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1.发明申请Method for the three-dimensional representation of a moving structure by a tomographic method 有权通过断层摄影法对移动结构进行三维表示的方法公开(公告)号：US20090092225A1
公开(公告)日：2009-04-09
申请号：US12221938
申请日：2008-08-07
申请人： Jan Boese , Wolfgang Harer , Michael Zellerhoff
发明人： Jan Boese , Wolfgang Harer , Michael Zellerhoff
CPC分类号： A61B6/025 , A61B6/027 , A61B6/4441 , A61B6/466 , A61B6/481 , A61B6/503 , A61B6/504 , A61B6/507 , G06T11/006 , G06T2211/404 , G06T2211/412 , G06T2211/436
摘要： The invention relates to a method for a three-dimensional representation of a moving structure by a tomographic method, in which during one recording pass a series of projection recordings is registered by an imaging unit at different recording angles between a start position and an end position, it being possible to reconstruct three-dimensional image data from the projection recordings with the following steps: a) generation of tomosynthesis projection recordings along a tomosynthesis scanning path; b) interpolation of the data of the tomosynthesis projection recordings in accordance with an interpolation algorithm in order to generate a projection data set; c) use of a tomosynthesis reconstruction method on the projection data set in order to generate a tomosynthesis volume image; d) repetition of steps b) and c) for all times of interest, and e) display of tomosynthesis representations from the tomosynthesis volume images.
摘要翻译： 本发明涉及一种用于通过断层摄影方法对运动结构进行三维表示的方法，其中在一次记录通过期间，成像单元以起始位置和结束位置之间的不同记录角度登记一系列投影记录 可以通过以下步骤从投影记录重建三维图像数据：a）沿着断层合成扫描路径生成断层合成投影记录; b）根据插值算法对所述断层合成投影记录的数据进行插值，以生成投影数据集; c）在投影数据集上使用断层合成重建方法，以便产生断层合成体积图像; d）对所有感兴趣的时间重复步骤b）和c），以及e）从断层合成体积图像显示断层合成表示。
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2.发明申请公开(公告)号：US20080031403A1
公开(公告)日：2008-02-07
申请号：US11888882
申请日：2007-08-02
申请人： Wolfgang Harer , Michael Zellerhoff
发明人： Wolfgang Harer , Michael Zellerhoff
CPC分类号： A61B6/02 , A61B6/4458
摘要： In a known type of tomosynthesis x-ray source and x-ray detector are linearly moved and x-rays images are taken for a large number of positions, the images being reconstructed to give a 3D image record. According to the invention x-ray source and x-ray detector are swiveled and a sequence of x-rays is subsequently taken again, x-ray source and x-ray detector again being moved in a straight line. One drawback of simple tomosynthesis with movement in a straight line is suppressed thereby, the drawback being that the quality of reconstruction is particularly poor in a certain direction.
摘要翻译： 在已知类型的断层合成中，X射线源和X射线检测器被线性移动，并且对于大量的位置拍摄X射线图像，重建图像以给出3D图像记录。 根据本发明，X射线源和X射线检测器被旋转，并且随后再次取得一系列X射线，x射线源和X射线检测器再次以直线移动。 抑制了直线运动的简单断层合成的一个缺点在于其重要性在一定方向上特别差。
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3.发明申请Method and device for the separate three-dimensional representation of arteries and veins in an examination object and device 有权用于检查对象和装置中动脉和静脉的单独三维表示的方法和装置公开(公告)号：US20090080736A1
公开(公告)日：2009-03-26
申请号：US12283419
申请日：2008-09-11
申请人： Wolfgang Harer , Michael Zellerhoff
发明人： Wolfgang Harer , Michael Zellerhoff
IPC分类号： G06K9/00
CPC分类号： A61B6/504 , A61B6/466 , A61B6/481 , Y10S378/901
摘要： There is described a method for a separate three-dimensional representation of arteries and/or veins of a vascular system in an examination object by means of a tomography x-ray device with the following steps: Implementation of a mask pass of the x-ray device with N projections at N angular positions about the examination object without contrast agent; Implementation of a first filler pass of the x-ray device about the examination object with M projections at M of the N angular positions after injection of a contrast agent, where M
摘要翻译： 描述了通过以下步骤通过断层摄影x射线装置对检查对象中的血管系统的动脉和/或静脉进行单独的三维表示的方法：执行x射线的掩模通过 装置，N个投影在关于没有造影剂的检查对象的N个角位置处; 在注射造影剂后，在N个角位置的M处实施X射线装置关于检查对象的第一填充物通过，其中M
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公开(公告)号：US08054941B2
公开(公告)日：2011-11-08
申请号：US12507818
申请日：2009-07-23
IPC分类号： H05G1/64 , H05G1/60 , H05G1/58 , G01N23/083
摘要： The invention relates to a method for the production of angiography recordings. First, a mask image is recorded with a first modality. A contrast medium is injected after the first recording. A control image is recorded with a second modality after the injection of the contrast medium. A spreading of the contrast medium is determined based on the images and the control of subsequent recordings is analyzed. A recording criterion is checked to determine whether the recording criterion has been achieved. If it has not been achieved, the control image is repeatedly recorded for repeatedly determining the spreading of the contrast medium. If it has been achieved, a contrast image is recorded with the first modality and the mask image and the contrast image are processed and analyzed.
摘要翻译： 本发明涉及一种生产血管造影记录的方法。 首先，以第一模式记录掩模图像。 在第一次记录之后注射造影剂。 在注射造影剂之后，以第二模态记录控制图像。 基于图像确定造影剂的扩展，并分析后续记录的控制。 检查记录标准以确定是否已经实现了记录标准。 如果还没有实现，则重复记录控制图像以重复确定造影剂的扩展。 如果已经实现，则用第一模态记录对比度图像，并且处理和分析掩模图像和对比度图像。
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5.发明授权Method for the three-dimensional representation of a moving structure by a tomographic method 有权通过断层摄影法对移动结构进行三维表示的方法公开(公告)号：US07899152B2
公开(公告)日：2011-03-01
申请号：US12221938
申请日：2008-08-07
申请人： Jan Boese , Wolfgang Härer , Michael Zellerhoff
发明人： Jan Boese , Wolfgang Härer , Michael Zellerhoff
IPC分类号： A61B6/00
CPC分类号： A61B6/025 , A61B6/027 , A61B6/4441 , A61B6/466 , A61B6/481 , A61B6/503 , A61B6/504 , A61B6/507 , G06T11/006 , G06T2211/404 , G06T2211/412 , G06T2211/436
摘要： The invention relates to a method for a three-dimensional representation of a moving structure by a tomographic method, in which during one recording pass a series of projection recordings is registered by an imaging unit at different recording angles between a start position and an end position, it being possible to reconstruct three-dimensional image data from the projection recordings with the following steps: a) generation of tomosynthesis projection recordings along a tomosynthesis scanning path; b) interpolation of the data of the tomosynthesis projection recordings in accordance with an interpolation algorithm in order to generate a projection data set; c) use of a tomosynthesis reconstruction method on the projection data set in order to generate a tomosynthesis volume image; d) repetition of steps b) and c) for all times of interest, and e) display of tomosynthesis representations from the tomosynthesis volume images.
摘要翻译： 本发明涉及一种用于通过断层摄影方法对运动结构进行三维表示的方法，其中在一次记录通过期间，成像单元以起始位置和结束位置之间的不同记录角度登记一系列投影记录 可以通过以下步骤从投影记录重建三维图像数据：a）沿着断层合成扫描路径生成断层合成投影记录; b）根据插值算法对所述断层合成投影记录的数据进行插值，以生成投影数据集; c）在投影数据集上使用断层合成重建方法，以便产生断层合成体积图像; d）对所有感兴趣的时间重复步骤b）和c），以及e）从断层合成体积图像显示断层合成表示。
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公开(公告)号：US20100027751A1
公开(公告)日：2010-02-04
申请号：US12507818
申请日：2009-07-23
摘要： The invention relates to a method for the production of angiography recordings. First, a mask image is recorded with a first modality. A contrast medium is injected after the first recording. A control image is recorded with a second modality after the injection of the contrast medium. A spreading of the contrast medium is determined based on the images and the control of subsequent recordings is analyzed. A recording criterion is checked to determine whether the recording criterion has been achieved. If it has not been achieved, the control image is repeatedly recorded for repeatedly determining the spreading of the contrast medium. If it has been achieved, a contrast image is recorded with the first modality and the mask image and the contrast image are processed and analyzed.
摘要翻译： 本发明涉及一种生产血管造影记录的方法。 首先，以第一模式记录掩模图像。 在第一次记录之后注射造影剂。 在注射造影剂之后，以第二模态记录控制图像。 基于图像确定造影剂的扩展，并分析后续记录的控制。 检查记录标准以确定是否已经实现了记录标准。 如果还没有实现，则重复记录控制图像以重复确定造影剂的扩展。 如果已经实现，则用第一模态记录对比度图像，并且处理和分析掩模图像和对比度图像。
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7.发明授权System and method of automatic estimation of arterial input function for evaluation of blood flow 有权自动估计动脉输入功能评估血流量的系统和方法公开(公告)号：US08488861B2
公开(公告)日：2013-07-16
申请号：US12245373
申请日：2008-10-03
CPC分类号： A61B6/481 , A61B5/055 , A61B6/4441 , A61B6/504 , A61B6/507
摘要： A system and method of determining hemodynamic parameters of a patient is described. A background image data set is obtained prior to the administration of a contrast agent. A series of image data sets is obtained during the first passage of the bolus through a parenchymal volume. The pre-contrast-agent image is subtracted from image data sets obtained during the first passage of the contrast agent bolus, so that the amount of contrast agent in the volume may be determined. The time series of the amount of contrast agent is computed to determine the arterial input function (AIF) which may be used to determine a tissue impulse response, and hemodynamic parameters such as cerebral blood flow (CBF), cerebral blood volume (CBV) and mean transit time (MTT).
摘要翻译： 描述了确定患者的血液动力学参数的系统和方法。 在施用造影剂之前获得背景图像数据集。 在推注通过实质体积的第一次通过期间获得一系列图像数据集。 在造影剂推注的第一次通过期间获得的图像数据集中减去预造影剂图像，从而可以确定体积中造影剂的量。 计算造影剂量的时间序列以确定可用于确定组织脉冲响应的动脉输入功能（AIF），以及血液动力学参数，例如脑血流量（CBF），脑血容量（CBV）和 平均通行时间（MTT）。
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8.发明申请SYSTEM AND METHOD OF AUTOMATIC ESTIMATION OF ARTERIAL INPUT FUNCTION FOR EVALUATION OF BLOOD FLOW 有权用于评估血液流动的输入函数的自动估计系统和方法公开(公告)号：US20090092308A1
公开(公告)日：2009-04-09
申请号：US12245373
申请日：2008-10-03
CPC分类号： A61B6/481 , A61B5/055 , A61B6/4441 , A61B6/504 , A61B6/507
摘要： A system and method of determining hemodynamic parameters of a patient is described. A background image data set is obtained prior to the administration of a contrast agent. A series of image data sets is obtained during the first passage of the bolus through a parenchymal volume. The pre-contrast-agent image is subtracted from image data sets obtained during the first passage of the contrast agent bolus, so that the amount of contrast agent in the volume may be determined. The time series of the amount of contrast agent is computed to determine the arterial input function (AIF) which may be used to determine a tissue impulse response, and hemodynamic parameters such as cerebral blood flow (CBF), cerebral blood volume (CBV) and mean transit time (MTT).
摘要翻译： 描述了确定患者的血液动力学参数的系统和方法。 在施用造影剂之前获得背景图像数据集。 在推注通过实质体积的第一次通过期间获得一系列图像数据集。 在造影剂推注的第一次通过期间获得的图像数据集中减去预造影剂图像，从而可以确定体积中造影剂的量。 计算造影剂量的时间序列以确定可用于确定组织脉冲响应的动脉输入功能（AIF），以及血液动力学参数，例如脑血流量（CBF），脑血容量（CBV）和 平均通行时间（MTT）。
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9.发明授权Method for the three-dimensional representation of a structure influenced by a periodic process, and medical imaging system 有权用于周期性过程影响的结构的三维表示的方法，以及医学成像系统公开(公告)号：US07953267B2
公开(公告)日：2011-05-31
申请号：US11881379
申请日：2007-07-26
申请人： Michael Zellerhoff
发明人： Michael Zellerhoff
CPC分类号： G01N23/046 , A61B6/481 , A61B6/503 , A61B6/504 , A61B6/541 , G01N2223/419 , G01N2223/612
摘要： There is described a method for a periodic and three-dimensional representation of a periodically variable structure. A number of rotation images is generated for this purpose. The required rotations relating to the same event of the periodic process are started at intervals offset by a defined angle. From the rotation images, new image series are assembled with which three-dimensional representations relating to different phase ranges of the period are reconstructed.
摘要翻译： 描述了周期性和三维表示周期性变化结构的方法。 为此目的生成多个旋转图像。 与周期性过程的相同事件有关的所需旋转以间隔偏移定义的角度开始。 从旋转图像，组装新图像系列，重建与周期的不同相位范围有关的三维表示。
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10.发明申请Method and apparatus for generating a functional data set of a perfused region of the human or animal body 有权用于产生人或动物体的灌注区域的功能数据集的方法和装置公开(公告)号：US20100246916A1
公开(公告)日：2010-09-30
申请号：US12729269
申请日：2010-03-23
CPC分类号： A61B6/504 , A61B6/481 , A61B6/507 , A61B6/5235 , A61B2090/364
摘要： A method and apparatus for generating at least one functional data set of a perfused region of the human or animal body are proposed. A first image data set is supplied comprising at least two images of the perfused region recorded at different times before and after an injection of contrast agent into a first artery supplying the region. A second image data set is supplied comprising at least two images of the perfused region recorded at different times before and after an injection of contrast agent into a second artery supplying the region. A first functional data set is generated by pixel-based calculation of at least one perfusion parameter from the first image data set. A second functional data set is generated by pixel-based calculation of at least one perfusion parameter from the second image data set.
摘要翻译： 提出了一种用于产生人体或动物身体的灌注区域的至少一个功能数据集的方法和装置。 提供第一图像数据组，其包括在将造影剂注射到供应该区域的第一动脉之前和之后的不同时间记录的灌注区域的至少两个图像。 提供第二图像数据集，其包括在将造影剂注射到供应该区域的第二动脉之前和之后的不同时间记录的灌注区域的至少两个图像。 通过基于来自第一图像数据集的至少一个灌注参数的基于像素的计算来生成第一功能数据集。 通过基于来自第二图像数据集的至少一个灌注参数的基于像素的计算来生成第二功能数据集。
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