Phieng Siliphaivanh ,  Matthew Stanton ,  Kevin Wilson ,  David J. Witter

    IPC分类号： A61K31/496 ,  A61K31/381 ,  C07D405/04 ,  C07D333/56

    CPC分类号： C07D333/70 ,  A61K31/38 ,  A61K31/381 ,  A61K31/41

    摘要： The present invention relates to a novel class of hydroxamic acid derivatives. The hydroxamic acid compounds can be used to treat cancer. The hydroxamic acid compounds can also inhibit histone deacetylase and are suitable for use in selectively inducing terminal differentiation, and arresting cell growth and/or apoptosis of neoplastic cells, thereby inhibiting proliferation of such cells. Thus, the compounds of the present invention are useful in treating a patient having a tumor characterized by proliferation of neoplastic cells. The compounds of the invention are also useful in the prevention and treatment of TRX-mediated diseases, such as autoimmune, allergic and inflammatory diseases, and in the prevention and/or treatment of diseases of the central nervous system (CNS), such as neurodegenerative diseases. The present invention further provides pharmaceutical compositions comprising the hydroxamic acid derivatives and safe dosing regimens of these pharmaceutical compositions, which are easy to follow, and which result in a therapeutically effective amount of the hydroxamic acid derivatives in vivo.

    摘要翻译： 本发明涉及一类新型异羟肟酸衍生物。 异羟肟酸化合物可用于治疗癌症。 异羟肟酸化合物也可以抑制组蛋白脱乙酰酶，适用于选择性诱导终末分化，阻止肿瘤细胞的细胞生长和/或凋亡，从而抑制这些细胞的增殖。 因此，本发明的化合物可用于治疗具有以肿瘤细胞增殖为特征的肿瘤的患者。 本发明的化合物还可用于预防和治疗TRX介导的疾病，例如自身免疫性，过敏性和炎性疾病，以及预防和/或治疗中枢神经系统（CNS）的疾病，例如神经变性 疾病 本发明进一步提供包含异羟肟酸衍生物和这些药物组合物的安全投药方案的药物组合物，它们易于遵循，并且其在体内导致治疗有效量的异羟肟酸衍生物。